価格表

在庫・価格 : 2024年05月22日 07時21分 現在

商品名 商品コード メーカー 包装 価格 在庫 リスト
Anti-Carbonic Anhydrase IX, Rabbit-Poly
データシート
NB100-417 NOVノバス バイオロジカルス
Novus biologicals, LLC
0.1 ml ¥103,000 1個 追加

在庫・価格 : 2024年05月22日 07時21分 現在

Anti-Carbonic Anhydrase IX, Rabbit-Poly

  • 商品コード:NB100-417
  • メーカー:NOV
  • 包装:0.1ml
  • 価格: ¥103,000
  • 在庫:1個
使用文献
No. 文献情報 備考 参照
1 Yoo H et al. Expression of the hypoxia marker carbonic anhydrase 9 is associated with anaplastic phenotypes in meningiomas. Clin. Cancer Res. 2007 Jan;13(1):68-75
Yoo H et al
2007/01/01
PubMed
2 Westbury CB et al. Hypoxia can be detected in irradiated normal human tissue: a study using the hypoxic marker pimonidazole hydrochloride. Br J Radiol 2007 Nov;80(959):934-8
Westbury CB et al
2007/01/01
PubMed
3 Kaidi A et al. Is the downregulation of EphB2 receptor expression during colorectal tumorigenesis due to hypoxia? Gut 2007 Nov;56(11):1637-8
Kaidi A et al
2007/01/01
PubMed
4 Sathornsumetee S et al. Tumor angiogenic and hypoxic profiles predict radiographic response and survival in malignant astrocytoma patients treated with bevacizumab and irinotecan. J. Clin. Oncol. 2008 Jan;26(2):271-8
Sathornsumetee S et al
2008/01/01
PubMed
5 Van den Eynden GG et al. Angiogenesis and hypoxia in lymph node metastases is predicted by the angiogenesis and hypoxia in the primary tumour in patients with breast cancer. Br. J. Cancer 2005 Nov;93(10):1128-36
Van den Eynden GG et al
2005/01/01
PubMed
6 Lapinski JE et al. Distinguishing clear cell renal cell carcinoma, retroperitoneal paraganglioma, and adrenal cortical lesions on limited biopsy material: utility of immunohistochemical markers. Appl. Immunohistochem. Mol. Morphol. 2010 Oct;18(5):414-21
Lapinski JE et al
2010/01/01
PubMed
7 M端ller J. [Recent evaluation of a Candida hemagglutination test]. Mycoses 1991;34 Suppl 1:63-7
M端ller J
1991/01/01
PubMed
8 Gabai VL et al. Heat shock transcription factor Hsf1 is involved in tumor progression via regulation of hypoxia-inducible factor 1 and RNA-binding protein HuR. Mol. Cell. Biol. 2012 Mar;32(5):929-40
Gabai VL et al
2012/01/01
PubMed
9 Ogino T et al. Inclusive estimation of complex antigen presentation functions of monocyte-derived dendritic cells differentiated under normoxia and hypoxia conditions. Cancer Immunol. Immunother. 2012 Mar;61(3):409-24
Ogino T et al
2012/01/01
PubMed
10 Garcia-Parra R et al. Investigation on tumor hypoxia in resectable primary prostate cancer as demonstrated by 18F-FAZA PET/CT utilizing multimodality fusion techniques. Eur. J. Nucl. Med. Mol. Imaging 2011 Oct;38(10):1816-23
Garcia-Parra R et al
2011/01/01
PubMed
11 Li Y et al. Role of hypoxia and EGF on expression, activity, localization and phosphorylation of carbonic anhydrase IX in MDA-MB-231 breast cancer cells. Biochim. Biophys. Acta 2011 Jan;1813(1):159-67
Li Y et al
2011/01/01
PubMed
12 Sakata K et al. Brachytherapy for oral tongue cancer: an analysis of treatment results with various biological markers. Jpn. J. Clin. Oncol. 2008 Jun;38(6):402-7
Sakata K et al
2008/01/01
PubMed
13 Wang Y et al. Hypoxia promotes ligand-independent EGF receptor signaling via hypoxia-inducible factor-mediated upregulation of caveolin-1. Proc. Natl. Acad. Sci. U.S.A. 2012 Mar;109(13):4892-7
Wang Y et al
2012/01/01
PubMed
14 Chamboredon S et al. Hypoxia-inducible factor-1α mRNA: a new target for destabilization by tristetraprolin in endothelial cells. Mol. Biol. Cell 2011 Sep;22(18):3366-78
Chamboredon S et al
2011/01/01
PubMed
15 Chaumeil MM et al. Hyperpolarized 13C MR spectroscopic imaging can be used to monitor Everolimus treatment in vivo in an orthotopic rodent model of glioblastoma. Neuroimage 2012 Jan;59(1):193-201
Chaumeil MM et al
2012/01/01
PubMed
16 Al-Ahmadie HA et al. Role of immunohistochemistry in the evaluation of needle core biopsies in adult renal cortical tumors: an ex vivo study. Am. J. Surg. Pathol. 2011 Jul;35(7):949-61
Al-Ahmadie HA et al
2011/01/01
PubMed
17 Lucio-Eterovic AK et al. Mediators of glioblastoma resistance and invasion during antivascular endothelial growth factor therapy. Clin. Cancer Res. 2009 Jul;15(14):4589-99
Lucio-Eterovic AK et al
2009/01/01
PubMed
18 Loinard C et al. Inhibition of prolyl hydroxylase domain proteins promotes therapeutic revascularization. Circulation 2009 Jul;120(1):50-9
Loinard C et al
2009/01/01
PubMed
19 Atkins M et al. Carbonic anhydrase IX expression predicts outcome of interleukin 2 therapy for renal cancer. Clin. Cancer Res. 2005 May;11(10):3714-21
Atkins M et al
2005/01/01
PubMed
20 Guise CP et al. Diflavin oxidoreductases activate the bioreductive prodrug PR-104A under hypoxia. Mol. Pharmacol. 2012 Jan;81(1):31-40
Guise CP et al
2012/01/01
PubMed
21 Chen J et al. Hypoxia-mediated up-regulation of Pim-1 contributes to solid tumor formation. Am. J. Pathol. 2009 Jul;175(1):400-11
Chen J et al
2009/01/01
PubMed
22 Benito J et al. Pronounced hypoxia in models of murine and human leukemia: high efficacy of hypoxia-activated prodrug PR-104. PLoS ONE 2011;6(8):e23108
Benito J et al
2011/01/01
PubMed
23 Ba単uelos CA et al. gammaH2AX expression in tumors exposed to cisplatin and fractionated irradiation. Clin. Cancer Res. 2009 May;15(10):3344-53
Ba単uelos CA et al
2009/01/01
PubMed
24 Melvin A et al. The chromatin remodeler ISWI regulates the cellular response to hypoxia: role of FIH. Mol. Biol. Cell 2011 Nov;22(21):4171-81
Melvin A et al
2011/01/01
PubMed
25 Narita T et al. Identification of a novel small molecule HIF-1alpha translation inhibitor. Clin. Cancer Res. 2009 Oct;15(19):6128-36
Narita T et al
2009/01/01
PubMed
26 Mackenzie KA et al. Angiogenesis and host immune response contribute to the aggressive character of non-melanoma skin cancers in renal transplant recipients. Histopathology 2011 May;58(6):875-85
Mackenzie KA et al
2011/01/01
Applications: IHC, Species: Human PubMed
27 Jung JH et al. Lowered expression of galectin-2 is associated with lymph node metastasis in gastric cancer. J. Gastroenterol. 2012 Jan;47(1):37-48
Jung JH et al
2012/01/01
Applications: WB, Species: Human PubMed
28 Deschamps L et al. The expression of the hypoxia markers CA9 and CXCR4 is correlated with survival in patients with neuroendocrine tumours of the ileum. Neuroendocrinology 2012;95(3):214-22
Deschamps L et al
2012/01/01
Applications: IHC, Species: Human PubMed
29 Lim CS et al. Increased activation of the hypoxia-inducible factor pathway in varicose veins. J. Vasc. Surg. 2012 May;55(5):1427-39
Lim CS et al
2012/01/01
Applications: WB, Species: Human PubMed
30 Matsumura Y et al. Morphophenotypic characteristics of intralymphatic cancer and stromal cells susceptible to lymphogenic metastasis. Cancer Sci 2012 Mar;
Matsumura Y et al
2012/01/01
Applications: IHC, Species: Human PubMed
31 Speisky D et al. Molecular profiling of pancreatic neuroendocrine tumors in sporadic and Von Hippel-Lindau patients. Clin. Cancer Res. 2012 May;18(10):2838-49
Speisky D et al
2012/01/01
Applications: IHC, Species: Human PubMed
32 Onishi H et al. Hedgehog inhibitor decreases chemosensitivity to 5-fluorouracil and gemcitabine under hypoxic conditions in pancreatic cancer. Cancer Sci 2012 Apr;
Onishi H et al
2012/01/01
Applications: IHC, IF, Species: Mouse PubMed
33 Pellegrini L et al. SIRT3 protects from hypoxia and staurosporine-mediated cell death by maintaining mitochondrial membrane potential and intracellular pH. Cell Death Differ 2012 May;
Pellegrini L et al
2012/01/01
Applications: WB, Species: Human PubMed
34 Muriel L坦pez C et al. Predictive factors for response to treatment in patients with advanced renal cell carcinoma. Invest New Drugs 2012 May;
Muriel L坦pez C et al
2012/01/01
Applications: IHC, Species: Human PubMed
35 Weber DC et al. The prognostic value of expression of HIF1α, EGFR and VEGF-A, in localized prostate cancer for intermediate- and high-risk patients treated with radiation therapy with or without androgen deprivation therapy. Radiat Oncol 2012;7:66
Weber DC et al
2012/01/01
Species: Human, Applications: IHC PubMed
36 Eguchi D et al. Hypoxia enhances the interaction between pancreatic stellate cells and cancer cells via increased secretion of connective tissue growth factor. J Surg Res 2012 Jul;
Eguchi D et al
2012/01/01
Species: Human, Applications: IHC PubMed
37 Brouillet S et al. EG-VEGF controls placental growth and survival in normal and pathological pregnancies: case of fetal growth restriction (FGR). Cell. Mol. Life Sci. 2012 Sep;
Brouillet S et al
2012/01/01
Species: Human, Applications: IHC PubMed
38 Fromy B et al. Asic3 is a neuronal mechanosensor for pressure-induced vasodilation that protects against pressure ulcers. Nat Med 2012 Jul;
Fromy B et al
2012/01/01
Species: Mouse, Applications: IHC PubMed
39 Engler JR et al. Increased microglia/macrophage gene expression in a subset of adult and pediatric astrocytomas. PLoS ONE 2012;7(8):e43339
Engler JR et al
2012/01/01
Species: Human, Applications: IHC PubMed
40 Piao Y et al. Glioblastoma resistance to anti-VEGF therapy is associated with myeloid cell infiltration, stem cell accumulation, and a mesenchymal phenotype. Neuro-oncology 2012 Nov;14(11):1379-92
Piao Y et al
2012/01/01
Applications: IHC PubMed
41 Muriel L坦pez C et al. Prognostic factors in patients with advanced renal cell carcinoma. Clin Genitourin Cancer 2012 Dec;10(4):262-70
Muriel L坦pez C et al
2012/01/01
Applications: IHC PubMed
42 Currie MJ et al. Immunohistochemical analysis of cancer stem cell markers in invasive breast carcinoma and associated ductal carcinoma in situ: relationships with markers of tumor hypoxia and microvascularity. Hum. Pathol. 2012 Oct;
Currie MJ et al
2012/01/01
Species: Human, Applications: IHC PubMed
43 Proescholdt MA et al. Function of carbonic anhydrase IX in glioblastoma multiforme. Neuro-oncology 2012 Nov;14(11):1357-66
Proescholdt MA et al
2012/01/01
Species: Human, Applications: IHC, WB PubMed
44 Pinato DJ et al. Immunohistochemical markers of the hypoxic response can identify malignancy in phaeochromocytomas and paragangliomas and optimize the detection of tumours with VHL germline mutations. Br. J. Cancer 2013 Feb;108(2):429-37
Pinato DJ et al
2013/01/01
Species: Human, Applications: IHC PubMed
45 Zhang Q et al. Wnt/β-catenin signaling enhances hypoxia-induced epithelial-mesenchymal transition in hepatocellular carcinoma via crosstalk with hif-1α signaling. Carcinogenesis 2013 Mar;
Zhang Q et al
2013/01/01
Species: Human, Applications: WB PubMed
46 Yin S et al. Arylsulfonamide KCN1 inhibits in vivo glioma growth and interferes with HIF signaling by disrupting HIF-1α interaction with cofactors p300/CBP. Clin. Cancer Res. 2012 Dec;18(24):6623-33
Yin S et al
2012/01/01
Species: Human, Applications: WB PubMed
47 Kato Y et al. Expression of a hypoxia-associated protein, carbonic anhydrase-9, correlates with malignant phenotypes of gastric carcinoma. Digestion 2010;82(4):246-51
Kato Y et al
2010/01/01
Species: Human, Applications: IHC PubMed
48 Aarntzen EH et al. Targeting of 111In-Labeled Dendritic Cell Human Vaccines Improved by Reducing Number of Cells. Clin. Cancer Res. 2013 Mar;19(6):1525-1533
Aarntzen EH et al
2013/01/01
Species: Human, Applications: IHC PubMed
49 Delhaas T et al. Steep increase in myonuclear domain size during infancy. Anat Rec (Hoboken) 2013 Feb;296(2):192-7
Delhaas T et al
2013/01/01
Species: Human, Applications: IHC, ICC/IF PubMed
50 Arvidsson Y et al. Hypoxia stimulates CXCR4 signalling in ileal carcinoids. Endocr. Relat. Cancer 2010 Jun;17(2):303-16
Arvidsson Y et al
2010/01/01
Species: Human, Applications: IHC PubMed
51 Cho SY et al. Activation of AMP-Activated Protein Kinase α and Extracelluar Signal-Regulated Kinase Mediates CB-PIC-Induced Apoptosis in Hypoxic SW620 Colorectal Cancer Cells. Evid Based Complement Alternat Med 2013;2013:974313
Cho SY et al
2013/01/01
Species: Human, Applications: IHC-P PubMed
52 Li Y et al. Antibody-specific detection of CAIX in breast and prostate cancers. Biochem. Biophys. Res. Commun. 2009 Aug;386(3):488-92
Li Y et al
2009/01/01
Species: Human, Applications: IHC-P PubMed
53 Carbonell WS et al. β1 integrin targeting potentiates antiangiogenic therapy and inhibits the growth of bevacizumab-resistant glioblastoma. Cancer Res. 2013 May;73(10):3145-54
Carbonell WS et al
2013/01/01
Species: Human, Applications: IHC-P, ICC/IF PubMed
54 Gauter-Fleckenstein B et al. Comparison of two Mn porphyrin-based mimics of superoxide dismutase in pulmonary radioprotection. Free Radic. Biol. Med. 2008 Mar;44(6):982-9
Gauter-Fleckenstein B et al
2008/01/01
Species: Rat, Applications: IHC-P PubMed
55 Bussolati B et al. Renal CD133+/CD73+ Progenitors Produce Erythropoietin under Hypoxia and Prolyl Hydroxylase Inhibition. J. Am. Soc. Nephrol. 2013 Jul;24(8):1234-41
Bussolati B et al
2013/01/01
PubMed
56 Baia GS et al. An orthotopic skull base model of malignant meningioma. Brain Pathol. 2008 Apr;18(2):172-9
Baia GS et al
2008/01/01
Species: Mouse, Applications: IHC-P PubMed
57 Park I et al. Evaluation of heterogeneous metabolic profile in an orthotopic human glioblastoma xenograft model using compressed sensing hyperpolarized 3D 13C magnetic resonance spectroscopic imaging. Magn Reson Med 2013 Jul;70(1):33-9
Park I et al
2013/01/01
Species: Rat, Applications: IHC-P PubMed
58 Dubois L et al. Targeting carbonic anhydrase IX by nitroimidazole based sulfamides enhances the therapeutic effect of tumor irradiation: A new concept of dual targeting drugs. Radiother Oncol 2013 Jul;
Dubois L et al
2013/01/01
Species: Mouse, Applications: IHC-Fr PubMed
59 Kumar S et al. Tumor dynamics in response to antiangiogenic therapy with oral metronomic topotecan and pazopanib in neuroblastoma xenografts. Transl Oncol 2013 Aug;6(4):493-503
Kumar S et al
2013/01/01
Species: Human, Applications: IHC PubMed
60 Pistollato F et al. Interaction of hypoxia-inducible factor-1α and Notch signaling regulates medulloblastoma precursor proliferation and fate. Stem Cells 2010 Nov;28(11):1918-29
Pistollato F et al
2010/01/01
Species: Human, Applications: IHC-P PubMed
61 Pistollato F et al. Intratumoral hypoxic gradient drives stem cells distribution and MGMT expression in glioblastoma. Stem Cells 2010 May;28(5):851-62
Pistollato F et al
2010/01/01
Species: Human, Applications: IHC-P PubMed
62 Campanile C et al. Characterization of Different Osteosarcoma Phenotypes by PET Imaging in Preclinical Animal Models. J. Nucl. Med. 2013 Aug;54(8):1362-8
Campanile C et al
2013/01/01
PubMed
63 Albert S et al. Prognostic value of the chemokine receptor CXCR4 and epithelial-to-mesenchymal transition in patients with squamous cell carcinoma of the mobile tongue. Oral Oncol. 2012 Jul;
Albert S et al
2012/01/01
PubMed
64 Wen YA et al. Downregulation of PHLPP expression contributes to hypoxia-induced resistance to chemotherapy in colon cancer cells. Mol. Cell. Biol. 2013 Nov;33(22):4594-605
Wen YA et al
2013/01/01
Species: Human, Applications: WB PubMed
65 El-Heliebi A et al. Are morphological criteria sufficient for the identification of circulating tumor cells in renal cancer? J Transl Med 2013;11:214
El-Heliebi A et al
2013/01/01
Species: Human, Applications: ICC/IF PubMed
66 F辰hling M et al. Tubular von Hippel-Lindau knockout protects against rhabdomyolysis-induced AKI. J. Am. Soc. Nephrol. 2013 Nov;24(11):1806-19
F辰hling M et al
2013/01/01
PubMed
67 Cioffi S et al. Tbx1 regulates brain vascularization. Hum. Mol. Genet. 2014 Jan;23(1):78-89
Cioffi S et al
2014/01/01
Species: Mouse, Applications: IHC-Fr, ICC/IF PubMed
68 Zhang M et al. The use of porous scaffold as a tumor model. Int J Biomater 2013;2013:396056
Zhang M et al
2013/01/01
Species: Human, Applications: IHC PubMed
69 Pinato DJ et al. An expression signature of the angiogenic response in gastrointestinal neuroendocrine tumours: correlation with tumour phenotype and survival outcomes. Br. J. Cancer 2014 Jan;110(1):115-22
Pinato DJ et al
2014/01/01
PubMed
70 Motzer RJ et al. Investigation of novel circulating proteins, germ line single-nucleotide polymorphisms, and molecular tumor markers as potential efficacy biomarkers of first-line sunitinib therapy for advanced renal cell carcinoma. Cancer Chemother. Phar
Motzer RJ et al
2014/01/01
Species: Human, Applications: IHC-P PubMed
71 Santos CD et al. Effects of preset sequential administrations of sunitinib and everolimus on tumour differentiation in Caki-1 renal cell carcinoma. Br. J. Cancer 2015 Jan;112(1):86-94
Santos CD et al
2015/01/01
Species: Human, Applications: IHC-P PubMed
72 Sadlecki P et al. The role of Hypoxia-inducible factor-1 α , glucose transporter-1, (GLUT-1) and carbon anhydrase IX in endometrial cancer patients. Biomed Res Int 2014;2014:616850
Sadlecki P et al
2014/01/01
Species: Human, Applications: IHC-P PubMed
73 Kwon OJ et al. HIF-1α and CA-IX as predictors of locoregional control for determining the optimal treatment modality for early-stage laryngeal carcinoma. Head Neck 2014 Feb;
Kwon OJ et al
2014/01/01
Species: Human, Applications: IHC-P PubMed
74 Chen LQ et al. Assessment of carbonic anhydrase IX expression and extracellular pH in B-cell lymphoma cell line models. Leuk. Lymphoma 2014 Nov;:1-8
Chen LQ et al
2014/01/01
PubMed
75 Hwa JS et al. The prognostic value of immunohistochemical markers for oral tongue squamous cell carcinoma. Eur Arch Otorhinolaryngol 2014 Aug;
Hwa JS et al
2014/01/01
PubMed
76 Chen X et al. XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway. Nature 2014 Apr;508(7494):103-7
Chen X et al
2014/01/01
Species: Human, Applications: IHC-P PubMed
77 Kang HJ et al. Expression of carbonic anhydrase 9 is a novel prognostic marker in resectable hepatocellular carcinoma. Virchows Arch. 2015 Jan;
Kang HJ et al
2015/01/01
Species: Human, Applications: IHC-P PubMed
78 Lin XY et al. Expression and diagnostic implications of carbonic anhydrase IX in several tumours with predominantly clear cell morphology. Histopathology 2015 Apr;66(5):685-94
Lin XY et al
2015/01/01
Species: Human, Applications: IHC-P PubMed
79 Gellert LL et al. The diagnostic accuracy of percutaneous renal needle core biopsy and its potential impact on the clinical management of renal cortical neoplasms. Arch. Pathol. Lab. Med. 2014 Dec;138(12):1673-9
Gellert LL et al
2014/01/01
Species: Human, Applications: IHC-P PubMed
80 Lee HJ et al. Inhibition of vascular endothelial growth factor a and hypoxia-inducible factor 1α maximizes the effects of radiation in sarcoma mouse models through destruction of tumor vasculature. Int. J. Radiat. Oncol. Biol. Phys. 2015 Mar;91(3):6
Lee HJ et al
2015/01/01
PubMed
81 Janmohamed SR et al. Support for the hypoxia theory in the pathogenesis of infantile haemangioma. Clin. Exp. Dermatol. 2014 Dec;
Janmohamed SR et al
2014/01/01
Species: Human, Applications: IHC-P PubMed
82 Morifuji Y et al. Reoxygenation from chronic hypoxia promotes metastatic processes in pancreatic cancer through the Hedgehog signaling. Cancer Sci. 2014 Mar;105(3):324-33
Morifuji Y et al
2014/01/01
PubMed
83 Polaナгki R et al. Activity of the monocarboxylate transporter 1 inhibitor AZD3965 in small cell lung cancer. Clin. Cancer Res. 2014 Feb;20(4):926-37
Polaナгki R et al
2014/01/01
Applications: IHC PubMed
84 Cotroneo E et al. Iron homeostasis and pulmonary hypertension: iron deficiency leads to pulmonary vascular remodeling in the rat. Circ. Res. 2015 May;116(10):1680-90
Cotroneo E et al
2015/01/01
Species: Rat, Applications: IHC PubMed
85 Dulloo I et al. Hypoxia-inducible TAp73 supports tumorigenesis by regulating the angiogenic transcriptome. Nat. Cell Biol. 2015 Apr;17(4):511-23
Dulloo I et al
2015/01/01
Species: Human, Applications: IHC-P PubMed
86 Heijmen L et al. Monitoring the effects of bevacizumab beyond progression in a murine colorectal cancer model: a functional imaging approach. Invest New Drugs 2013 Jan;
Heijmen L et al
2013/01/01
Species: Mouse, Applications: IHC, ICC/IF PubMed
87 Heijmen L et al. Monitoring hypoxia and vasculature during bevacizumab treatment in a murine colorectal cancer model. Contrast Media Mol Imaging ;9(3):237-45
Heijmen L et al
Species: Human, Applications: IHC-Fr PubMed
88 Zhou GX et al. Quantification of carbonic anhydrase IX expression in serum and tissue of renal cell carcinoma patients using enzyme-linked immunosorbent assay: prognostic and diagnostic potentials. Urology 2010 Feb;75(2):257-61
Zhou GX et al
2010/01/01
Species: Human, Applications: ELISA PubMed
89 Kinoshita H et al. Diffuse-type gastric cancer cells switch their driver pathways from FGFR2 signaling to SDF1/CXCR4 axis in hypoxic tumor microenvironments. Carcinogenesis 2015 Dec;36(12):1511-20
Kinoshita H et al
2015/01/01
Species: Mouse, Applications: IHC-P PubMed
90 Ward C et al. Evaluation of carbonic anhydrase IX as a therapeutic target for inhibition of breast cancer invasion and metastasis using a series of in vitro breast cancer models. Oncotarget 2015 Sep;6(28):24856-70
Ward C et al
2015/01/01
PubMed
91 Hong YS et al. Carbonic anhydrase 9 is a predictive marker of survival benefit from lower dose of bevacizumab in patients with previously treated metastatic colorectal cancer. BMC Cancer 2009;9:246
Hong YS et al
2009/01/01
Species: Human, Applications: IHC PubMed
92 Skapa P et al. Carbonic anhydrase IX expression in clear cell renal cell carcinomas negatively correlates with the proportion of the granular cell component. J. Clin. Oncol. 2008 Aug;26(22):3809-11; author reply 3811-2
Skapa P et al
2008/01/01
Species: Human PubMed
93 Al-Ahmadie HA et al. Carbonic anhydrase IX expression in clear cell renal cell carcinoma: an immunohistochemical study comparing 2 antibodies. Am. J. Surg. Pathol. 2008 Mar;32(3):377-82
Al-Ahmadie HA et al
2008/01/01
Species: Human, Applications: IHC PubMed
94 Bachmann IM et al. Tumor necrosis is associated with increased alphavbeta3 integrin expression and poor prognosis in nodular cutaneous melanomas. BMC Cancer 2008;8:362
Bachmann IM et al
2008/01/01
Species: Human, Applications: IHC PubMed
95 O"Toole D et al. Molecular markers associated with response to chemotherapy in gastro-entero-pancreatic neuroendocrine tumors. Endocr. Relat. Cancer 2010 Dec;17(4):847-56
O"Toole D et al
2010/01/01
Species: Human, Applications: IHC PubMed
96 Yoon C et al. Hypoxia-activated chemotherapeutic TH-302 enhances the effects of VEGF-A inhibition and radiation on sarcomas. Br. J. Cancer 2015 Jun;113(1):46-56
Yoon C et al
2015/01/01
Species: Human, Applications: IHC-P, ICC/IF PubMed
97 Jamali S et al. Hypoxia-induced carbonic anhydrase IX facilitates lactate flux in human breast cancer cells by non-catalytic function. Sci Rep 2015;5:13605
Jamali S et al
2015/01/01
Species: Human, Applications: WB, ICC/IF PubMed
98 Nelson MP et al. IL-33 and M2a alveolar macrophages promote lung defense against the atypical fungal pathogen Pneumocystis murina. J. Immunol. 2011 Feb;186(4):2372-81
Nelson MP et al
2011/01/01
Applications: ChIP PubMed
99 Nakao M et al. Prognostic significance of carbonic anhydrase IX expression by cancer-associated fibroblasts in lung adenocarcinoma. Cancer 2009 Jun;115(12):2732-43
Nakao M et al
2009/01/01
Species: Human, Applications: WB PubMed
100 Eikrem O et al. Transcriptome Sequencing (RNAseq) Enables Utilization of Formalin-Fixed, Paraffin-Embedded Biopsies with Clear Cell Renal Cell Carcinoma for Exploration of Disease Biology and Biomarker Development. PLoS ONE 2016;11(2):e0149743
Eikrem O et al
2016/01/01
PubMed
101 Islam SS et al. Simultaneous Targeting of Bladder Tumor Growth, Survival, and Epithelial-to-Mesenchymal Transition with a Novel Therapeutic Combination of Acetazolamide (AZ) and Sulforaphane (SFN). Target Oncol 2016 Apr;11(2):209-27
Islam SS et al
2016/01/01
PubMed
102 Song CW et al. Indirect Tumor Cell Death After High-Dose Hypofractionated Irradiation: Implications for Stereotactic Body Radiation Therapy and Stereotactic Radiation Surgery. Int. J. Radiat. Oncol. Biol. Phys. 2015 Sep;93(1):166-72
Song CW et al
2015/01/01
PubMed
103 Andr辿 H et al. Hypoxia-Inducible Factor-1α Is Associated With Sprouting Angiogenesis in the Murine Laser-Induced Choroidal Neovascularization Model. Invest. Ophthalmol. Vis. Sci. 2015 Oct;56(11):6591-604
Andr辿 H et al
2015/01/01
PubMed
104 Badar T et al. Phase I study of evofosfamide, an investigational hypoxia-activated prodrug, in patients with advanced leukemia. Am. J. Hematol. 2016 Aug;91(8):800-5
Badar T et al
2016/01/01
PubMed
105 Scholz A et al. Endothelial cell-derived angiopoietin-2 is a therapeutic target in treatment-naive and bevacizumab-resistant glioblastoma. EMBO Mol Med 2016 Jan;8(1):39-57
Scholz A et al
2016/01/01
PubMed
106 Leek R et al. Methods: Using Three-Dimensional Culture (Spheroids) as an In Vitro Model of Tumour Hypoxia. Adv. Exp. Med. Biol. 2016;899:167-96
Leek R et al
2016/01/01
PubMed
107 Ono M et al. Enhanced snoMEN Vectors Facilitate Establishment of GFP-HIF-1α Protein Replacement Human Cell Lines. PLoS ONE 2016;11(4):e0154759
Ono M et al
2016/01/01
PubMed
108 Baine MK et al. Characterization of tumor infiltrating lymphocytes in paired primary and metastatic renal cell carcinoma specimens. Oncotarget 2015 Sep;6(28):24990-5002
Baine MK et al
2015/01/01
PubMed
109 Newton IP et al. Adenomatous polyposis coli and hypoxia-inducible factor-1{alpha} have an antagonistic connection. Mol. Biol. Cell 2010 Nov;21(21):3630-8
Newton IP et al
2010/01/01
PubMed
110 Mitsuhashi A et al. Fibrocyte-like cells mediate acquired resistance to anti-angiogenic therapy with bevacizumab. Nat Commun 2015;6:8792
Mitsuhashi A et al
2015/01/01
PubMed
111 He H et al. A Sensitive IHC Method for Monitoring Autophagy-Specific Markers in Human Tumor Xenografts. J Biomark 2016;2016:1274603
He H et al
2016/01/01
PubMed
112 Xu W et al. Increased mitochondrial arginine metabolism supports bioenergetics in asthma. J. Clin. Invest. 2016 Jul;126(7):2465-81
Xu W et al
2016/01/01
PubMed
113 Chaudary N et al. Characterization of the Tumor-Microenvironment in Patient-Derived Cervix Xenografts (OCICx). Cancers (Basel) 2012;4(3):821-45
Chaudary N et al
2012/01/01
PubMed
114 Park I et al. Hyperpolarized 13C magnetic resonance metabolic imaging: application to brain tumors. Neuro-oncology 2010 Feb;12(2):133-44
Park I et al
2010/01/01
PubMed
115 Hecht JL et al. Revisiting decidual vasculopathy. Placenta 2016 Jun;42:37-43
Hecht JL et al
2016/01/01
PubMed
116 Di Napoli A et al. Tissue biomarkers in renal cell carcinoma: issues and solutions. Cancer 2009 May;115(10 Suppl):2290-7
Di Napoli A et al
2009/01/01
PubMed
117 Dumais J. Plant morphogenesis: a role for mechanical signals. Curr. Biol. 2009 Mar;19(5):R207-8
Dumais J
2009/01/01
PubMed
118 Ferecatu I et al. Dysfunction in the mitochondrial Fe-S assembly machinery leads to formation of the chemoresistant truncated VDAC1 isoform without HIF-1α activation. PLoS ONE 2018;13(3):e0194782
Ferecatu I et al
2018/01/01
Species: Human, Applications: WB PubMed
119 Steenbrugge J et al. Anti-inflammatory signaling by mammary tumor cells mediates prometastatic macrophage polarization in an innovative intraductal mouse model for triple-negative breast cancer. J. Exp. Clin. Cancer Res. 2018 Aug;37(1):191
Steenbrugge J et al
2018/01/01
Species: Mouse, Applications: IHC-P PubMed
120 Young JR et al. Utility of multiphasic multidetector computed tomography in discriminating between clear cell renal cell carcinomas with high and low carbonic anhydrase-IX expression. Abdom Radiol (NY) 2018 Oct;43(10):2734-2742
Young JR et al
2018/01/01
Applications: IHC PubMed
121 Radoul M et al. MR Studies of Glioblastoma Models Treated with Dual PI3K/mTOR Inhibitor and Temozolomide:Metabolic Changes Are Associated with Enhanced Survival. Mol. Cancer Ther. 2016 05;15(5):1113-22
Radoul M et al
2016/01/01
Species: Mouse, Applications: IHC PubMed
122 Yoon C et al. Multimodal targeting of tumor vasculature and cancer stem-like cells in sarcomas with VEGF-A inhibition, HIF-1α inhibition, and hypoxia-activated chemotherapy. Oncotarget 2016 Jul;7(28):42844-42858
Yoon C et al
2016/01/01
Species: Mouse PubMed
123 Guo J et al. Hypoxia suppresses cylindromatosis (CYLD) expression to promote inflammation in glioblastoma: possible link to acquired resistance to anti-VEGF therapy. Oncotarget 2014 Aug;5(15):6353-64
Guo J et al
2014/01/01
Species: Human, Applications: IHC PubMed
124 Balasundaram G et al. Noninvasive Anatomical and Functional Imaging of Orthotopic Glioblastoma Development and Therapy using Multispectral Optoacoustic Tomography. Transl Oncol 2018 Oct;11(5):1251-1258
Balasundaram G et al
2018/01/01
Species: Mouse, Applications: IHC-P PubMed
125 Rosenberg T et al. Heterogenic expression of stem cell markers in patient-derived glioblastoma spheroid cultures exposed to long-term hypoxia. CNS Oncol 2018 Apr;7(2):CNS15
Rosenberg T et al
2018/01/01
Species: Human, Applications: IHC PubMed
126 Eikrem OS et al. Development and confirmation of potential gene classifiers of human clear cell renal cell carcinoma using next-generation RNA sequencing. Scand J Urol 2016 Dec;50(6):452-462
Eikrem OS et al
2016/01/01
Species: Human, Applications: IHC PubMed
127 Kim EN et al. A Pyloric Gland-Phenotype Ovarian Mucinous Tumor Resembling Lobular Endocervical Glandular Hyperplasia in a Patient with Peutz-Jeghers Syndrome. J Pathol Transl Med 2017 Mar;51(2):159-164
Kim EN et al
2017/01/01
Applications: IHC-P PubMed
128 Davis RM et al. Surface-Enhanced Raman Scattering Nanoparticles for Multiplexed Imaging of Bladder Cancer Tissue Permeability and Molecular Phenotype. ACS Nano 2018 Oct;12(10):9669-9679
Davis RM et al
2018/01/01
Species: Human, Applications: ICC/IF PubMed
129 Corbet C et al. Interruption of lactate uptake by inhibiting mitochondrial pyruvate transport unravels direct antitumor and radiosensitizing effects. Nat Commun 2018 03;9(1):1208
Corbet C et al
2018/01/01
Species: Human, Applications: IHC PubMed
130 Bulusu V et al. Acetate Recapturing by Nuclear Acetyl-CoA Synthetase 2 Prevents Loss of Histone Acetylation during Oxygen and Serum Limitation. Cell Rep 2017 01;18(3):647-658
Bulusu V et al
2017/01/01
Species: Human, Applications: IHC PubMed
131 Wang D et al. BIRC3 is a biomarker of mesenchymal habitat of glioblastoma, and a mediator of survival adaptation in hypoxia-driven glioblastoma habitats. Sci Rep 2017 Aug;7(1):9350
Wang D et al
2017/01/01
Species: Mouse, Applications: WB PubMed
132 Dreyer-Andersen N et al. Intermittent, low dose carbon monoxide exposure enhances survival and dopaminergic differentiation of human neural stem cells. PLoS ONE 2018;13(1):e0191207
Dreyer-Andersen N et al
2018/01/01
Species: Human, Applications: ICC/IF PubMed
133 Tsuji T et al. Dissecting the Process of Activation of Cancer-promoting Zinc-requiring Ectoenzymes by Zinc Metalation Mediated by ZNT Transporters. J. Biol. Chem. 2017 02;292(6):2159-2173
Tsuji T et al
2017/01/01
WB PubMed
134 Li Y et al. Expression and activity of carbonic anhydrase IX is associated with metabolic dysfunction in MDA-MB-231 breast cancer cells. Cancer Invest. 2009 Jul;27(6):613-23
Li Y et al
2009/01/01
Species: Human, Applications: WB PubMed
135 Meijer TW et al. Tumor microenvironmental changes induced by the sulfamate carbonic anhydrase IX inhibitor S4 in a laryngeal tumor model. PLoS ONE 2014;9(9):e108068
Meijer TW et al
2014/01/01
Species: Mouse, Applications: IHC PubMed
136 Ames S et al. The proteoglycan-like domain of carbonic anhydrase IX mediates non-catalytic facilitation of lactate transport in cancer cells. Oncotarget 2018 Jun;9(46):27940-27957
Ames S et al
2018/01/01
Species: Human, Applications: WB PubMed
137 Bucau M et al. 18F-FDG Uptake in Well-Differentiated Neuroendocrine Tumors Correlates with Both Ki-67 and VHL Pathway Inactivation. Neuroendocrinology 2018;106(3):274-282
Bucau M et al
2018/01/01
Species: Human, Applications: PubMed
138 Hirakawa T et al. Pancreatic Fibroblasts Stimulate the Motility of Pancreatic Cancer Cells through IGF1/IGF1R Signaling under Hypoxia. PLoS ONE 2016;11(8):e0159912
Hirakawa T et al
2016/01/01
Species: Human, Applications: IHC PubMed
139 Zhang Y et al. Maintenance of antiangiogenic and antitumor effects by orally active low-dose capecitabine for long-term cancer therapy. Proc. Natl. Acad. Sci. U.S.A. 2017 06;114(26):E5226-E5235
Zhang Y et al
2017/01/01
PubMed
140 Nakamura M et al. Off-tumor targets compromise antiangiogenic drug sensitivity by inducing kidney erythropoietin production. Proc. Natl. Acad. Sci. U.S.A. 2017 11;114(45):E9635-E9644
Nakamura M et al
2017/01/01
Species: Mouse, Applications: PubMed
141 Bousquet G et al. Targeting autophagic cancer stem-cells to reverse chemoresistance in human triple negative breast cancer. Oncotarget 2017 May;8(21):35205-35221
Bousquet G et al
2017/01/01
Species: Human, Applications: ICC/IF PubMed
142 Frost J et al. Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition. Nat Commun 2016 11;7:13312
Frost J et al
2016/01/01
WB PubMed
143 Boyd NH et al. Addition of carbonic anhydrase 9 inhibitor SLC-0111 to temozolomide treatment delays glioblastoma growth in vivo. JCI Insight 2017 Dec;2(24)
Boyd NH et al
2017/01/01
Species: Human, Applications: WB PubMed
144 Burman A et al. Localized hypoxia links ER stress to lung fibrosis through induction of C/EBP homologous protein. JCI Insight 2018 Aug;3(16)
Burman A et al
2018/01/01
Species: Mouse, Applications: IHC-P PubMed
145 Brossa A et al. Sunitinib but not VEGF blockade inhibits cancer stem cell endothelial differentiation. Oncotarget 2015 May;6(13):11295-309
Brossa A et al
2015/01/01
Species: Mouse, Applications: IHC, ICC/IF PubMed
146 Fraga A et al. Genetic polymorphisms in key hypoxia-regulated downstream molecules and phenotypic correlation in prostate cancer. BMC Urol 2017 Jan;17(1):12
Fraga A et al
2017/01/01
Species: Human, Applications: PubMed
147 Kasashima H et al. Lysyl oxidase is associated with the epithelial-mesenchymal transition of gastric cancer cells in hypoxia. Gastric Cancer 2016 Apr;19(2):431-42
Kasashima H et al
2016/01/01
PubMed
148 Dachs GU et al. A profile of prognostic and molecular factors in European and Māori breast cancer patients. BMC Cancer 2010 Oct;10:543
Dachs GU et al
2010/01/01
Species: Human, Applications: IHC PubMed
149 Tudisco L et al. Hypoxia activates placental growth factor expression in lymphatic endothelial cells. Oncotarget 2017 May;8(20):32873-32883
Tudisco L et al
2017/01/01
Species: Mouse, Applications: IHC PubMed
150 Faes S et al. Targeting carbonic anhydrase IX improves the anti-cancer efficacy of mTOR inhibitors. Oncotarget 2016 Jun;7(24):36666-36680
Faes S et al
2016/01/01
Species: Mouse, Applications: IHC PubMed
151 Huang Y et al. Antitumor and Antiangiogenic Effects of Aspirin-PC in Ovarian Cancer. Mol. Cancer Ther. 2016 Dec;15(12):2894-2904
Huang Y et al
2016/01/01
Species: Human, Applications: IHC PubMed
152 van Kuijk SJ et al. The Sulfamate Small Molecule CAIX Inhibitor S4 Modulates Doxorubicin Efficacy. PLoS ONE 2016;11(8):e0161040
van Kuijk SJ et al
2016/01/01
Species: Human, Applications: IHC PubMed
153 Stillebroer AB et al. Carbonic anhydrase IX in renal cell carcinoma: implications for prognosis, diagnosis, and therapy. Eur. Urol. 2010 Jul;58(1):75-83
Stillebroer AB et al
2010/01/01
PubMed
154 Himmels P et al. Motor neurons control blood vessel patterning in the developing spinal cord. Nat Commun 2017 Mar;8:14583
Himmels P et al
2017/01/01
Species: Mouse, Applications: IHC-FR PubMed
155 Klameth L et al. Small cell lung cancer: model of circulating tumor cell tumorospheres in chemoresistance. Sci Rep 2017 Jul;7(1):5337
Klameth L et al
2017/01/01
Species: Human, Applications: IHC-P PubMed
156 Cauchy F et al. Strong antineoplastic effects of metformin in preclinical models of liver carcinogenesis. Clin. Sci. 2017 01;131(1):27-36
Cauchy F et al
2017/01/01
PubMed
157 Lambrechts D et al. Phenotype molding of stromal cells in the lung tumor microenvironment. Nat. Med. 2018 Aug;24(8):1277-1289
Lambrechts D et al
2018/01/01
Species: Human, Applications: IHC-P PubMed
158 Mudie S et al. PITX1, a specificity determinant in the HIF-1α-mediated transcriptional response to hypoxia. Cell Cycle 2014;13(24):3878-91
Mudie S et al
2014/01/01
WB PubMed
159 Klier M et al. Catalytic activity of human carbonic anhydrase isoform IX is displayed both extra- and intracellularly. FEBS J. 2016 Jan;283(1):191-200
Klier M et al
2016/01/01
PubMed
160 Greenhough A et al. Cancer cell adaptation to hypoxia involves a HIF-GPRC5A-YAP axis. EMBO Mol Med 2018 Nov;10(11)
Greenhough A et al
2018/01/01
Species: Human, Applications: WB PubMed
161 Takenaka M et al. Iron regulatory protein 2 in ovarian endometrial cysts. Biochem. Biophys. Res. Commun. 2017 Jun;487(4):789-794
Takenaka M et al
2017/01/01
PubMed
162 Iwamoto H et al. Cancer Lipid Metabolism Confers Antiangiogenic Drug Resistance. Cell Metab. 2018 Jul;28(1):104-117.e5
Iwamoto H et al
2018/01/01
ICC/IF PubMed
163 Oh ET et al. NQO1 inhibits proteasome-mediated degradation of HIF-1α. Nat Commun 2016 Dec;7:13593
Oh ET et al
2016/01/01
Species: Mouse, Applications: IHC PubMed
164 He L et al. Antiangiogenic effects of recombinant human endostatin in lung cancers. Mol Med Rep 2018 Jan;17(1):79-86
He L et al
2018/01/01
Species: Mouse, Applications: PubMed
165 Toonen LJA et al. Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model. Mol Neurodegener 2018 06;13(1):31
Toonen LJA et al
2018/01/01
PubMed
166 Kennedy JM et al. Clinical and morphologic review of 60 hereditary renal tumors from 30 hereditary renal cell carcinoma syndrome patients: lessons from a contemporary single institution series. Med Oncol 2019 Jul;36(9):74
Kennedy JM et al
2019/01/01
PubMed
167 Pinato DJ et al. Programmed cell death ligands expression in phaeochromocytomas and paragangliomas: Relationship with the hypoxic response, immune evasion and malignant behavior. Oncoimmunology ;6(11):e1358332
Pinato DJ et al
PubMed
168 Steenbrugge J et al. Comparative Profiling of Metastatic 4T1- vs. Non-metastatic Py230-Based Mammary Tumors in an Intraductal Model for Triple-Negative Breast Cancer. Front Immunol 2019;10:2928
Steenbrugge J et al
2019/01/01
PubMed
169 Ghosh P et al. Oxygen-Enhanced Optoacoustic Tomography Reveals the Effectiveness of Targeting Heme and Oxidative Phosphorylation at Normalizing Tumor Vascular Oxygenation. Cancer Res 2020 09;80(17):3542-3555
Ghosh P et al
2020/01/01
PubMed
170 M辿hes G et al. Carbonic Anhydrase Inhibitor Acetazolamide Enhances CHOP Treatment Response and Stimulates Effector T-Cell Infiltration in A20/BalbC Murine B-Cell Lymphoma. Int J Mol Sci 2020 Jul;21(14)
M辿hes G et al
2020/01/01
PubMed
171 Becker LM et al. Epigenetic Reprogramming of Cancer-Associated Fibroblasts Deregulates Glucose Metabolism and Facilitates Progression of Breast Cancer. Cell Rep 2020 06;31(9):107701
Becker LM et al
2020/01/01
PubMed
172 Matolay O et al. Quantitative Analysis of Carbonic Anhydrase IX Uncovers Hypoxia-Related Functional Differences in Classical Hodgkin Lymphoma Subtypes. Int J Mol Sci 2019 Jul;20(14)
Matolay O et al
2019/01/01
PubMed
173 Abdulfatah E et al. Clinicopathological characterisation of renal cell carcinoma in young adults: a contemporary update and review of literature. Histopathology 2020 May;76(6):875-887
Abdulfatah E et al
2020/01/01
PubMed
174 Lovisa S et al. Endothelial-to-mesenchymal transition compromises vascular integrity to induce Myc-mediated metabolic reprogramming in kidney fibrosis. Sci Signal 2020 06;13(635)
Lovisa S et al
2020/01/01
PubMed
175 Recondo G et al. Diverse Resistance Mechanisms to the Third-Generation ALK Inhibitor Lorlatinib in ALK-Rearranged Lung Cancer. Clin Cancer Res 2020 01;26(1):242-255
Recondo G et al
2020/01/01
PubMed
176 Brown E et al. Mucosal inflammation downregulates PHD1 expression promoting a barrier-protective HIF-1α response in ulcerative colitis patients. FASEB J 2020 03;34(3):3732-3742
Brown E et al
2020/01/01
PubMed
177 Fu SY et al. Sunitinib Treatment-elicited Distinct Tumor Microenvironment Dramatically Compensated the Reduction of Myeloid-derived Suppressor Cells. In Vivo ;34(3):1141-1152
Fu SY et al
PubMed
178 Kikuchi H et al. Chemotherapy-Induced IL8 Upregulates MDR1/ABCB1 in Tumor Blood Vessels and Results in Unfavorable Outcome. Cancer Res 2020 07;80(14):2996-3008
Kikuchi H et al
2020/01/01
PubMed
179 Chen S et al. Eradication of tumor growth by delivering novel photothermal selenium-coated tellurium nanoheterojunctions. Sci Adv 2020 04;6(15):eaay6825
Chen S et al
2020/01/01
PubMed
180 Hosaka K et al. Therapeutic paradigm of dual targeting VEGF and PDGF for effectively treating FGF-2 off-target tumors. Nat Commun 2020 07;11(1):3704
Hosaka K et al
2020/01/01
PubMed
181 Ortmann B et al. CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells. J. Cell. Sci. 2016 Jan;129(1):191-205
Ortmann B et al
2016/01/01
PubMed
182 Xiao Y et al. S100A10 Is a Critical Mediator of GAS6/AXL-Induced Angiogenesis in Renal Cell Carcinoma. Cancer Res 2019 11;79(22):5758-5768
Xiao Y et al
2019/01/01
PubMed
183 Kuthi L et al. Clinicopathological Findings on 28 Cases with XP11.2 Renal Cell Carcinoma. Pathol Oncol Res 2020 Oct;26(4):2123-2133
Kuthi L et al
2020/01/01
PubMed
184 Kim M et al. Comprehensive Immunoprofiles of Renal Cell Carcinoma Subtypes. Cancers (Basel) 2020 Mar;12(3)
Kim M et al
2020/01/01
PubMed
185 Mikkelsen ML et al. Surgically induced ischemia has no impact on protein expression levels of HIF-1α and related biomarkers in renal cell carcinoma. APMIS 2021 Sep;129(9):535-547
Mikkelsen ML et al
2021/01/01
PubMed
186 Anemone A et al. Tumour acidosis evaluated in vivo by MRI-CEST pH imaging reveals breast cancer metastatic potential. Br J Cancer 2021 01;124(1):207-216
Anemone A et al
2021/01/01
PubMed
187 Alberti D et al. In vitro and in vivo BNCT investigations using a carborane containing sulfonamide targeting CAIX epitopes on malignant pleural mesothelioma and breast cancer cells. Sci Rep 2020 11;10(1):19274
Alberti D et al
2020/01/01
PubMed
188 Dong Y et al. Tumor Xenografts of Human Clear Cell Renal Cell Carcinoma But Not Corresponding Cell Lines Recapitulate Clinical Response to Sunitinib: Feasibility of Using Biopsy Samples. Eur Urol Focus 2017 12;3(6):590-598
Dong Y et al
2017/01/01
PubMed
189 Steenbrugge J et al. OMO-1 reduces progression and enhances cisplatin efficacy in a 4T1-based non-c-MET addicted intraductal mouse model for triple-negative breast cancer. NPJ Breast Cancer 2021 Mar;7(1):27
Steenbrugge J et al
2021/01/01
PubMed
190 Mehibel M et al. Eliminating hypoxic tumor cells improves response to PARP inhibitors in homologous recombination-deficient cancer models. J Clin Invest 2021 Jun;131(11)
Mehibel M et al
2021/01/01
PubMed
191 Gillen AE et al. Single-Cell RNA Sequencing of Childhood Ependymoma Reveals Neoplastic Cell Subpopulations That Impact Molecular Classification and Etiology. Cell Rep 2020 08;32(6):108023
Gillen AE et al
2020/01/01
PubMed
192 Simko V et al. PIMT Binding to C-Terminal Ala459 of CAIX Is Involved in Inside-Out Signaling Necessary for Its Catalytic Activity. Int J Mol Sci 2020 Nov;21(22)
Simko V et al
2020/01/01
PubMed
193 Menga A et al. Glufosinate constrains synchronous and metachronous metastasis by promoting anti-tumor macrophages. EMBO Mol Med 2020 10;12(10):e11210
Menga A et al
2020/01/01
PubMed
194 Lin C et al. Fenofibrate inhibits hypoxia-inducible factor-1 alpha and carbonic anhydrase expression through activation of AMP-activated protein kinase/HO-1/Sirt1 pathway in glioblastoma cells. Environ Toxicol 2021 Dec;36(12):2551-2561
Lin C et al
2021/01/01
PubMed
195 Pang L et al. Plasmacytoid dendritic cells recruited by HIF-1α/eADO/ADORA1 signaling induce immunosuppression in hepatocellular carcinoma. Cancer Lett 2021 Dec;522:80-92
Pang L et al
2021/01/01
Species: Human, Applications: IHC PubMed
196 Wang Y et al. Histone citrullination by PADI4 is required for HIF-dependent transcriptional responses to hypoxia and tumor vascularization. Sci Adv 2021 Aug;7(35)
Wang Y et al
2021/01/01
Species: Human, Applications: IHC PubMed
  • No.: 1
  • 文献情報:
    Yoo H et al. Expression of the hypoxia marker carbonic anhydrase 9 is associated with anaplastic phenotypes in meningiomas. Clin. Cancer Res. 2007 Jan;13(1):68-75
    Yoo H et al
    2007/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 2
  • 文献情報:
    Westbury CB et al. Hypoxia can be detected in irradiated normal human tissue: a study using the hypoxic marker pimonidazole hydrochloride. Br J Radiol 2007 Nov;80(959):934-8
    Westbury CB et al
    2007/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 3
  • 文献情報:
    Kaidi A et al. Is the downregulation of EphB2 receptor expression during colorectal tumorigenesis due to hypoxia? Gut 2007 Nov;56(11):1637-8
    Kaidi A et al
    2007/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 4
  • 文献情報:
    Sathornsumetee S et al. Tumor angiogenic and hypoxic profiles predict radiographic response and survival in malignant astrocytoma patients treated with bevacizumab and irinotecan. J. Clin. Oncol. 2008 Jan;26(2):271-8
    Sathornsumetee S et al
    2008/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 5
  • 文献情報:
    Van den Eynden GG et al. Angiogenesis and hypoxia in lymph node metastases is predicted by the angiogenesis and hypoxia in the primary tumour in patients with breast cancer. Br. J. Cancer 2005 Nov;93(10):1128-36
    Van den Eynden GG et al
    2005/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 6
  • 文献情報:
    Lapinski JE et al. Distinguishing clear cell renal cell carcinoma, retroperitoneal paraganglioma, and adrenal cortical lesions on limited biopsy material: utility of immunohistochemical markers. Appl. Immunohistochem. Mol. Morphol. 2010 Oct;18(5):414-21
    Lapinski JE et al
    2010/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 7
  • 文献情報:
    M端ller J. [Recent evaluation of a Candida hemagglutination test]. Mycoses 1991;34 Suppl 1:63-7
    M端ller J
    1991/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 8
  • 文献情報:
    Gabai VL et al. Heat shock transcription factor Hsf1 is involved in tumor progression via regulation of hypoxia-inducible factor 1 and RNA-binding protein HuR. Mol. Cell. Biol. 2012 Mar;32(5):929-40
    Gabai VL et al
    2012/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 9
  • 文献情報:
    Ogino T et al. Inclusive estimation of complex antigen presentation functions of monocyte-derived dendritic cells differentiated under normoxia and hypoxia conditions. Cancer Immunol. Immunother. 2012 Mar;61(3):409-24
    Ogino T et al
    2012/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 10
  • 文献情報:
    Garcia-Parra R et al. Investigation on tumor hypoxia in resectable primary prostate cancer as demonstrated by 18F-FAZA PET/CT utilizing multimodality fusion techniques. Eur. J. Nucl. Med. Mol. Imaging 2011 Oct;38(10):1816-23
    Garcia-Parra R et al
    2011/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 11
  • 文献情報:
    Li Y et al. Role of hypoxia and EGF on expression, activity, localization and phosphorylation of carbonic anhydrase IX in MDA-MB-231 breast cancer cells. Biochim. Biophys. Acta 2011 Jan;1813(1):159-67
    Li Y et al
    2011/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 12
  • 文献情報:
    Sakata K et al. Brachytherapy for oral tongue cancer: an analysis of treatment results with various biological markers. Jpn. J. Clin. Oncol. 2008 Jun;38(6):402-7
    Sakata K et al
    2008/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 13
  • 文献情報:
    Wang Y et al. Hypoxia promotes ligand-independent EGF receptor signaling via hypoxia-inducible factor-mediated upregulation of caveolin-1. Proc. Natl. Acad. Sci. U.S.A. 2012 Mar;109(13):4892-7
    Wang Y et al
    2012/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 14
  • 文献情報:
    Chamboredon S et al. Hypoxia-inducible factor-1α mRNA: a new target for destabilization by tristetraprolin in endothelial cells. Mol. Biol. Cell 2011 Sep;22(18):3366-78
    Chamboredon S et al
    2011/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 15
  • 文献情報:
    Chaumeil MM et al. Hyperpolarized 13C MR spectroscopic imaging can be used to monitor Everolimus treatment in vivo in an orthotopic rodent model of glioblastoma. Neuroimage 2012 Jan;59(1):193-201
    Chaumeil MM et al
    2012/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 16
  • 文献情報:
    Al-Ahmadie HA et al. Role of immunohistochemistry in the evaluation of needle core biopsies in adult renal cortical tumors: an ex vivo study. Am. J. Surg. Pathol. 2011 Jul;35(7):949-61
    Al-Ahmadie HA et al
    2011/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 17
  • 文献情報:
    Lucio-Eterovic AK et al. Mediators of glioblastoma resistance and invasion during antivascular endothelial growth factor therapy. Clin. Cancer Res. 2009 Jul;15(14):4589-99
    Lucio-Eterovic AK et al
    2009/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 18
  • 文献情報:
    Loinard C et al. Inhibition of prolyl hydroxylase domain proteins promotes therapeutic revascularization. Circulation 2009 Jul;120(1):50-9
    Loinard C et al
    2009/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 19
  • 文献情報:
    Atkins M et al. Carbonic anhydrase IX expression predicts outcome of interleukin 2 therapy for renal cancer. Clin. Cancer Res. 2005 May;11(10):3714-21
    Atkins M et al
    2005/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 20
  • 文献情報:
    Guise CP et al. Diflavin oxidoreductases activate the bioreductive prodrug PR-104A under hypoxia. Mol. Pharmacol. 2012 Jan;81(1):31-40
    Guise CP et al
    2012/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 21
  • 文献情報:
    Chen J et al. Hypoxia-mediated up-regulation of Pim-1 contributes to solid tumor formation. Am. J. Pathol. 2009 Jul;175(1):400-11
    Chen J et al
    2009/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 22
  • 文献情報:
    Benito J et al. Pronounced hypoxia in models of murine and human leukemia: high efficacy of hypoxia-activated prodrug PR-104. PLoS ONE 2011;6(8):e23108
    Benito J et al
    2011/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 23
  • 文献情報:
    Ba単uelos CA et al. gammaH2AX expression in tumors exposed to cisplatin and fractionated irradiation. Clin. Cancer Res. 2009 May;15(10):3344-53
    Ba単uelos CA et al
    2009/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 24
  • 文献情報:
    Melvin A et al. The chromatin remodeler ISWI regulates the cellular response to hypoxia: role of FIH. Mol. Biol. Cell 2011 Nov;22(21):4171-81
    Melvin A et al
    2011/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 25
  • 文献情報:
    Narita T et al. Identification of a novel small molecule HIF-1alpha translation inhibitor. Clin. Cancer Res. 2009 Oct;15(19):6128-36
    Narita T et al
    2009/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 26
  • 文献情報:
    Mackenzie KA et al. Angiogenesis and host immune response contribute to the aggressive character of non-melanoma skin cancers in renal transplant recipients. Histopathology 2011 May;58(6):875-85
    Mackenzie KA et al
    2011/01/01
  • 備考:
    Applications: IHC, Species: Human
  • 参照:
    PubMed
  • No.: 27
  • 文献情報:
    Jung JH et al. Lowered expression of galectin-2 is associated with lymph node metastasis in gastric cancer. J. Gastroenterol. 2012 Jan;47(1):37-48
    Jung JH et al
    2012/01/01
  • 備考:
    Applications: WB, Species: Human
  • 参照:
    PubMed
  • No.: 28
  • 文献情報:
    Deschamps L et al. The expression of the hypoxia markers CA9 and CXCR4 is correlated with survival in patients with neuroendocrine tumours of the ileum. Neuroendocrinology 2012;95(3):214-22
    Deschamps L et al
    2012/01/01
  • 備考:
    Applications: IHC, Species: Human
  • 参照:
    PubMed
  • No.: 29
  • 文献情報:
    Lim CS et al. Increased activation of the hypoxia-inducible factor pathway in varicose veins. J. Vasc. Surg. 2012 May;55(5):1427-39
    Lim CS et al
    2012/01/01
  • 備考:
    Applications: WB, Species: Human
  • 参照:
    PubMed
  • No.: 30
  • 文献情報:
    Matsumura Y et al. Morphophenotypic characteristics of intralymphatic cancer and stromal cells susceptible to lymphogenic metastasis. Cancer Sci 2012 Mar;
    Matsumura Y et al
    2012/01/01
  • 備考:
    Applications: IHC, Species: Human
  • 参照:
    PubMed
  • No.: 31
  • 文献情報:
    Speisky D et al. Molecular profiling of pancreatic neuroendocrine tumors in sporadic and Von Hippel-Lindau patients. Clin. Cancer Res. 2012 May;18(10):2838-49
    Speisky D et al
    2012/01/01
  • 備考:
    Applications: IHC, Species: Human
  • 参照:
    PubMed
  • No.: 32
  • 文献情報:
    Onishi H et al. Hedgehog inhibitor decreases chemosensitivity to 5-fluorouracil and gemcitabine under hypoxic conditions in pancreatic cancer. Cancer Sci 2012 Apr;
    Onishi H et al
    2012/01/01
  • 備考:
    Applications: IHC, IF, Species: Mouse
  • 参照:
    PubMed
  • No.: 33
  • 文献情報:
    Pellegrini L et al. SIRT3 protects from hypoxia and staurosporine-mediated cell death by maintaining mitochondrial membrane potential and intracellular pH. Cell Death Differ 2012 May;
    Pellegrini L et al
    2012/01/01
  • 備考:
    Applications: WB, Species: Human
  • 参照:
    PubMed
  • No.: 34
  • 文献情報:
    Muriel L坦pez C et al. Predictive factors for response to treatment in patients with advanced renal cell carcinoma. Invest New Drugs 2012 May;
    Muriel L坦pez C et al
    2012/01/01
  • 備考:
    Applications: IHC, Species: Human
  • 参照:
    PubMed
  • No.: 35
  • 文献情報:
    Weber DC et al. The prognostic value of expression of HIF1α, EGFR and VEGF-A, in localized prostate cancer for intermediate- and high-risk patients treated with radiation therapy with or without androgen deprivation therapy. Radiat Oncol 2012;7:66
    Weber DC et al
    2012/01/01
  • 備考:
    Species: Human, Applications: IHC
  • 参照:
    PubMed
  • No.: 36
  • 文献情報:
    Eguchi D et al. Hypoxia enhances the interaction between pancreatic stellate cells and cancer cells via increased secretion of connective tissue growth factor. J Surg Res 2012 Jul;
    Eguchi D et al
    2012/01/01
  • 備考:
    Species: Human, Applications: IHC
  • 参照:
    PubMed
  • No.: 37
  • 文献情報:
    Brouillet S et al. EG-VEGF controls placental growth and survival in normal and pathological pregnancies: case of fetal growth restriction (FGR). Cell. Mol. Life Sci. 2012 Sep;
    Brouillet S et al
    2012/01/01
  • 備考:
    Species: Human, Applications: IHC
  • 参照:
    PubMed
  • No.: 38
  • 文献情報:
    Fromy B et al. Asic3 is a neuronal mechanosensor for pressure-induced vasodilation that protects against pressure ulcers. Nat Med 2012 Jul;
    Fromy B et al
    2012/01/01
  • 備考:
    Species: Mouse, Applications: IHC
  • 参照:
    PubMed
  • No.: 39
  • 文献情報:
    Engler JR et al. Increased microglia/macrophage gene expression in a subset of adult and pediatric astrocytomas. PLoS ONE 2012;7(8):e43339
    Engler JR et al
    2012/01/01
  • 備考:
    Species: Human, Applications: IHC
  • 参照:
    PubMed
  • No.: 40
  • 文献情報:
    Piao Y et al. Glioblastoma resistance to anti-VEGF therapy is associated with myeloid cell infiltration, stem cell accumulation, and a mesenchymal phenotype. Neuro-oncology 2012 Nov;14(11):1379-92
    Piao Y et al
    2012/01/01
  • 備考:
    Applications: IHC
  • 参照:
    PubMed
  • No.: 41
  • 文献情報:
    Muriel L坦pez C et al. Prognostic factors in patients with advanced renal cell carcinoma. Clin Genitourin Cancer 2012 Dec;10(4):262-70
    Muriel L坦pez C et al
    2012/01/01
  • 備考:
    Applications: IHC
  • 参照:
    PubMed
  • No.: 42
  • 文献情報:
    Currie MJ et al. Immunohistochemical analysis of cancer stem cell markers in invasive breast carcinoma and associated ductal carcinoma in situ: relationships with markers of tumor hypoxia and microvascularity. Hum. Pathol. 2012 Oct;
    Currie MJ et al
    2012/01/01
  • 備考:
    Species: Human, Applications: IHC
  • 参照:
    PubMed
  • No.: 43
  • 文献情報:
    Proescholdt MA et al. Function of carbonic anhydrase IX in glioblastoma multiforme. Neuro-oncology 2012 Nov;14(11):1357-66
    Proescholdt MA et al
    2012/01/01
  • 備考:
    Species: Human, Applications: IHC, WB
  • 参照:
    PubMed
  • No.: 44
  • 文献情報:
    Pinato DJ et al. Immunohistochemical markers of the hypoxic response can identify malignancy in phaeochromocytomas and paragangliomas and optimize the detection of tumours with VHL germline mutations. Br. J. Cancer 2013 Feb;108(2):429-37
    Pinato DJ et al
    2013/01/01
  • 備考:
    Species: Human, Applications: IHC
  • 参照:
    PubMed
  • No.: 45
  • 文献情報:
    Zhang Q et al. Wnt/β-catenin signaling enhances hypoxia-induced epithelial-mesenchymal transition in hepatocellular carcinoma via crosstalk with hif-1α signaling. Carcinogenesis 2013 Mar;
    Zhang Q et al
    2013/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 46
  • 文献情報:
    Yin S et al. Arylsulfonamide KCN1 inhibits in vivo glioma growth and interferes with HIF signaling by disrupting HIF-1α interaction with cofactors p300/CBP. Clin. Cancer Res. 2012 Dec;18(24):6623-33
    Yin S et al
    2012/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 47
  • 文献情報:
    Kato Y et al. Expression of a hypoxia-associated protein, carbonic anhydrase-9, correlates with malignant phenotypes of gastric carcinoma. Digestion 2010;82(4):246-51
    Kato Y et al
    2010/01/01
  • 備考:
    Species: Human, Applications: IHC
  • 参照:
    PubMed
  • No.: 48
  • 文献情報:
    Aarntzen EH et al. Targeting of 111In-Labeled Dendritic Cell Human Vaccines Improved by Reducing Number of Cells. Clin. Cancer Res. 2013 Mar;19(6):1525-1533
    Aarntzen EH et al
    2013/01/01
  • 備考:
    Species: Human, Applications: IHC
  • 参照:
    PubMed
  • No.: 49
  • 文献情報:
    Delhaas T et al. Steep increase in myonuclear domain size during infancy. Anat Rec (Hoboken) 2013 Feb;296(2):192-7
    Delhaas T et al
    2013/01/01
  • 備考:
    Species: Human, Applications: IHC, ICC/IF
  • 参照:
    PubMed
  • No.: 50
  • 文献情報:
    Arvidsson Y et al. Hypoxia stimulates CXCR4 signalling in ileal carcinoids. Endocr. Relat. Cancer 2010 Jun;17(2):303-16
    Arvidsson Y et al
    2010/01/01
  • 備考:
    Species: Human, Applications: IHC
  • 参照:
    PubMed
  • No.: 51
  • 文献情報:
    Cho SY et al. Activation of AMP-Activated Protein Kinase α and Extracelluar Signal-Regulated Kinase Mediates CB-PIC-Induced Apoptosis in Hypoxic SW620 Colorectal Cancer Cells. Evid Based Complement Alternat Med 2013;2013:974313
    Cho SY et al
    2013/01/01
  • 備考:
    Species: Human, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 52
  • 文献情報:
    Li Y et al. Antibody-specific detection of CAIX in breast and prostate cancers. Biochem. Biophys. Res. Commun. 2009 Aug;386(3):488-92
    Li Y et al
    2009/01/01
  • 備考:
    Species: Human, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 53
  • 文献情報:
    Carbonell WS et al. β1 integrin targeting potentiates antiangiogenic therapy and inhibits the growth of bevacizumab-resistant glioblastoma. Cancer Res. 2013 May;73(10):3145-54
    Carbonell WS et al
    2013/01/01
  • 備考:
    Species: Human, Applications: IHC-P, ICC/IF
  • 参照:
    PubMed
  • No.: 54
  • 文献情報:
    Gauter-Fleckenstein B et al. Comparison of two Mn porphyrin-based mimics of superoxide dismutase in pulmonary radioprotection. Free Radic. Biol. Med. 2008 Mar;44(6):982-9
    Gauter-Fleckenstein B et al
    2008/01/01
  • 備考:
    Species: Rat, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 55
  • 文献情報:
    Bussolati B et al. Renal CD133+/CD73+ Progenitors Produce Erythropoietin under Hypoxia and Prolyl Hydroxylase Inhibition. J. Am. Soc. Nephrol. 2013 Jul;24(8):1234-41
    Bussolati B et al
    2013/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 56
  • 文献情報:
    Baia GS et al. An orthotopic skull base model of malignant meningioma. Brain Pathol. 2008 Apr;18(2):172-9
    Baia GS et al
    2008/01/01
  • 備考:
    Species: Mouse, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 57
  • 文献情報:
    Park I et al. Evaluation of heterogeneous metabolic profile in an orthotopic human glioblastoma xenograft model using compressed sensing hyperpolarized 3D 13C magnetic resonance spectroscopic imaging. Magn Reson Med 2013 Jul;70(1):33-9
    Park I et al
    2013/01/01
  • 備考:
    Species: Rat, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 58
  • 文献情報:
    Dubois L et al. Targeting carbonic anhydrase IX by nitroimidazole based sulfamides enhances the therapeutic effect of tumor irradiation: A new concept of dual targeting drugs. Radiother Oncol 2013 Jul;
    Dubois L et al
    2013/01/01
  • 備考:
    Species: Mouse, Applications: IHC-Fr
  • 参照:
    PubMed
  • No.: 59
  • 文献情報:
    Kumar S et al. Tumor dynamics in response to antiangiogenic therapy with oral metronomic topotecan and pazopanib in neuroblastoma xenografts. Transl Oncol 2013 Aug;6(4):493-503
    Kumar S et al
    2013/01/01
  • 備考:
    Species: Human, Applications: IHC
  • 参照:
    PubMed
  • No.: 60
  • 文献情報:
    Pistollato F et al. Interaction of hypoxia-inducible factor-1α and Notch signaling regulates medulloblastoma precursor proliferation and fate. Stem Cells 2010 Nov;28(11):1918-29
    Pistollato F et al
    2010/01/01
  • 備考:
    Species: Human, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 61
  • 文献情報:
    Pistollato F et al. Intratumoral hypoxic gradient drives stem cells distribution and MGMT expression in glioblastoma. Stem Cells 2010 May;28(5):851-62
    Pistollato F et al
    2010/01/01
  • 備考:
    Species: Human, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 62
  • 文献情報:
    Campanile C et al. Characterization of Different Osteosarcoma Phenotypes by PET Imaging in Preclinical Animal Models. J. Nucl. Med. 2013 Aug;54(8):1362-8
    Campanile C et al
    2013/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 63
  • 文献情報:
    Albert S et al. Prognostic value of the chemokine receptor CXCR4 and epithelial-to-mesenchymal transition in patients with squamous cell carcinoma of the mobile tongue. Oral Oncol. 2012 Jul;
    Albert S et al
    2012/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 64
  • 文献情報:
    Wen YA et al. Downregulation of PHLPP expression contributes to hypoxia-induced resistance to chemotherapy in colon cancer cells. Mol. Cell. Biol. 2013 Nov;33(22):4594-605
    Wen YA et al
    2013/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 65
  • 文献情報:
    El-Heliebi A et al. Are morphological criteria sufficient for the identification of circulating tumor cells in renal cancer? J Transl Med 2013;11:214
    El-Heliebi A et al
    2013/01/01
  • 備考:
    Species: Human, Applications: ICC/IF
  • 参照:
    PubMed
  • No.: 66
  • 文献情報:
    F辰hling M et al. Tubular von Hippel-Lindau knockout protects against rhabdomyolysis-induced AKI. J. Am. Soc. Nephrol. 2013 Nov;24(11):1806-19
    F辰hling M et al
    2013/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 67
  • 文献情報:
    Cioffi S et al. Tbx1 regulates brain vascularization. Hum. Mol. Genet. 2014 Jan;23(1):78-89
    Cioffi S et al
    2014/01/01
  • 備考:
    Species: Mouse, Applications: IHC-Fr, ICC/IF
  • 参照:
    PubMed
  • No.: 68
  • 文献情報:
    Zhang M et al. The use of porous scaffold as a tumor model. Int J Biomater 2013;2013:396056
    Zhang M et al
    2013/01/01
  • 備考:
    Species: Human, Applications: IHC
  • 参照:
    PubMed
  • No.: 69
  • 文献情報:
    Pinato DJ et al. An expression signature of the angiogenic response in gastrointestinal neuroendocrine tumours: correlation with tumour phenotype and survival outcomes. Br. J. Cancer 2014 Jan;110(1):115-22
    Pinato DJ et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 70
  • 文献情報:
    Motzer RJ et al. Investigation of novel circulating proteins, germ line single-nucleotide polymorphisms, and molecular tumor markers as potential efficacy biomarkers of first-line sunitinib therapy for advanced renal cell carcinoma. Cancer Chemother. Phar
    Motzer RJ et al
    2014/01/01
  • 備考:
    Species: Human, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 71
  • 文献情報:
    Santos CD et al. Effects of preset sequential administrations of sunitinib and everolimus on tumour differentiation in Caki-1 renal cell carcinoma. Br. J. Cancer 2015 Jan;112(1):86-94
    Santos CD et al
    2015/01/01
  • 備考:
    Species: Human, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 72
  • 文献情報:
    Sadlecki P et al. The role of Hypoxia-inducible factor-1 α , glucose transporter-1, (GLUT-1) and carbon anhydrase IX in endometrial cancer patients. Biomed Res Int 2014;2014:616850
    Sadlecki P et al
    2014/01/01
  • 備考:
    Species: Human, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 73
  • 文献情報:
    Kwon OJ et al. HIF-1α and CA-IX as predictors of locoregional control for determining the optimal treatment modality for early-stage laryngeal carcinoma. Head Neck 2014 Feb;
    Kwon OJ et al
    2014/01/01
  • 備考:
    Species: Human, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 74
  • 文献情報:
    Chen LQ et al. Assessment of carbonic anhydrase IX expression and extracellular pH in B-cell lymphoma cell line models. Leuk. Lymphoma 2014 Nov;:1-8
    Chen LQ et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 75
  • 文献情報:
    Hwa JS et al. The prognostic value of immunohistochemical markers for oral tongue squamous cell carcinoma. Eur Arch Otorhinolaryngol 2014 Aug;
    Hwa JS et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 76
  • 文献情報:
    Chen X et al. XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway. Nature 2014 Apr;508(7494):103-7
    Chen X et al
    2014/01/01
  • 備考:
    Species: Human, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 77
  • 文献情報:
    Kang HJ et al. Expression of carbonic anhydrase 9 is a novel prognostic marker in resectable hepatocellular carcinoma. Virchows Arch. 2015 Jan;
    Kang HJ et al
    2015/01/01
  • 備考:
    Species: Human, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 78
  • 文献情報:
    Lin XY et al. Expression and diagnostic implications of carbonic anhydrase IX in several tumours with predominantly clear cell morphology. Histopathology 2015 Apr;66(5):685-94
    Lin XY et al
    2015/01/01
  • 備考:
    Species: Human, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 79
  • 文献情報:
    Gellert LL et al. The diagnostic accuracy of percutaneous renal needle core biopsy and its potential impact on the clinical management of renal cortical neoplasms. Arch. Pathol. Lab. Med. 2014 Dec;138(12):1673-9
    Gellert LL et al
    2014/01/01
  • 備考:
    Species: Human, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 80
  • 文献情報:
    Lee HJ et al. Inhibition of vascular endothelial growth factor a and hypoxia-inducible factor 1α maximizes the effects of radiation in sarcoma mouse models through destruction of tumor vasculature. Int. J. Radiat. Oncol. Biol. Phys. 2015 Mar;91(3):6
    Lee HJ et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 81
  • 文献情報:
    Janmohamed SR et al. Support for the hypoxia theory in the pathogenesis of infantile haemangioma. Clin. Exp. Dermatol. 2014 Dec;
    Janmohamed SR et al
    2014/01/01
  • 備考:
    Species: Human, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 82
  • 文献情報:
    Morifuji Y et al. Reoxygenation from chronic hypoxia promotes metastatic processes in pancreatic cancer through the Hedgehog signaling. Cancer Sci. 2014 Mar;105(3):324-33
    Morifuji Y et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 83
  • 文献情報:
    Polaナгki R et al. Activity of the monocarboxylate transporter 1 inhibitor AZD3965 in small cell lung cancer. Clin. Cancer Res. 2014 Feb;20(4):926-37
    Polaナгki R et al
    2014/01/01
  • 備考:
    Applications: IHC
  • 参照:
    PubMed
  • No.: 84
  • 文献情報:
    Cotroneo E et al. Iron homeostasis and pulmonary hypertension: iron deficiency leads to pulmonary vascular remodeling in the rat. Circ. Res. 2015 May;116(10):1680-90
    Cotroneo E et al
    2015/01/01
  • 備考:
    Species: Rat, Applications: IHC
  • 参照:
    PubMed
  • No.: 85
  • 文献情報:
    Dulloo I et al. Hypoxia-inducible TAp73 supports tumorigenesis by regulating the angiogenic transcriptome. Nat. Cell Biol. 2015 Apr;17(4):511-23
    Dulloo I et al
    2015/01/01
  • 備考:
    Species: Human, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 86
  • 文献情報:
    Heijmen L et al. Monitoring the effects of bevacizumab beyond progression in a murine colorectal cancer model: a functional imaging approach. Invest New Drugs 2013 Jan;
    Heijmen L et al
    2013/01/01
  • 備考:
    Species: Mouse, Applications: IHC, ICC/IF
  • 参照:
    PubMed
  • No.: 87
  • 文献情報:
    Heijmen L et al. Monitoring hypoxia and vasculature during bevacizumab treatment in a murine colorectal cancer model. Contrast Media Mol Imaging ;9(3):237-45
    Heijmen L et al
  • 備考:
    Species: Human, Applications: IHC-Fr
  • 参照:
    PubMed
  • No.: 88
  • 文献情報:
    Zhou GX et al. Quantification of carbonic anhydrase IX expression in serum and tissue of renal cell carcinoma patients using enzyme-linked immunosorbent assay: prognostic and diagnostic potentials. Urology 2010 Feb;75(2):257-61
    Zhou GX et al
    2010/01/01
  • 備考:
    Species: Human, Applications: ELISA
  • 参照:
    PubMed
  • No.: 89
  • 文献情報:
    Kinoshita H et al. Diffuse-type gastric cancer cells switch their driver pathways from FGFR2 signaling to SDF1/CXCR4 axis in hypoxic tumor microenvironments. Carcinogenesis 2015 Dec;36(12):1511-20
    Kinoshita H et al
    2015/01/01
  • 備考:
    Species: Mouse, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 90
  • 文献情報:
    Ward C et al. Evaluation of carbonic anhydrase IX as a therapeutic target for inhibition of breast cancer invasion and metastasis using a series of in vitro breast cancer models. Oncotarget 2015 Sep;6(28):24856-70
    Ward C et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 91
  • 文献情報:
    Hong YS et al. Carbonic anhydrase 9 is a predictive marker of survival benefit from lower dose of bevacizumab in patients with previously treated metastatic colorectal cancer. BMC Cancer 2009;9:246
    Hong YS et al
    2009/01/01
  • 備考:
    Species: Human, Applications: IHC
  • 参照:
    PubMed
  • No.: 92
  • 文献情報:
    Skapa P et al. Carbonic anhydrase IX expression in clear cell renal cell carcinomas negatively correlates with the proportion of the granular cell component. J. Clin. Oncol. 2008 Aug;26(22):3809-11; author reply 3811-2
    Skapa P et al
    2008/01/01
  • 備考:
    Species: Human
  • 参照:
    PubMed
  • No.: 93
  • 文献情報:
    Al-Ahmadie HA et al. Carbonic anhydrase IX expression in clear cell renal cell carcinoma: an immunohistochemical study comparing 2 antibodies. Am. J. Surg. Pathol. 2008 Mar;32(3):377-82
    Al-Ahmadie HA et al
    2008/01/01
  • 備考:
    Species: Human, Applications: IHC
  • 参照:
    PubMed
  • No.: 94
  • 文献情報:
    Bachmann IM et al. Tumor necrosis is associated with increased alphavbeta3 integrin expression and poor prognosis in nodular cutaneous melanomas. BMC Cancer 2008;8:362
    Bachmann IM et al
    2008/01/01
  • 備考:
    Species: Human, Applications: IHC
  • 参照:
    PubMed
  • No.: 95
  • 文献情報:
    O"Toole D et al. Molecular markers associated with response to chemotherapy in gastro-entero-pancreatic neuroendocrine tumors. Endocr. Relat. Cancer 2010 Dec;17(4):847-56
    O"Toole D et al
    2010/01/01
  • 備考:
    Species: Human, Applications: IHC
  • 参照:
    PubMed
  • No.: 96
  • 文献情報:
    Yoon C et al. Hypoxia-activated chemotherapeutic TH-302 enhances the effects of VEGF-A inhibition and radiation on sarcomas. Br. J. Cancer 2015 Jun;113(1):46-56
    Yoon C et al
    2015/01/01
  • 備考:
    Species: Human, Applications: IHC-P, ICC/IF
  • 参照:
    PubMed
  • No.: 97
  • 文献情報:
    Jamali S et al. Hypoxia-induced carbonic anhydrase IX facilitates lactate flux in human breast cancer cells by non-catalytic function. Sci Rep 2015;5:13605
    Jamali S et al
    2015/01/01
  • 備考:
    Species: Human, Applications: WB, ICC/IF
  • 参照:
    PubMed
  • No.: 98
  • 文献情報:
    Nelson MP et al. IL-33 and M2a alveolar macrophages promote lung defense against the atypical fungal pathogen Pneumocystis murina. J. Immunol. 2011 Feb;186(4):2372-81
    Nelson MP et al
    2011/01/01
  • 備考:
    Applications: ChIP
  • 参照:
    PubMed
  • No.: 99
  • 文献情報:
    Nakao M et al. Prognostic significance of carbonic anhydrase IX expression by cancer-associated fibroblasts in lung adenocarcinoma. Cancer 2009 Jun;115(12):2732-43
    Nakao M et al
    2009/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 100
  • 文献情報:
    Eikrem O et al. Transcriptome Sequencing (RNAseq) Enables Utilization of Formalin-Fixed, Paraffin-Embedded Biopsies with Clear Cell Renal Cell Carcinoma for Exploration of Disease Biology and Biomarker Development. PLoS ONE 2016;11(2):e0149743
    Eikrem O et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 101
  • 文献情報:
    Islam SS et al. Simultaneous Targeting of Bladder Tumor Growth, Survival, and Epithelial-to-Mesenchymal Transition with a Novel Therapeutic Combination of Acetazolamide (AZ) and Sulforaphane (SFN). Target Oncol 2016 Apr;11(2):209-27
    Islam SS et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 102
  • 文献情報:
    Song CW et al. Indirect Tumor Cell Death After High-Dose Hypofractionated Irradiation: Implications for Stereotactic Body Radiation Therapy and Stereotactic Radiation Surgery. Int. J. Radiat. Oncol. Biol. Phys. 2015 Sep;93(1):166-72
    Song CW et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 103
  • 文献情報:
    Andr辿 H et al. Hypoxia-Inducible Factor-1α Is Associated With Sprouting Angiogenesis in the Murine Laser-Induced Choroidal Neovascularization Model. Invest. Ophthalmol. Vis. Sci. 2015 Oct;56(11):6591-604
    Andr辿 H et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 104
  • 文献情報:
    Badar T et al. Phase I study of evofosfamide, an investigational hypoxia-activated prodrug, in patients with advanced leukemia. Am. J. Hematol. 2016 Aug;91(8):800-5
    Badar T et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 105
  • 文献情報:
    Scholz A et al. Endothelial cell-derived angiopoietin-2 is a therapeutic target in treatment-naive and bevacizumab-resistant glioblastoma. EMBO Mol Med 2016 Jan;8(1):39-57
    Scholz A et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 106
  • 文献情報:
    Leek R et al. Methods: Using Three-Dimensional Culture (Spheroids) as an In Vitro Model of Tumour Hypoxia. Adv. Exp. Med. Biol. 2016;899:167-96
    Leek R et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 107
  • 文献情報:
    Ono M et al. Enhanced snoMEN Vectors Facilitate Establishment of GFP-HIF-1α Protein Replacement Human Cell Lines. PLoS ONE 2016;11(4):e0154759
    Ono M et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 108
  • 文献情報:
    Baine MK et al. Characterization of tumor infiltrating lymphocytes in paired primary and metastatic renal cell carcinoma specimens. Oncotarget 2015 Sep;6(28):24990-5002
    Baine MK et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 109
  • 文献情報:
    Newton IP et al. Adenomatous polyposis coli and hypoxia-inducible factor-1{alpha} have an antagonistic connection. Mol. Biol. Cell 2010 Nov;21(21):3630-8
    Newton IP et al
    2010/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 110
  • 文献情報:
    Mitsuhashi A et al. Fibrocyte-like cells mediate acquired resistance to anti-angiogenic therapy with bevacizumab. Nat Commun 2015;6:8792
    Mitsuhashi A et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 111
  • 文献情報:
    He H et al. A Sensitive IHC Method for Monitoring Autophagy-Specific Markers in Human Tumor Xenografts. J Biomark 2016;2016:1274603
    He H et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 112
  • 文献情報:
    Xu W et al. Increased mitochondrial arginine metabolism supports bioenergetics in asthma. J. Clin. Invest. 2016 Jul;126(7):2465-81
    Xu W et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 113
  • 文献情報:
    Chaudary N et al. Characterization of the Tumor-Microenvironment in Patient-Derived Cervix Xenografts (OCICx). Cancers (Basel) 2012;4(3):821-45
    Chaudary N et al
    2012/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 114
  • 文献情報:
    Park I et al. Hyperpolarized 13C magnetic resonance metabolic imaging: application to brain tumors. Neuro-oncology 2010 Feb;12(2):133-44
    Park I et al
    2010/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 115
  • 文献情報:
    Hecht JL et al. Revisiting decidual vasculopathy. Placenta 2016 Jun;42:37-43
    Hecht JL et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 116
  • 文献情報:
    Di Napoli A et al. Tissue biomarkers in renal cell carcinoma: issues and solutions. Cancer 2009 May;115(10 Suppl):2290-7
    Di Napoli A et al
    2009/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 117
  • 文献情報:
    Dumais J. Plant morphogenesis: a role for mechanical signals. Curr. Biol. 2009 Mar;19(5):R207-8
    Dumais J
    2009/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 118
  • 文献情報:
    Ferecatu I et al. Dysfunction in the mitochondrial Fe-S assembly machinery leads to formation of the chemoresistant truncated VDAC1 isoform without HIF-1α activation. PLoS ONE 2018;13(3):e0194782
    Ferecatu I et al
    2018/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 119
  • 文献情報:
    Steenbrugge J et al. Anti-inflammatory signaling by mammary tumor cells mediates prometastatic macrophage polarization in an innovative intraductal mouse model for triple-negative breast cancer. J. Exp. Clin. Cancer Res. 2018 Aug;37(1):191
    Steenbrugge J et al
    2018/01/01
  • 備考:
    Species: Mouse, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 120
  • 文献情報:
    Young JR et al. Utility of multiphasic multidetector computed tomography in discriminating between clear cell renal cell carcinomas with high and low carbonic anhydrase-IX expression. Abdom Radiol (NY) 2018 Oct;43(10):2734-2742
    Young JR et al
    2018/01/01
  • 備考:
    Applications: IHC
  • 参照:
    PubMed
  • No.: 121
  • 文献情報:
    Radoul M et al. MR Studies of Glioblastoma Models Treated with Dual PI3K/mTOR Inhibitor and Temozolomide:Metabolic Changes Are Associated with Enhanced Survival. Mol. Cancer Ther. 2016 05;15(5):1113-22
    Radoul M et al
    2016/01/01
  • 備考:
    Species: Mouse, Applications: IHC
  • 参照:
    PubMed
  • No.: 122
  • 文献情報:
    Yoon C et al. Multimodal targeting of tumor vasculature and cancer stem-like cells in sarcomas with VEGF-A inhibition, HIF-1α inhibition, and hypoxia-activated chemotherapy. Oncotarget 2016 Jul;7(28):42844-42858
    Yoon C et al
    2016/01/01
  • 備考:
    Species: Mouse
  • 参照:
    PubMed
  • No.: 123
  • 文献情報:
    Guo J et al. Hypoxia suppresses cylindromatosis (CYLD) expression to promote inflammation in glioblastoma: possible link to acquired resistance to anti-VEGF therapy. Oncotarget 2014 Aug;5(15):6353-64
    Guo J et al
    2014/01/01
  • 備考:
    Species: Human, Applications: IHC
  • 参照:
    PubMed
  • No.: 124
  • 文献情報:
    Balasundaram G et al. Noninvasive Anatomical and Functional Imaging of Orthotopic Glioblastoma Development and Therapy using Multispectral Optoacoustic Tomography. Transl Oncol 2018 Oct;11(5):1251-1258
    Balasundaram G et al
    2018/01/01
  • 備考:
    Species: Mouse, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 125
  • 文献情報:
    Rosenberg T et al. Heterogenic expression of stem cell markers in patient-derived glioblastoma spheroid cultures exposed to long-term hypoxia. CNS Oncol 2018 Apr;7(2):CNS15
    Rosenberg T et al
    2018/01/01
  • 備考:
    Species: Human, Applications: IHC
  • 参照:
    PubMed
  • No.: 126
  • 文献情報:
    Eikrem OS et al. Development and confirmation of potential gene classifiers of human clear cell renal cell carcinoma using next-generation RNA sequencing. Scand J Urol 2016 Dec;50(6):452-462
    Eikrem OS et al
    2016/01/01
  • 備考:
    Species: Human, Applications: IHC
  • 参照:
    PubMed
  • No.: 127
  • 文献情報:
    Kim EN et al. A Pyloric Gland-Phenotype Ovarian Mucinous Tumor Resembling Lobular Endocervical Glandular Hyperplasia in a Patient with Peutz-Jeghers Syndrome. J Pathol Transl Med 2017 Mar;51(2):159-164
    Kim EN et al
    2017/01/01
  • 備考:
    Applications: IHC-P
  • 参照:
    PubMed
  • No.: 128
  • 文献情報:
    Davis RM et al. Surface-Enhanced Raman Scattering Nanoparticles for Multiplexed Imaging of Bladder Cancer Tissue Permeability and Molecular Phenotype. ACS Nano 2018 Oct;12(10):9669-9679
    Davis RM et al
    2018/01/01
  • 備考:
    Species: Human, Applications: ICC/IF
  • 参照:
    PubMed
  • No.: 129
  • 文献情報:
    Corbet C et al. Interruption of lactate uptake by inhibiting mitochondrial pyruvate transport unravels direct antitumor and radiosensitizing effects. Nat Commun 2018 03;9(1):1208
    Corbet C et al
    2018/01/01
  • 備考:
    Species: Human, Applications: IHC
  • 参照:
    PubMed
  • No.: 130
  • 文献情報:
    Bulusu V et al. Acetate Recapturing by Nuclear Acetyl-CoA Synthetase 2 Prevents Loss of Histone Acetylation during Oxygen and Serum Limitation. Cell Rep 2017 01;18(3):647-658
    Bulusu V et al
    2017/01/01
  • 備考:
    Species: Human, Applications: IHC
  • 参照:
    PubMed
  • No.: 131
  • 文献情報:
    Wang D et al. BIRC3 is a biomarker of mesenchymal habitat of glioblastoma, and a mediator of survival adaptation in hypoxia-driven glioblastoma habitats. Sci Rep 2017 Aug;7(1):9350
    Wang D et al
    2017/01/01
  • 備考:
    Species: Mouse, Applications: WB
  • 参照:
    PubMed
  • No.: 132
  • 文献情報:
    Dreyer-Andersen N et al. Intermittent, low dose carbon monoxide exposure enhances survival and dopaminergic differentiation of human neural stem cells. PLoS ONE 2018;13(1):e0191207
    Dreyer-Andersen N et al
    2018/01/01
  • 備考:
    Species: Human, Applications: ICC/IF
  • 参照:
    PubMed
  • No.: 133
  • 文献情報:
    Tsuji T et al. Dissecting the Process of Activation of Cancer-promoting Zinc-requiring Ectoenzymes by Zinc Metalation Mediated by ZNT Transporters. J. Biol. Chem. 2017 02;292(6):2159-2173
    Tsuji T et al
    2017/01/01
  • 備考:
    WB
  • 参照:
    PubMed
  • No.: 134
  • 文献情報:
    Li Y et al. Expression and activity of carbonic anhydrase IX is associated with metabolic dysfunction in MDA-MB-231 breast cancer cells. Cancer Invest. 2009 Jul;27(6):613-23
    Li Y et al
    2009/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 135
  • 文献情報:
    Meijer TW et al. Tumor microenvironmental changes induced by the sulfamate carbonic anhydrase IX inhibitor S4 in a laryngeal tumor model. PLoS ONE 2014;9(9):e108068
    Meijer TW et al
    2014/01/01
  • 備考:
    Species: Mouse, Applications: IHC
  • 参照:
    PubMed
  • No.: 136
  • 文献情報:
    Ames S et al. The proteoglycan-like domain of carbonic anhydrase IX mediates non-catalytic facilitation of lactate transport in cancer cells. Oncotarget 2018 Jun;9(46):27940-27957
    Ames S et al
    2018/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 137
  • 文献情報:
    Bucau M et al. 18F-FDG Uptake in Well-Differentiated Neuroendocrine Tumors Correlates with Both Ki-67 and VHL Pathway Inactivation. Neuroendocrinology 2018;106(3):274-282
    Bucau M et al
    2018/01/01
  • 備考:
    Species: Human, Applications:
  • 参照:
    PubMed
  • No.: 138
  • 文献情報:
    Hirakawa T et al. Pancreatic Fibroblasts Stimulate the Motility of Pancreatic Cancer Cells through IGF1/IGF1R Signaling under Hypoxia. PLoS ONE 2016;11(8):e0159912
    Hirakawa T et al
    2016/01/01
  • 備考:
    Species: Human, Applications: IHC
  • 参照:
    PubMed
  • No.: 139
  • 文献情報:
    Zhang Y et al. Maintenance of antiangiogenic and antitumor effects by orally active low-dose capecitabine for long-term cancer therapy. Proc. Natl. Acad. Sci. U.S.A. 2017 06;114(26):E5226-E5235
    Zhang Y et al
    2017/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 140
  • 文献情報:
    Nakamura M et al. Off-tumor targets compromise antiangiogenic drug sensitivity by inducing kidney erythropoietin production. Proc. Natl. Acad. Sci. U.S.A. 2017 11;114(45):E9635-E9644
    Nakamura M et al
    2017/01/01
  • 備考:
    Species: Mouse, Applications:
  • 参照:
    PubMed
  • No.: 141
  • 文献情報:
    Bousquet G et al. Targeting autophagic cancer stem-cells to reverse chemoresistance in human triple negative breast cancer. Oncotarget 2017 May;8(21):35205-35221
    Bousquet G et al
    2017/01/01
  • 備考:
    Species: Human, Applications: ICC/IF
  • 参照:
    PubMed
  • No.: 142
  • 文献情報:
    Frost J et al. Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition. Nat Commun 2016 11;7:13312
    Frost J et al
    2016/01/01
  • 備考:
    WB
  • 参照:
    PubMed
  • No.: 143
  • 文献情報:
    Boyd NH et al. Addition of carbonic anhydrase 9 inhibitor SLC-0111 to temozolomide treatment delays glioblastoma growth in vivo. JCI Insight 2017 Dec;2(24)
    Boyd NH et al
    2017/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 144
  • 文献情報:
    Burman A et al. Localized hypoxia links ER stress to lung fibrosis through induction of C/EBP homologous protein. JCI Insight 2018 Aug;3(16)
    Burman A et al
    2018/01/01
  • 備考:
    Species: Mouse, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 145
  • 文献情報:
    Brossa A et al. Sunitinib but not VEGF blockade inhibits cancer stem cell endothelial differentiation. Oncotarget 2015 May;6(13):11295-309
    Brossa A et al
    2015/01/01
  • 備考:
    Species: Mouse, Applications: IHC, ICC/IF
  • 参照:
    PubMed
  • No.: 146
  • 文献情報:
    Fraga A et al. Genetic polymorphisms in key hypoxia-regulated downstream molecules and phenotypic correlation in prostate cancer. BMC Urol 2017 Jan;17(1):12
    Fraga A et al
    2017/01/01
  • 備考:
    Species: Human, Applications:
  • 参照:
    PubMed
  • No.: 147
  • 文献情報:
    Kasashima H et al. Lysyl oxidase is associated with the epithelial-mesenchymal transition of gastric cancer cells in hypoxia. Gastric Cancer 2016 Apr;19(2):431-42
    Kasashima H et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 148
  • 文献情報:
    Dachs GU et al. A profile of prognostic and molecular factors in European and Māori breast cancer patients. BMC Cancer 2010 Oct;10:543
    Dachs GU et al
    2010/01/01
  • 備考:
    Species: Human, Applications: IHC
  • 参照:
    PubMed
  • No.: 149
  • 文献情報:
    Tudisco L et al. Hypoxia activates placental growth factor expression in lymphatic endothelial cells. Oncotarget 2017 May;8(20):32873-32883
    Tudisco L et al
    2017/01/01
  • 備考:
    Species: Mouse, Applications: IHC
  • 参照:
    PubMed
  • No.: 150
  • 文献情報:
    Faes S et al. Targeting carbonic anhydrase IX improves the anti-cancer efficacy of mTOR inhibitors. Oncotarget 2016 Jun;7(24):36666-36680
    Faes S et al
    2016/01/01
  • 備考:
    Species: Mouse, Applications: IHC
  • 参照:
    PubMed
  • No.: 151
  • 文献情報:
    Huang Y et al. Antitumor and Antiangiogenic Effects of Aspirin-PC in Ovarian Cancer. Mol. Cancer Ther. 2016 Dec;15(12):2894-2904
    Huang Y et al
    2016/01/01
  • 備考:
    Species: Human, Applications: IHC
  • 参照:
    PubMed
  • No.: 152
  • 文献情報:
    van Kuijk SJ et al. The Sulfamate Small Molecule CAIX Inhibitor S4 Modulates Doxorubicin Efficacy. PLoS ONE 2016;11(8):e0161040
    van Kuijk SJ et al
    2016/01/01
  • 備考:
    Species: Human, Applications: IHC
  • 参照:
    PubMed
  • No.: 153
  • 文献情報:
    Stillebroer AB et al. Carbonic anhydrase IX in renal cell carcinoma: implications for prognosis, diagnosis, and therapy. Eur. Urol. 2010 Jul;58(1):75-83
    Stillebroer AB et al
    2010/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 154
  • 文献情報:
    Himmels P et al. Motor neurons control blood vessel patterning in the developing spinal cord. Nat Commun 2017 Mar;8:14583
    Himmels P et al
    2017/01/01
  • 備考:
    Species: Mouse, Applications: IHC-FR
  • 参照:
    PubMed
  • No.: 155
  • 文献情報:
    Klameth L et al. Small cell lung cancer: model of circulating tumor cell tumorospheres in chemoresistance. Sci Rep 2017 Jul;7(1):5337
    Klameth L et al
    2017/01/01
  • 備考:
    Species: Human, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 156
  • 文献情報:
    Cauchy F et al. Strong antineoplastic effects of metformin in preclinical models of liver carcinogenesis. Clin. Sci. 2017 01;131(1):27-36
    Cauchy F et al
    2017/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 157
  • 文献情報:
    Lambrechts D et al. Phenotype molding of stromal cells in the lung tumor microenvironment. Nat. Med. 2018 Aug;24(8):1277-1289
    Lambrechts D et al
    2018/01/01
  • 備考:
    Species: Human, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 158
  • 文献情報:
    Mudie S et al. PITX1, a specificity determinant in the HIF-1α-mediated transcriptional response to hypoxia. Cell Cycle 2014;13(24):3878-91
    Mudie S et al
    2014/01/01
  • 備考:
    WB
  • 参照:
    PubMed
  • No.: 159
  • 文献情報:
    Klier M et al. Catalytic activity of human carbonic anhydrase isoform IX is displayed both extra- and intracellularly. FEBS J. 2016 Jan;283(1):191-200
    Klier M et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 160
  • 文献情報:
    Greenhough A et al. Cancer cell adaptation to hypoxia involves a HIF-GPRC5A-YAP axis. EMBO Mol Med 2018 Nov;10(11)
    Greenhough A et al
    2018/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 161
  • 文献情報:
    Takenaka M et al. Iron regulatory protein 2 in ovarian endometrial cysts. Biochem. Biophys. Res. Commun. 2017 Jun;487(4):789-794
    Takenaka M et al
    2017/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 162
  • 文献情報:
    Iwamoto H et al. Cancer Lipid Metabolism Confers Antiangiogenic Drug Resistance. Cell Metab. 2018 Jul;28(1):104-117.e5
    Iwamoto H et al
    2018/01/01
  • 備考:
    ICC/IF
  • 参照:
    PubMed
  • No.: 163
  • 文献情報:
    Oh ET et al. NQO1 inhibits proteasome-mediated degradation of HIF-1α. Nat Commun 2016 Dec;7:13593
    Oh ET et al
    2016/01/01
  • 備考:
    Species: Mouse, Applications: IHC
  • 参照:
    PubMed
  • No.: 164
  • 文献情報:
    He L et al. Antiangiogenic effects of recombinant human endostatin in lung cancers. Mol Med Rep 2018 Jan;17(1):79-86
    He L et al
    2018/01/01
  • 備考:
    Species: Mouse, Applications:
  • 参照:
    PubMed
  • No.: 165
  • 文献情報:
    Toonen LJA et al. Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model. Mol Neurodegener 2018 06;13(1):31
    Toonen LJA et al
    2018/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 166
  • 文献情報:
    Kennedy JM et al. Clinical and morphologic review of 60 hereditary renal tumors from 30 hereditary renal cell carcinoma syndrome patients: lessons from a contemporary single institution series. Med Oncol 2019 Jul;36(9):74
    Kennedy JM et al
    2019/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 167
  • 文献情報:
    Pinato DJ et al. Programmed cell death ligands expression in phaeochromocytomas and paragangliomas: Relationship with the hypoxic response, immune evasion and malignant behavior. Oncoimmunology ;6(11):e1358332
    Pinato DJ et al
  • 備考:
  • 参照:
    PubMed
  • No.: 168
  • 文献情報:
    Steenbrugge J et al. Comparative Profiling of Metastatic 4T1- vs. Non-metastatic Py230-Based Mammary Tumors in an Intraductal Model for Triple-Negative Breast Cancer. Front Immunol 2019;10:2928
    Steenbrugge J et al
    2019/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 169
  • 文献情報:
    Ghosh P et al. Oxygen-Enhanced Optoacoustic Tomography Reveals the Effectiveness of Targeting Heme and Oxidative Phosphorylation at Normalizing Tumor Vascular Oxygenation. Cancer Res 2020 09;80(17):3542-3555
    Ghosh P et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 170
  • 文献情報:
    M辿hes G et al. Carbonic Anhydrase Inhibitor Acetazolamide Enhances CHOP Treatment Response and Stimulates Effector T-Cell Infiltration in A20/BalbC Murine B-Cell Lymphoma. Int J Mol Sci 2020 Jul;21(14)
    M辿hes G et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 171
  • 文献情報:
    Becker LM et al. Epigenetic Reprogramming of Cancer-Associated Fibroblasts Deregulates Glucose Metabolism and Facilitates Progression of Breast Cancer. Cell Rep 2020 06;31(9):107701
    Becker LM et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 172
  • 文献情報:
    Matolay O et al. Quantitative Analysis of Carbonic Anhydrase IX Uncovers Hypoxia-Related Functional Differences in Classical Hodgkin Lymphoma Subtypes. Int J Mol Sci 2019 Jul;20(14)
    Matolay O et al
    2019/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 173
  • 文献情報:
    Abdulfatah E et al. Clinicopathological characterisation of renal cell carcinoma in young adults: a contemporary update and review of literature. Histopathology 2020 May;76(6):875-887
    Abdulfatah E et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 174
  • 文献情報:
    Lovisa S et al. Endothelial-to-mesenchymal transition compromises vascular integrity to induce Myc-mediated metabolic reprogramming in kidney fibrosis. Sci Signal 2020 06;13(635)
    Lovisa S et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 175
  • 文献情報:
    Recondo G et al. Diverse Resistance Mechanisms to the Third-Generation ALK Inhibitor Lorlatinib in ALK-Rearranged Lung Cancer. Clin Cancer Res 2020 01;26(1):242-255
    Recondo G et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 176
  • 文献情報:
    Brown E et al. Mucosal inflammation downregulates PHD1 expression promoting a barrier-protective HIF-1α response in ulcerative colitis patients. FASEB J 2020 03;34(3):3732-3742
    Brown E et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 177
  • 文献情報:
    Fu SY et al. Sunitinib Treatment-elicited Distinct Tumor Microenvironment Dramatically Compensated the Reduction of Myeloid-derived Suppressor Cells. In Vivo ;34(3):1141-1152
    Fu SY et al
  • 備考:
  • 参照:
    PubMed
  • No.: 178
  • 文献情報:
    Kikuchi H et al. Chemotherapy-Induced IL8 Upregulates MDR1/ABCB1 in Tumor Blood Vessels and Results in Unfavorable Outcome. Cancer Res 2020 07;80(14):2996-3008
    Kikuchi H et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 179
  • 文献情報:
    Chen S et al. Eradication of tumor growth by delivering novel photothermal selenium-coated tellurium nanoheterojunctions. Sci Adv 2020 04;6(15):eaay6825
    Chen S et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 180
  • 文献情報:
    Hosaka K et al. Therapeutic paradigm of dual targeting VEGF and PDGF for effectively treating FGF-2 off-target tumors. Nat Commun 2020 07;11(1):3704
    Hosaka K et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 181
  • 文献情報:
    Ortmann B et al. CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells. J. Cell. Sci. 2016 Jan;129(1):191-205
    Ortmann B et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 182
  • 文献情報:
    Xiao Y et al. S100A10 Is a Critical Mediator of GAS6/AXL-Induced Angiogenesis in Renal Cell Carcinoma. Cancer Res 2019 11;79(22):5758-5768
    Xiao Y et al
    2019/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 183
  • 文献情報:
    Kuthi L et al. Clinicopathological Findings on 28 Cases with XP11.2 Renal Cell Carcinoma. Pathol Oncol Res 2020 Oct;26(4):2123-2133
    Kuthi L et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 184
  • 文献情報:
    Kim M et al. Comprehensive Immunoprofiles of Renal Cell Carcinoma Subtypes. Cancers (Basel) 2020 Mar;12(3)
    Kim M et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 185
  • 文献情報:
    Mikkelsen ML et al. Surgically induced ischemia has no impact on protein expression levels of HIF-1α and related biomarkers in renal cell carcinoma. APMIS 2021 Sep;129(9):535-547
    Mikkelsen ML et al
    2021/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 186
  • 文献情報:
    Anemone A et al. Tumour acidosis evaluated in vivo by MRI-CEST pH imaging reveals breast cancer metastatic potential. Br J Cancer 2021 01;124(1):207-216
    Anemone A et al
    2021/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 187
  • 文献情報:
    Alberti D et al. In vitro and in vivo BNCT investigations using a carborane containing sulfonamide targeting CAIX epitopes on malignant pleural mesothelioma and breast cancer cells. Sci Rep 2020 11;10(1):19274
    Alberti D et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 188
  • 文献情報:
    Dong Y et al. Tumor Xenografts of Human Clear Cell Renal Cell Carcinoma But Not Corresponding Cell Lines Recapitulate Clinical Response to Sunitinib: Feasibility of Using Biopsy Samples. Eur Urol Focus 2017 12;3(6):590-598
    Dong Y et al
    2017/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 189
  • 文献情報:
    Steenbrugge J et al. OMO-1 reduces progression and enhances cisplatin efficacy in a 4T1-based non-c-MET addicted intraductal mouse model for triple-negative breast cancer. NPJ Breast Cancer 2021 Mar;7(1):27
    Steenbrugge J et al
    2021/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 190
  • 文献情報:
    Mehibel M et al. Eliminating hypoxic tumor cells improves response to PARP inhibitors in homologous recombination-deficient cancer models. J Clin Invest 2021 Jun;131(11)
    Mehibel M et al
    2021/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 191
  • 文献情報:
    Gillen AE et al. Single-Cell RNA Sequencing of Childhood Ependymoma Reveals Neoplastic Cell Subpopulations That Impact Molecular Classification and Etiology. Cell Rep 2020 08;32(6):108023
    Gillen AE et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 192
  • 文献情報:
    Simko V et al. PIMT Binding to C-Terminal Ala459 of CAIX Is Involved in Inside-Out Signaling Necessary for Its Catalytic Activity. Int J Mol Sci 2020 Nov;21(22)
    Simko V et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 193
  • 文献情報:
    Menga A et al. Glufosinate constrains synchronous and metachronous metastasis by promoting anti-tumor macrophages. EMBO Mol Med 2020 10;12(10):e11210
    Menga A et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 194
  • 文献情報:
    Lin C et al. Fenofibrate inhibits hypoxia-inducible factor-1 alpha and carbonic anhydrase expression through activation of AMP-activated protein kinase/HO-1/Sirt1 pathway in glioblastoma cells. Environ Toxicol 2021 Dec;36(12):2551-2561
    Lin C et al
    2021/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 195
  • 文献情報:
    Pang L et al. Plasmacytoid dendritic cells recruited by HIF-1α/eADO/ADORA1 signaling induce immunosuppression in hepatocellular carcinoma. Cancer Lett 2021 Dec;522:80-92
    Pang L et al
    2021/01/01
  • 備考:
    Species: Human, Applications: IHC
  • 参照:
    PubMed
  • No.: 196
  • 文献情報:
    Wang Y et al. Histone citrullination by PADI4 is required for HIF-dependent transcriptional responses to hypoxia and tumor vascularization. Sci Adv 2021 Aug;7(35)
    Wang Y et al
    2021/01/01
  • 備考:
    Species: Human, Applications: IHC
  • 参照:
    PubMed