Anti-HIF Prolyl Hydroxylase 3, Rabbit-Poly <Anti-PHD3> <Anti-EGLN3>

データシート

• 商品コード：NB100-139
• メーカー：NOV
• 包装：0.1ml
• 価格： ¥91,000
• 在庫：無(未発注)

マイリストに追加 マイリストに追加済

• No.： 1
• 文献情報：
  Asikainen TM et al. Activation of hypoxia-inducible factors in hyperoxia through prolyl 4-hydroxylase blockade in cells and explants of primate lung. Proc. Natl. Acad. Sci. U.S.A. 2005 Jul;102(29):10212-7
  Asikainen TM et al
  2005/01/01
  
• 備考：
  Western blot, human
• 参照：
  

• No.： 2
• 文献情報：
  Jokilehto T et al. Overexpression and nuclear translocation of hypoxia-inducible factor prolyl hydroxylase PHD2 in head and neck squamous cell carcinoma is associated with tumor aggressiveness. Clin. Cancer Res. 2006 Feb;12(4):1080-7
  Jokilehto T et al
  2006/01/01
  
• 備考：
  
• 参照：
  

• No.： 3
• 文献情報：
  Asikainen TM et al. Enhancement of angiogenic effectors through hypoxia-inducible factor in preterm primate lung in vivo. Am. J. Physiol. Lung Cell Mol. Physiol. 2006 Oct;291(4):L588-95
  Asikainen TM et al
  2006/01/01
  
• 備考：
  
• 参照：
  

• No.： 4
• 文献情報：
  Li N et al. Expression and actions of HIF prolyl-4-hydroxylase in the rat kidneys. Am. J. Physiol. Renal Physiol. 2007 Jan;292(1):F207-16
  Li N et al
  2007/01/01
  
• 備考：
  
• 参照：
  

• No.： 5
• 文献情報：
  Anderson K et al. Regulation of cellular levels of Sprouty2 protein by prolyl hydroxylase domain and von Hippel-Lindau proteins. J. Biol. Chem. 2011 Dec;286(49):42027-36
  Anderson K et al
  2011/01/01
  
• 備考：
  
• 参照：
  

• No.： 6
• 文献情報：
  Place TL et al. Aberrant promoter CpG methylation is a mechanism for impaired PHD3 expression in a diverse set of malignant cells. PLoS ONE 2011;6(1):e14617
  Place TL et al
  2011/01/01
  
• 備考：
  
• 参照：
  

• No.： 7
• 文献情報：
  H旦gel H et al. Prolyl hydroxylase PHD3 enhances the hypoxic survival and G1 to S transition of carcinoma cells. PLoS ONE 2011;6(11):e27112
  H旦gel H et al
  2011/01/01
  
• 備考：
  
• 参照：
  

• No.： 8
• 文献情報：
  Xie L et al. Oxygen-regulated beta(2)-adrenergic receptor hydroxylation by EGLN3 and ubiquitylation by pVHL. Sci Signal 2009;2(78):ra33
  Xie L et al
  2009/01/01
  
• 備考：
  
• 参照：
  

• No.： 9
• 文献情報：
  Luo W et al. Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1. Cell 2011 May;145(5):732-44
  Luo W et al
  2011/01/01
  
• 備考：
  
• 参照：
  

• No.： 10
• 文献情報：
  Fu J et al. EGLN3 prolyl hydroxylase regulates skeletal muscle differentiation and myogenin protein stability. J. Biol. Chem. 2007 Apr;282(17):12410-8
  Fu J et al
  2007/01/01
  
• 備考：
  
• 参照：
  

• No.： 11
• 文献情報：
  Rantanen K et al. Prolyl hydroxylase PHD3 activates oxygen-dependent protein aggregation. Mol. Biol. Cell 2008 May;19(5):2231-40
  Rantanen K et al
  2008/01/01
  
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• 参照：
  

• No.： 12
• 文献情報：
  Ginouv竪s A et al. PHDs overactivation during chronic hypoxia &quot;desensitizes&quot; HIFalpha and protects cells from necrosis. Proc. Natl. Acad. Sci. U.S.A. 2008 Mar;105(12):4745-50
  Ginouv竪s A et al
  2008/01/01
  
• 備考：
  
• 参照：
  

• No.： 13
• 文献情報：
  Wong W et al. mAKAP compartmentalizes oxygen-dependent control of HIF-1alpha. Sci Signal 2008;1(51):ra18
  Wong W et al
  2008/01/01
  
• 備考：
  
• 参照：
  

• No.： 14
• 文献情報：
  Luukkaa M et al. Expression of the cellular oxygen sensor PHD2 (EGLN-1) predicts radiation sensitivity in squamous cell cancer of the head and neck. Int. J. Radiat. Biol. 2009;85(10):900-8
  Luukkaa M et al
  2009/01/01
  
• 備考：
  
• 参照：
  

• No.： 15
• 文献情報：
  Fujita N et al. Expression of prolyl hydroxylases (PHDs) is selectively controlled by HIF-1 and HIF-2 proteins in nucleus pulposus cells of the intervertebral disc: distinct roles of PHD2 and PHD3 proteins in controlling HIF-1&#x3B1; activity in hypoxia.
  Fujita N et al
  2012/01/01
  
• 備考：
  Applications: ICC, IF, WB, Species: Human, Rat
• 参照：
  

• No.： 16
• 文献情報：
  Khan Z et al. Peroxisomal localization of hypoxia-inducible factors and hypoxia-inducible factor regulatory hydroxylases in primary rat hepatocytes exposed to hypoxia-reoxygenation. Am. J. Pathol. 2006 Oct;169(4):1251-69
  Khan Z et al
  2006/01/01
  
• 備考：
  Species: Rat, Applications: WB, IHC-P, ICC/IF, EM
• 参照：
  

• No.： 17
• 文献情報：
  Taniguchi CM et al. Cross-talk between hypoxia and insulin signaling through Phd3 regulates hepatic glucose and lipid metabolism and ameliorates diabetes. Nat. Med. 2013 Oct;19(10):1325-30
  Taniguchi CM et al
  2013/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 18
• 文献情報：
  Gal叩n-Cobo A et al. Cellular overexpression of aquaporins slows down the natural HIF-2&#x3B1; degradation during prolonged hypoxia. Gene 2013 Jun;522(1):18-26
  Gal叩n-Cobo A et al
  2013/01/01
  
• 備考：
  Species: Rat, Applications: WB
• 参照：
  

• No.： 19
• 文献情報：
  Cervera AM et al. An alternatively spliced transcript of the PHD3 gene retains prolyl hydroxylase activity. Cancer Lett. 2006 Feb;233(1):131-8
  Cervera AM et al
  2006/01/01
  
• 備考：
  
• 参照：
  

• No.： 20
• 文献情報：
  Rawluszko AA et al. Expression and DNA methylation levels of prolyl hydroxylases PHD1, PHD2, PHD3 and asparaginyl hydroxylase FIH in colorectal cancer. BMC Cancer 2013;13:526
  Rawluszko AA et al
  2013/01/01
  
• 備考：
  
• 参照：
  

• No.： 21
• 文献情報：
  Place TL et al. Prolyl-4-Hydroxylase 3 (PHD3) Expression Is Downregulated during Epithelial-to-Mesenchymal Transition. PLoS ONE 2013;8(12):e83021
  Place TL et al
  2013/01/01
  
• 備考：
  
• 参照：
  

• No.： 22
• 文献情報：
  Vogler M et al. Pre- and post-conditional inhibition of prolyl-4-hydroxylase domain enzymes protects the heart from an ischemic insult. Pflugers Arch. 2015 Jan;
  Vogler M et al
  2015/01/01
  
• 備考：
  Species: Mouse, Applications: IHC-P
• 参照：
  

• No.： 23
• 文献情報：
  Li J et al. Prolyl-4-hydroxylase Domain Protein 2 Controls NF-&#x3BA;B/p65 Transactivation and Enhances the Catabolic Effects of Inflammatory Cytokines on Cells of the Nucleus Pulposus. J. Biol. Chem. 2015 Mar;290(11):7195-207
  Li J et al
  2015/01/01
  
• 備考：
  Species: Rat, Human, Applications: WB
• 参照：
  

• No.： 24
• 文献情報：
  H旦gel H et al. Hypoxia inducible prolyl hydroxylase PHD3 maintains carcinoma cell growth by decreasing the stability of p27. Mol. Cancer 2015;14:143
  H旦gel H et al
  2015/01/01
  
• 備考：
  Species: Human, Applications: WB, ICC/IF
• 参照：
  

• No.： 25
• 文献情報：
  Adam MG et al. SIAH ubiquitin ligases regulate breast cancer cell migration and invasion independent of the oxygen status. Cell Cycle 2015;14(23):3734-47
  Adam MG et al
  2015/01/01
  
• 備考：
  
• 参照：
  

• No.： 26
• 文献情報：
  Sch旦del J et al. HIF-prolyl hydroxylases in the rat kidney: physiologic expression patterns and regulation in acute kidney injury. Am. J. Pathol. 2009 May;174(5):1663-74
  Sch旦del J et al
  2009/01/01
  
• 備考：
  
• 参照：
  

• No.： 27
• 文献情報：
  Chan DA et al. Tumor vasculature is regulated by PHD2-mediated angiogenesis and bone marrow-derived cell recruitment. Cancer Cell 2009 Jun;15(6):527-38
  Chan DA et al
  2009/01/01
  
• 備考：
  
• 参照：
  

• No.： 28
• 文献情報：
  Lomb DJ et al. Prolyl hydroxylase inhibitors delay neuronal cell death caused by trophic factor deprivation. J. Neurochem. 2007 Dec;103(5):1897-906
  Lomb DJ et al
  2007/01/01
  
• 備考：
  
• 参照：
  

• No.： 29
• 文献情報：
  Dalgard CL et al. Endogenous 2-oxoacids differentially regulate expression of oxygen sensors. Biochem. J. 2004 Jun;380(Pt 2):419-24
  Dalgard CL et al
  2004/01/01
  
• 備考：
  
• 参照：
  

• No.： 30
• 文献情報：
  Di Fonzo MM et al. The population growth consequences of variation in individual heterozygosity. PLoS ONE 2011;6(5):e19667
  Di Fonzo MM et al
  2011/01/01
  
• 備考：
  
• 参照：
  

• No.： 31
• 文献情報：
  Newpher TM et al. Glutamate receptor dynamics in dendritic microdomains. Neuron 2008 May;58(4):472-97
  Newpher TM et al
  2008/01/01
  
• 備考：
  
• 参照：
  

• No.： 32
• 文献情報：
  Pan H et al. RNA binding protein HuR regulates extracellular matrix gene expression and pH homeostasis independent of controlling HIF-1&#x3B1; signaling in nucleus pulposus cells. Matrix Biol. 2018 Aug;
  Pan H et al
  2018/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 33
• 文献情報：
  Barnes EA et al. Loss of smooth muscle cell hypoxia inducible factor-1&#x3B1; underlies increased vascular contractility in pulmonary hypertension. FASEB J. 2017 Feb;31(2):650-662
  Barnes EA et al
  2017/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 34
• 文献情報：
  Miikkulainen P et al. HIF prolyl hydroxylase PHD3 regulates translational machinery and glucose metabolism in clear cell renal cell carcinoma. Cancer Metab 2017;5:5
  Miikkulainen P et al
  2017/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 35
• 文献情報：
  Iriondo O et al. Distinct breast cancer stem/progenitor cell populations require either HIF1&#x3B1; or loss of PHD3 to expand under hypoxic conditions. Oncotarget 2015 Oct;6(31):31721-39
  Iriondo O et al
  2015/01/01
  
• 備考：
  WB
• 参照：
  

• No.： 36
• 文献情報：
  Bruno T et al. Che-1 sustains hypoxic response of colorectal cancer cells by affecting Hif-1&#x3B1; stabilization. J. Exp. Clin. Cancer Res. 2017 02;36(1):32
  Bruno T et al
  2017/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 37
• 文献情報：
  Bryant JD et al. Regulation of Hypoxia-Inducible Factor 1&#x3B1; during Hypoxia by DAP5-Induced Translation of PHD2. Mol. Cell. Biol. 2018 Jun;38(11)
  Bryant JD et al
  2018/01/01
  
• 備考：
  WB
• 参照：
  

• No.： 38
• 文献情報：
  Oh ET et al. NQO1 inhibits proteasome-mediated degradation of HIF-1&#x3B1;. Nat Commun 2016 Dec;7:13593
  Oh ET et al
  2016/01/01
  
• 備考：
  Species: Mouse, Applications:
• 参照：
  

• No.： 39
• 文献情報：
  Kozlova N et al. The Pro-Oncogenic Adaptor CIN85 Acts as an Inhibitory Binding Partner of Hypoxia-Inducible Factor Prolyl Hydroxylase 2. Cancer Res 2019 08;79(16):4042-4056
  Kozlova N et al
  2019/01/01
  
• 備考：
  
• 参照：
  

• No.： 40
• 文献情報：
  Shi M et al. APC^CDC20-mediated degradation of PHD3 stabilizes HIF-1a and promotes tumorigenesis in hepatocellular carcinoma. Cancer Lett 2021 01;496:144-155
  Shi M et al
  2021/01/01
  
• 備考：
  
• 参照：
  

• No.： 41
• 文献情報：
  Ju S et al. LRP5 Regulates HIF-1&#x3B1; Stability via Interaction with PHD2 in Ischemic Myocardium. Int J Mol Sci 2021 Jun;22(12)
  Ju S et al
  2021/01/01
  
• 備考：
  
• 参照：
  

• No.： 42
• 文献情報：
  Ciminera AK et al. Elevated glucose increases genomic instability by inhibiting nucleotide excision repair. Life Sci Alliance 2021 10;4(10)
  Ciminera AK et al
  2021/01/01
  
• 備考：
  Species: Human, Applications: MS
• 参照：
  

• No.： 43
• 文献情報：
  Nasteska D et al. Prolyl-4-hydroxylase 3 maintains &#x3B2; cell glucose metabolism during fatty acid excess in mice. JCI Insight 2021 Aug;6(16)
  Nasteska D et al
  2021/01/01
  
• 備考：
  Applications: IHC-P
• 参照：