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在庫・価格 : 2024年05月21日 20時03分 現在

商品名 商品コード メーカー 包装 価格 在庫 リスト
Anti-HIF-2α, Mouse-Mono(ep190b) <Anti-Hypoxia-Inducible Factor 2α>
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NB100-132SS NOVノバス バイオロジカルス
Novus biologicals, LLC
25 μl ¥43,000
(未発注)
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在庫・価格 : 2024年05月21日 20時03分 現在

Anti-HIF-2α, Mouse-Mono(ep190b) <Anti-Hypoxia-Inducible Factor 2α>

  • 商品コード:NB100-132SS
  • メーカー:NOV
  • 包装:25μl
  • 価格: ¥43,000
  • 在庫:無(未発注)
使用文献
No. 文献情報 備考 参照
1 Mohan S et al. von Hippel-Lindau protein complex is regulated by cell density. Oncogene 2003 Aug;22(34):5270-80
Mohan S et al
2003/01/01
PubMed
2 Pan Y et al. p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment. Oncogene 2004 Jun;23(29):4975-83
Pan Y et al
2004/01/01
PubMed
3 Tissot van Patot MC et al. Greater vascularity, lowered HIF-1/DNA binding, and elevated GSH as markers of adaptation to in vivo chronic hypoxia. Am. J. Physiol. Lung Cell Mol. Physiol. 2004 Sep;287(3):L525-32
Tissot van Patot MC et al
2004/01/01
PubMed
4 Koike T et al. Hypoxia induces adhesion molecules on cancer cells: A missing link between Warburg effect and induction of selectin-ligand carbohydrates. Proc. Natl. Acad. Sci. U.S.A. 2004 May;101(21):8132-7
Koike T et al
2004/01/01
PubMed
5 Harvey AJ et al. Oxygen-regulated gene expression in bovine blastocysts. Biol. Reprod. 2004 Oct;71(4):1108-19
Harvey AJ et al
2004/01/01
PubMed
6 Mekhail K et al. HIF activation by pH-dependent nucleolar sequestration of VHL. Nat. Cell Biol. 2004 Jul;6(7):642-7
Mekhail K et al
2004/01/01
PubMed
7 Rathmell WK et al. In vitro and in vivo models analyzing von Hippel-Lindau disease-specific mutations. Cancer Res. 2004 Dec;64(23):8595-603
Rathmell WK et al
2004/01/01
PubMed
8 Yoshimura H et al. Prognostic impact of hypoxia-inducible factors 1alpha and 2alpha in colorectal cancer patients: correlation with tumor angiogenesis and cyclooxygenase-2 expression. Clin. Cancer Res. 2004 Dec;10(24):8554-60
Yoshimura H et al
2004/01/01
PubMed
9 Li L et al. Evaluating hypoxia-inducible factor-1alpha as a cancer therapeutic target via inducible RNA interference in vivo. Cancer Res. 2005 Aug;65(16):7249-58
Li L et al
2005/01/01
PubMed
10 Nakamura E et al. Clusterin is a secreted marker for a hypoxia-inducible factor-independent function of the von Hippel-Lindau tumor suppressor protein. Am. J. Pathol. 2006 Feb;168(2):574-84
Nakamura E et al
2006/01/01
PubMed
11 Koizume S et al. Activation of cancer cell migration and invasion by ectopic synthesis of coagulation factor VII. Cancer Res. 2006 Oct;66(19):9453-60
Koizume S et al
2006/01/01
PubMed
12 Yan Q et al. The hypoxia-inducible factor 2alpha N-terminal and C-terminal transactivation domains cooperate to promote renal tumorigenesis in vivo. Mol. Cell. Biol. 2007 Mar;27(6):2092-102
Yan Q et al
2007/01/01
PubMed
13 Bernhardt WM et al. Involvement of hypoxia-inducible transcription factors in polycystic kidney disease. Am. J. Pathol. 2007 Mar;170(3):830-42
Bernhardt WM et al
2007/01/01
PubMed
14 Evans CE et al. Local accumulation of hypoxia-inducible factor 2 alpha during venous thrombus resolution. Thromb. Res. 2014 Sep;134(3):757-60
Evans CE et al
2014/01/01
Species: Mouse, Applications: IHC-P PubMed
15 Lee DW et al. Inhibition of prolyl hydroxylase protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity: model for the potential involvement of the hypoxia-inducible factor pathway in Parkinson disease. J. Biol. Chem. 2009 Oct;2
Lee DW et al
2009/01/01
Applications: PubMed
16 Wiesener MS et al. Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha. Blood 1998 Oct;92(7):2260-8
Wiesener MS et al
1998/01/01
Applications: PubMed
17 Mart鱈n-Puig S et al. Role of iron (II)-2-oxoglutarate-dependent dioxygenases in the generation of hypoxia-induced phosphatidic acid through HIF-1/2 and von Hippel-Lindau-independent mechanisms. J. Biol. Chem. 2004 Mar;279(10):9504-11
Mart鱈n-Puig S et al
2004/01/01
Applications: PubMed
18 Fukui N et al. Development of a novel interferon-&#x3B1;2b gene construct with a repetitive hypoxia-inducible factor binding site and its suppressive effects on human renal cell carcinoma cell lines in vitro. Int. J. Clin. Oncol. 2013 Jun;
Fukui N et al
2013/01/01
Species: Human, Applications: WB PubMed
19 Munksgaard Persson M et al. HIF-2&#x3B1; expression is suppressed in SCLC cells, which survive in moderate and severe hypoxia when HIF-1&#x3B1; is repressed. Am. J. Pathol. 2012 Feb;180(2):494-504
Munksgaard Persson M et al
2012/01/01
Applications: PubMed
20 Noguera R et al. HIF-1alpha and HIF-2alpha are differentially regulated in vivo in neuroblastoma: high HIF-1alpha correlates negatively to advanced clinical stage and tumor vascularization. Clin. Cancer Res. 2009 Dec;15(23):7130-6
Noguera R et al
2009/01/01
Applications: PubMed
21 Sun HX et al. Hypoxia inducible factor 2 alpha inhibits hepatocellular carcinoma growth through the transcription factor dimerization partner 3/ E2F transcription factor 1-dependent apoptotic pathway. Hepatology 2013 Mar;57(3):1088-97
Sun HX et al
2013/01/01
Species: Human, Applications: ICC/IF PubMed
22 Giatromanolaki A et al. Expression of hypoxia-inducible carbonic anhydrase-9 relates to angiogenic pathways and independently to poor outcome in non-small cell lung cancer. Cancer Res. 2001 Nov;61(21):7992-8
Giatromanolaki A et al
2001/01/01
Species: Human, Applications: IHC-P PubMed
23 Beasley NJ et al. Hypoxia-inducible factors HIF-1alpha and HIF-2alpha in head and neck cancer: relationship to tumor biology and treatment outcome in surgically resected patients. Cancer Res. 2002 May;62(9):2493-7
Beasley NJ et al
2002/01/01
Species: Human, Applications: IHC-P PubMed
24 Koukourakis MI et al. Hypoxia inducible factor (HIF-1a and HIF-2a) expression in early esophageal cancer and response to photodynamic therapy and radiotherapy. Cancer Res. 2001 Mar;61(5):1830-2
Koukourakis MI et al
2001/01/01
Species: Human, Applications: IHC-P PubMed
25 Figlin RA et al. Analysis of PTEN and HIF-1alpha and correlation with efficacy in patients with advanced renal cell carcinoma treated with temsirolimus versus interferon-alpha. Cancer 2009 Aug;115(16):3651-60
Figlin RA et al
2009/01/01
Species: Human, Applications: IHC-P PubMed
26 Kucharzewska P et al. Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development. Proc. Natl. Acad. Sci. U.S.A. 2013 Apr;110(18):7312-7
Kucharzewska P et al
2013/01/01
Species: Human, Applications: WB PubMed
27 Zheng X et al. Cell-type-specific regulation of degradation of hypoxia-inducible factor 1 alpha: role of subcellular compartmentalization. Mol. Cell. Biol. 2006 Jun;26(12):4628-41
Zheng X et al
2006/01/01
Applications: PubMed
28 Holland WS et al. Evaluating rational non-cross-resistant combination therapy in advanced clear cell renal cell carcinoma: combined mTOR and AKT inhibitor therapy. Cancer Chemother. Pharmacol. 2012 Jan;69(1):185-94
Holland WS et al
2012/01/01
Species: Human, Applications: WB PubMed
29 Lim CS et al. The effects of doxycycline and micronized purified flavonoid fraction on human vein wall remodeling are not hypoxia-inducible factor pathway-dependent. J. Vasc. Surg. 2012 Oct;56(4):1069-77
Lim CS et al
2012/01/01
Species: Human, Applications: WB PubMed
30 Chintalapudi MR et al. Cyr61/CCN1 and CTGF/CCN2 mediate the proangiogenic activity of VHL-mutant renal carcinoma cells. Carcinogenesis 2008 Apr;29(4):696-703
Chintalapudi MR et al
2008/01/01
Applications: PubMed
31 Rasheed S et al. Hypoxia-inducible factor-1alpha and -2alpha are expressed in most rectal cancers but only hypoxia-inducible factor-1alpha is associated with prognosis. Br. J. Cancer 2009 May;100(10):1666-73
Rasheed S et al
2009/01/01
Species: Human, Applications: IHC-P PubMed
32 Shinojima T et al. Renal cancer cells lacking hypoxia inducible factor (HIF)-1alpha expression maintain vascular endothelial growth factor expression through HIF-2alpha. Carcinogenesis 2007 Mar;28(3):529-36
Shinojima T et al
2007/01/01
Applications: WB PubMed
33 Ndubuizu OI et al. Increased prolyl 4-hydroxylase expression and differential regulation of hypoxia-inducible factors in the aged rat brain. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2009 Jul;297(1):R158-65
Ndubuizu OI et al
2009/01/01
Applications: PubMed
34 Wacker I et al. Key role for activin B in cellular transformation after loss of the von Hippel-Lindau tumor suppressor. Mol. Cell. Biol. 2009 Apr;29(7):1707-18
Wacker I et al
2009/01/01
Applications: PubMed
35 Tuller ER et al. Docosahexaenoic acid inhibits superoxide dismutase 1 gene transcription in human cancer cells: the involvement of peroxisome proliferator-activated receptor alpha and hypoxia-inducible factor-2alpha signaling. Mol. Pharmacol. 2009 Sep;76(
Tuller ER et al
2009/01/01
Applications: PubMed
36 Taylor M et al. Hypoxia-inducible factor-2&#x3B1; mediates the adaptive increase of intestinal ferroportin during iron deficiency in mice. Gastroenterology 2011 Jun;140(7):2044-55
Taylor M et al
2011/01/01
Species: Mouse, Applications: WB, ChIP PubMed
37 Kubo T et al. Expression of hypoxia-inducible factor-1alpha and its relationship to tumour angiogenesis and cell proliferation in cartilage tumours. J Bone Joint Surg Br 2008 Mar;90(3):364-70
Kubo T et al
2008/01/01
Applications: WB PubMed
38 Poey ME et al. Virulence profiles in uropathogenic Escherichia coli isolated from pregnant women and children with urinary tract abnormalities. Microb. Pathog. 2012 May;52(5):292-301
Poey ME et al
2012/01/01
Species: Human, Applications: WB PubMed
39 Klotzsche-von Ameln A et al. PHD4 stimulates tumor angiogenesis in osteosarcoma cells via TGF-&#x3B1;. Mol. Cancer Res. 2013 Nov;11(11):1337-48
Klotzsche-von Ameln A et al
2013/01/01
Species: Human, Applications: WB PubMed
40 Pastorino F et al. Tumor regression and curability of preclinical neuroblastoma models by PEGylated SN38 (EZN-2208), a novel topoisomerase I inhibitor. Clin. Cancer Res. 2010 Oct;16(19):4809-21
Pastorino F et al
2010/01/01
Species: Human, Applications: WB PubMed
41 Duan LJ et al. Hypoxia inducible factor-2&#x3B1; regulates the development of retinal astrocytic network by maintaining adequate supply of astrocyte progenitors. PLoS ONE 2014;9(1):e84736
Duan LJ et al
2014/01/01
Species: Mouse, Applications: WB PubMed
42 Eul B et al. Impact of HIF-1alpha and HIF-2alpha on proliferation and migration of human pulmonary artery fibroblasts in hypoxia. FASEB J. 2006 Jan;20(1):163-5
Eul B et al
2006/01/01
Applications: PubMed
43 Persano L et al. BMP2 sensitizes glioblastoma stem-like cells to Temozolomide by affecting HIF-1&#x3B1; stability and MGMT expression. Cell Death Dis 2012;3:e412
Persano L et al
2012/01/01
Species: Human, Applications: WB, ChIP PubMed
44 Gregg JL et al. NADPH oxidase NOX4 supports renal tumorigenesis by promoting the expression and nuclear accumulation of HIF2&#x3B1;. Cancer Res. 2014 Jul;74(13):3501-11
Gregg JL et al
2014/01/01
Species: Human, Applications: ICC/IF, IHC-P, WB PubMed
45 Bougatef F et al. EMMPRIN promotes melanoma cells malignant properties through a HIF-2alpha mediated up-regulation of VEGF-receptor-2. PLoS ONE 2010;5(8):e12265
Bougatef F et al
2010/01/01
Species: Human, Applications: WB, ICC/IF, IHC PubMed
46 Volke M et al. Evidence for a lack of a direct transcriptional suppression of the iron regulatory peptide hepcidin by hypoxia-inducible factors. PLoS ONE 2009;4(11):e7875
Volke M et al
2009/01/01
Species: Human, Applications: WB PubMed
47 Nakajima T et al. Concerted inhibition of HIF-1&#x3B1; and -2&#x3B1; expression markedly suppresses angiogenesis in cultured RPE cells. Mol. Cell. Biochem. 2013 Jul;
Nakajima T et al
2013/01/01
Species: Human, Applications: WB PubMed
48 Walter A et al. Red wine polyphenols prevent acceleration of neovascularization by angiotensin II in the ischemic rat hindlimb. J. Pharmacol. Exp. Ther. 2009 May;329(2):699-707
Walter A et al
2009/01/01
Applications: PubMed
49 Chen T et al. Loss of MicroRNA-17&#x223C;92 in Smooth Muscle Cells Attenuates Experimental Pulmonary Hypertension via Induction of PDZ and LIM Domain 5. Am. J. Respir. Crit. Care Med. 2015 Mar;191(6):678-92
Chen T et al
2015/01/01
Species: Human, Applications: WB PubMed
50 Muratsu-Ikeda S et al. Downregulation of miR-205 modulates cell susceptibility to oxidative and endoplasmic reticulum stresses in renal tubular cells. PLoS ONE 2012;7(7):e41462
Muratsu-Ikeda S et al
2012/01/01
Species: Human, Applications: WB PubMed
51 Tsang WP et al. CD146+ human umbilical cord perivascular cells maintain stemness under hypoxia and as a cell source for skeletal regeneration. PLoS ONE 2013;8(10):e76153
Tsang WP et al
2013/01/01
Species: Human, Applications: WB PubMed
52 Jeong CW et al. The Role of Hypoxia-Inducible Factor-1&#x3B1; and -2&#x3B1; in Androgen Insensitive Prostate Cancer Cells. Urol Oncol 2012 Apr;
Jeong CW et al
2012/01/01
Species: Human, Applications: WB PubMed
53 Place TL et al. Aberrant promoter CpG methylation is a mechanism for impaired PHD3 expression in a diverse set of malignant cells. PLoS ONE 2011;6(1):e14617
Place TL et al
2011/01/01
Species: Human, Applications: WB PubMed
54 Peng YJ et al. Regulation of hypoxia-inducible factor-&#x3B1; isoforms and redox state by carotid body neural activity in rats. J. Physiol. (Lond.) 2014 Sep;592(Pt 17):3841-58
Peng YJ et al
2014/01/01
Species: Rat, Applications: IHC-Fr, WB PubMed
55 Martin SK et al. Hypoxia-inducible factor-2 is a novel regulator of aberrant CXCL12 expression in multiple myeloma plasma cells. Haematologica 2010 May;95(5):776-84
Martin SK et al
2010/01/01
Applications: PubMed
56 Duan LJ et al. Hematological, hepatic, and retinal phenotypes in mice deficient for prolyl hydroxylase domain proteins in the liver. Am. J. Pathol. 2014 Apr;184(4):1240-50
Duan LJ et al
2014/01/01
Species: Mouse, Applications: WB PubMed
57 David JM et al. Gramicidin A induces metabolic dysfunction and energy depletion leading to cell death in renal cell carcinoma cells. Mol. Cancer Ther. 2013 Nov;12(11):2296-307
David JM et al
2013/01/01
Applications: PubMed
58 Mihaylova S et al. Effects of anti-inflammatory vagus nerve stimulation on the cerebral microcirculation in endotoxinemic rats. J Neuroinflammation 2012;9:183
Mihaylova S et al
2012/01/01
Species: Rat, Applications: WB PubMed
59 Li Q et al. GSK-3&#x3B2;: a signaling pathway node modulating neural stem cell and endothelial cell interactions. Angiogenesis 2011 May;14(2):173-85
Li Q et al
2011/01/01
Species: Mouse, Applications: WB PubMed
60 Bruells CS et al. Prolonged mechanical ventilation alters the expression pattern of angio-neogenetic factors in a pre-clinical rat model. PLoS ONE 2013;8(8):e70524
Bruells CS et al
2013/01/01
Species: Rat, Applications: WB PubMed
61 Bangiyeva V et al. Differences in regulation of tight junctions and cell morphology between VHL mutations from disease subtypes. BMC Cancer 2009;9:229
Bangiyeva V et al
2009/01/01
Applications: PubMed
62 Harvey AJ et al. Regulation of gene expression in bovine blastocysts in response to oxygen and the iron chelator desferrioxamine. Biol. Reprod. 2007 Jul;77(1):93-101
Harvey AJ et al
2007/01/01
Species: Human, Applications: ICC/IF PubMed
63 Anderson ER et al. Intestinal HIF2&#x3B1; promotes tissue-iron accumulation in disorders of iron overload with anemia. Proc. Natl. Acad. Sci. U.S.A. 2013 Dec;110(50):E4922-30
Anderson ER et al
2013/01/01
Species: Mouse, Applications: WB PubMed
64 Carroll PA et al. Latent Kaposi&quot;s sarcoma-associated herpesvirus infection of endothelial cells activates hypoxia-induced factors. J. Virol. 2006 Nov;80(21):10802-12
Carroll PA et al
2006/01/01
Species: Human, Applications: IHC-P PubMed
65 Thompson AA et al. Hypoxia-inducible factor 2&#x3B1; regulates key neutrophil functions in humans, mice, and zebrafish. Blood 2014 Jan;123(3):366-76
Thompson AA et al
2014/01/01
Species: Human, Mouse, Applications: WB, IHC PubMed
66 Carrera S et al. The role of the HIF-1&#x3B1; transcription factor in increased cell division at physiological oxygen tensions. PLoS ONE 2014;9(5):e97938
Carrera S et al
2014/01/01
Species: Human, Applications: WB PubMed
67 Lee WH et al. Structural requirements within protoporphyrin IX in the inhibition of heat shock protein 90. Chem. Biol. Interact. 2013 Jun;204(1):49-57
Lee WH et al
2013/01/01
Species: Human, Applications: WB PubMed
68 Nakayama K. cAMP-response Element-binding Protein (CREB) and NF-&#x3BA;B Transcription Factors Are Activated during Prolonged Hypoxia and Cooperatively Regulate the Induction of Matrix Metalloproteinase MMP1. J. Biol. Chem. 2013 Aug;288(31):22584-95
Nakayama K
2013/01/01
Species: Human, Applications: WB PubMed
69 Chen R et al. The Acetylase/Deacetylase Couple CREB-binding Protein/Sirtuin 1 Controls Hypoxia-inducible Factor 2 Signaling. J. Biol. Chem. 2012 Aug;287(36):30800-11
Chen R et al
2012/01/01
Species: Human, Applications: IP PubMed
70 Burkitt K et al. Targeting both HIF-1 and HIF-2 in human colon cancer cells improves tumor response to sunitinib treatment. Mol. Cancer Ther. 2009 May;8(5):1148-56
Burkitt K et al
2009/01/01
Applications: PubMed
71 Jamil S et al. Neuroblastoma cells injected into experimental mature teratoma reveal a tropism for embryonic loose mesenchyme. Int. J. Oncol. 2013 Sep;43(3):831-8
Jamil S et al
2013/01/01
Applications: PubMed
72 Heikkil辰 M et al. Roles of the human hypoxia-inducible factor (HIF)-3&#x3B1; variants in the hypoxia response. Cell. Mol. Life Sci. 2011 Dec;68(23):3885-901
Heikkil辰 M et al
2011/01/01
Species: Hamster, Applications: WB PubMed
73 Park YK et al. Hypoxia-inducible Factor-2&#x3B1;-dependent Hypoxic Induction of Wnt10b Expression in Adipogenic Cells. J. Biol. Chem. 2013 Sep;288(36):26311-22
Park YK et al
2013/01/01
Species: Mouse, Applications: WB PubMed
74 Xue X et al. Hypoxia-inducible factor-2&#x3B1; is essential in activating the COX2/mPGES-1/PGE2 signaling axis in colon cancer. Carcinogenesis 2012 Nov;
Xue X et al
2012/01/01
Species: Mouse, Applications: ChIP PubMed
75 Borger DR et al. AMP-activated protein kinase is essential for survival in chronic hypoxia. Biochem. Biophys. Res. Commun. 2008 May;370(2):230-4
Borger DR et al
2008/01/01
Species: Human, Applications: WB PubMed
76 Raspaglio G et al. Sox9 and Hif-2&#x3B1; regulate TUBB3 gene expression and affect ovarian cancer aggressiveness. Gene 2014 Jun;542(2):173-81
Raspaglio G et al
2014/01/01
Species: Human, Applications: ChIP, WB PubMed
77 Kim Y et al. Hypoxia-regulated delta-like 1 homologue enhances cancer cell stemness and tumorigenicity. Cancer Res. 2009 Dec;69(24):9271-80
Kim Y et al
2009/01/01
Applications: PubMed
78 Kiss J et al. Loss of the oxygen sensor PHD3 enhances the innate immune response to abdominal sepsis. J. Immunol. 2012 Aug;189(4):1955-65
Kiss J et al
2012/01/01
Species: Mouse, Applications: WB PubMed
79 Chen R et al. The acetate/ACSS2 switch regulates HIF-2 stress signaling in the tumor cell microenvironment. PLoS ONE 2015;10(2):e0116515
Chen R et al
2015/01/01
Species: Human, Applications: WB, IP PubMed
80 Huang C et al. Effects of exposure to a DNA damaging agent on the hypoxia inducible factors in organogenesis stage mouse limbs. PLoS ONE 2012;7(12):e51937
Huang C et al
2012/01/01
Species: Mouse, Applications: WB, IHC PubMed
81 El Naggar A et al. Expression and stability of hypoxia inducible factor 1&#x3B1; in osteosarcoma. Pediatr Blood Cancer 2012 Dec;59(7):1215-22
El Naggar A et al
2012/01/01
Species: Human, Applications: WB PubMed
82 Gottfried E et al. New aspects of an old drug--diclofenac targets MYC and glucose metabolism in tumor cells. PLoS ONE 2013;8(7):e66987
Gottfried E et al
2013/01/01
Species: Human, Applications: WB PubMed
83 Chen R et al. Hypoxia increases sirtuin 1 expression in a hypoxia-inducible factor-dependent manner. J. Biol. Chem. 2011 Apr;286(16):13869-78
Chen R et al
2011/01/01
Species: Human, Applications: WB, ChIP PubMed
84 Adamski J et al. Hypoxia-induced cytotoxic drug resistance in osteosarcoma is independent of HIF-1Alpha. PLoS ONE 2013;8(6):e65304
Adamski J et al
2013/01/01
Species: Human, Applications: WB PubMed
85 Husted RF et al. Oxygen regulation of the epithelial Na channel in the collecting duct. Am. J. Physiol. Renal Physiol. 2011 Feb;300(2):F412-24
Husted RF et al
2011/01/01
PubMed
86 Toyoda H et al. Polycythemia and paraganglioma with a novel somatic HIF2A mutation in a male. Pediatrics 2014 Jun;133(6):e1787-91
Toyoda H et al
2014/01/01
Species: Human, Applications: IHC-P PubMed
87 Vaapil M et al. Hypoxic conditions induce a cancer-like phenotype in human breast epithelial cells. PLoS ONE 2012;7(9):e46543
Vaapil M et al
2012/01/01
Species: Human, Applications: IHC, WB PubMed
88 Zimmer M et al. Inhibition of hypoxia-inducible factor is sufficient for growth suppression of VHL-/- tumors. Mol. Cancer Res. 2004 Feb;2(2):89-95
Zimmer M et al
2004/01/01
Applications: WB PubMed
89 Grabmaier K et al. Strict regulation of CAIX(G250/MN) by HIF-1alpha in clear cell renal cell carcinoma. Oncogene 2004 Jul;23(33):5624-31
Grabmaier K et al
2004/01/01
Species: Human PubMed
90 Imamura T et al. HIF-1alpha and HIF-2alpha have divergent roles in colon cancer. Int. J. Cancer 2009 Feb;124(4):763-71
Imamura T et al
2009/01/01
Species: Human, Applications: IHC-P, WB PubMed
91 Scheuermann TH et al. Allosteric inhibition of hypoxia inducible factor-2 with small molecules. Nat. Chem. Biol. 2013 Apr;9(4):271-6
Scheuermann TH et al
2013/01/01
Species: Human, Applications: ChIP PubMed
92 Abbruzzetti S et al. Ligand migration through the internal hydrophobic cavities in human neuroglobin. Proc. Natl. Acad. Sci. U.S.A. 2009 Nov;106(45):18984-9
Abbruzzetti S et al
2009/01/01
PubMed
93 Arvidsson Y et al. Hypoxia stimulates CXCR4 signalling in ileal carcinoids. Endocr. Relat. Cancer 2010 Jun;17(2):303-16
Arvidsson Y et al
2010/01/01
Species: Human, Applications: IHC PubMed
94 Sutphin PD et al. Targeting the loss of the von Hippel-Lindau tumor suppressor gene in renal cell carcinoma cells. Cancer Res. 2007 Jun;67(12):5896-905
Sutphin PD et al
2007/01/01
PubMed
95 Thomas S et al. CD24 Is an Effector of HIF-1-Driven Primary Tumor Growth and Metastasis. Cancer Res. 2012 Nov;72(21):5600-12
Thomas S et al
2012/01/01
Species: Human, Applications: WB PubMed
96 Demachi-Okamura A et al. Autophagy Creates a CTL Epitope That Mimics Tumor-Associated Antigens. PLoS ONE 2012;7(10):e47126
Demachi-Okamura A et al
2012/01/01
Species: Human, Applications: WB PubMed
97 Yeh IJ et al. HEXIM1 down-regulates hypoxia-inducible factor-1&#x3B1; protein stability. Biochem. J. 2013 Dec;456(2):195-204
Yeh IJ et al
2013/01/01
Species: Human, Applications: WB PubMed
98 Havasi A et al. Histone acetyl transferase (HAT) HBO1 and JADE1 in epithelial cell regeneration. Am. J. Pathol. 2013 Jan;182(1):152-62
Havasi A et al
2013/01/01
PubMed
99 Lin Q et al. Differential hypoxic regulation of hypoxia-inducible factors 1alpha and 2alpha. Mol. Cancer Res. 2011 Jun;9(6):757-65
Lin Q et al
2011/01/01
Species: Human, Applications: WB PubMed
100 Macaulay IC et al. Canonical Wnt signaling in megakaryocytes regulates proplatelet formation. Blood 2013 Jan;121(1):188-96
Macaulay IC et al
2013/01/01
PubMed
101 Zhang T et al. The contributions of HIF-target genes to tumor growth in RCC. PLoS ONE 2013;8(11):e80544
Zhang T et al
2013/01/01
Species: Human, Applications: WB PubMed
102 Xu M et al. An acetate switch regulates stress erythropoiesis. Nat. Med. 2014 Sep;20(9):1018-26
Xu M et al
2014/01/01
Species: Human, Applications: WB, ChIP, IP PubMed
103 Xia G et al. Positive expression of HIF-2alpha/EPAS1 in invasive bladder cancer. Urology 2002 May;59(5):774-8
Xia G et al
2002/01/01
PubMed
104 Talks KL et al. The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages. Am. J. Pathol. 2000 Aug;157(2):411-21
Talks KL et al
2000/01/01
Applications: WB, IHC PubMed
105 Blancher C et al. Relationship of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression to vascular endothelial growth factor induction and hypoxia survival in human breast cancer cell lines. Cancer Res. 2000 Dec;60(24):7106-13
Blancher C et al
2000/01/01
Applications: WB, IHC PubMed
  • No.: 1
  • 文献情報:
    Mohan S et al. von Hippel-Lindau protein complex is regulated by cell density. Oncogene 2003 Aug;22(34):5270-80
    Mohan S et al
    2003/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 2
  • 文献情報:
    Pan Y et al. p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment. Oncogene 2004 Jun;23(29):4975-83
    Pan Y et al
    2004/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 3
  • 文献情報:
    Tissot van Patot MC et al. Greater vascularity, lowered HIF-1/DNA binding, and elevated GSH as markers of adaptation to in vivo chronic hypoxia. Am. J. Physiol. Lung Cell Mol. Physiol. 2004 Sep;287(3):L525-32
    Tissot van Patot MC et al
    2004/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 4
  • 文献情報:
    Koike T et al. Hypoxia induces adhesion molecules on cancer cells: A missing link between Warburg effect and induction of selectin-ligand carbohydrates. Proc. Natl. Acad. Sci. U.S.A. 2004 May;101(21):8132-7
    Koike T et al
    2004/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 5
  • 文献情報:
    Harvey AJ et al. Oxygen-regulated gene expression in bovine blastocysts. Biol. Reprod. 2004 Oct;71(4):1108-19
    Harvey AJ et al
    2004/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 6
  • 文献情報:
    Mekhail K et al. HIF activation by pH-dependent nucleolar sequestration of VHL. Nat. Cell Biol. 2004 Jul;6(7):642-7
    Mekhail K et al
    2004/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 7
  • 文献情報:
    Rathmell WK et al. In vitro and in vivo models analyzing von Hippel-Lindau disease-specific mutations. Cancer Res. 2004 Dec;64(23):8595-603
    Rathmell WK et al
    2004/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 8
  • 文献情報:
    Yoshimura H et al. Prognostic impact of hypoxia-inducible factors 1alpha and 2alpha in colorectal cancer patients: correlation with tumor angiogenesis and cyclooxygenase-2 expression. Clin. Cancer Res. 2004 Dec;10(24):8554-60
    Yoshimura H et al
    2004/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 9
  • 文献情報:
    Li L et al. Evaluating hypoxia-inducible factor-1alpha as a cancer therapeutic target via inducible RNA interference in vivo. Cancer Res. 2005 Aug;65(16):7249-58
    Li L et al
    2005/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 10
  • 文献情報:
    Nakamura E et al. Clusterin is a secreted marker for a hypoxia-inducible factor-independent function of the von Hippel-Lindau tumor suppressor protein. Am. J. Pathol. 2006 Feb;168(2):574-84
    Nakamura E et al
    2006/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 11
  • 文献情報:
    Koizume S et al. Activation of cancer cell migration and invasion by ectopic synthesis of coagulation factor VII. Cancer Res. 2006 Oct;66(19):9453-60
    Koizume S et al
    2006/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 12
  • 文献情報:
    Yan Q et al. The hypoxia-inducible factor 2alpha N-terminal and C-terminal transactivation domains cooperate to promote renal tumorigenesis in vivo. Mol. Cell. Biol. 2007 Mar;27(6):2092-102
    Yan Q et al
    2007/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 13
  • 文献情報:
    Bernhardt WM et al. Involvement of hypoxia-inducible transcription factors in polycystic kidney disease. Am. J. Pathol. 2007 Mar;170(3):830-42
    Bernhardt WM et al
    2007/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 14
  • 文献情報:
    Evans CE et al. Local accumulation of hypoxia-inducible factor 2 alpha during venous thrombus resolution. Thromb. Res. 2014 Sep;134(3):757-60
    Evans CE et al
    2014/01/01
  • 備考:
    Species: Mouse, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 15
  • 文献情報:
    Lee DW et al. Inhibition of prolyl hydroxylase protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity: model for the potential involvement of the hypoxia-inducible factor pathway in Parkinson disease. J. Biol. Chem. 2009 Oct;2
    Lee DW et al
    2009/01/01
  • 備考:
    Applications:
  • 参照:
    PubMed
  • No.: 16
  • 文献情報:
    Wiesener MS et al. Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha. Blood 1998 Oct;92(7):2260-8
    Wiesener MS et al
    1998/01/01
  • 備考:
    Applications:
  • 参照:
    PubMed
  • No.: 17
  • 文献情報:
    Mart鱈n-Puig S et al. Role of iron (II)-2-oxoglutarate-dependent dioxygenases in the generation of hypoxia-induced phosphatidic acid through HIF-1/2 and von Hippel-Lindau-independent mechanisms. J. Biol. Chem. 2004 Mar;279(10):9504-11
    Mart鱈n-Puig S et al
    2004/01/01
  • 備考:
    Applications:
  • 参照:
    PubMed
  • No.: 18
  • 文献情報:
    Fukui N et al. Development of a novel interferon-&#x3B1;2b gene construct with a repetitive hypoxia-inducible factor binding site and its suppressive effects on human renal cell carcinoma cell lines in vitro. Int. J. Clin. Oncol. 2013 Jun;
    Fukui N et al
    2013/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 19
  • 文献情報:
    Munksgaard Persson M et al. HIF-2&#x3B1; expression is suppressed in SCLC cells, which survive in moderate and severe hypoxia when HIF-1&#x3B1; is repressed. Am. J. Pathol. 2012 Feb;180(2):494-504
    Munksgaard Persson M et al
    2012/01/01
  • 備考:
    Applications:
  • 参照:
    PubMed
  • No.: 20
  • 文献情報:
    Noguera R et al. HIF-1alpha and HIF-2alpha are differentially regulated in vivo in neuroblastoma: high HIF-1alpha correlates negatively to advanced clinical stage and tumor vascularization. Clin. Cancer Res. 2009 Dec;15(23):7130-6
    Noguera R et al
    2009/01/01
  • 備考:
    Applications:
  • 参照:
    PubMed
  • No.: 21
  • 文献情報:
    Sun HX et al. Hypoxia inducible factor 2 alpha inhibits hepatocellular carcinoma growth through the transcription factor dimerization partner 3/ E2F transcription factor 1-dependent apoptotic pathway. Hepatology 2013 Mar;57(3):1088-97
    Sun HX et al
    2013/01/01
  • 備考:
    Species: Human, Applications: ICC/IF
  • 参照:
    PubMed
  • No.: 22
  • 文献情報:
    Giatromanolaki A et al. Expression of hypoxia-inducible carbonic anhydrase-9 relates to angiogenic pathways and independently to poor outcome in non-small cell lung cancer. Cancer Res. 2001 Nov;61(21):7992-8
    Giatromanolaki A et al
    2001/01/01
  • 備考:
    Species: Human, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 23
  • 文献情報:
    Beasley NJ et al. Hypoxia-inducible factors HIF-1alpha and HIF-2alpha in head and neck cancer: relationship to tumor biology and treatment outcome in surgically resected patients. Cancer Res. 2002 May;62(9):2493-7
    Beasley NJ et al
    2002/01/01
  • 備考:
    Species: Human, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 24
  • 文献情報:
    Koukourakis MI et al. Hypoxia inducible factor (HIF-1a and HIF-2a) expression in early esophageal cancer and response to photodynamic therapy and radiotherapy. Cancer Res. 2001 Mar;61(5):1830-2
    Koukourakis MI et al
    2001/01/01
  • 備考:
    Species: Human, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 25
  • 文献情報:
    Figlin RA et al. Analysis of PTEN and HIF-1alpha and correlation with efficacy in patients with advanced renal cell carcinoma treated with temsirolimus versus interferon-alpha. Cancer 2009 Aug;115(16):3651-60
    Figlin RA et al
    2009/01/01
  • 備考:
    Species: Human, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 26
  • 文献情報:
    Kucharzewska P et al. Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development. Proc. Natl. Acad. Sci. U.S.A. 2013 Apr;110(18):7312-7
    Kucharzewska P et al
    2013/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 27
  • 文献情報:
    Zheng X et al. Cell-type-specific regulation of degradation of hypoxia-inducible factor 1 alpha: role of subcellular compartmentalization. Mol. Cell. Biol. 2006 Jun;26(12):4628-41
    Zheng X et al
    2006/01/01
  • 備考:
    Applications:
  • 参照:
    PubMed
  • No.: 28
  • 文献情報:
    Holland WS et al. Evaluating rational non-cross-resistant combination therapy in advanced clear cell renal cell carcinoma: combined mTOR and AKT inhibitor therapy. Cancer Chemother. Pharmacol. 2012 Jan;69(1):185-94
    Holland WS et al
    2012/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 29
  • 文献情報:
    Lim CS et al. The effects of doxycycline and micronized purified flavonoid fraction on human vein wall remodeling are not hypoxia-inducible factor pathway-dependent. J. Vasc. Surg. 2012 Oct;56(4):1069-77
    Lim CS et al
    2012/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 30
  • 文献情報:
    Chintalapudi MR et al. Cyr61/CCN1 and CTGF/CCN2 mediate the proangiogenic activity of VHL-mutant renal carcinoma cells. Carcinogenesis 2008 Apr;29(4):696-703
    Chintalapudi MR et al
    2008/01/01
  • 備考:
    Applications:
  • 参照:
    PubMed
  • No.: 31
  • 文献情報:
    Rasheed S et al. Hypoxia-inducible factor-1alpha and -2alpha are expressed in most rectal cancers but only hypoxia-inducible factor-1alpha is associated with prognosis. Br. J. Cancer 2009 May;100(10):1666-73
    Rasheed S et al
    2009/01/01
  • 備考:
    Species: Human, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 32
  • 文献情報:
    Shinojima T et al. Renal cancer cells lacking hypoxia inducible factor (HIF)-1alpha expression maintain vascular endothelial growth factor expression through HIF-2alpha. Carcinogenesis 2007 Mar;28(3):529-36
    Shinojima T et al
    2007/01/01
  • 備考:
    Applications: WB
  • 参照:
    PubMed
  • No.: 33
  • 文献情報:
    Ndubuizu OI et al. Increased prolyl 4-hydroxylase expression and differential regulation of hypoxia-inducible factors in the aged rat brain. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2009 Jul;297(1):R158-65
    Ndubuizu OI et al
    2009/01/01
  • 備考:
    Applications:
  • 参照:
    PubMed
  • No.: 34
  • 文献情報:
    Wacker I et al. Key role for activin B in cellular transformation after loss of the von Hippel-Lindau tumor suppressor. Mol. Cell. Biol. 2009 Apr;29(7):1707-18
    Wacker I et al
    2009/01/01
  • 備考:
    Applications:
  • 参照:
    PubMed
  • No.: 35
  • 文献情報:
    Tuller ER et al. Docosahexaenoic acid inhibits superoxide dismutase 1 gene transcription in human cancer cells: the involvement of peroxisome proliferator-activated receptor alpha and hypoxia-inducible factor-2alpha signaling. Mol. Pharmacol. 2009 Sep;76(
    Tuller ER et al
    2009/01/01
  • 備考:
    Applications:
  • 参照:
    PubMed
  • No.: 36
  • 文献情報:
    Taylor M et al. Hypoxia-inducible factor-2&#x3B1; mediates the adaptive increase of intestinal ferroportin during iron deficiency in mice. Gastroenterology 2011 Jun;140(7):2044-55
    Taylor M et al
    2011/01/01
  • 備考:
    Species: Mouse, Applications: WB, ChIP
  • 参照:
    PubMed
  • No.: 37
  • 文献情報:
    Kubo T et al. Expression of hypoxia-inducible factor-1alpha and its relationship to tumour angiogenesis and cell proliferation in cartilage tumours. J Bone Joint Surg Br 2008 Mar;90(3):364-70
    Kubo T et al
    2008/01/01
  • 備考:
    Applications: WB
  • 参照:
    PubMed
  • No.: 38
  • 文献情報:
    Poey ME et al. Virulence profiles in uropathogenic Escherichia coli isolated from pregnant women and children with urinary tract abnormalities. Microb. Pathog. 2012 May;52(5):292-301
    Poey ME et al
    2012/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 39
  • 文献情報:
    Klotzsche-von Ameln A et al. PHD4 stimulates tumor angiogenesis in osteosarcoma cells via TGF-&#x3B1;. Mol. Cancer Res. 2013 Nov;11(11):1337-48
    Klotzsche-von Ameln A et al
    2013/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 40
  • 文献情報:
    Pastorino F et al. Tumor regression and curability of preclinical neuroblastoma models by PEGylated SN38 (EZN-2208), a novel topoisomerase I inhibitor. Clin. Cancer Res. 2010 Oct;16(19):4809-21
    Pastorino F et al
    2010/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 41
  • 文献情報:
    Duan LJ et al. Hypoxia inducible factor-2&#x3B1; regulates the development of retinal astrocytic network by maintaining adequate supply of astrocyte progenitors. PLoS ONE 2014;9(1):e84736
    Duan LJ et al
    2014/01/01
  • 備考:
    Species: Mouse, Applications: WB
  • 参照:
    PubMed
  • No.: 42
  • 文献情報:
    Eul B et al. Impact of HIF-1alpha and HIF-2alpha on proliferation and migration of human pulmonary artery fibroblasts in hypoxia. FASEB J. 2006 Jan;20(1):163-5
    Eul B et al
    2006/01/01
  • 備考:
    Applications:
  • 参照:
    PubMed
  • No.: 43
  • 文献情報:
    Persano L et al. BMP2 sensitizes glioblastoma stem-like cells to Temozolomide by affecting HIF-1&#x3B1; stability and MGMT expression. Cell Death Dis 2012;3:e412
    Persano L et al
    2012/01/01
  • 備考:
    Species: Human, Applications: WB, ChIP
  • 参照:
    PubMed
  • No.: 44
  • 文献情報:
    Gregg JL et al. NADPH oxidase NOX4 supports renal tumorigenesis by promoting the expression and nuclear accumulation of HIF2&#x3B1;. Cancer Res. 2014 Jul;74(13):3501-11
    Gregg JL et al
    2014/01/01
  • 備考:
    Species: Human, Applications: ICC/IF, IHC-P, WB
  • 参照:
    PubMed
  • No.: 45
  • 文献情報:
    Bougatef F et al. EMMPRIN promotes melanoma cells malignant properties through a HIF-2alpha mediated up-regulation of VEGF-receptor-2. PLoS ONE 2010;5(8):e12265
    Bougatef F et al
    2010/01/01
  • 備考:
    Species: Human, Applications: WB, ICC/IF, IHC
  • 参照:
    PubMed
  • No.: 46
  • 文献情報:
    Volke M et al. Evidence for a lack of a direct transcriptional suppression of the iron regulatory peptide hepcidin by hypoxia-inducible factors. PLoS ONE 2009;4(11):e7875
    Volke M et al
    2009/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 47
  • 文献情報:
    Nakajima T et al. Concerted inhibition of HIF-1&#x3B1; and -2&#x3B1; expression markedly suppresses angiogenesis in cultured RPE cells. Mol. Cell. Biochem. 2013 Jul;
    Nakajima T et al
    2013/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 48
  • 文献情報:
    Walter A et al. Red wine polyphenols prevent acceleration of neovascularization by angiotensin II in the ischemic rat hindlimb. J. Pharmacol. Exp. Ther. 2009 May;329(2):699-707
    Walter A et al
    2009/01/01
  • 備考:
    Applications:
  • 参照:
    PubMed
  • No.: 49
  • 文献情報:
    Chen T et al. Loss of MicroRNA-17&#x223C;92 in Smooth Muscle Cells Attenuates Experimental Pulmonary Hypertension via Induction of PDZ and LIM Domain 5. Am. J. Respir. Crit. Care Med. 2015 Mar;191(6):678-92
    Chen T et al
    2015/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 50
  • 文献情報:
    Muratsu-Ikeda S et al. Downregulation of miR-205 modulates cell susceptibility to oxidative and endoplasmic reticulum stresses in renal tubular cells. PLoS ONE 2012;7(7):e41462
    Muratsu-Ikeda S et al
    2012/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 51
  • 文献情報:
    Tsang WP et al. CD146+ human umbilical cord perivascular cells maintain stemness under hypoxia and as a cell source for skeletal regeneration. PLoS ONE 2013;8(10):e76153
    Tsang WP et al
    2013/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 52
  • 文献情報:
    Jeong CW et al. The Role of Hypoxia-Inducible Factor-1&#x3B1; and -2&#x3B1; in Androgen Insensitive Prostate Cancer Cells. Urol Oncol 2012 Apr;
    Jeong CW et al
    2012/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 53
  • 文献情報:
    Place TL et al. Aberrant promoter CpG methylation is a mechanism for impaired PHD3 expression in a diverse set of malignant cells. PLoS ONE 2011;6(1):e14617
    Place TL et al
    2011/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 54
  • 文献情報:
    Peng YJ et al. Regulation of hypoxia-inducible factor-&#x3B1; isoforms and redox state by carotid body neural activity in rats. J. Physiol. (Lond.) 2014 Sep;592(Pt 17):3841-58
    Peng YJ et al
    2014/01/01
  • 備考:
    Species: Rat, Applications: IHC-Fr, WB
  • 参照:
    PubMed
  • No.: 55
  • 文献情報:
    Martin SK et al. Hypoxia-inducible factor-2 is a novel regulator of aberrant CXCL12 expression in multiple myeloma plasma cells. Haematologica 2010 May;95(5):776-84
    Martin SK et al
    2010/01/01
  • 備考:
    Applications:
  • 参照:
    PubMed
  • No.: 56
  • 文献情報:
    Duan LJ et al. Hematological, hepatic, and retinal phenotypes in mice deficient for prolyl hydroxylase domain proteins in the liver. Am. J. Pathol. 2014 Apr;184(4):1240-50
    Duan LJ et al
    2014/01/01
  • 備考:
    Species: Mouse, Applications: WB
  • 参照:
    PubMed
  • No.: 57
  • 文献情報:
    David JM et al. Gramicidin A induces metabolic dysfunction and energy depletion leading to cell death in renal cell carcinoma cells. Mol. Cancer Ther. 2013 Nov;12(11):2296-307
    David JM et al
    2013/01/01
  • 備考:
    Applications:
  • 参照:
    PubMed
  • No.: 58
  • 文献情報:
    Mihaylova S et al. Effects of anti-inflammatory vagus nerve stimulation on the cerebral microcirculation in endotoxinemic rats. J Neuroinflammation 2012;9:183
    Mihaylova S et al
    2012/01/01
  • 備考:
    Species: Rat, Applications: WB
  • 参照:
    PubMed
  • No.: 59
  • 文献情報:
    Li Q et al. GSK-3&#x3B2;: a signaling pathway node modulating neural stem cell and endothelial cell interactions. Angiogenesis 2011 May;14(2):173-85
    Li Q et al
    2011/01/01
  • 備考:
    Species: Mouse, Applications: WB
  • 参照:
    PubMed
  • No.: 60
  • 文献情報:
    Bruells CS et al. Prolonged mechanical ventilation alters the expression pattern of angio-neogenetic factors in a pre-clinical rat model. PLoS ONE 2013;8(8):e70524
    Bruells CS et al
    2013/01/01
  • 備考:
    Species: Rat, Applications: WB
  • 参照:
    PubMed
  • No.: 61
  • 文献情報:
    Bangiyeva V et al. Differences in regulation of tight junctions and cell morphology between VHL mutations from disease subtypes. BMC Cancer 2009;9:229
    Bangiyeva V et al
    2009/01/01
  • 備考:
    Applications:
  • 参照:
    PubMed
  • No.: 62
  • 文献情報:
    Harvey AJ et al. Regulation of gene expression in bovine blastocysts in response to oxygen and the iron chelator desferrioxamine. Biol. Reprod. 2007 Jul;77(1):93-101
    Harvey AJ et al
    2007/01/01
  • 備考:
    Species: Human, Applications: ICC/IF
  • 参照:
    PubMed
  • No.: 63
  • 文献情報:
    Anderson ER et al. Intestinal HIF2&#x3B1; promotes tissue-iron accumulation in disorders of iron overload with anemia. Proc. Natl. Acad. Sci. U.S.A. 2013 Dec;110(50):E4922-30
    Anderson ER et al
    2013/01/01
  • 備考:
    Species: Mouse, Applications: WB
  • 参照:
    PubMed
  • No.: 64
  • 文献情報:
    Carroll PA et al. Latent Kaposi&quot;s sarcoma-associated herpesvirus infection of endothelial cells activates hypoxia-induced factors. J. Virol. 2006 Nov;80(21):10802-12
    Carroll PA et al
    2006/01/01
  • 備考:
    Species: Human, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 65
  • 文献情報:
    Thompson AA et al. Hypoxia-inducible factor 2&#x3B1; regulates key neutrophil functions in humans, mice, and zebrafish. Blood 2014 Jan;123(3):366-76
    Thompson AA et al
    2014/01/01
  • 備考:
    Species: Human, Mouse, Applications: WB, IHC
  • 参照:
    PubMed
  • No.: 66
  • 文献情報:
    Carrera S et al. The role of the HIF-1&#x3B1; transcription factor in increased cell division at physiological oxygen tensions. PLoS ONE 2014;9(5):e97938
    Carrera S et al
    2014/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 67
  • 文献情報:
    Lee WH et al. Structural requirements within protoporphyrin IX in the inhibition of heat shock protein 90. Chem. Biol. Interact. 2013 Jun;204(1):49-57
    Lee WH et al
    2013/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 68
  • 文献情報:
    Nakayama K. cAMP-response Element-binding Protein (CREB) and NF-&#x3BA;B Transcription Factors Are Activated during Prolonged Hypoxia and Cooperatively Regulate the Induction of Matrix Metalloproteinase MMP1. J. Biol. Chem. 2013 Aug;288(31):22584-95
    Nakayama K
    2013/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 69
  • 文献情報:
    Chen R et al. The Acetylase/Deacetylase Couple CREB-binding Protein/Sirtuin 1 Controls Hypoxia-inducible Factor 2 Signaling. J. Biol. Chem. 2012 Aug;287(36):30800-11
    Chen R et al
    2012/01/01
  • 備考:
    Species: Human, Applications: IP
  • 参照:
    PubMed
  • No.: 70
  • 文献情報:
    Burkitt K et al. Targeting both HIF-1 and HIF-2 in human colon cancer cells improves tumor response to sunitinib treatment. Mol. Cancer Ther. 2009 May;8(5):1148-56
    Burkitt K et al
    2009/01/01
  • 備考:
    Applications:
  • 参照:
    PubMed
  • No.: 71
  • 文献情報:
    Jamil S et al. Neuroblastoma cells injected into experimental mature teratoma reveal a tropism for embryonic loose mesenchyme. Int. J. Oncol. 2013 Sep;43(3):831-8
    Jamil S et al
    2013/01/01
  • 備考:
    Applications:
  • 参照:
    PubMed
  • No.: 72
  • 文献情報:
    Heikkil辰 M et al. Roles of the human hypoxia-inducible factor (HIF)-3&#x3B1; variants in the hypoxia response. Cell. Mol. Life Sci. 2011 Dec;68(23):3885-901
    Heikkil辰 M et al
    2011/01/01
  • 備考:
    Species: Hamster, Applications: WB
  • 参照:
    PubMed
  • No.: 73
  • 文献情報:
    Park YK et al. Hypoxia-inducible Factor-2&#x3B1;-dependent Hypoxic Induction of Wnt10b Expression in Adipogenic Cells. J. Biol. Chem. 2013 Sep;288(36):26311-22
    Park YK et al
    2013/01/01
  • 備考:
    Species: Mouse, Applications: WB
  • 参照:
    PubMed
  • No.: 74
  • 文献情報:
    Xue X et al. Hypoxia-inducible factor-2&#x3B1; is essential in activating the COX2/mPGES-1/PGE2 signaling axis in colon cancer. Carcinogenesis 2012 Nov;
    Xue X et al
    2012/01/01
  • 備考:
    Species: Mouse, Applications: ChIP
  • 参照:
    PubMed
  • No.: 75
  • 文献情報:
    Borger DR et al. AMP-activated protein kinase is essential for survival in chronic hypoxia. Biochem. Biophys. Res. Commun. 2008 May;370(2):230-4
    Borger DR et al
    2008/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 76
  • 文献情報:
    Raspaglio G et al. Sox9 and Hif-2&#x3B1; regulate TUBB3 gene expression and affect ovarian cancer aggressiveness. Gene 2014 Jun;542(2):173-81
    Raspaglio G et al
    2014/01/01
  • 備考:
    Species: Human, Applications: ChIP, WB
  • 参照:
    PubMed
  • No.: 77
  • 文献情報:
    Kim Y et al. Hypoxia-regulated delta-like 1 homologue enhances cancer cell stemness and tumorigenicity. Cancer Res. 2009 Dec;69(24):9271-80
    Kim Y et al
    2009/01/01
  • 備考:
    Applications:
  • 参照:
    PubMed
  • No.: 78
  • 文献情報:
    Kiss J et al. Loss of the oxygen sensor PHD3 enhances the innate immune response to abdominal sepsis. J. Immunol. 2012 Aug;189(4):1955-65
    Kiss J et al
    2012/01/01
  • 備考:
    Species: Mouse, Applications: WB
  • 参照:
    PubMed
  • No.: 79
  • 文献情報:
    Chen R et al. The acetate/ACSS2 switch regulates HIF-2 stress signaling in the tumor cell microenvironment. PLoS ONE 2015;10(2):e0116515
    Chen R et al
    2015/01/01
  • 備考:
    Species: Human, Applications: WB, IP
  • 参照:
    PubMed
  • No.: 80
  • 文献情報:
    Huang C et al. Effects of exposure to a DNA damaging agent on the hypoxia inducible factors in organogenesis stage mouse limbs. PLoS ONE 2012;7(12):e51937
    Huang C et al
    2012/01/01
  • 備考:
    Species: Mouse, Applications: WB, IHC
  • 参照:
    PubMed
  • No.: 81
  • 文献情報:
    El Naggar A et al. Expression and stability of hypoxia inducible factor 1&#x3B1; in osteosarcoma. Pediatr Blood Cancer 2012 Dec;59(7):1215-22
    El Naggar A et al
    2012/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 82
  • 文献情報:
    Gottfried E et al. New aspects of an old drug--diclofenac targets MYC and glucose metabolism in tumor cells. PLoS ONE 2013;8(7):e66987
    Gottfried E et al
    2013/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 83
  • 文献情報:
    Chen R et al. Hypoxia increases sirtuin 1 expression in a hypoxia-inducible factor-dependent manner. J. Biol. Chem. 2011 Apr;286(16):13869-78
    Chen R et al
    2011/01/01
  • 備考:
    Species: Human, Applications: WB, ChIP
  • 参照:
    PubMed
  • No.: 84
  • 文献情報:
    Adamski J et al. Hypoxia-induced cytotoxic drug resistance in osteosarcoma is independent of HIF-1Alpha. PLoS ONE 2013;8(6):e65304
    Adamski J et al
    2013/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 85
  • 文献情報:
    Husted RF et al. Oxygen regulation of the epithelial Na channel in the collecting duct. Am. J. Physiol. Renal Physiol. 2011 Feb;300(2):F412-24
    Husted RF et al
    2011/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 86
  • 文献情報:
    Toyoda H et al. Polycythemia and paraganglioma with a novel somatic HIF2A mutation in a male. Pediatrics 2014 Jun;133(6):e1787-91
    Toyoda H et al
    2014/01/01
  • 備考:
    Species: Human, Applications: IHC-P
  • 参照:
    PubMed
  • No.: 87
  • 文献情報:
    Vaapil M et al. Hypoxic conditions induce a cancer-like phenotype in human breast epithelial cells. PLoS ONE 2012;7(9):e46543
    Vaapil M et al
    2012/01/01
  • 備考:
    Species: Human, Applications: IHC, WB
  • 参照:
    PubMed
  • No.: 88
  • 文献情報:
    Zimmer M et al. Inhibition of hypoxia-inducible factor is sufficient for growth suppression of VHL-/- tumors. Mol. Cancer Res. 2004 Feb;2(2):89-95
    Zimmer M et al
    2004/01/01
  • 備考:
    Applications: WB
  • 参照:
    PubMed
  • No.: 89
  • 文献情報:
    Grabmaier K et al. Strict regulation of CAIX(G250/MN) by HIF-1alpha in clear cell renal cell carcinoma. Oncogene 2004 Jul;23(33):5624-31
    Grabmaier K et al
    2004/01/01
  • 備考:
    Species: Human
  • 参照:
    PubMed
  • No.: 90
  • 文献情報:
    Imamura T et al. HIF-1alpha and HIF-2alpha have divergent roles in colon cancer. Int. J. Cancer 2009 Feb;124(4):763-71
    Imamura T et al
    2009/01/01
  • 備考:
    Species: Human, Applications: IHC-P, WB
  • 参照:
    PubMed
  • No.: 91
  • 文献情報:
    Scheuermann TH et al. Allosteric inhibition of hypoxia inducible factor-2 with small molecules. Nat. Chem. Biol. 2013 Apr;9(4):271-6
    Scheuermann TH et al
    2013/01/01
  • 備考:
    Species: Human, Applications: ChIP
  • 参照:
    PubMed
  • No.: 92
  • 文献情報:
    Abbruzzetti S et al. Ligand migration through the internal hydrophobic cavities in human neuroglobin. Proc. Natl. Acad. Sci. U.S.A. 2009 Nov;106(45):18984-9
    Abbruzzetti S et al
    2009/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 93
  • 文献情報:
    Arvidsson Y et al. Hypoxia stimulates CXCR4 signalling in ileal carcinoids. Endocr. Relat. Cancer 2010 Jun;17(2):303-16
    Arvidsson Y et al
    2010/01/01
  • 備考:
    Species: Human, Applications: IHC
  • 参照:
    PubMed
  • No.: 94
  • 文献情報:
    Sutphin PD et al. Targeting the loss of the von Hippel-Lindau tumor suppressor gene in renal cell carcinoma cells. Cancer Res. 2007 Jun;67(12):5896-905
    Sutphin PD et al
    2007/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 95
  • 文献情報:
    Thomas S et al. CD24 Is an Effector of HIF-1-Driven Primary Tumor Growth and Metastasis. Cancer Res. 2012 Nov;72(21):5600-12
    Thomas S et al
    2012/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 96
  • 文献情報:
    Demachi-Okamura A et al. Autophagy Creates a CTL Epitope That Mimics Tumor-Associated Antigens. PLoS ONE 2012;7(10):e47126
    Demachi-Okamura A et al
    2012/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 97
  • 文献情報:
    Yeh IJ et al. HEXIM1 down-regulates hypoxia-inducible factor-1&#x3B1; protein stability. Biochem. J. 2013 Dec;456(2):195-204
    Yeh IJ et al
    2013/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 98
  • 文献情報:
    Havasi A et al. Histone acetyl transferase (HAT) HBO1 and JADE1 in epithelial cell regeneration. Am. J. Pathol. 2013 Jan;182(1):152-62
    Havasi A et al
    2013/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 99
  • 文献情報:
    Lin Q et al. Differential hypoxic regulation of hypoxia-inducible factors 1alpha and 2alpha. Mol. Cancer Res. 2011 Jun;9(6):757-65
    Lin Q et al
    2011/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 100
  • 文献情報:
    Macaulay IC et al. Canonical Wnt signaling in megakaryocytes regulates proplatelet formation. Blood 2013 Jan;121(1):188-96
    Macaulay IC et al
    2013/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 101
  • 文献情報:
    Zhang T et al. The contributions of HIF-target genes to tumor growth in RCC. PLoS ONE 2013;8(11):e80544
    Zhang T et al
    2013/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 102
  • 文献情報:
    Xu M et al. An acetate switch regulates stress erythropoiesis. Nat. Med. 2014 Sep;20(9):1018-26
    Xu M et al
    2014/01/01
  • 備考:
    Species: Human, Applications: WB, ChIP, IP
  • 参照:
    PubMed
  • No.: 103
  • 文献情報:
    Xia G et al. Positive expression of HIF-2alpha/EPAS1 in invasive bladder cancer. Urology 2002 May;59(5):774-8
    Xia G et al
    2002/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 104
  • 文献情報:
    Talks KL et al. The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages. Am. J. Pathol. 2000 Aug;157(2):411-21
    Talks KL et al
    2000/01/01
  • 備考:
    Applications: WB, IHC
  • 参照:
    PubMed
  • No.: 105
  • 文献情報:
    Blancher C et al. Relationship of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression to vascular endothelial growth factor induction and hypoxia survival in human breast cancer cell lines. Cancer Res. 2000 Dec;60(24):7106-13
    Blancher C et al
    2000/01/01
  • 備考:
    Applications: WB, IHC
  • 参照:
    PubMed