Anti-HIF-1β, Mouse-Mono(H1β234) <Anti-Hypoxia-Inducible Factor 1β>

データシート

• 商品コード：NB100-124
• メーカー：NOV
• 包装：100μl
• 価格： ¥103,000
• 在庫：無(未発注)

マイリストに追加 マイリストに追加済

• No.： 1
• 文献情報：
  Zagzag D et al. Expression of hypoxia-inducible factor 1alpha in brain tumors: association with angiogenesis, invasion, and progression. Cancer 2000 Jun;88(11):2606-18
  Zagzag D et al
  2000/01/01
  
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• No.： 2
• 文献情報：
  Tendler DS et al. Intersection of interferon and hypoxia signal transduction pathways in nitric oxide-induced tumor apoptosis. Cancer Res. 2001 May;61(9):3682-8
  Tendler DS et al
  2001/01/01
  
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• No.： 3
• 文献情報：
  Zhong H et al. Hypoxia-inducible factor 1alpha and 1beta proteins share common signaling pathways in human prostate cancer cells. Biochem. Biophys. Res. Commun. 2001 Jun;284(2):352-6
  Zhong H et al
  2001/01/01
  
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• No.： 4
• 文献情報：
  Mabjeesh NJ et al. Geldanamycin induces degradation of hypoxia-inducible factor 1alpha protein via the proteosome pathway in prostate cancer cells. Cancer Res. 2002 May;62(9):2478-82
  Mabjeesh NJ et al
  2002/01/01
  
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• No.： 5
• 文献情報：
  Bernaudin M et al. Brain genomic response following hypoxia and re-oxygenation in the neonatal rat. Identification of genes that might contribute to hypoxia-induced ischemic tolerance. J. Biol. Chem. 2002 Oct;277(42):39728-38
  Bernaudin M et al
  2002/01/01
  
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• No.： 6
• 文献情報：
  Fukuda R et al. Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells. J. Biol. Chem. 2002
  Fukuda R et al
  2002/01/01
  
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• No.： 7
• 文献情報：
  Rapisarda A et al. Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway. Cancer Res. 2002 Aug;62(15):4316-24
  Rapisarda A et al
  2002/01/01
  
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• No.： 8
• 文献情報：
  Volm M et al. Protein expression profiles indicative for drug resistance of non-small cell lung cancer. Br. J. Cancer 2002 Jul;87(3):251-7
  Volm M et al
  2002/01/01
  
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• No.： 9
• 文献情報：
  Elvert G et al. Cooperative interaction of hypoxia-inducible factor-2alpha (HIF-2alpha ) and Ets-1 in the transcriptional activation of vascular endothelial growth factor receptor-2 (Flk-1). J. Biol. Chem. 2003 Feb;278(9):7520-30
  Elvert G et al
  2003/01/01
  
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• No.： 10
• 文献情報：
  Mabjeesh NJ et al. Dibenzoylmethane, a natural dietary compound, induces HIF-1 alpha and increases expression of VEGF. Biochem. Biophys. Res. Commun. 2003 Mar;303(1):279-86
  Mabjeesh NJ et al
  2003/01/01
  
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• No.： 11
• 文献情報：
  Mabjeesh NJ et al. 2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF. Cancer Cell 2003 Apr;3(4):363-75
  Mabjeesh NJ et al
  2003/01/01
  
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• No.： 12
• 文献情報：
  Fukuda R et al. Vascular endothelial growth factor gene expression in colon cancer cells exposed to prostaglandin E2 is mediated by hypoxia-inducible factor 1. Cancer Res. 2003 May;63(9):2330-4
  Fukuda R et al
  2003/01/01
  
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• No.： 13
• 文献情報：
  Kasuno K et al. Nitric oxide induces hypoxia-inducible factor 1 activation that is dependent on MAPK and phosphatidylinositol 3-kinase signaling. J. Biol. Chem. 2004 Jan;279(4):2550-8
  Kasuno K et al
  2004/01/01
  
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• No.： 14
• 文献情報：
  Alam H et al. Follicle-stimulating hormone activation of hypoxia-inducible factor-1 by the phosphatidylinositol 3-kinase/AKT/Ras homolog enriched in brain (Rheb)/mammalian target of rapamycin (mTOR) pathway is necessary for induction of select protein mar
  Alam H et al
  2004/01/01
  
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• No.： 15
• 文献情報：
  Rapisarda A et al. Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: mechanism and therapeutic implications. Cancer Res. 2004 Feb;64(4):1475-82
  Rapisarda A et al
  2004/01/01
  
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• No.： 16
• 文献情報：
  Slomiany MG et al. Autocrine effects of IGF-I-induced VEGF and IGFBP-3 secretion in retinal pigment epithelial cell line ARPE-19. Am. J. Physiol., Cell Physiol. 2004 Sep;287(3):C746-53
  Slomiany MG et al
  2004/01/01
  
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• No.： 17
• 文献情報：
  Arsham AM et al. Akt and hypoxia-inducible factor-1 independently enhance tumor growth and angiogenesis. Cancer Res. 2004 May;64(10):3500-7
  Arsham AM et al
  2004/01/01
  
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• No.： 18
• 文献情報：
  Slomiany MG et al. IGF-1-induced VEGF and IGFBP-3 secretion correlates with increased HIF-1 alpha expression and activity in retinal pigment epithelial cell line D407. Invest. Ophthalmol. Vis. Sci. 2004 Aug;45(8):2838-47
  Slomiany MG et al
  2004/01/01
  
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• No.： 19
• 文献情報：
  Hirota K et al. Induction of hypoxia-inducible factor 1 activity by muscarinic acetylcholine receptor signaling. J. Biol. Chem. 2004 Oct;279(40):41521-8
  Hirota K et al
  2004/01/01
  
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• No.： 20
• 文献情報：
  Schultz K et al. Hypoxia and hypoxia-inducible factor-1alpha promote growth factor-induced proliferation of human vascular smooth muscle cells. Am. J. Physiol. Heart Circ. Physiol. 2006 Jun;290(6):H2528-34
  Schultz K et al
  2006/01/01
  
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• No.： 21
• 文献情報：
  Amir S et al. MSF-A interacts with hypoxia-inducible factor-1alpha and augments hypoxia-inducible factor transcriptional activation to affect tumorigenicity and angiogenesis. Cancer Res. 2006 Jan;66(2):856-66
  Amir S et al
  2006/01/01
  
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• No.： 22
• 文献情報：
  Oda T et al. Activation of hypoxia-inducible factor 1 during macrophage differentiation. Am. J. Physiol., Cell Physiol. 2006 Jul;291(1):C104-13
  Oda T et al
  2006/01/01
  
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• No.： 23
• 文献情報：
  Hui AS et al. Calcium signaling stimulates translation of HIF-alpha during hypoxia. FASEB J. 2006 Mar;20(3):466-75
  Hui AS et al
  2006/01/01
  
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• No.： 24
• 文献情報：
  Okuyama H et al. Expression of vascular endothelial growth factor receptor 1 in bone marrow-derived mesenchymal cells is dependent on hypoxia-inducible factor 1. J. Biol. Chem. 2006 Jun;281(22):15554-63
  Okuyama H et al
  2006/01/01
  
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• No.： 25
• 文献情報：
  Hu CJ et al. Differential regulation of the transcriptional activities of hypoxia-inducible factor 1 alpha (HIF-1alpha) and HIF-2alpha in stem cells. Mol. Cell. Biol. 2006 May;26(9):3514-26
  Hu CJ et al
  2006/01/01
  
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• No.： 26
• 文献情報：
  Nakamura K et al. Brain-derived neurotrophic factor activation of TrkB induces vascular endothelial growth factor expression via hypoxia-inducible factor-1alpha in neuroblastoma cells. Cancer Res. 2006 Apr;66(8):4249-55
  Nakamura K et al
  2006/01/01
  
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• No.： 27
• 文献情報：
  Slomiany MG et al. Hypoxia-inducible factor-1-dependent and -independent regulation of insulin-like growth factor-1-stimulated vascular endothelial growth factor secretion. J. Pharmacol. Exp. Ther. 2006 Aug;318(2):666-75
  Slomiany MG et al
  2006/01/01
  
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• No.： 28
• 文献情報：
  Asikainen TM et al. Improved lung growth and function through hypoxia-inducible factor in primate chronic lung disease of prematurity. FASEB J. 2006 Aug;20(10):1698-700
  Asikainen TM et al
  2006/01/01
  
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• No.： 29
• 文献情報：
  Baek JH et al. Spermidine/spermine-N1-acetyltransferase 2 is an essential component of the ubiquitin ligase complex that regulates hypoxia-inducible factor 1alpha. J. Biol. Chem. 2007 Aug;282(32):23572-80
  Baek JH et al
  2007/01/01
  
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• No.： 30
• 文献情報：
  Cheng G et al. Involvement of chloride channels in TGF-beta1-induced apoptosis of human bronchial epithelial cells. Am. J. Physiol. Lung Cell Mol. Physiol. 2007 Nov;293(5):L1339-47
  Cheng G et al
  2007/01/01
  
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• No.： 31
• 文献情報：
  Baek JH et al. Spermidine/spermine N(1)-acetyltransferase-1 binds to hypoxia-inducible factor-1alpha (HIF-1alpha) and RACK1 and promotes ubiquitination and degradation of HIF-1alpha. J. Biol. Chem. 2007 Nov;282(46):33358-66
  Baek JH et al
  2007/01/01
  
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• No.： 32
• 文献情報：
  Engebretsen BJ et al. Acute hypobaric hypoxia (5486 m) induces greater pulmonary HIF-1 activation in hilltop compared to madison rats. High Alt. Med. Biol. 2007;8(4):312-21
  Engebretsen BJ et al
  2007/01/01
  
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• No.： 33
• 文献情報：
  Amir S et al. SEPT9_v1 up-regulates hypoxia-inducible factor 1 by preventing its RACK1-mediated degradation. J. Biol. Chem. 2009 Apr;284(17):11142-51
  Amir S et al
  2009/01/01
  
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• No.： 34
• 文献情報：
  Aminova LR et al. Antioxidants, HIF prolyl hydroxylase inhibitors or short interfering RNAs to BNIP3 or PUMA, can prevent prodeath effects of the transcriptional activator, HIF-1alpha, in a mouse hippocampal neuronal line. Antioxid. Redox Signal. 2008 Dec
  Aminova LR et al
  2008/01/01
  
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• No.： 35
• 文献情報：
  Peng YJ et al. Hypoxia-inducible factor 2&#x3B1; (HIF-2&#x3B1;) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension. Proc. Natl. Acad. Sci. U.S.A. 2011 Feb;108(7):3065-70
  Peng YJ et al
  2011/01/01
  
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• No.： 36
• 文献情報：
  Puppo M et al. Topotecan inhibits vascular endothelial growth factor production and angiogenic activity induced by hypoxia in human neuroblastoma by targeting hypoxia-inducible factor-1alpha and -2alpha. Mol. Cancer Ther. 2008 Jul;7(7):1974-84
  Puppo M et al
  2008/01/01
  
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• No.： 37
• 文献情報：
  Lauzier MC et al. (2R)-[(4-Biphenylylsulfonyl)amino]-N-hydroxy-3-phenylpropionamide (BiPS), a matrix metalloprotease inhibitor, is a novel and potent activator of hypoxia-inducible factors. Mol. Pharmacol. 2008 Jul;74(1):282-8
  Lauzier MC et al
  2008/01/01
  
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• No.： 38
• 文献情報：
  Lysiak JJ et al. Hypoxia-inducible factor-1alpha is constitutively expressed in murine Leydig cells and regulates 3beta-hydroxysteroid dehydrogenase type 1 promoter activity. J. Androl. ;30(2):146-56
  Lysiak JJ et al
  
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• No.： 39
• 文献情報：
  Tissot van Patot MC et al. Greater vascularity, lowered HIF-1/DNA binding, and elevated GSH as markers of adaptation to in vivo chronic hypoxia. Am. J. Physiol. Lung Cell Mol. Physiol. 2004 Sep;287(3):L525-32
  Tissot van Patot MC et al
  2004/01/01
  
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• No.： 40
• 文献情報：
  Kransler KM et al. Lung development in the Holtzman rat is adversely affected by gestational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol. Sci. 2009 Feb;107(2):498-511
  Kransler KM et al
  2009/01/01
  
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• No.： 41
• 文献情報：
  Zhou L et al. The von Hippel-Lindau tumor suppressor protein promotes c-Cbl-independent poly-ubiquitylation and degradation of the activated EGFR. PLoS ONE 2011;6(9):e23936
  Zhou L et al
  2011/01/01
  
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• No.： 42
• 文献情報：
  Lunde IG et al. Hypoxia inducible factor 1 links fast-patterned muscle activity and fast muscle phenotype in rats. J. Physiol. (Lond.) 2011 Mar;589(Pt 6):1443-54
  Lunde IG et al
  2011/01/01
  
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• No.： 43
• 文献情報：
  Zhang H et al. HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity. Cancer Cell 2007 May;11(5):407-20
  Zhang H et al
  2007/01/01
  
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• No.： 44
• 文献情報：
  Lin Q et al. Differential hypoxic regulation of hypoxia-inducible factors 1alpha and 2alpha. Mol. Cancer Res. 2011 Jun;9(6):757-65
  Lin Q et al
  2011/01/01
  
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• No.： 45
• 文献情報：
  Luo W et al. Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1. Cell 2011 May;145(5):732-44
  Luo W et al
  2011/01/01
  
• 備考：
  Applications: ChIP, Species: Human
• 参照：
  

• No.： 46
• 文献情報：
  Kaira K et al. Depolarized MUC1 expression is closely associated with hypoxic markers and poor outcome in resected non-small cell lung cancer. Int. J. Surg. Pathol. 2012 Jun;20(3):223-32
  Kaira K et al
  2012/01/01
  
• 備考：
  Applications: IHC, Species: Human
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• No.： 47
• 文献情報：
  Uniacke J et al. An oxygen-regulated switch in the protein synthesis machinery. Nature 2012 Jun;486(7401):126-9
  Uniacke J et al
  2012/01/01
  
• 備考：
  Applications: WB, Species: Human
• 参照：
  

• No.： 48
• 文献情報：
  Singh AK et al. Intracellular pathogen Leishmania donovani activates hypoxia inducible factor-1 by dual mechanism for survival advantage within macrophage. PLoS ONE 2012;7(6):e38489
  Singh AK et al
  2012/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 49
• 文献情報：
  Chiabrando D et al. Cell-specific regulation of Ferroportin transcription following experimentally-induced acute anemia in mice. Blood Cells Mol. Dis. 2012 Aug;
  Chiabrando D et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: WB, IP
• 参照：
  

• No.： 50
• 文献情報：
  Wong CC et al. Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation. Proc. Natl. Acad. Sci. U.S.A. 2011 Sep;108(39):16369-74
  Wong CC et al
  2011/01/01
  
• 備考：
  Species: Human, Applications: WB
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• No.： 51
• 文献情報：
  Krishnamachary B et al. Hypoxia Regulates CD44 and Its Variant Isoforms through HIF-1&#x3B1; in Triple Negative Breast Cancer. PLoS ONE 2012;7(8):e44078
  Krishnamachary B et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: WB
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• No.： 52
• 文献情報：
  Zhang D et al. The Requirement of c-Jun N-terminal Kinase 2 in Regulation of Hypoxia-inducing Factor-1&#x3B1; mRNA Stability. J. Biol. Chem. 2012 Oct;287(41):34361-71
  Zhang D et al
  2012/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 53
• 文献情報：
  Zhong, H., et al. Hypoxia-inducible Factor 1 as a novel diagnostic therapeutic target in human Cancers. Recent Res. Devel. Cancer. 3: 49-68. 2001.
  
  
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• No.： 54
• 文献情報：
  Pawlus MR et al. Upstream Stimulatory Factor 2 and Hypoxia-Inducible Factor 2&#x3B1; (HIF2&#x3B1;) Cooperatively Activate HIF2 Target Genes during Hypoxia. Mol. Cell. Biol. 2012 Nov;32(22):4595-610
  Pawlus MR et al
  2012/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 55
• 文献情報：
  Luo W et al. Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression. Proc. Natl. Acad. Sci. U.S.A. 2012 Dec;109(49):E3367-76
  Luo W et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ChIP
• 参照：
  

• No.： 56
• 文献情報：
  Storti P et al. Hypoxia-inducible factor (HIF)-1&#x3B1; suppression in myeloma cells blocks tumoral growth in vivo inhibiting angiogenesis and bone destruction. Leukemia 2013 Jan;
  Storti P et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 57
• 文献情報：
  Chaturvedi P et al. Hypoxia-inducible factor-dependent breast cancer-mesenchymal stem cell bidirectional signaling promotes metastasis. J. Clin. Invest. 2013 Jan;123(1):189-205
  Chaturvedi P et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: ChIP
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• No.： 58
• 文献情報：
  Tamama K et al. Differential roles of hypoxia inducible factor subunits in multipotential stromal cells under hypoxic condition. J. Cell. Biochem. 2011 Mar;112(3):804-17
  Tamama K et al
  2011/01/01
  
• 備考：
  Species: Human, Applications: WB, IHC
• 参照：
  

• No.： 59
• 文献情報：
  Yuan G et al. Mutual antagonism between hypoxia-inducible factors 1&#x3B1; and 2&#x3B1; regulates oxygen sensing and cardio-respiratory homeostasis. Proc. Natl. Acad. Sci. U.S.A. 2013 May;110(19):E1788-96
  Yuan G et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 60
• 文献情報：
  Balamurugan K et al. FBXW7&#x3B1; attenuates inflammatory signalling by downregulating C/EBP&#x3B4; and its target gene Tlr4. Nat Commun 2013;4:1662
  Balamurugan K et al
  2013/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 61
• 文献情報：
  Pawlus MR et al. STAT3 and HIF1&#x3B1; cooperatively activate HIF1 target genes in MDA-MB-231 and RCC4 cells. Oncogene 2013 Apr;
  Pawlus MR et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 62
• 文献情報：
  Zhong, H et al. Hypoxia-inducible Factor 1 as a novel diagnostic therapeutic target in human Cancers. Recent Res. Devel. Cancer. 3: 49-68. 2001
  
  
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• 参照：
  

• No.： 63
• 文献情報：
  Sena JA et al. BRG1 and BRM Chromatin-Remodeling Complexes Regulate the Hypoxia Response by Acting as Coactivators for a Subset of Hypoxia-Inducible Transcription Factor Target Genes. Mol. Cell. Biol. 2013 Oct;33(19):3849-63
  Sena JA et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: WB, ChIP
• 参照：
  

• No.： 64
• 文献情報：
  Shimojo N et al. Contributory role of VEGF overexpression in endothelin-1-induced cardiomyocyte hypertrophy. Am. J. Physiol. Heart Circ. Physiol. 2007 Jul;293(1):H474-81
  Shimojo N et al
  2007/01/01
  
• 備考：
  Species: Rat, Applications: WB
• 参照：
  

• No.： 65
• 文献情報：
  Hu CJ et al. The N-terminal transactivation domain confers target gene specificity of hypoxia-inducible factors HIF-1alpha and HIF-2alpha. Mol. Biol. Cell 2007 Nov;18(11):4528-42
  Hu CJ et al
  2007/01/01
  
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• No.： 66
• 文献情報：
  Cai Z et al. Hypoxia-inducible factor 1 is required for remote ischemic preconditioning of the heart. Proc. Natl. Acad. Sci. U.S.A. 2013 Oct;110(43):17462-7
  Cai Z et al
  2013/01/01
  
• 備考：
  Applications: ChIP, WB
• 参照：
  

• No.： 67
• 文献情報：
  Xiang L et al. Ganetespib blocks HIF-1 activity and inhibits tumor growth, vascularization, stem cell maintenance, invasion, and metastasis in orthotopic mouse models of triple-negative breast cancer. J. Mol. Med. 2013 Nov;
  Xiang L et al
  2013/01/01
  
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• No.： 68
• 文献情報：
  Suzuki K et al. Differential roles of prostaglandin E-type receptors in activation of hypoxia-inducible factor 1 by prostaglandin E1 in vascular-derived cells under non-hypoxic conditions. PeerJ 2013;1:e220
  Suzuki K et al
  2013/01/01
  
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• No.： 69
• 文献情報：
  Gilkes DM et al. Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells. Proc. Natl. Acad. Sci. U.S.A. 2014 Jan;111(3):E384-93
  Gilkes DM et al
  2014/01/01
  
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• No.： 70
• 文献情報：
  Takano N et al. Hypoxia-inducible factors regulate human and rat cystathionine &#x3B2;-synthase gene expression. Biochem. J. 2014 Mar;458(2):203-11
  Takano N et al
  2014/01/01
  
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• No.： 71
• 文献情報：
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  Zhang J et al. Nerve growth factor regulates the expression of vascular endothelial growth factor in human HaCaT keratinocytes via PI3K/mTOR pathway. Genet. Mol. Res. 2014;13(4):9324-35
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