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在庫・価格 : 2024年05月01日 07時16分 現在

商品名 商品コード メーカー 包装 価格 在庫 リスト
Anti-HIF Prolyl Hydroxylase 3, Rabbit-Poly <Anti-PHD3> <Anti-EGLN3>
データシート
NB100-303 NOVノバス バイオロジカルス
Novus biologicals, LLC
100 μl ¥91,000
(未発注)
追加

在庫・価格 : 2024年05月01日 07時16分 現在

Anti-HIF Prolyl Hydroxylase 3, Rabbit-Poly <Anti-PHD3> <Anti-EGLN3>

  • 商品コード:NB100-303
  • メーカー:NOV
  • 包装:100μl
  • 価格: ¥91,000
  • 在庫:無(未発注)
使用文献
No. 文献情報 備考 参照
1 Baek JH et al. OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha. Mol. Cell 2005 Feb;17(4):503-12
Baek JH et al
2005/01/01
PubMed
2 Ietta F et al. Dynamic HIF1A regulation during human placental development. Biol. Reprod. 2006 Jul;75(1):112-21
Ietta F et al
2006/01/01
PubMed
3 Mikhaylova O et al. The von Hippel-Lindau tumor suppressor protein and Egl-9-Type proline hydroxylases regulate the large subunit of RNA polymerase II in response to oxidative stress. Mol. Cell. Biol. 2008 Apr;28(8):2701-17
Mikhaylova O et al
2008/01/01
PubMed
4 Michailidou Z et al. Increased angiogenesis protects against adipose hypoxia and fibrosis in metabolic disease-resistant 11&#x3B2;-hydroxysteroid dehydrogenase type 1 (HSD1)-deficient mice. J. Biol. Chem. 2012 Feb;287(6):4188-97
Michailidou Z et al
2012/01/01
PubMed
5 Sch旦del J et al. HIF-prolyl hydroxylases in the rat kidney: physiologic expression patterns and regulation in acute kidney injury. Am. J. Pathol. 2009 May;174(5):1663-74
Sch旦del J et al
2009/01/01
PubMed
6 Rodr鱈guez-Jim辿nez FJ et al. Hypoxia causes downregulation of mismatch repair system and genomic instability in stem cells. Stem Cells 2008 Aug;26(8):2052-62
Rodr鱈guez-Jim辿nez FJ et al
2008/01/01
PubMed
7 Minamishima YA et al. A feedback loop involving the Phd3 prolyl hydroxylase tunes the mammalian hypoxic response in vivo. Mol. Cell. Biol. 2009 Nov;29(21):5729-41
Minamishima YA et al
2009/01/01
PubMed
8 Minamishima YA et al. Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure. Blood 2008 Mar;111(6):3236-44
Minamishima YA et al
2008/01/01
PubMed
9 Yan B et al. Prolyl hydroxylase domain protein 3 targets Pax2 for destruction. Biochem. Biophys. Res. Commun. 2011 Jun;409(2):315-20
Yan B et al
2011/01/01
PubMed
10 Tang X et al. Functional interaction between responses to lactic acidosis and hypoxia regulates genomic transcriptional outputs. Cancer Res. 2012 Jan;72(2):491-502
Tang X et al
2012/01/01
PubMed
11 Takeda K et al. Regulation of adult erythropoiesis by prolyl hydroxylase domain proteins. Blood 2008 Mar;111(6):3229-35
Takeda K et al
2008/01/01
PubMed
12 Rabie T et al. Impaired hypoxic response in senescent mouse brain. Int. J. Dev. Neurosci. 2011 Oct;29(6):655-61
Rabie T et al
2011/01/01
PubMed
13 Luo W et al. Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1. Cell 2011 May;145(5):732-44
Luo W et al
2011/01/01
Applications: ChIP, WB, Species: Human PubMed
14 Gal叩n-Cobo A et al. Cellular overexpression of aquaporins slows down the natural HIF-2&#x3B1; degradation during prolonged hypoxia. Gene 2013 Jun;522(1):18-26
Gal叩n-Cobo A et al
2013/01/01
Species: Rat, Applications: WB PubMed
15 Rajakumar A et al. Proteasomal activity in placentas from women with preeclampsia and intrauterine growth restriction: implications for expression of HIF-alpha proteins. Placenta 2008 Mar;29(3):290-9
Rajakumar A et al
2008/01/01
Species: Human, Applications: WB PubMed
16 Fu J et al. EGLN3 Inhibition of NF-&#x3BA;B Is Mediated by Prolyl Hydroxylase-Independent Inhibition of I&#x3BA;B Kinase &#x3B3; Ubiquitination. Mol. Cell. Biol. 2013 Aug;33(15):3050-61
Fu J et al
2013/01/01
Species: Human, Primate, Applications: WB PubMed
17 Wiley M et al. Toxoplasma gondii activates hypoxia-inducible factor (HIF) by stabilizing the HIF-1alpha subunit via type I activin-like receptor kinase receptor signaling. J. Biol. Chem. 2010 Aug;285(35):26852-60
Wiley M et al
2010/01/01
Species: Human, Applications: WB PubMed
18 Tan JT et al. High-density lipoproteins augment hypoxia-induced angiogenesis via regulation of post-translational modulation of hypoxia-inducible factor 1&#x3B1;. FASEB J. 2014 Jan;28(1):206-17
Tan JT et al
2014/01/01
Species: Human, Applications: WB PubMed
19 Cervera AM et al. An alternatively spliced transcript of the PHD3 gene retains prolyl hydroxylase activity. Cancer Lett. 2006 Feb;233(1):131-8
Cervera AM et al
2006/01/01
PubMed
20 Kim J et al. The Role of Prolyl Hydroxylase Domain Protein (PHD) during Rosiglitazone-induced Adipocyte Differentiation. J. Biol. Chem. 2014 Jan;289(5):2755-64
Kim J et al
2014/01/01
PubMed
21 Lindholm ME et al. Negative regulation of HIF in skeletal muscle of elite endurance athletes: a tentative mechanism promoting oxidative metabolism. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2014 Aug;307(3):R248-55
Lindholm ME et al
2014/01/01
Species: Human, Applications: WB PubMed
22 Reischl S et al. Inhibition of HIF prolyl-4-hydroxylases by FG-4497 reduces brain tissue injury and edema formation during ischemic stroke. PLoS ONE 2014;9(1):e84767
Reischl S et al
2014/01/01
Species: Mouse, Applications: WB PubMed
23 Henze AT et al. Loss of PHD3 allows tumours to overcome hypoxic growth inhibition and sustain proliferation through EGFR. Nat Commun 2014;5:5582
Henze AT et al
2014/01/01
PubMed
24 Garvalov BK et al. PHD3 regulates EGFR internalization and signalling in tumours. Nat Commun 2014;5:5577
Garvalov BK et al
2014/01/01
Species: Human, Applications: WB PubMed
25 Kim M et al. ER&#x3B1; upregulates Phd3 to ameliorate HIF-1 induced fibrosis and inflammation in adipose tissue. Mol Metab 2014 Sep;3(6):642-51
Kim M et al
2014/01/01
Species: Mouse, Applications: IHC-P PubMed
26 Swain L et al. Prolyl-4-hydroxylase domain 3 (PHD3) is a critical terminator for cell survival of macrophages under stress conditions. J. Leukoc. Biol. 2014 Sep;96(3):365-75
Swain L et al
2014/01/01
Species: Mouse, PubMed
27 Luo T et al. Molecular characterization of antibody epitopes of Ehrlichia chaffeensis ankyrin protein 200 and tandem repeat protein 47 and evaluation of synthetic immunodeterminants for serodiagnosis of human monocytotropic ehrlichiosis. Clin. Vaccine Imm
Luo T et al
2010/01/01
Applications: WB PubMed
28 Vogel S et al. Prolyl hydroxylase domain (PHD) 2 affects cell migration and F-actin formation via RhoA/rho-associated kinase-dependent cofilin phosphorylation. J. Biol. Chem. 2010 Oct;285(44):33756-63
Vogel S et al
2010/01/01
Species: Human, Applications: ICC/IF PubMed
29 Zieseniss A et al. Cardiomyocyte-Specific Transgenic Expression of Prolyl-4-Hydroxylase Domain 3 Impairs the Myocardial Response to Ischemia. Cell. Physiol. Biochem. 2015;36(3):843-51
Zieseniss A et al
2015/01/01
PubMed
30 Kunze R et al. Neuron-specific prolyl-4-hydroxylase domain 2 knockout reduces brain injury after transient cerebral ischemia. Stroke 2012 Oct;43(10):2748-56
Kunze R et al
2012/01/01
PubMed
31 Gibier JB et al. Dual role of MUC1 mucin in kidney ischemia-reperfusion injury: Nephroprotector in early phase, but pro-fibrotic in late phase. Biochim Biophys Acta Mol Basis Dis 2017 06;1863(6):1336-1349
Gibier JB et al
2017/01/01
IB PubMed
32 Sim J et al. The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia. Cell Metab. 2018 Apr;27(4):898-913.e7
Sim J et al
2018/01/01
Species: Mouse, Applications: WB PubMed
33 Shin J et al. Prolyl hydroxylase domain 2 deficiency promotes skeletal muscle fiber-type transition via a calcineurin/NFATc1-dependent pathway. Skelet Muscle 2016;6:5
Shin J et al
2016/01/01
WB PubMed
34 Tan JT et al. High-Density Lipoproteins Rescue Diabetes-Impaired Angiogenesis via Scavenger Receptor Class B Type I. Diabetes 2016 10;65(10):3091-103
Tan JT et al
2016/01/01
PubMed
35 Heir P et al. Oxygen-dependent Regulation of Erythropoietin Receptor Turnover and Signaling. J. Biol. Chem. 2016 Apr;291(14):7357-72
Heir P et al
2016/01/01
PubMed
36 Xu YM et al. Prolyl hydroxylase 3 controls the intestine goblet cell generation through stabilizing ATOH1. Cell Death Differ 2020 07;27(7):2131-2142
Xu YM et al
2020/01/01
PubMed
37 Pastor-Soler NM et al. Muc1 is protective during kidney ischemia-reperfusion injury. Am J Physiol Renal Physiol 2015 Jun;308(12):F1452-62
Pastor-Soler NM et al
2015/01/01
PubMed
  • No.: 1
  • 文献情報:
    Baek JH et al. OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha. Mol. Cell 2005 Feb;17(4):503-12
    Baek JH et al
    2005/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 2
  • 文献情報:
    Ietta F et al. Dynamic HIF1A regulation during human placental development. Biol. Reprod. 2006 Jul;75(1):112-21
    Ietta F et al
    2006/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 3
  • 文献情報:
    Mikhaylova O et al. The von Hippel-Lindau tumor suppressor protein and Egl-9-Type proline hydroxylases regulate the large subunit of RNA polymerase II in response to oxidative stress. Mol. Cell. Biol. 2008 Apr;28(8):2701-17
    Mikhaylova O et al
    2008/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 4
  • 文献情報:
    Michailidou Z et al. Increased angiogenesis protects against adipose hypoxia and fibrosis in metabolic disease-resistant 11&#x3B2;-hydroxysteroid dehydrogenase type 1 (HSD1)-deficient mice. J. Biol. Chem. 2012 Feb;287(6):4188-97
    Michailidou Z et al
    2012/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 5
  • 文献情報:
    Sch旦del J et al. HIF-prolyl hydroxylases in the rat kidney: physiologic expression patterns and regulation in acute kidney injury. Am. J. Pathol. 2009 May;174(5):1663-74
    Sch旦del J et al
    2009/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 6
  • 文献情報:
    Rodr鱈guez-Jim辿nez FJ et al. Hypoxia causes downregulation of mismatch repair system and genomic instability in stem cells. Stem Cells 2008 Aug;26(8):2052-62
    Rodr鱈guez-Jim辿nez FJ et al
    2008/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 7
  • 文献情報:
    Minamishima YA et al. A feedback loop involving the Phd3 prolyl hydroxylase tunes the mammalian hypoxic response in vivo. Mol. Cell. Biol. 2009 Nov;29(21):5729-41
    Minamishima YA et al
    2009/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 8
  • 文献情報:
    Minamishima YA et al. Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure. Blood 2008 Mar;111(6):3236-44
    Minamishima YA et al
    2008/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 9
  • 文献情報:
    Yan B et al. Prolyl hydroxylase domain protein 3 targets Pax2 for destruction. Biochem. Biophys. Res. Commun. 2011 Jun;409(2):315-20
    Yan B et al
    2011/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 10
  • 文献情報:
    Tang X et al. Functional interaction between responses to lactic acidosis and hypoxia regulates genomic transcriptional outputs. Cancer Res. 2012 Jan;72(2):491-502
    Tang X et al
    2012/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 11
  • 文献情報:
    Takeda K et al. Regulation of adult erythropoiesis by prolyl hydroxylase domain proteins. Blood 2008 Mar;111(6):3229-35
    Takeda K et al
    2008/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 12
  • 文献情報:
    Rabie T et al. Impaired hypoxic response in senescent mouse brain. Int. J. Dev. Neurosci. 2011 Oct;29(6):655-61
    Rabie T et al
    2011/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 13
  • 文献情報:
    Luo W et al. Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1. Cell 2011 May;145(5):732-44
    Luo W et al
    2011/01/01
  • 備考:
    Applications: ChIP, WB, Species: Human
  • 参照:
    PubMed
  • No.: 14
  • 文献情報:
    Gal叩n-Cobo A et al. Cellular overexpression of aquaporins slows down the natural HIF-2&#x3B1; degradation during prolonged hypoxia. Gene 2013 Jun;522(1):18-26
    Gal叩n-Cobo A et al
    2013/01/01
  • 備考:
    Species: Rat, Applications: WB
  • 参照:
    PubMed
  • No.: 15
  • 文献情報:
    Rajakumar A et al. Proteasomal activity in placentas from women with preeclampsia and intrauterine growth restriction: implications for expression of HIF-alpha proteins. Placenta 2008 Mar;29(3):290-9
    Rajakumar A et al
    2008/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 16
  • 文献情報:
    Fu J et al. EGLN3 Inhibition of NF-&#x3BA;B Is Mediated by Prolyl Hydroxylase-Independent Inhibition of I&#x3BA;B Kinase &#x3B3; Ubiquitination. Mol. Cell. Biol. 2013 Aug;33(15):3050-61
    Fu J et al
    2013/01/01
  • 備考:
    Species: Human, Primate, Applications: WB
  • 参照:
    PubMed
  • No.: 17
  • 文献情報:
    Wiley M et al. Toxoplasma gondii activates hypoxia-inducible factor (HIF) by stabilizing the HIF-1alpha subunit via type I activin-like receptor kinase receptor signaling. J. Biol. Chem. 2010 Aug;285(35):26852-60
    Wiley M et al
    2010/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 18
  • 文献情報:
    Tan JT et al. High-density lipoproteins augment hypoxia-induced angiogenesis via regulation of post-translational modulation of hypoxia-inducible factor 1&#x3B1;. FASEB J. 2014 Jan;28(1):206-17
    Tan JT et al
    2014/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 19
  • 文献情報:
    Cervera AM et al. An alternatively spliced transcript of the PHD3 gene retains prolyl hydroxylase activity. Cancer Lett. 2006 Feb;233(1):131-8
    Cervera AM et al
    2006/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 20
  • 文献情報:
    Kim J et al. The Role of Prolyl Hydroxylase Domain Protein (PHD) during Rosiglitazone-induced Adipocyte Differentiation. J. Biol. Chem. 2014 Jan;289(5):2755-64
    Kim J et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 21
  • 文献情報:
    Lindholm ME et al. Negative regulation of HIF in skeletal muscle of elite endurance athletes: a tentative mechanism promoting oxidative metabolism. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2014 Aug;307(3):R248-55
    Lindholm ME et al
    2014/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 22
  • 文献情報:
    Reischl S et al. Inhibition of HIF prolyl-4-hydroxylases by FG-4497 reduces brain tissue injury and edema formation during ischemic stroke. PLoS ONE 2014;9(1):e84767
    Reischl S et al
    2014/01/01
  • 備考:
    Species: Mouse, Applications: WB
  • 参照:
    PubMed
  • No.: 23
  • 文献情報:
    Henze AT et al. Loss of PHD3 allows tumours to overcome hypoxic growth inhibition and sustain proliferation through EGFR. Nat Commun 2014;5:5582
    Henze AT et al
    2014/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 24
  • 文献情報:
    Garvalov BK et al. PHD3 regulates EGFR internalization and signalling in tumours. Nat Commun 2014;5:5577
    Garvalov BK et al
    2014/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 25
  • 文献情報:
    Kim M et al. ER&#x3B1; upregulates Phd3 to ameliorate HIF-1 induced fibrosis and inflammation in adipose tissue. Mol Metab 2014 Sep;3(6):642-51
    Kim M et al
    2014/01/01
  • 備考:
    Species: Mouse, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 26
  • 文献情報:
    Swain L et al. Prolyl-4-hydroxylase domain 3 (PHD3) is a critical terminator for cell survival of macrophages under stress conditions. J. Leukoc. Biol. 2014 Sep;96(3):365-75
    Swain L et al
    2014/01/01
  • 備考:
    Species: Mouse,
  • 参照:
    PubMed
  • No.: 27
  • 文献情報:
    Luo T et al. Molecular characterization of antibody epitopes of Ehrlichia chaffeensis ankyrin protein 200 and tandem repeat protein 47 and evaluation of synthetic immunodeterminants for serodiagnosis of human monocytotropic ehrlichiosis. Clin. Vaccine Imm
    Luo T et al
    2010/01/01
  • 備考:
    Applications: WB
  • 参照:
    PubMed
  • No.: 28
  • 文献情報:
    Vogel S et al. Prolyl hydroxylase domain (PHD) 2 affects cell migration and F-actin formation via RhoA/rho-associated kinase-dependent cofilin phosphorylation. J. Biol. Chem. 2010 Oct;285(44):33756-63
    Vogel S et al
    2010/01/01
  • 備考:
    Species: Human, Applications: ICC/IF
  • 参照:
    PubMed
  • No.: 29
  • 文献情報:
    Zieseniss A et al. Cardiomyocyte-Specific Transgenic Expression of Prolyl-4-Hydroxylase Domain 3 Impairs the Myocardial Response to Ischemia. Cell. Physiol. Biochem. 2015;36(3):843-51
    Zieseniss A et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 30
  • 文献情報:
    Kunze R et al. Neuron-specific prolyl-4-hydroxylase domain 2 knockout reduces brain injury after transient cerebral ischemia. Stroke 2012 Oct;43(10):2748-56
    Kunze R et al
    2012/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 31
  • 文献情報:
    Gibier JB et al. Dual role of MUC1 mucin in kidney ischemia-reperfusion injury: Nephroprotector in early phase, but pro-fibrotic in late phase. Biochim Biophys Acta Mol Basis Dis 2017 06;1863(6):1336-1349
    Gibier JB et al
    2017/01/01
  • 備考:
    IB
  • 参照:
    PubMed
  • No.: 32
  • 文献情報:
    Sim J et al. The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia. Cell Metab. 2018 Apr;27(4):898-913.e7
    Sim J et al
    2018/01/01
  • 備考:
    Species: Mouse, Applications: WB
  • 参照:
    PubMed
  • No.: 33
  • 文献情報:
    Shin J et al. Prolyl hydroxylase domain 2 deficiency promotes skeletal muscle fiber-type transition via a calcineurin/NFATc1-dependent pathway. Skelet Muscle 2016;6:5
    Shin J et al
    2016/01/01
  • 備考:
    WB
  • 参照:
    PubMed
  • No.: 34
  • 文献情報:
    Tan JT et al. High-Density Lipoproteins Rescue Diabetes-Impaired Angiogenesis via Scavenger Receptor Class B Type I. Diabetes 2016 10;65(10):3091-103
    Tan JT et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 35
  • 文献情報:
    Heir P et al. Oxygen-dependent Regulation of Erythropoietin Receptor Turnover and Signaling. J. Biol. Chem. 2016 Apr;291(14):7357-72
    Heir P et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 36
  • 文献情報:
    Xu YM et al. Prolyl hydroxylase 3 controls the intestine goblet cell generation through stabilizing ATOH1. Cell Death Differ 2020 07;27(7):2131-2142
    Xu YM et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 37
  • 文献情報:
    Pastor-Soler NM et al. Muc1 is protective during kidney ischemia-reperfusion injury. Am J Physiol Renal Physiol 2015 Jun;308(12):F1452-62
    Pastor-Soler NM et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed