Anti-IRE1α(pSer724), Phosphorylated, Rabbit-Poly

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• 商品コード：NB100-2323
• メーカー：NOV
• 包装：0.1ml
• 価格： ¥103,000
• 在庫：1個

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• No.： 1
• 文献情報：
  Lipson KL et al. Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1. Cell Metab. 2006 Sep;4(3):245-54
  Lipson KL et al
  2006/01/01
  
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• No.： 2
• 文献情報：
  Morcavallo A et al. Insulin and Insulin-like Growth Factor II Differentially Regulate Endocytic Sorting and Stability of Insulin Receptor Isoform A. J. Biol. Chem. 2012 Mar;287(14):11422-36
  Morcavallo A et al
  2012/01/01
  
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• No.： 3
• 文献情報：
  Shimada Y et al. Endoplasmic reticulum stress induces autophagy through activation of p38 MAPK in fibroblasts from Pompe disease patients carrying c.546G>T mutation. Mol. Genet. Metab. 2011 Dec;104(4):566-73
  Shimada Y et al
  2011/01/01
  
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• No.： 4
• 文献情報：
  Nijholt DA et al. The unfolded protein response is associated with early tau pathology in the hippocampus of tauopathies. J. Pathol. 2012 Apr;226(5):693-702
  Nijholt DA et al
  2012/01/01
  
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• No.： 5
• 文献情報：
  Chuang TC et al. Magnolol down-regulates HER2 gene expression, leading to inhibition of HER2-mediated metastatic potential in ovarian cancer cells. Cancer Lett. 2011 Dec;311(1):11-9
  Chuang TC et al
  2011/01/01
  
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• No.： 6
• 文献情報：
  Hage Hassan R et al. Endoplasmic reticulum stress does not mediate palmitate-induced insulin resistance in mouse and human muscle cells. Diabetologia 2012 Jan;55(1):204-14
  Hage Hassan R et al
  2012/01/01
  
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• No.： 7
• 文献情報：
  Lim MP et al. Cannabidiol causes activated hepatic stellate cell death through a mechanism of endoplasmic reticulum stress-induced apoptosis. Cell Death Dis 2011;2:e170
  Lim MP et al
  2011/01/01
  
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• 参照：
  

• No.： 8
• 文献情報：
  Yamagishi N et al. Decreased expression of endoplasmic reticulum chaperone GRP78 in liver of diabetic mice. Biochem. Biophys. Res. Commun. 2012 Jan;417(1):364-70
  Yamagishi N et al
  2012/01/01
  
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• No.： 9
• 文献情報：
  Ota A et al. Cdc37/Hsp90 protein-mediated regulation of IRE1α protein activity in endoplasmic reticulum stress response and insulin synthesis in INS-1 cells. J. Biol. Chem. 2012 Feb;287(9):6266-74
  Ota A et al
  2012/01/01
  
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• No.： 10
• 文献情報：
  Castillo K et al. BAX inhibitor-1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response. EMBO J. 2011 Nov;30(21):4465-78
  Castillo K et al
  2011/01/01
  
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• 参照：
  

• No.： 11
• 文献情報：
  Michallet AS et al. Compromising the unfolded protein response induces autophagy-mediated cell death in multiple myeloma cells. PLoS ONE 2011;6(10):e25820
  Michallet AS et al
  2011/01/01
  
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• 参照：
  

• No.： 12
• 文献情報：
  Qiu Y et al. A crucial role for RACK1 in the regulation of glucose-stimulated IRE1alpha activation in pancreatic beta cells. Sci Signal 2010;3(106):ra7
  Qiu Y et al
  2010/01/01
  
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• 参照：
  

• No.： 13
• 文献情報：
  Hoozemans JJ et al. The unfolded protein response is activated in pretangle neurons in Alzheimer"s disease hippocampus. Am. J. Pathol. 2009 Apr;174(4):1241-51
  Hoozemans JJ et al
  2009/01/01
  
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• 参照：
  

• No.： 14
• 文献情報：
  Chiang CK et al. Endoplasmic reticulum stress implicated in the development of renal fibrosis. Mol. Med. 2011;17(11-12):1295-305
  Chiang CK et al
  2011/01/01
  
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• 参照：
  

• No.： 15
• 文献情報：
  Chen K et al. Overexpression of Insig-1 protects β cell against glucolipotoxicity via SREBP-1c. J. Biomed. Sci. 2011;18:57
  Chen K et al
  2011/01/01
  
• 備考：
  
• 参照：
  

• No.： 16
• 文献情報：
  Luo D et al. AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response. J. Biol. Chem. 2008 May;283(18):11905-12
  Luo D et al
  2008/01/01
  
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• 参照：
  

• No.： 17
• 文献情報：
  Sugeno N et al. Serine 129 phosphorylation of alpha-synuclein induces unfolded protein response-mediated cell death. J. Biol. Chem. 2008 Aug;283(34):23179-88
  Sugeno N et al
  2008/01/01
  
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• 参照：
  

• No.： 18
• 文献情報：
  Kashiwakura Y et al. Down-regulation of inhibition of differentiation-1 via activation of activating transcription factor 3 and Smad regulates REIC/Dickkopf-3-induced apoptosis. Cancer Res. 2008 Oct;68(20):8333-41
  Kashiwakura Y et al
  2008/01/01
  
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• 参照：
  

• No.： 19
• 文献情報：
  Wang CT et al. Inhibition of the unfolded protein response by ricin a-chain enhances its cytotoxicity in Mammalian cells. Toxins (Basel) 2011 May;3(5):453-68
  Wang CT et al
  2011/01/01
  
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• 参照：
  

• No.： 20
• 文献情報：
  Teodoro T et al. Pancreatic β-cells depend on basal expression of active ATF6α-p50 for cell survival even under nonstress conditions. Am. J. Physiol., Cell Physiol. 2012 Apr;302(7):C992-1003
  Teodoro T et al
  2012/01/01
  
• 備考：
  Applications: WB, Species: Human
• 参照：
  

• No.： 21
• 文献情報：
  Wu LL et al. Endoplasmic reticulum (ER) stress in cumulus-oocyte complexes impairs pentraxin-3 secretion, mitochondrial membrane potential (DeltaPsi m), and embryo development. Mol. Endocrinol. 2012 Apr;26(4):562-73
  Wu LL et al
  2012/01/01
  
• 備考：
  Applications: WB, Species: Mouse
• 参照：
  

• No.： 22
• 文献情報：
  Zheng M et al. Sensing endoplasmic reticulum stress by protein kinase RNA-like endoplasmic reticulum kinase promotes adaptive mitochondrial DNA biogenesis and cell survival via heme oxygenase-1/carbon monoxide activity. FASEB J. 2012 Jun;26(6):2558-68
  Zheng M et al
  2012/01/01
  
• 備考：
  Applications: WB, Species: Mouse
• 参照：
  

• No.： 23
• 文献情報：
  Ri M et al. Identification of Toyocamycin, an agent cytotoxic for multiple myeloma cells, as a potent inhibitor of ER stress-induced XBP1 mRNA splicing. Blood Cancer J 2012 Jul;2(7):e79
  Ri M et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 24
• 文献情報：
  Zheng X et al. Acute hypoxia induces apoptosis of pancreatic β-cell by activation of the unfolded protein response and upregulation of CHOP. Cell Death Dis 2012;3:e322
  Zheng X et al
  2012/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 25
• 文献情報：
  Toosi S et al. Vitiligo-Inducing Phenols Activate the Unfolded Protein Response in Melanocytes Resulting in Upregulation of IL6 and IL8. J Invest Dermatol 2012 Jun;
  Toosi S et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 26
• 文献情報：
  Chen K, Jin P, He H-H, et al. Overexpression of Insig-1 protects beta cell against glucolipotoxicity via SREBP-1c. J Biomed Sci;18(1):57. 2011 Aug 16.
  
  
• 備考：
  
• 参照：
  

• No.： 27
• 文献情報：
  Kimura K et al. Endoplasmic reticulum stress inhibits STAT3-dependent suppression of hepatic gluconeogenesis via dephosphorylation and deacetylation. Diabetes 2012 Jan;61(1):61-73
  Kimura K et al
  2012/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 28
• 文献情報：
  Arshad M et al. RNF13, a RING Finger Protein, Mediates Endoplasmic Reticulum Stress-induced Apoptosis through the Inositol-requiring Enzyme (IRE1α)/c-Jun NH2-terminal Kinase Pathway. J. Biol. Chem. 2013 Mar;288(12):8726-36
  Arshad M et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 29
• 文献情報：
  Zheng M et al. Curcumin induces apoptotic cell death of activated human CD4+ T cells via increasing endoplasmic reticulum stress and mitochondrial dysfunction. Int. Immunopharmacol. 2013 Mar;15(3):517-23
  Zheng M et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 30
• 文献情報：
  Makioka K et al. Involvement of endoplasmic reticulum stress defined by activated unfolded protein response in multiple system atrophy. J. Neurol. Sci. 2010 Oct;297(1-2):60-5
  Makioka K et al
  2010/01/01
  
• 備考：
  Species: Human, Applications: IHC
• 参照：
  

• No.： 31
• 文献情報：
  Han J et al. ER stress signalling through eIF2α and CHOP, but not IRE1α, attenuates adipogenesis in mice. Diabetologia 2013 Apr;56(4):911-24
  Han J et al
  2013/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 32
• 文献情報：
  Otoda T et al. Proteasome dysfunction mediates obesity-induced endoplasmic reticulum stress and insulin resistance in the liver. Diabetes 2013 Mar;62(3):811-24
  Otoda T et al
  2013/01/01
  
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• 参照：
  

• No.： 33
• 文献情報：
  Cha SI et al. Cleaved cytokeratin-18 is a mechanistically informative biomarker in idiopathic pulmonary fibrosis. Respir. Res. 2012;13:105
  Cha SI et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 34
• 文献情報：
  Bartolome A et al. Autophagy plays a protective role in endoplasmic reticulum stress-mediated pancreatic β cell death. Autophagy 2012 Dec;8(12):1757-68
  Bartolome A et al
  2012/01/01
  
• 備考：
  
• 参照：
  

• No.： 35
• 文献情報：
  Akiyama M et al. X-box binding protein 1 is essential for insulin regulation of pancreatic alpha cell function. Diabetes 2013 Mar;
  Akiyama M et al
  2013/01/01
  
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• 参照：
  

• No.： 36
• 文献情報：
  Song Y et al. Inhibition of x-box binding protein 1 reduces tunicamycin-induced apoptosis in aged murine macrophages. Aging Cell 2013 May;
  Song Y et al
  2013/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 37
• 文献情報：
  Koh HJ et al. Tribbles 3 mediates endoplasmic reticulum stress-induced insulin resistance in skeletal muscle. Nat Commun 2013;4:1871
  Koh HJ et al
  2013/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 38
• 文献情報：
  Chen K, Jin P, He H-H et al. Overexpression of Insig-1 protects beta cell against glucolipotoxicity via SREBP-1c. J Biomed Sci;18(1):57. 2011 Aug 16.
  
  
• 備考：
  
• 参照：
  

• No.： 39
• 文献情報：
  Kitai Y et al. Membrane lipid saturation activates IRE1α without inducing clustering. Genes Cells 2013 Sep;18(9):798-809
  Kitai Y et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 40
• 文献情報：
  Yang C et al. Pathological endoplasmic reticulum stress mediated by the IRE1 pathway contributes to pre-insulitic beta cell apoptosis in a virus-induced rat model of type 1 diabetes. Diabetologia 2013 Dec;56(12):2638-46
  Yang C et al
  2013/01/01
  
• 備考：
  Species: Rat, Applications: WB
• 参照：
  

• No.： 41
• 文献情報：
  Kujiraoka T et al. Hepatic extracellular signal-regulated kinase 2 suppresses endoplasmic reticulum stress and protects from oxidative stress and endothelial dysfunction. J Am Heart Assoc 2013 Aug;2(4):e000361
  Kujiraoka T et al
  2013/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 42
• 文献情報：
  Chen YC et al. Rutaecarpine analogues reduce lipid accumulation in adipocytes via inhibiting adipogenesis/lipogenesis with AMPK activation and UPR suppression. ACS Chem. Biol. 2013 Oct;8(10):2301-11
  Chen YC et al
  2013/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 43
• 文献情報：
  Matsumoto H et al. Selection of autophagy or apoptosis in cells exposed to ER-stress depends on ATF4 expression pattern with or without CHOP expression. Biol Open 2013;2(10):1084-90
  Matsumoto H et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 44
• 文献情報：
  Lu G, Ota A, Ren S et al. PPM1l encodes an inositol requiring-protein 1 (IRE1) specific phosphatase that regulates the functional outcome of the ER stress response . Molecular Metabolism. 2013 Aug (WB, Mouse)
  
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 45
• 文献情報：
  Stahl S et al. Cytomegalovirus downregulates IRE1 to repress the unfolded protein response. PLoS Pathog. 2013;9(8):e1003544
  Stahl S et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 46
• 文献情報：
  Omikorede O et al. ER stress in rodent islets of Langerhans is concomitant with obesity and β-cell compensation but not with β-cell dysfunction and diabetes. Nutr Diabetes 2013;3:e93
  Omikorede O et al
  2013/01/01
  
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• 参照：
  

• No.： 47
• 文献情報：
  Liu L et al. The Resveratrol Attenuates Ethanol-Induced Hepatocyte Apoptosis Via Inhibiting ER-Related Caspase-12 Activation and PDE Activity In Vitro. Alcohol. Clin. Exp. Res. 2014 Mar;38(3):683-93
  Liu L et al
  2014/01/01
  
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• 参照：
  

• No.： 48
• 文献情報：
  Lim SK et al. The ER stress-mediated decrease in DDAH1 expression is involved in formaldehyde-induced apoptosis in lung epithelial cells. Food Chem. Toxicol. 2013 Dec;62:763-9
  Lim SK et al
  2013/01/01
  
• 備考：
  
• 参照：
  

• No.： 49
• 文献情報：
  Kemp KL et al. The serine-threonine kinase inositol-requiring enzyme 1α (IRE1α) promotes IL-4 production in T helper cells. J. Biol. Chem. 2013 Nov;288(46):33272-82
  Kemp KL et al
  2013/01/01
  
• 備考：
  
• 参照：
  

• No.： 50
• 文献情報：
  Jung DY et al. KLF15 is a molecular link between endoplasmic reticulum stress and insulin resistance. PLoS ONE 2013;8(10):e77851
  Jung DY et al
  2013/01/01
  
• 備考：
  
• 参照：
  

• No.： 51
• 文献情報：
  Ishimura S et al. Reduction of endoplasmic reticulum stress inhibits neointima formation after vascular injury. Sci Rep 2014;4:6943
  Ishimura S et al
  2014/01/01
  
• 備考：
  Species: Mouse, Applications: WB, IHC-P
• 参照：
  

• No.： 52
• 文献情報：
  Negroni A et al. Endoplasmic reticulum stress and unfolded protein response are involved in paediatric inflammatory bowel disease. Dig Liver Dis 2014 Sep;46(9):788-94
  Negroni A et al
  2014/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 53
• 文献情報：
  K旦hler C et al. Granulovacuolar degeneration and unfolded protein response in mouse models of tauopathy and Aβ amyloidosis. Neurobiol. Dis. 2014 Nov;71:169-79
  K旦hler C et al
  2014/01/01
  
• 備考：
  Species: Mouse, Applications: IHC-P
• 参照：
  

• No.： 54
• 文献情報：
  Wu Y et al. Deficiency of osteoblastic Arl6ip5 impaired osteoblast differentiation and enhanced osteoclastogenesis via disturbance of ER calcium homeostasis and induction of ER stress-mediated apoptosis. Cell Death Dis 2014;5:e1464
  Wu Y et al
  2014/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 55
• 文献情報：
  Liew CW et al. Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic β cells. Proc. Natl. Acad. Sci. U.S.A. 2014 Jun;111(22):E2319-28
  Liew CW et al
  2014/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 56
• 文献情報：
  Suh HN et al. Glucosamine-induced Sp1 O-GlcNAcylation ameliorates hypoxia-induced SGLT dysfunction in primary cultured renal proximal tubule cells. J. Cell. Physiol. 2014 Oct;229(10):1557-68
  Suh HN et al
  2014/01/01
  
• 備考：
  Species: Rabbit, Applications: WB
• 参照：
  

• No.： 57
• 文献情報：
  Kurahashi T et al. Reductive detoxification of acrolein as a potential role for aldehyde reductase (AKR1A) in mammals. Biochem. Biophys. Res. Commun. 2014 Sep;452(1):136-41
  Kurahashi T et al
  2014/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 58
• 文献情報：
  Park KS et al. Transcription elongation factor ELL2 drives Ig secretory-specific mRNA production and the unfolded protein response. J. Immunol. 2014 Nov;193(9):4663-74
  Park KS et al
  2014/01/01
  
• 備考：
  
• 参照：
  

• No.： 59
• 文献情報：
  Cai XH et al. Endoplasmic reticulum stress plays critical role in brain damage after chronic intermittent hypoxia in growing rats. Exp. Neurol. 2014 Jul;257:148-56
  Cai XH et al
  2014/01/01
  
• 備考：
  Species: Rat, Applications: WB
• 参照：
  

• No.： 60
• 文献情報：
  Bonnet Wersinger D et al. Impairment of visual function and retinal ER stress activation in Wfs1-deficient mice. PLoS ONE 2014;9(5):e97222
  Bonnet Wersinger D et al
  2014/01/01
  
• 備考：
  Species: Mouse, Applications: IHC-Fr
• 参照：
  

• No.： 61
• 文献情報：
  Yang Y et al. Endoplasmic Reticulum Stress-Mediated Apoptotic Pathway Is Involved in Corpus Luteum Regression in Rats. Reprod Sci 2014 Oct;
  Yang Y et al
  2014/01/01
  
• 備考：
  Species: Mouse, Applications: IHC-P
• 参照：
  

• No.： 62
• 文献情報：
  Zhu X et al. Ubiquitination of inositol-requiring enzyme 1 (IRE1) by the E3 ligase CHIP mediates the IRE1/TRAF2/JNK pathway. J. Biol. Chem. 2014 Oct;289(44):30567-77
  Zhu X et al
  2014/01/01
  
• 備考：
  
• 参照：
  

• No.： 63
• 文献情報：
  Hosoi T et al. TERT attenuated ER stress-induced cell death. Biochem. Biophys. Res. Commun. 2014 May;447(2):378-82
  Hosoi T et al
  2014/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 64
• 文献情報：
  Walter F et al. Imaging of single cell responses to ER stress indicates that the relative dynamics of IRE1/XBP1 and PERK/ATF4 signalling rather than a switch between signalling branches determine cell survival. Cell Death Differ. 2015 Jan;
  Walter F et al
  2015/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 65
• 文献情報：
  Iwasaki N et al. An ATF4-Signal-Modulating Machine Other Than GADD34 Acts in ATF4-to-CHOP Signaling to Block CHOP Expression in ER-Stress-Related Autophagy. J. Cell. Biochem. 2015 Jul;116(7):1300-9
  Iwasaki N et al
  2015/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 66
• 文献情報：
  Jeon YJ et al. Regulation of glutamine carrier proteins by RNF5 determines breast cancer response to ER stress-inducing chemotherapies. Cancer Cell 2015 Mar;27(3):354-69
  Jeon YJ et al
  2015/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 67
• 文献情報：
  Shao M et al. Hepatic IRE1α regulates fasting-induced metabolic adaptive programs through the XBP1s-PPARα axis signalling. Nat Commun 2014;5:3528
  Shao M et al
  2014/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 68
• 文献情報：
  Narsale AA et al. Liver inflammation and metabolic signaling in ApcMin/+ mice: the role of cachexia progression. PLoS ONE 2015;10(3):e0119888
  Narsale AA et al
  2015/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 69
• 文献情報：
  Kosakowska-Cholody T et al. HKH40A downregulates GRP78/BiP expression in cancer cells. Cell Death Dis 2014;5:e1240
  Kosakowska-Cholody T et al
  2014/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 70
• 文献情報：
  Quan X et al. Melatonin inhibits tunicamycin-induced endoplasmic reticulum stress and insulin resistance in skeletal muscle cells. Biochem. Biophys. Res. Commun. 2015 Aug;463(4):1102-7
  Quan X et al
  2015/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 71
• 文献情報：
  Jahng JW et al. Pressure Overload-Induced Cardiac Dysfunction in Aged Male Adiponectin Knockout Mice Is Associated With Autophagy Deficiency. Endocrinology 2015 Jul;156(7):2667-77
  Jahng JW et al
  2015/01/01
  
• 備考：
  Species: Mouse
• 参照：
  

• No.： 72
• 文献情報：
  Shen Y et al. The switch from ER stress-induced apoptosis to autophagy via ROS-mediated JNK/p62 signals: A survival mechanism in methotrexate-resistant choriocarcinoma cells. Exp. Cell Res. 2015 Jun;334(2):207-18
  Shen Y et al
  2015/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 73
• 文献情報：
  Winnay JN et al. A regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box-binding protein-1 to modulate the unfolded protein response. Nat. Med. 2010 Apr;16(4):438-45
  Winnay JN et al
  2010/01/01
  
• 備考：
  Species: Mouse
• 参照：
  

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