Anti-53BP1, Rabbit-Poly <Anti-p53 Binding Protein 1>

データシート

• 商品コード：NB100-304
• メーカー：NOV
• 包装：100μl
• 価格： ¥113,000
• 在庫：無(未発注)

マイリストに追加 マイリストに追加済

• No.： 1
• 文献情報：
  Riballo E et al. A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci. Mol. Cell 2004 Dec;16(5):715-24
  Riballo E et al
  2004/01/01
  
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• No.： 2
• 文献情報：
  Gomes J et al. Pteridium aquilinum and its ptaquiloside toxin induce DNA damage response in gastric epithelial cells, a link with gastric carcinogenesis. Toxicol. Sci. 2012 Mar;126(1):60-71
  Gomes J et al
  2012/01/01
  
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• No.： 3
• 文献情報：
  Singh M et al. Matrix metalloproteinases and their inhibitors and inducer in gestational trophoblastic diseases and normal placenta. Gynecol. Oncol. 2011 Jul;122(1):178-82
  Singh M et al
  2011/01/01
  
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• No.： 4
• 文献情報：
  Le ON et al. Ionizing radiation-induced long-term expression of senescence markers in mice is independent of p53 and immune status. Aging Cell 2010 Jun;9(3):398-409
  Le ON et al
  2010/01/01
  
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• No.： 5
• 文献情報：
  Dimitrova N et al. Cell cycle-dependent role of MRN at dysfunctional telomeres: ATM signaling-dependent induction of nonhomologous end joining (NHEJ) in G1 and resection-mediated inhibition of NHEJ in G2. Mol. Cell. Biol. 2009 Oct;29(20):5552-63
  Dimitrova N et al
  2009/01/01
  
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• 参照：
  

• No.： 6
• 文献情報：
  Mallette FA et al. RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites. EMBO J. 2012 Apr;31(8):1865-78
  Mallette FA et al
  2012/01/01
  
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• 参照：
  

• No.： 7
• 文献情報：
  Orsburn B et al. Differential requirement for H2AX and 53BP1 in organismal development and genome maintenance in the absence of poly(ADP)ribosyl polymerase 1. Mol. Cell. Biol. 2010 May;30(10):2341-52
  Orsburn B et al
  2010/01/01
  
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• 参照：
  

• No.： 8
• 文献情報：
  Hockemeyer D et al. Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres. Cell 2006 Jul;126(1):63-77
  Hockemeyer D et al
  2006/01/01
  
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• 参照：
  

• No.： 9
• 文献情報：
  Meng Y et al. Radiation-inducible immunotherapy for cancer: senescent tumor cells as a cancer vaccine. Mol. Ther. 2012 May;20(5):1046-55
  Meng Y et al
  2012/01/01
  
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• 参照：
  

• No.： 10
• 文献情報：
  Moon SH et al. Wild-type p53-induced phosphatase 1 dephosphorylates histone variant gamma-H2AX and suppresses DNA double strand break repair. J. Biol. Chem. 2010 Apr;285(17):12935-47
  Moon SH et al
  2010/01/01
  
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• 参照：
  

• No.： 11
• 文献情報：
  Fernandez-L A et al. Oncogenic YAP promotes radioresistance and genomic instability in medulloblastoma through IGF2-mediated Akt activation. Oncogene 2012 Apr;31(15):1923-37
  Fernandez-L A et al
  2012/01/01
  
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• 参照：
  

• No.： 12
• 文献情報：
  Fumagalli M et al. Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation. Nat. Cell Biol. 2012 Apr;14(4):355-65
  Fumagalli M et al
  2012/01/01
  
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• 参照：
  

• No.： 13
• 文献情報：
  Zhang M et al. Selective targeting of radiation-resistant tumor-initiating cells. Proc. Natl. Acad. Sci. U.S.A. 2010 Feb;107(8):3522-7
  Zhang M et al
  2010/01/01
  
• 備考：
  
• 参照：
  

• No.： 14
• 文献情報：
  Baldeyron C et al. HP1alpha recruitment to DNA damage by p150CAF-1 promotes homologous recombination repair. J. Cell Biol. 2011 Apr;193(1):81-95
  Baldeyron C et al
  2011/01/01
  
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• 参照：
  

• No.： 15
• 文献情報：
  Mortensen M et al. The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance. J. Exp. Med. 2011 Mar;208(3):455-67
  Mortensen M et al
  2011/01/01
  
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• 参照：
  

• No.： 16
• 文献情報：
  Hara MR et al. A stress response pathway regulates DNA damage through &#x3B2;2-adrenoreceptors and &#x3B2;-arrestin-1. Nature 2011 Sep;477(7364):349-53
  Hara MR et al
  2011/01/01
  
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• 参照：
  

• No.： 17
• 文献情報：
  Harrigan JA et al. Replication stress induces 53BP1-containing OPT domains in G1 cells. J. Cell Biol. 2011 Apr;193(1):97-108
  Harrigan JA et al
  2011/01/01
  
• 備考：
  
• 参照：
  

• No.： 18
• 文献情報：
  Konishi A et al. Cell cycle control of telomere protection and NHEJ revealed by a ts mutation in the DNA-binding domain of TRF2. Genes Dev. 2008 May;22(9):1221-30
  Konishi A et al
  2008/01/01
  
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• 参照：
  

• No.： 19
• 文献情報：
  Zhang W et al. DNA damage response is suppressed by the high cyclin-dependent kinase 1 activity in mitotic mammalian cells. J. Biol. Chem. 2011 Oct;286(41):35899-905
  Zhang W et al
  2011/01/01
  
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• 参照：
  

• No.： 20
• 文献情報：
  Brouwer AK et al. Telomeric DNA mediates de novo PML body formation. Mol. Biol. Cell 2009 Nov;20(22):4804-15
  Brouwer AK et al
  2009/01/01
  
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• 参照：
  

• No.： 21
• 文献情報：
  Denchi EL et al. Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1. Nature 2007 Aug;448(7157):1068-71
  Denchi EL et al
  2007/01/01
  
• 備考：
  
• 参照：
  

• No.： 22
• 文献情報：
  Kibe T et al. Telomere protection by TPP1 is mediated by POT1a and POT1b. Mol. Cell. Biol. 2010 Feb;30(4):1059-66
  Kibe T et al
  2010/01/01
  
• 備考：
  
• 参照：
  

• No.： 23
• 文献情報：
  Sheppard SA et al. LIM-domain proteins TRIP6 and LPP associate with shelterin to mediate telomere protection. Aging (Albany NY) 2010 Jul;2(7):432-44
  Sheppard SA et al
  2010/01/01
  
• 備考：
  
• 参照：
  

• No.： 24
• 文献情報：
  Westin ER et al. The p53/p21(WAF/CIP) pathway mediates oxidative stress and senescence in dyskeratosis congenita cells with telomerase insufficiency. Antioxid. Redox Signal. 2011 Mar;14(6):985-97
  Westin ER et al
  2011/01/01
  
• 備考：
  Applications: ICC, Species: Human
• 参照：
  

• No.： 25
• 文献情報：
  Reichert S et al. Survivin inhibition and DNA double-strand break repair: a molecular mechanism to overcome radioresistance in glioblastoma. Radiother Oncol 2011 Oct;101(1):51-8
  Reichert S et al
  2011/01/01
  
• 備考：
  Applications: WB, ICC, IF, Species: Human
• 参照：
  

• No.： 26
• 文献情報：
  Kibe R et al. IL-7R&#x3B1; deficiency in p53null mice exacerbates thymocyte telomere erosion and lymphomagenesis. Cell Death Differ. 2012 Jul;19(7):1139-51
  Kibe R et al
  2012/01/01
  
• 備考：
  Applications: IF, Species: Mouse
• 参照：
  

• No.： 27
• 文献情報：
  Grenier L et al. The activation of DNA damage detection and repair responses in cleavage-stage rat embryos by a damaged paternal genome. Toxicol. Sci. 2012 Jun;127(2):555-66
  Grenier L et al
  2012/01/01
  
• 備考：
  Applications: IF, Species: Rat
• 参照：
  

• No.： 28
• 文献情報：
  Luijsterburg MS et al. A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure. EMBO J. 2012 May;31(11):2511-27
  Luijsterburg MS et al
  2012/01/01
  
• 備考：
  Applications: ICC, IF, Species: Mouse
• 参照：
  

• No.： 29
• 文献情報：
  Suram A et al. Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions. EMBO J. 2012;31(13):2839-51
  Suram A et al
  2012/01/01
  
• 備考：
  Applications: IHC, IF, Species: Human
• 参照：
  

• No.： 30
• 文献情報：
  Wong V et al. Metabolism of Cr(VI) by ascorbate but not glutathione is a low oxidant-generating process. J Trace Elem Med Biol 2012 Jun;26(2-3):192-6
  Wong V et al
  2012/01/01
  
• 備考：
  Applications: ICC, IF, Species: Human
• 参照：
  

• No.： 31
• 文献情報：
  Pont AR et al. mRNA Decay Factor AUF1 Maintains Normal Aging, Telomere Maintenance, and Suppression of Senescence by Activation of Telomerase Transcription. Mol. Cell 2012 Jul;47(1):5-15
  Pont AR et al
  2012/01/01
  
• 備考：
  Applications: ICC, IF, Species: Mouse
• 参照：
  

• No.： 32
• 文献情報：
  Francia S et al. Site-specific DICER and DROSHA RNA products control the DNA-damage response. Nature 2012 Aug;488(7410):231-5
  Francia S et al
  2012/01/01
  
• 備考：
  Applications: ICC, IF, Species: Human, Mouse
• 参照：
  

• No.： 33
• 文献情報：
  Bolderson E et al. Kruppel-associated Box (KRAB)-associated co-repressor (KAP-1) Ser-473 phosphorylation regulates heterochromatin protein 1&#x3B2; (HP1-&#x3B2;) mobilization and DNA repair in heterochromatin. J. Biol. Chem. 2012 Aug;287(33):28122-31
  Bolderson E et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 34
• 文献情報：
  Sato Y et al. Molecular basis of Lys-63-linked polyubiquitination inhibition by the interaction between human deubiquitinating enzyme OTUB1 and ubiquitin-conjugating enzyme UBC13. J. Biol. Chem. 2012 Jul;287(31):25860-8
  Sato Y et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 35
• 文献情報：
  Nishimaki N et al. Autocrine regulation of &#x3B3;-irradiation-induced DNA damage response via extracellular nucleotides-mediated activation of P2Y6 and P2Y12 receptors. DNA Repair (Amst.) 2012 Aug;11(8):657-65
  Nishimaki N et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ICC, IF
• 参照：
  

• No.： 36
• 文献情報：
  Lovejoy CA et al. Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway. PLoS Genet 2012 Jul;8(7):e1002772
  Lovejoy CA et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 37
• 文献情報：
  Eke I et al. Three-dimensional Invasion of Human Glioblastoma Cells Remains Unchanged by X-ray and Carbon Ion Irradiation In Vitro. Int. J. Radiat. Oncol. Biol. Phys. 2012 Aug;
  Eke I et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 38
• 文献情報：
  Galron R et al. Astrocyte dysfunction associated with cerebellar attrition in a Nijmegen breakage syndrome animal model. J. Mol. Neurosci. 2011 Oct;45(2):202-11
  Galron R et al
  2011/01/01
  
• 備考：
  Species: Mouse, Applications: IHC, IF
• 参照：
  

• No.： 39
• 文献情報：
  Davoli T et al. Telomere-driven tetraploidization occurs in human cells undergoing crisis and promotes transformation of mouse cells. Cancer Cell 2012 Jun;21(6):765-76
  Davoli T et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ICC, IF
• 参照：
  

• No.： 40
• 文献情報：
  Eke I et al. Enhanced radiosensitivity of head and neck squamous cell carcinoma cells by &#x3B2;1 integrin inhibition. Radiother Oncol 2012 Aug;104(2):235-42
  Eke I et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ICC, IF
• 参照：
  

• No.： 41
• 文献情報：
  Wilsker D et al. Chk1 suppresses bypass of mitosis and tetraploidization in p53-deficient cancer cells. Cell Cycle 2012 Apr;11(8):1564-72
  Wilsker D et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: WB, ICC/IF
• 参照：
  

• No.： 42
• 文献情報：
  Pires IM et al. Targeting radiation-resistant hypoxic tumour cells through ATR inhibition. Br. J. Cancer 2012 Jul;107(2):291-9
  Pires IM et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ICC, IF
• 参照：
  

• No.： 43
• 文献情報：
  Trainor C et al. DNA Damage Responses following Exposure to Modulated Radiation Fields. PLoS ONE 2012;7(8):e43326
  Trainor C et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 44
• 文献情報：
  Bosco N et al. A TRF1-controlled common fragile site containing interstitial telomeric sequences. Chromosoma 2012 Oct;121(5):465-74
  Bosco N et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 45
• 文献情報：
  Laschinsky L et al. Radiobiological effectiveness of laser accelerated electrons in comparison to electron beams from a conventional linear accelerator. J. Radiat. Res. 2012;53(3):395-403
  Laschinsky L et al
  2012/01/01
  
• 備考：
  Applications: ICC/IF
• 参照：
  

• No.： 46
• 文献情報：
  Viana-Pereira M et al. Microsatellite instability in pediatric high grade glioma is associated with genomic profile and differential target gene inactivation. PLoS ONE 2011;6(5):e20588
  Viana-Pereira M et al
  2011/01/01
  
• 備考：
  Applications: ICC/IF
• 参照：
  

• No.： 47
• 文献情報：
  Mund A et al. SPOC1 modulates DNA repair by regulating key determinants of chromatin compaction and DNA damage response. Nucleic Acids Res. 2012 Oct;
  Mund A et al
  2012/01/01
  
• 備考：
  Applications: ICC/IF
• 参照：
  

• No.： 48
• 文献情報：
  Popova T et al. Ploidy and Large-Scale Genomic Instability Consistently Identify Basal-like Breast Carcinomas with BRCA1/2 Inactivation. Cancer Res. 2012 Nov;72(21):5454-62
  Popova T et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 49
• 文献情報：
  Korwek Z et al. Inhibition of ATM blocks the etoposide-induced DNA damage response and apoptosis of resting human T cells. DNA Repair (Amst.) 2012 Nov;11(11):864-73
  Korwek Z et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 50
• 文献情報：
  Squatrito M et al. 53BP1 is a haploinsufficient tumor suppressor and protects cells from radiation response in glioma. Cancer Res. 2012 Oct;72(20):5250-60
  Squatrito M et al
  2012/01/01
  
• 備考：
  Species: Mouse, Applications: IHC
• 参照：
  

• No.： 51
• 文献情報：
  Nandakumar J et al. The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity. Nature 2012 Oct;
  Nandakumar J et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 52
• 文献情報：
  Fink LS et al. 53BP1 contributes to a robust genomic stability in human fibroblasts. Aging (Albany NY) 2011 Sep;3(9):836-45
  Fink LS et al
  2011/01/01
  
• 備考：
  
• 参照：
  

• No.： 53
• 文献情報：
  B旦hringer M et al. siRNA screening identifies differences in the Fanconi anemia pathway in BALB/c-Trp53+/- with susceptibility versus C57BL/6-Trp53+/- mice with resistance to mammary tumors. Oncogene 2013 Feb;
  B旦hringer M et al
  2013/01/01
  
• 備考：
  Species: Mouse, Applications: ICC/IF
• 参照：
  

• No.： 54
• 文献情報：
  Popuri V et al. RECQ1 is required for cellular resistance to replication stress and catalyzes strand exchange on stalled replication fork structures. Cell Cycle 2012 Nov;11(22):4252-65
  Popuri V et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 55
• 文献情報：
  Ziebarth AJ et al. Endoglin (CD105) contributes to platinum resistance and is a target for tumor-specific therapy in epithelial ovarian cancer. Clin. Cancer Res. 2013 Jan;19(1):170-82
  Ziebarth AJ et al
  2013/01/01
  
• 備考：
  Species: Mouse, Applications: IHC, ICC/IF
• 参照：
  

• No.： 56
• 文献情報：
  Mokrani-Benhelli H et al. Primary microcephaly, impaired DNA replication, and genomic instability caused by compound heterozygous ATR mutations. Hum. Mutat. 2013 Feb;34(2):374-84
  Mokrani-Benhelli H et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 57
• 文献情報：
  Korwek Z et al. DNA damage-independent apoptosis induced by curcumin in normal resting human T cells and leukaemic Jurkat cells. Mutagenesis 2013 Mar;
  Korwek Z et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 58
• 文献情報：
  Sotiropoulou PA et al. BRCA1 deficiency in skin epidermis leads to selective loss of hair follicle stem cells and their progeny. Genes Dev. 2013 Jan;27(1):39-51
  Sotiropoulou PA et al
  2013/01/01
  
• 備考：
  Species: Mouse, Applications: IHC, ICC/IF
• 参照：
  

• No.： 59
• 文献情報：
  Grotsky DA et al. BRCA1 loss activates cathepsin L-mediated degradation of 53BP1 in breast cancer cells. J. Cell Biol. 2013 Jan;200(2):187-202
  Grotsky DA et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: WB, ICC/IF, IHC-P
• 参照：
  

• No.： 60
• 文献情報：
  Berti M et al. Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition. Nat. Struct. Mol. Biol. 2013 Mar;20(3):347-54
  Berti M et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 61
• 文献情報：
  Courilleau C et al. The chromatin remodeler p400 ATPase facilitates Rad51-mediated repair of DNA double-strand breaks. J. Cell Biol. 2012 Dec;199(7):1067-81
  Courilleau C et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 62
• 文献情報：
  Caretti V et al. WEE1 kinase inhibition enhances the radiation response of diffuse intrinsic pontine gliomas. Mol. Cancer Ther. 2013 Feb;12(2):141-50
  Caretti V et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 63
• 文献情報：
  Mirza S et al. Alteration/deficiency in activation-3 (Ada3) plays a critical role in maintaining genomic stability. Cell Cycle 2012 Nov;11(22):4266-74
  Mirza S et al
  2012/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 64
• 文献情報：
  Jeyapalan JC et al. How to measure RNA expression in rare senescent cells expressing any specific protein such as p16Ink4a. Aging (Albany NY) 2013 Feb;5(2):120-9
  Jeyapalan JC et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 65
• 文献情報：
  Hartlerode AJ et al. Impact of histone H4 lysine 20 methylation on 53BP1 responses to chromosomal double strand breaks. PLoS ONE 2012;7(11):e49211
  Hartlerode AJ et al
  2012/01/01
  
• 備考：
  Species: Mouse, Applications: ICC/IF
• 参照：
  

• No.： 66
• 文献情報：
  Dreesen O et al. Lamin B1 fluctuations have differential effects on cellular proliferation and senescence. J. Cell Biol. 2013 Mar;200(5):605-17
  Dreesen O et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 67
• 文献情報：
  Stout GJ et al. Telomere Length and Telomerase Activity Impact the UV Sensitivity Syndrome Xeroderma Pigmentosum C. Cancer Res. 2013 Mar;73(6):1844-54
  Stout GJ et al
  2013/01/01
  
• 備考：
  Species: Mouse
• 参照：
  

• No.： 68
• 文献情報：
  Okamoto K et al. A two-step mechanism for TRF2-mediated chromosome-end protection. Nature 2013 Feb;494(7438):502-5
  Okamoto K et al
  2013/01/01
  
• 備考：
  Species: Mouse, Applications: ICC/IF
• 参照：
  

• No.： 69
• 文献情報：
  Pei H et al. The histone methyltransferase MMSET regulates class switch recombination. J. Immunol. 2013 Jan;190(2):756-63
  Pei H et al
  2013/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 70
• 文献情報：
  Suberbielle E et al. Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-&#x3B2;. Nat. Neurosci. 2013 May;16(5):613-21
  Suberbielle E et al
  2013/01/01
  
• 備考：
  Species: Mouse, Applications: ICC/IF
• 参照：
  

• No.： 71
• 文献情報：
  Ausborn NL et al. 53BP1 expression is a modifier of the prognostic value of lymph node ratio and CA 19-9 in pancreatic adenocarcinoma. BMC Cancer 2013;13:155
  Ausborn NL et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: IHC-P
• 参照：
  

• No.： 72
• 文献情報：
  Grosso S et al. MiR-210 promotes a hypoxic phenotype and increases radioresistance in human lung cancer cell lines. Cell Death Dis 2013;4:e544
  Grosso S et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

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