Anti-HIF-1α, Rabbit-Poly <Anti-Hypoxia-Inducible Factor 1α>

データシート

• 商品コード：NB100-134
• メーカー：NOV
• 包装：100μl
• 価格： ¥103,000
• 在庫：無(未発注)

マイリストに追加 マイリストに追加済

• No.： 1
• 文献情報：
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• 備考：
  Western blot, rat
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• No.： 2
• 文献情報：
  Liu X et al. Hypoxic preconditioning of cardiomyocytes and cardioprotection: phophorylation of HIF-1alpha induced by p42/p44 mitogen-activated protein kinases is involved. Pathophysiology 2003 Sep;9(4):201-205
  Liu X et al
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• No.： 3
• 文献情報：
  Ietta F et al. Dynamic HIF1A regulation during human placental development. Biol. Reprod. 2006 Jul;75(1):112-21
  Ietta F et al
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• No.： 4
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  Harris JR et al
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• No.： 5
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  Wang J et al. Cytoprotective effects of hypoxia against cisplatin-induced tubular cell apoptosis: involvement of mitochondrial inhibition and p53 suppression. J. Am. Soc. Nephrol. 2006 Jul;17(7):1875-85
  Wang J et al
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• No.： 6
• 文献情報：
  Litz J et al. Imatinib inhibits c-Kit-induced hypoxia-inducible factor-1alpha activity and vascular endothelial growth factor expression in small cell lung cancer cells. Mol. Cancer Ther. 2006 Jun;5(6):1415-22
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• No.： 7
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  Lin Q et al. Differentiation arrest by hypoxia. J. Biol. Chem. 2006 Oct;281(41):30678-83
  Lin Q et al
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• 参照：
  

• No.： 8
• 文献情報：
  Liao D et al. Hypoxia-inducible factor-1alpha is a key regulator of metastasis in a transgenic model of cancer initiation and progression. Cancer Res. 2007 Jan;67(2):563-72
  Liao D et al
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• No.： 9
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  Harvey AJ et al. Regulation of gene expression in bovine blastocysts in response to oxygen and the iron chelator desferrioxamine. Biol. Reprod. 2007 Jul;77(1):93-101
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• No.： 10
• 文献情報：
  Kim JW et al. Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1. Mol. Cell. Biol. 2007 Nov;27(21):7381-93
  Kim JW et al
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• 参照：
  

• No.： 11
• 文献情報：
  Sikder D et al. The neurohormone orexin stimulates hypoxia-inducible factor-1 activity. Genes Dev. 2007 Nov;21(22):2995-3005
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• No.： 12
• 文献情報：
  Nikinmaa M et al. Population origin, development and temperature of development affect the amounts of HSP70, HSP90 and the putative hypoxia-inducible factor in the tadpoles of the common frog Rana temporaria. J. Exp. Biol. 2008 Jun;211(Pt 12):1999-2004
  Nikinmaa M et al
  2008/01/01
  
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• 参照：
  

• No.： 13
• 文献情報：
  Lauzier MC et al. (2R)-[(4-Biphenylylsulfonyl)amino]-N-hydroxy-3-phenylpropionamide (BiPS), a matrix metalloprotease inhibitor, is a novel and potent activator of hypoxia-inducible factors. Mol. Pharmacol. 2008 Jul;74(1):282-8
  Lauzier MC et al
  2008/01/01
  
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• 参照：
  

• No.： 14
• 文献情報：
  Meyuhas R et al. A Key role for cyclic AMP-responsive element binding protein in hypoxia-mediated activation of the angiogenesis factor CCN1 (CYR61) in Tumor cells. Mol. Cancer Res. 2008 Sep;6(9):1397-409
  Meyuhas R et al
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• 参照：
  

• No.： 15
• 文献情報：
  Copple BL et al. Hypoxia-inducible factor activation in myeloid cells contributes to the development of liver fibrosis in cholestatic mice. J. Pharmacol. Exp. Ther. 2012 May;341(2):307-16
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• 参照：
  

• No.： 16
• 文献情報：
  Rane S et al. Downregulation of miR-199a derepresses hypoxia-inducible factor-1alpha and Sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytes. Circ. Res. 2009 Apr;104(7):879-86
  Rane S et al
  2009/01/01
  
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• 参照：
  

• No.： 17
• 文献情報：
  Frede S et al. Hypoxia-inducible factor (HIF) 1alpha accumulation and HIF target gene expression are impaired after induction of endotoxin tolerance. J. Immunol. 2009 May;182(10):6470-6
  Frede S et al
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• 参照：
  

• No.： 18
• 文献情報：
  Piantadosi CA et al. Transcriptional Regulation of SDHa flavoprotein by nuclear respiratory factor-1 prevents pseudo-hypoxia in aerobic cardiac cells. J. Biol. Chem. 2008 Apr;283(16):10967-77
  Piantadosi CA et al
  2008/01/01
  
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• 参照：
  

• No.： 19
• 文献情報：
  Rennie MY et al. Expansion of the fetoplacental vasculature in late gestation is strain dependent in mice. Am. J. Physiol. Heart Circ. Physiol. 2012 Mar;302(6):H1261-73
  Rennie MY et al
  2012/01/01
  
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• 参照：
  

• No.： 20
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  Young HW et al. Central role of Muc5ac expression in mucous metaplasia and its regulation by conserved 5&quot; elements. Am. J. Respir. Cell Mol. Biol. 2007 Sep;37(3):273-90
  Young HW et al
  2007/01/01
  
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• 参照：
  

• No.： 21
• 文献情報：
  Ravichandran K et al. Interleukin-1beta-induced iNOS expression in human lung carcinoma A549 cells: involvement of STAT and MAPK pathways. Indian J. Exp. Biol. 2011 Nov;49(11):840-7
  Ravichandran K et al
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• 参照：
  

• No.： 22
• 文献情報：
  Trollmann R et al. Placental HIFs as markers of cerebral hypoxic distress in fetal mice. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2008 Dec;295(6):R1973-81
  Trollmann R et al
  2008/01/01
  
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• 参照：
  

• No.： 23
• 文献情報：
  Botusan IR et al. Stabilization of HIF-1alpha is critical to improve wound healing in diabetic mice. Proc. Natl. Acad. Sci. U.S.A. 2008 Dec;105(49):19426-31
  Botusan IR et al
  2008/01/01
  
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• 参照：
  

• No.： 24
• 文献情報：
  Ohtomo S et al. Cobalt ameliorates renal injury in an obese, hypertensive type 2 diabetes rat model. Nephrol. Dial. Transplant. 2008 Apr;23(4):1166-72
  Ohtomo S et al
  2008/01/01
  
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• 参照：
  

• No.： 25
• 文献情報：
  Naito Y et al. Adaptive response of the heart to long-term anemia induced by iron deficiency. Am. J. Physiol. Heart Circ. Physiol. 2009 Mar;296(3):H585-93
  Naito Y et al
  2009/01/01
  
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• 参照：
  

• No.： 26
• 文献情報：
  Zhang H et al. Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia. J. Biol. Chem. 2008 Apr;283(16):10892-903
  Zhang H et al
  2008/01/01
  
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• 参照：
  

• No.： 27
• 文献情報：
  Edrey YH et al. Sustained high levels of neuregulin-1 in the longest-lived rodents; a key determinant of rodent longevity. Aging Cell 2012 Apr;11(2):213-22
  Edrey YH et al
  2012/01/01
  
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• 参照：
  

• No.： 28
• 文献情報：
  Xia X et al. Preferential binding of HIF-1 to transcriptionally active loci determines cell-type specific response to hypoxia. Genome Biol. 2009;10(10):R113
  Xia X et al
  2009/01/01
  
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• 参照：
  

• No.： 29
• 文献情報：
  Singh RP et al. Silibinin inhibits colorectal cancer growth by inhibiting tumor cell proliferation and angiogenesis. Cancer Res. 2008 Mar;68(6):2043-50
  Singh RP et al
  2008/01/01
  
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• 参照：
  

• No.： 30
• 文献情報：
  Belibi F et al. Hypoxia-inducible factor-1&#x3B1; (HIF-1&#x3B1;) and autophagy in polycystic kidney disease (PKD). Am. J. Physiol. Renal Physiol. 2011 May;300(5):F1235-43
  Belibi F et al
  2011/01/01
  
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• 参照：
  

• No.： 31
• 文献情報：
  Westfall SD et al. Identification of oxygen-sensitive transcriptional programs in human embryonic stem cells. Stem Cells Dev. 2008 Oct;17(5):869-81
  Westfall SD et al
  2008/01/01
  
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• 参照：
  

• No.： 32
• 文献情報：
  Bansal A et al. Choline phosphorylation and regulation of transcription of choline kinase &#x3B1; in hypoxia. J. Lipid Res. 2012 Jan;53(1):149-57
  Bansal A et al
  2012/01/01
  
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• 参照：
  

• No.： 33
• 文献情報：
  Filby CE et al. Partial pulmonary embolization disrupts alveolarization in fetal sheep. Respir. Res. 2010;11:42
  Filby CE et al
  2010/01/01
  
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• No.： 34
• 文献情報：
  Land SC et al. Redox regulation of lung development and perinatal lung epithelial function. Antioxid. Redox Signal. ;7(1-2):92-107
  Land SC et al
  
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• No.： 35
• 文献情報：
  Wang Y et al. MicroRNA-138 modulates DNA damage response by repressing histone H2AX expression. Mol. Cancer Res. 2011 Aug;9(8):1100-11
  Wang Y et al
  2011/01/01
  
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• 参照：
  

• No.： 36
• 文献情報：
  Raina S et al. Anti-VEGF antibody treatment accelerates polycystic kidney disease. Am. J. Physiol. Renal Physiol. 2011 Oct;301(4):F773-83
  Raina S et al
  2011/01/01
  
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• 参照：
  

• No.： 37
• 文献情報：
  Tuomela J et al. Low TLR9 expression defines an aggressive subtype of triple-negative breast cancer. Breast Cancer Res. Treat. 2012 Sep;135(2):481-93
  Tuomela J et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: WB, IHC
• 参照：
  

• No.： 38
• 文献情報：
  Morote-Garcia JC et al. Endothelial Semaphorin 7A promotes neutrophil migration during hypoxia. Proc. Natl. Acad. Sci. U.S.A. 2012 Aug;109(35):14146-51
  Morote-Garcia JC et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ChIP
• 参照：
  

• No.： 39
• 文献情報：
  Anderson S et al. 2-Hydroxyestradiol slows progression of experimental polycystic kidney disease. Am. J. Physiol. Renal Physiol. 2012 Mar;302(5):F636-45
  Anderson S et al
  2012/01/01
  
• 備考：
  Species: Rat, Applications: WB
• 参照：
  

• No.： 40
• 文献情報：
  Rennie MY. Development of the Fetoplacental Vascular Tree in Mice During Normal and Growth Restricted Pregnancies. 2011 University of Toronto. 2011.
  
  
• 備考：
  
• 参照：
  

• No.： 41
• 文献情報：
  Clambey ET et al. Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa. Proc. Natl. Acad. Sci. U.S.A. 2012 Oct;109(41):E2784-93
  Clambey ET et al
  2012/01/01
  
• 備考：
  Applications: ChIP
• 参照：
  

• No.： 42
• 文献情報：
  Hernandez-Luna MA et al. Hypoxia inducible factor-1&#x3B1; induces chemoresistance phenotype in non-Hodgkin lymphoma cell line via up-regulation of Bcl-(xL). Leuk. Lymphoma 2012 Oct;
  Hernandez-Luna MA et al
  2012/01/01
  
• 備考：
  Applications: IHC, WB
• 参照：
  

• No.： 43
• 文献情報：
  Aguado-Fraile E et al. miR-127 protects proximal tubule cells against ischemia/reperfusion: identification of kinesin family member 3B as miR-127 target. PLoS ONE 2012;7(9):e44305
  Aguado-Fraile E et al
  2012/01/01
  
• 備考：
  Applications: ChIP
• 参照：
  

• No.： 44
• 文献情報：
  Pawlus MR et al. Upstream Stimulatory Factor 2 and Hypoxia-Inducible Factor 2&#x3B1; (HIF2&#x3B1;) Cooperatively Activate HIF2 Target Genes during Hypoxia. Mol. Cell. Biol. 2012 Nov;32(22):4595-610
  Pawlus MR et al
  2012/01/01
  
• 備考：
  Applications: ChIP
• 参照：
  

• No.： 45
• 文献情報：
  Yao W et al. Effects of dietary ratio of n-6 to n-3 polyunsaturated fatty acids on immunoglobulins, cytokines, fatty acid composition, and performance of lactating sows and suckling piglets. J Anim Sci Biotechnol 2012;3(1):43
  Yao W et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: IHC
• 参照：
  

• No.： 46
• 文献情報：
  Enzmann G et al. The neurovascular unit as a selective barrier to polymorphonuclear granulocyte (PMN) infiltration into the brain after ischemic injury. Acta Neuropathol. 2013 Mar;125(3):395-412
  Enzmann G et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: IHC
• 参照：
  

• No.： 47
• 文献情報：
  Chiang CK et al. Endoplasmic reticulum stress signal impairs erythropoietin production: a role for ATF4. Am. J. Physiol., Cell Physiol. 2013 Feb;304(4):C342-53
  Chiang CK et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: WB, ChIP
• 参照：
  

• No.： 48
• 文献情報：
  Dikow R et al. Uremia aggravates left ventricular remodeling after myocardial infarction. Am. J. Nephrol. 2010;32(1):13-22
  Dikow R et al
  2010/01/01
  
• 備考：
  Species: Rat, Applications: IHC-P
• 参照：
  

• No.： 49
• 文献情報：
  Eftedal I et al. Early genetic responses in rat vascular tissue after simulated diving. Physiol. Genomics 2012 Dec;44(24):1201-7
  Eftedal I et al
  2012/01/01
  
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• 参照：
  

• No.： 50
• 文献情報：
  Gubin MM et al. Overexpression of the RNA binding protein HuR impairs tumor growth in triple negative breast cancer associated with deficient angiogenesis. Cell Cycle 2010 Aug;9(16):3337-46
  Gubin MM et al
  2010/01/01
  
• 備考：
  Species: Mouse, Applications: IHC
• 参照：
  

• No.： 51
• 文献情報：
  Kelly CJ et al. Fundamental role for HIF-1&#x3B1; in constitutive expression of human &#x3B2; defensin-1. Mucosal Immunol 2013 Mar;
  Kelly CJ et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: ChIP
• 参照：
  

• No.： 52
• 文献情報：
  Ganapathy S et al. Low-dose arsenic induces chemotherapy protection via p53/NF-&#x3BA;B-mediated metabolic regulation. Oncogene 2013 Mar;
  Ganapathy S et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: ICC/IF
• 参照：
  

• No.： 53
• 文献情報：
  Shoji K et al. Sperm-associated antigen 4, a novel hypoxia-inducible factor 1 target, regulates cytokinesis, and its expression correlates with the prognosis of renal cell carcinoma. Am. J. Pathol. 2013 Jun;182(6):2191-203
  Shoji K et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: ChIP
• 参照：
  

• No.： 54
• 文献情報：
  Chu X et al. Multiple Microvascular Alterations in Pancreatic Islets and Neuroendocrine Tumors of a Men1 Mouse Model. Am. J. Pathol. 2013 Apr;
  Chu X et al
  2013/01/01
  
• 備考：
  Species: Mouse, Applications: IHC-P
• 参照：
  

• No.： 55
• 文献情報：
  Pawlus MR et al. STAT3 and HIF1&#x3B1; cooperatively activate HIF1 target genes in MDA-MB-231 and RCC4 cells. Oncogene 2013 Apr;
  Pawlus MR et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: ChIP
• 参照：
  

• No.： 56
• 文献情報：
  Bett JS et al. The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability. Biochem. J. 2013 Apr;451(2):185-94
  Bett JS et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 57
• 文献情報：
  Rennie MY. Development of the Fetoplacental Vascular Tree in Mice During Normal and Growth Restricted Pregnancies. 2011 University of Toronto. 2011
  
  
• 備考：
  
• 参照：
  

• No.： 58
• 文献情報：
  Carbajo-Pescador S et al. Inhibition of VEGF expression through blockade of Hif1&#x3B1; and STAT3 signalling mediates the anti-angiogenic effect of melatonin in HepG2 liver cancer cells. Br. J. Cancer 2013 Jul;109(1):83-91
  Carbajo-Pescador S et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: ChIP, ICC/IF
• 参照：
  

• No.： 59
• 文献情報：
  Sena JA et al. BRG1 and BRM Chromatin-Remodeling Complexes Regulate the Hypoxia Response by Acting as Coactivators for a Subset of Hypoxia-Inducible Transcription Factor Target Genes. Mol. Cell. Biol. 2013 Oct;33(19):3849-63
  Sena JA et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 60
• 文献情報：
  Regan Anderson TM et al. Breast tumor kinase (Brk/PTK6) is a mediator of hypoxia-associated breast cancer progression. Cancer Res. 2013 Sep;73(18):5810-20
  Regan Anderson TM et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 61
• 文献情報：
  Kanematsu S et al. Screening for possible miRNA-mRNA associations in a colon cancer cell line. Gene 2014 Jan;533(2):520-31
  Kanematsu S et al
  2014/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 62
• 文献情報：
  Mimura I et al. Dynamic change of chromatin conformation in response to hypoxia enhances the expression of GLUT3 (SLC2A3) by cooperative interaction of hypoxia-inducible factor 1 and KDM3A. Mol. Cell. Biol. 2012 Aug;32(15):3018-32
  Mimura I et al
  2012/01/01
  
• 備考：
  
• 参照：
  

• No.： 63
• 文献情報：
  Glover LE et al. Control of creatine metabolism by HIF is an endogenous mechanism of barrier regulation in colitis. Proc. Natl. Acad. Sci. U.S.A. 2013 Dec;110(49):19820-5
  Glover LE et al
  2013/01/01
  
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• 参照：
  

• No.： 64
• 文献情報：
  Papa Pde C et al. Glucose transporter 1 expression accompanies hypoxia sensing in the cyclic canine corpus luteum. Reproduction 2014 Jan;147(1):81-9
  Papa Pde C et al
  2014/01/01
  
• 備考：
  
• 参照：
  

• No.： 65
• 文献情報：
  Tadokoro H et al. Exosomes derived from hypoxic leukemia cells enhance tube formation in endothelial cells. J. Biol. Chem. 2013 Nov;288(48):34343-51
  Tadokoro H et al
  2013/01/01
  
• 備考：
  
• 参照：
  

• No.： 66
• 文献情報：
  Wang C et al. Local injection of deferoxamine improves neovascularization in ischemic diabetic random flap by increasing HIF-1&#x3B1; and VEGF expression. PLoS ONE 2014;9(6):e100818
  Wang C et al
  2014/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 67
• 文献情報：
  Neary MT et al. Hypoxia signaling controls postnatal changes in cardiac mitochondrial morphology and function. J. Mol. Cell. Cardiol. 2014 Sep;74:340-52
  Neary MT et al
  2014/01/01
  
• 備考：
  Species: Mouse, Applications: ChIP
• 参照：
  

• No.： 68
• 文献情報：
  Prasad P et al. Multifunctional albumin-MnO&#x2082; nanoparticles modulate solid tumor microenvironment by attenuating hypoxia, acidosis, vascular endothelial growth factor and enhance radiation response. ACS Nano 2014 Apr;8(4):3202-12
  Prasad P et al
  2014/01/01
  
• 備考：
  Species: Mouse, Applications: IHC-P
• 参照：
  

• No.： 69
• 文献情報：
  Inoue T et al. Cross-enhancement of ANGPTL4 transcription by HIF1 alpha and PPAR beta/delta is the result of the conformational proximity of two response elements. Genome Biol. 2014;15(4):R63
  Inoue T et al
  2014/01/01
  
• 備考：
  Species: Human, Applications: ChIP
• 参照：
  

• No.： 70
• 文献情報：
  Dong Y et al. Intrauterine ischemic reperfusion switches the fetal transcriptional pattern from HIF-1&#x3B1;- to P53-dependent regulation in the murine brain. PLoS ONE 2014;9(10):e110577
  Dong Y et al
  2014/01/01
  
• 備考：
  Species: Mouse, Applications: WB, ChIP
• 参照：
  

• No.： 71
• 文献情報：
  Robertson ED et al. The oncogenic MicroRNA Hsa-miR-155-5p targets the transcription factor ELK3 and links it to the hypoxia response. PLoS ONE 2014;9(11):e113050
  Robertson ED et al
  2014/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 72
• 文献情報：
  Takeda K et al. Improved vascular survival and growth in the mouse model of hindlimb ischemia by a remote signaling mechanism. Am. J. Pathol. 2014 Mar;184(3):686-96
  Takeda K et al
  2014/01/01
  
• 備考：
  Species: Mouse, Applications: IHC-Fr
• 参照：
  

• No.： 73
• 文献情報：
  Guo X et al. PGC-1&#x3B1; signaling coordinates susceptibility to metabolic and oxidative injury in the inner retina. Am. J. Pathol. 2014 Apr;184(4):1017-29
  Guo X et al
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  Species: Mouse, Applications: ChIP
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  Garc鱈a LN et al. Protective phenotypes of club cells and alveolar macrophages are favored as part of endotoxin-mediated prevention of asthma. Exp. Biol. Med. (Maywood) 2014 Dec;
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  Hung YH et al. Inhibitor of Differentiation-1 and Hypoxia-Inducible Factor-1 Mediate Sonic Hedgehog Induction by Amyloid Beta-Peptide in Rat Cortical Neurons. Mol. Neurobiol. 2014 Dec;
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  Species: Rat, Applications: WB
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  Koh HS et al. The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia. Nat Commun 2015;6:6340
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  Li X et al. KLF5 promotes hypoxia-induced survival and inhibits apoptosis in non-small cell lung cancer cells via HIF-1&#x3B1;. Int. J. Oncol. 2014 Oct;45(4):1507-14
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  Chen X et al. Vascular endothelial growth factor (VEGF) regulation by hypoxia inducible factor-1 alpha (HIF1A) starts and peaks during endometrial breakdown, not repair, in a mouse menstrual-like model. Hum. Reprod. 2015 Sep;30(9):2160-70
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  Pf辰fflin A et al. Increased glucose uptake and metabolism in mesangial cells overexpressing glucose transporter 1 increases interleukin-6 and vascular endothelial growth factor production: role of AP-1 and HIF-1alpha. Cell. Physiol. Biochem. 2006;18(4-5):
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  Forristal CE et al. Pharmacologic stabilization of HIF-1&#x3B1; increases hematopoietic stem cell quiescence in vivo and accelerates blood recovery after severe irradiation. Blood 2013 Jan;121(5):759-69
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  Farrow EG et al. Iron deficiency drives an autosomal dominant hypophosphatemic rickets (ADHR) phenotype in fibroblast growth factor-23 (Fgf23) knock-in mice. Proc. Natl. Acad. Sci. U.S.A. 2011 Nov;108(46):E1146-55
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  Vakili H et al. Negative regulation of human growth hormone gene expression by insulin is dependent on hypoxia-inducible factor binding in primary non-tumor pituitary cells. J. Biol. Chem. 2012 Sep;287(40):33282-92
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  Legendre C et al. Drug-metabolising enzymes are down-regulated by hypoxia in differentiated human hepatoma HepaRG cells: HIF-1alpha involvement in CYP3A4 repression. Eur. J. Cancer 2009 Nov;45(16):2882-92
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