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在庫・価格 : 2024年05月01日 09時10分 現在

商品名 商品コード メーカー 包装 価格 在庫 リスト
Anti-HIF-1α, Mouse-Mono(H1alpha67) <Anti-Hypoxia-Inducible Factor 1α>
データシート
NB100-123 NOVノバス バイオロジカルス
Novus biologicals, LLC
100 μl ¥103,000
(未発注)
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在庫・価格 : 2024年05月01日 09時10分 現在

Anti-HIF-1α, Mouse-Mono(H1alpha67) <Anti-Hypoxia-Inducible Factor 1α>

  • 商品コード:NB100-123
  • メーカー:NOV
  • 包装:100μl
  • 価格: ¥103,000
  • 在庫:無(未発注)
使用文献
No. 文献情報 備考 参照
1 Zhong H et al. Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases. Cancer Res. 1999 Nov;59(22):5830-5
Zhong H et al
1999/01/01
Immunohistochemistry-paraffin, mouse/human PubMed
2 Tacchini L et al. Hepatocyte growth factor signalling stimulates hypoxia inducible factor-1 (HIF-1) activity in HepG2 hepatoma cells. Carcinogenesis 2001 Sep;22(9):1363-71
Tacchini L et al
2001/01/01
PubMed
3 Duyndam MC et al. Induction of vascular endothelial growth factor expression and hypoxia-inducible factor 1alpha protein by the oxidative stressor arsenite. J. Biol. Chem. 2001 Dec;276(51):48066-76
Duyndam MC et al
2001/01/01
Western blot, human PubMed
4 Tang T et al. Phosphorylation by mitogen-activated protein kinase mediates the hypoxia-induced turnover of the TAL1/SCL transcription factor in endothelial cells. J. Biol. Chem. 2002 May;277(21):18365-72
Tang T et al
2002/01/01
Western blot, human PubMed
5 Fujii T et al. Effect of hypoxia on human seminoma cells. Int. J. Oncol. 2002 May;20(5):955-62
Fujii T et al
2002/01/01
Immunocytochemistry, human PubMed
6 Mandriota SJ et al. HIF activation identifies early lesions in VHL kidneys: evidence for site-specific tumor suppressor function in the nephron. Cancer Cell 2002 Jun;1(5):459-68
Mandriota SJ et al
2002/01/01
Immunohistochemistry, human PubMed
7 Burke B et al. Hypoxia-induced gene expression in human macrophages: implications for ischemic tissues and hypoxia-regulated gene therapy. Am. J. Pathol. 2003 Oct;163(4):1233-43
Burke B et al
2003/01/01
Immunohistochemistry, human PubMed
8 de Candia P et al. Angiogenesis impairment in Id-deficient mice cooperates with an Hsp90 inhibitor to completely suppress HER2/neu-dependent breast tumors. Proc. Natl. Acad. Sci. U.S.A. 2003 Oct;100(21):12337-42
de Candia P et al
2003/01/01
Immunohistochemistry-paraffin, mouse PubMed
9 Lu H et al. Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1. J. Biol. Chem. 2005 Dec;280(51):41928-39
Lu H et al
2005/01/01
PubMed
10 Laderoute KR et al. 5&quot;-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments. Mol. Cell. Biol. 2006 Jul;26(14):5336-47
Laderoute KR et al
2006/01/01
PubMed
11 An HJ et al. Activation of Ras up-regulates pro-apoptotic BNIP3 in nitric oxide-induced cell death. J. Biol. Chem. 2006 Nov;281(45):33939-48
An HJ et al
2006/01/01
PubMed
12 Khan Z et al. Peroxisomal localization of hypoxia-inducible factors and hypoxia-inducible factor regulatory hydroxylases in primary rat hepatocytes exposed to hypoxia-reoxygenation. Am. J. Pathol. 2006 Oct;169(4):1251-69
Khan Z et al
2006/01/01
PubMed
13 Ramanathan M et al. Synergistic up-regulation of vascular endothelial growth factor (VEGF) expression in macrophages by adenosine A2A receptor agonists and endotoxin involves transcriptional regulation via the hypoxia response element in the VEGF promoter
Ramanathan M et al
2007/01/01
PubMed
14 Tracy K et al. BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy. Mol. Cell. Biol. 2007 Sep;27(17):6229-42
Tracy K et al
2007/01/01
PubMed
15 Klatte T et al. Hypoxia-inducible factor 1 alpha in clear cell renal cell carcinoma. Clin. Cancer Res. 2007 Dec;13(24):7388-93
Klatte T et al
2007/01/01
PubMed
16 Lee DW et al. Inhibition of prolyl hydroxylase protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity: model for the potential involvement of the hypoxia-inducible factor pathway in Parkinson disease. J. Biol. Chem. 2009 Oct;2
Lee DW et al
2009/01/01
PubMed
17 Franco M et al. Targeted anti-vascular endothelial growth factor receptor-2 therapy leads to short-term and long-term impairment of vascular function and increase in tumor hypoxia. Cancer Res. 2006 Apr;66(7):3639-48
Franco M et al
2006/01/01
PubMed
18 Singh M et al. Matrix metalloproteinases and their inhibitors and inducer in gestational trophoblastic diseases and normal placenta. Gynecol. Oncol. 2011 Jul;122(1):178-82
Singh M et al
2011/01/01
PubMed
19 Rosenberger C et al. Activation of hypoxia-inducible factors ameliorates hypoxic distal tubular injury in the isolated perfused rat kidney. Nephrol. Dial. Transplant. 2008 Nov;23(11):3472-8
Rosenberger C et al
2008/01/01
PubMed
20 Kaira K et al. Relationship between 18F-FDG uptake on positron emission tomography and molecular biology in malignant pleural mesothelioma. Eur. J. Cancer 2012 May;48(8):1244-54
Kaira K et al
2012/01/01
PubMed
21 H旦lscher M et al. Unfavourable consequences of chronic cardiac HIF-1&#x3B1; stabilization. Cardiovasc. Res. 2012 Apr;94(1):77-86
H旦lscher M et al
2012/01/01
PubMed
22 Stagg J et al. Antibodies targeted to TRAIL receptor-2 and ErbB-2 synergize in vivo and induce an antitumor immune response. Proc. Natl. Acad. Sci. U.S.A. 2008 Oct;105(42):16254-9
Stagg J et al
2008/01/01
PubMed
23 Gibbings S et al. Xanthine oxidoreductase promotes the inflammatory state of mononuclear phagocytes through effects on chemokine expression, peroxisome proliferator-activated receptor-{gamma} sumoylation, and HIF-1{alpha}. J. Biol. Chem. 2011 Jan;286(2):9
Gibbings S et al
2011/01/01
PubMed
24 Yamamoto Y et al. Hypoxia-inducible factor 1alpha is closely linked to an aggressive phenotype in breast cancer. Breast Cancer Res. Treat. 2008 Aug;110(3):465-75
Yamamoto Y et al
2008/01/01
PubMed
25 . RETRACTED ARTICLE: Relationship between (18)F-FDG uptake on PET and various biologic molecular markers in benign pulmonary lesion: comparison with primary lung cancer. Ann Nucl Med 2012 Apr;26(3):288

2012/01/01
PubMed
26 Weroha SJ et al. Phase II trial of lapatinib and topotecan (LapTop) in patients with platinum-refractory/resistant ovarian and primary peritoneal carcinoma. Gynecol. Oncol. 2011 Jul;122(1):116-20
Weroha SJ et al
2011/01/01
PubMed
27 Rhoads RP et al. Satellite cell-mediated angiogenesis in vitro coincides with a functional hypoxia-inducible factor pathway. Am. J. Physiol., Cell Physiol. 2009 Jun;296(6):C1321-8
Rhoads RP et al
2009/01/01
PubMed
28 Aubert S et al. MUC1, a new hypoxia inducible factor target gene, is an actor in clear renal cell carcinoma tumor progression. Cancer Res. 2009 Jul;69(14):5707-15
Aubert S et al
2009/01/01
PubMed
29 Radek KA et al. Acute ethanol exposure disrupts VEGF receptor cell signaling in endothelial cells. Am. J. Physiol. Heart Circ. Physiol. 2008 Jul;295(1):H174-84
Radek KA et al
2008/01/01
PubMed
30 H旦lscher M et al. Cardiomyocyte-specific prolyl-4-hydroxylase domain 2 knock out protects from acute myocardial ischemic injury. J. Biol. Chem. 2011 Apr;286(13):11185-94
H旦lscher M et al
2011/01/01
PubMed
31 Sreekumar PG et al. Methionine sulfoxide reductase A: Structure, function and role in ocular pathology. World J Biol Chem 2011 Aug;2(8):184-92
Sreekumar PG et al
2011/01/01
PubMed
32 Hatipoglu OF et al. ADAMTS1 is a unique hypoxic early response gene expressed by endothelial cells. J. Biol. Chem. 2009 Jun;284(24):16325-33
Hatipoglu OF et al
2009/01/01
PubMed
33 Kaira K et al. (18)F-FDG uptake on PET in primary mediastinal non-thymic neoplasm: A clinicopathological study. Eur J Radiol 2011 Nov;
Kaira K et al
2011/01/01
PubMed
34 Schneider C et al. Systemic hypoxia differentially affects neurogenesis during early mouse brain maturation. Brain Dev. 2012 Apr;34(4):261-73
Schneider C et al
2012/01/01
PubMed
35 Kaira K et al. Correlation between 18F-FDG uptake on PET and molecular biology in metastatic pulmonary tumors. J. Nucl. Med. 2011 May;52(5):705-11
Kaira K et al
2011/01/01
PubMed
36 Hsu K et al. Miltenberger blood group antigen type III (Mi.III) enhances the expression of band 3. Blood 2009 Aug;114(9):1919-28
Hsu K et al
2009/01/01
PubMed
37 Huang LJ et al. Hypoxia-inducible factor 1&#x3B1; regulates the expression of the mitochondrial ATPase inhibitor protein (IF1) in rat liver. Shock 2011 Jul;36(1):90-6
Huang LJ et al
2011/01/01
Applications: WB, Species: Rat PubMed
38 Park HJ et al. Hypoxia inducible factor-1&#x3B1; directly induces the expression of receptor activator of nuclear factor-&#x3BA;B ligand in periodontal ligament fibroblasts. Mol. Cells 2011 Jun;31(6):573-8
Park HJ et al
2011/01/01
Applications: WB, Species: Human PubMed
39 Peurala E et al. Expressions of individual PHDs associate with good prognostic factors and increased proliferation in breast cancer patients. Breast Cancer Res. Treat. 2012 May;133(1):179-88
Peurala E et al
2012/01/01
Applications: IHC, Species: Human PubMed
40 Kaira K et al. Thymidylate synthase expression is closely associated with outcome in patients with pulmonary adenocarcinoma. Med. Oncol. 2011 Sep;
Kaira K et al
2011/01/01
Applications: IHC, Species: Human PubMed
41 Kaira K et al. MUC1 expression in pulmonary metastatic tumors: a comparison of primary lung cancer. Pathol. Oncol. Res. 2012 Apr;18(2):439-47
Kaira K et al
2012/01/01
Applications: IHC, Species: Human PubMed
42 Chu W et al. Mild hypoxia induced cardiomyocyte hypertrophy via up-regulation of HIF-1&#x3B1;-mediated TRPC signaling. J. Cell. Mol. Med. 2011 Nov;
Chu W et al
2011/01/01
Applications: ICC, IF, WB, Species: Rat PubMed
43 Jeong CW et al. The Role of Hypoxia-Inducible Factor-1&#x3B1; and -2&#x3B1; in Androgen Insensitive Prostate Cancer Cells. Urol Oncol 2012 Apr;
Jeong CW et al
2012/01/01
Applications: WB, Species: Human PubMed
44 Weber DC et al. The prognostic value of expression of HIF1&#x3B1;, EGFR and VEGF-A, in localized prostate cancer for intermediate- and high-risk patients treated with radiation therapy with or without androgen deprivation therapy. Radiat Oncol 2012;7:66
Weber DC et al
2012/01/01
Species: Human, Applications: IHC PubMed
45 Mhawech-Fauceglia P et al. The role of hypoxic-inducible factor (HIF1&#x3B1;) and aldolaseC protein in endometrial carcinogenesis: a retrospective study of 279 patients. BMJ Open 2012;2(4)
Mhawech-Fauceglia P et al
2012/01/01
Species: Human, Applications: IHC PubMed
46 Pang X, Wang Z, Yin D, Zhang Z. Overexpression of hypoxia-inducible factor prolyl- hydoxylase attenuated by HCG-induced vascular endothelial growth factor expression in luteal cells. African Journal of Biotechnology 10(42):8227-8235.

PubMed
47 Jiang W et al. Identification of a molecular signature underlying inhibition of mammary carcinoma growth by dietary N-3 fatty acids. Cancer Res. 2012 Aug;72(15):3795-806
Jiang W et al
2012/01/01
Species: Rat, Applications: WB PubMed
48 Kishimoto K et al. Hypoxia-induced up-regulation of angiogenin, besides VEGF, is related to progression of oral cancer. Oral Oncol 2012 Jun;
Kishimoto K et al
2012/01/01
Species: Human, Applications: WB, IHC PubMed
49 Kaira K, Oriuchi N, Takahashi T, et al. LAT1 expression is closely associated with hypoxic markers and mTOR in resected non-small cell lung cancer. Am J Translational Res;3(5):468-478. 2010.

PubMed
50 Chiavarina B et al. Metabolic reprogramming and two-compartment tumor metabolism: opposing role(s) of HIF1&#x3B1; and HIF2&#x3B1; in tumor-associated fibroblasts and human breast cancer cells. Cell Cycle 2012 Sep;11(17):3280-9
Chiavarina B et al
2012/01/01
Applications: WB, ICC/IF PubMed
51 Ding A et al. Chronic treatment with tempol does not significantly ameliorate renal tissue hypoxia or disease progression in a rodent model of polycystic kidney disease. Clin. Exp. Pharmacol. Physiol. 2012 Nov;39(11):917-29
Ding A et al
2012/01/01
Applications: IHC, ICC/IF PubMed
52 Galzio R et al. Hypoxia modulation of peroxisome proliferator-activated receptors (PPARs) in human glioblastoma stem cells. Implications for therapy. J. Cell. Biochem. 2012 Nov;113(11):3342-52
Galzio R et al
2012/01/01
Applications: FLOW, ICC/IF PubMed
53 Clarke DN et al. Perlecan Domain V Induces VEGf Secretion in Brain Endothelial Cells through Integrin &#x3B1;(5)&#x3B2;(1) and ERK-Dependent Signaling Pathways. PLoS ONE 2012;7(9):e45257
Clarke DN et al
2012/01/01
Applications: WB PubMed
54 Zhao Y et al. Targeting Cullin-RING ligases by MLN4924 induces autophagy via modulating the HIF1-REDD1-TSC1-mTORC1-DEPTOR axis. Cell Death Dis 2012;3:e386
Zhao Y et al
2012/01/01
Applications: WB PubMed
55 Ioannou M et al. Upregulation of VEGF expression is associated with accumulation of HIF-1&#x3B1; in the skin of na&#xEF;ve scleroderma patients. Mod Rheumatol 2012 Oct;
Ioannou M et al
2012/01/01
Species: Human, Applications: IHC PubMed
56 Shinmei S et al. MicroRNA-155 is a predictive marker for survival in patients with clear cell renal cell carcinoma. Int. J. Urol. 2012 Oct;
Shinmei S et al
2012/01/01
Species: Human, Applications: IHC PubMed
57 Kaira K et al. Biologic correlates of &#xB9;&#x2078;F-FDG uptake on PET in pulmonary pleomorphic carcinoma. Lung Cancer 2011 Feb;71(2):144-50
Kaira K et al
2011/01/01
Species: Human, Applications: IHC PubMed
58 Brenner RM et al. Molecular and functional aspects of menstruation in the macaque. Rev Endocr Metab Disord 2012 Oct;
Brenner RM et al
2012/01/01
Species: Avian, Applications: IHC PubMed
59 Lundgrin EL et al. Fasting 2-Deoxy-2-[18F]fluoro-D-glucose Positron Emission Tomography to Detect Metabolic Changes in Pulmonary Arterial Hypertension Hearts over 1 Year. Ann Am Thorac Soc 2013 Feb;10(1):1-9
Lundgrin EL et al
2013/01/01
Species: Human, Applications: IHC-P PubMed
60 Chaux A et al. Immunoexpression status and prognostic value of mammalian target of rapamycin and hypoxia-induced pathway members in papillary cell renal cell carcinomas. Hum. Pathol. 2012 Dec;43(12):2129-37
Chaux A et al
2012/01/01
Species: Human, Applications: IHC PubMed
61 Kaira K et al. Biologic correlation of 2-[18F]-fluoro-2-deoxy-D-glucose uptake on positron emission tomography in thymic epithelial tumors. J. Clin. Oncol. 2010 Aug;28(23):3746-53
Kaira K et al
2010/01/01
Species: Human, Applications: IHC PubMed
62 Gu HF et al. Impact of the hypoxia-inducible factor-1 &#x3B1; (HIF1A) Pro582Ser polymorphism on diabetes nephropathy. Diabetes Care 2013 Feb;36(2):415-21
Gu HF et al
2013/01/01
Species: Mouse, Applications: IHC-P PubMed
63 Reddy VD et al. Alcohol-induced oxidative/nitrosative stress alters brain mitochondrial membrane properties. Mol. Cell. Biochem. 2013 Mar;375(1-2):39-47
Reddy VD et al
2013/01/01
Species: Rat, Applications: WB PubMed
64 Aziz SA et al. Expression of drug targets in primary and matched metastatic renal cell carcinoma tumors. BMC Clin Pathol 2013;13(1):3
Aziz SA et al
2013/01/01
Species: Human, Applications: IHC PubMed
65 G旦ssl M et al. Low vasa vasorum densities correlate with inflammation and subintimal thickening: potential role in location--determination of atherogenesis. Atherosclerosis 2009 Oct;206(2):362-8
G旦ssl M et al
2009/01/01
Species: Porcine, Applications: IHC PubMed
66 Toba H et al. 18F-fluorodeoxyglucose positron emission tomography/computed tomography and the relationship between fluorodeoxyglucose uptake and the expression of hypoxia-inducible factor-1&#x3B1;, glucose transporter-1 and vascular endothelial growth fac
Toba H et al
2013/01/01
Species: Human, Applications: IHC-P PubMed
67 Flynn JR et al. Hypoxia-regulated protein expression, patient characteristics, and preoperative imaging as predictors of survival in adults with glioblastoma multiforme. Cancer 2008 Sep;113(5):1032-42
Flynn JR et al
2008/01/01
Species: Human, Applications: IHC-P PubMed
68 Kar AN et al. Intra-axonal synthesis of eukaryotic translation initiation factors regulates local protein synthesis and axon growth in rat sympathetic neurons. J. Neurosci. 2013 Apr;33(17):7165-74
Kar AN et al
2013/01/01
Species: Rat, Applications: WB PubMed
69 Evenou F et al. Gas-permeable membranes and co-culture with fibroblasts enable high-density hepatocyte culture as multilayered liver tissues. Biotechnol. Prog. 2011 Jul;27(4):1146-53
Evenou F et al
2011/01/01
Species: Mouse, Applications: IHC-P, ICC/IF PubMed
70 Kaira K, Oriuchi N, Takahashi T et al. LAT1 expression is closely associated with hypoxic markers and mTOR in resected non-small cell lung cancer. Am J Translational Res;3(5):468-478. 2010

PubMed
71 Tanaka T et al. Indoxyl sulfate signals for rapid mRNA stabilization of Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2 (CITED2) and suppresses the expression of hypoxia-inducible genes in experimental CKD and uremia. FASEB
Tanaka T et al
2013/01/01
Species: Human, Applications: WB, ChIP PubMed
72 Sceneay J et al. The antioxidant N-acetylcysteine prevents HIF-1 stabilization under hypoxia in vitro but does not affect tumorigenesis in multiple breast cancer models in vivo. PLoS ONE 2013;8(6):e66388
Sceneay J et al
2013/01/01
Species: Mouse, Applications: WB, ICC/IF PubMed
73 Salem AF et al. Downregulation of stromal BRCA1 drives breast cancer tumor growth via upregulation of HIF-1&#x3B1;, autophagy and ketone body production. Cell Cycle 2012 Nov;11(22):4167-73
Salem AF et al
2012/01/01
Species: Human, Applications: WB PubMed
74 Namas RA et al. Hypoxia-induced overexpression of BNIP3 is not dependent on hypoxia-inducible factor 1&#x3B1; in mouse hepatocytes. Shock 2011 Aug;36(2):196-202
Namas RA et al
2011/01/01
Species: Mouse, Applications: WB PubMed
75 Li J et al. Alpha-calcitonin gene-related peptide is protective against pressure overload-induced heart failure. Regul. Pept. 2013 Jun;185C:20-28
Li J et al
2013/01/01
Species: Mouse, Applications: WB PubMed
76 Li C et al. The mechanisms of chansu in inducing efficient apoptosis in colon cancer cells. Evid Based Complement Alternat Med 2013;2013:849054
Li C et al
2013/01/01
Species: Human, Applications: ICC/IF PubMed
77 Diensthuber M et al. Expression of bcl-2 is associated with microvessel density in olfactory neuroblastoma. J. Neurooncol. 2008 Sep;89(2):131-9
Diensthuber M et al
2008/01/01
Applications: IHC-P PubMed
78 Tezel G et al. Hypoxia-inducible factor 1alpha in the glaucomatous retina and optic nerve head. Arch. Ophthalmol. 2004 Sep;122(9):1348-56
Tezel G et al
2004/01/01
Species: Human, Applications: IHC-P PubMed
79 Anderson KM et al. The proliferative response of hela cells to 2-deoxy-D-glucose under hypoxic or anoxic conditions: an analogue for studying some properties of in vivo solid cancers. Anticancer Res. ;26(6B):4155-62
Anderson KM et al
Species: Human, Applications: IHC, WB PubMed
80 Zheng X et al. Cell-type-specific regulation of degradation of hypoxia-inducible factor 1 alpha: role of subcellular compartmentalization. Mol. Cell. Biol. 2006 Jun;26(12):4628-41
Zheng X et al
2006/01/01
Species: Rabbit, Applications: IP, WB PubMed
81 Chaux A et al. Dysregulation of the mammalian target of rapamycin pathway in chromophobe renal cell carcinomas. Hum. Pathol. 2013 Oct;44(10):2323-30
Chaux A et al
2013/01/01
Species: Human, Applications: IHC-P PubMed
82 Kaira K et al. Biological correlation of &#xB9;&#x2078;F-FDG uptake on PET in pulmonary neuroendocrine tumors. Anticancer Res. 2013 Oct;33(10):4219-28
Kaira K et al
2013/01/01
PubMed
83 Motzer RJ et al. Investigation of novel circulating proteins, germ line single-nucleotide polymorphisms, and molecular tumor markers as potential efficacy biomarkers of first-line sunitinib therapy for advanced renal cell carcinoma. Cancer Chemother. Phar
Motzer RJ et al
2014/01/01
Species: Human, Applications: IHC-P PubMed
84 Su EJ et al. Impaired Fetoplacental Angiogenesis in Growth-Restricted Fetuses With Abnormal Umbilical Artery Doppler Velocimetry Is Mediated by Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT). J. Clin. Endocrinol. Metab. 2015 Jan;100(1):E30-40
Su EJ et al
2015/01/01
Species: Human, Applications: IP PubMed
85 Xiao W et al. The importance of physiological oxygen concentrations in the sandwich cultures of rat hepatocytes on gas-permeable membranes. Biotechnol. Prog. 2014 Nov;30(6):1401-10
Xiao W et al
2014/01/01
PubMed
86 Bruns DR et al. Mitochondrial integrity in a neonatal bovine model of right ventricular dysfunction. Am. J. Physiol. Lung Cell Mol. Physiol. 2015 Jan;308(2):L158-67
Bruns DR et al
2015/01/01
PubMed
87 Niemi H et al. HIF-1&#x3B1; and HIF-2&#x3B1; induce angiogenesis and improve muscle energy recovery. Eur. J. Clin. Invest. 2014 Oct;44(10):989-99
Niemi H et al
2014/01/01
PubMed
88 H辿nique C et al. Increasing mitochondrial muscle fatty acid oxidation induces skeletal muscle remodeling toward an oxidative phenotype. FASEB J. 2015 Feb;
H辿nique C et al
2015/01/01
Species: Mouse, Applications: WB PubMed
89 Ohmoto T et al. CD44-expressing undifferentiated carcinoma with rhabdoid features of the pancreas: molecular analysis of aggressive invasion and metastasis. Pathol. Int. 2015 May;65(5):264-70
Ohmoto T et al
2015/01/01
Species: Human, Applications: IHC-P PubMed
90 Sun W et al. Interleukin-1&#x3B2; promotes hypoxia-induced apoptosis of glioblastoma cells by inhibiting hypoxia-inducible factor-1 mediated adrenomedullin production. Cell Death Dis 2014;5:e1020
Sun W et al
2014/01/01
Species: Human, Applications: WB PubMed
91 Ramamoorthy P et al. Ischemia induces different levels of hypoxia inducible factor-1&#x3B1; protein expression in interneurons and pyramidal neurons. Acta Neuropathol Commun 2014;2:51
Ramamoorthy P et al
2014/01/01
Species: Rat, Applications: ICC/IF PubMed
92 Obama T et al. Vascular induction of a disintegrin and metalloprotease 17 by angiotensin II through hypoxia inducible factor 1&#x3B1;. Am. J. Hypertens. 2015 Jan;28(1):10-4
Obama T et al
2015/01/01
PubMed
93 Brown NS et al. Cooperative stimulation of vascular endothelial growth factor expression by hypoxia and reactive oxygen species: the effect of targeting vascular endothelial growth factor and oxidative stress in an orthotopic xenograft model of bladder ca
Brown NS et al
2005/01/01
Species: Rat, Applications: WB PubMed
94 Chiavarina B et al. HIF1-alpha functions as a tumor promoter in cancer associated fibroblasts, and as a tumor suppressor in breast cancer cells: Autophagy drives compartment-specific oncogenesis. Cell Cycle 2010 Sep;9(17):3534-51
Chiavarina B et al
2010/01/01
Applications: ICC/IF PubMed
95 Uchida T et al. Prolonged hypoxia differentially regulates hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression in lung epithelial cells: implication of natural antisense HIF-1alpha. J. Biol. Chem. 2004 Apr;279(15):14871-8
Uchida T et al
2004/01/01
Species: Human, Applications: ICC/IF PubMed
96 Cabuk D et al. Vascular endothelial growth factor, hypoxia-inducible factor 1 alpha and CD34 expressions in early-stage gastric tumors: relationship with pathological factors and prognostic impact on survival. Oncology 2007;72(1-2):111-7
Cabuk D et al
2007/01/01
Species: Human PubMed
97 Martinez-Outschoorn UE et al. Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NF&#x3BA;B activation in the tumor stromal microenvironment. Cell Cycle 2010 Sep;9(17):3515-33
Martinez-Outschoorn UE et al
2010/01/01
Applications: ICC/IF PubMed
98 Evenou F et al. Spontaneous formation of highly functional three-dimensional multilayer from human hepatoma Hep G2 cells cultured on an oxygen-permeable polydimethylsiloxane membrane. Tissue Eng Part C Methods 2010 Apr;16(2):311-8
Evenou F et al
2010/01/01
Species: Human, Applications: IHC PubMed
99 Schultz L et al. Immunoexpression status and prognostic value of mTOR and hypoxia-induced pathway members in primary and metastatic clear cell renal cell carcinomas. Am. J. Surg. Pathol. 2011 Oct;35(10):1549-56
Schultz L et al
2011/01/01
Species: Human PubMed
100 Nordal RA et al. Hypoxia and hypoxia-inducible factor-1 target genes in central nervous system radiation injury: a role for vascular endothelial growth factor. Clin. Cancer Res. 2004 May;10(10):3342-53
Nordal RA et al
2004/01/01
Applications: ELISA PubMed
101 Monsef N et al. Localization of immunoreactive HIF-1alpha and HIF-2alpha in neuroendocrine cells of both benign and malignant prostate glands. Prostate 2007 Aug;67(11):1219-29
Monsef N et al
2007/01/01
Species: Human, Applications: ICC/IF PubMed
102 Isaacs JS et al. HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability. Cancer Cell 2005 Aug;8(2):143-53
Isaacs JS et al
2005/01/01
Species: Human, Applications: ELISA PubMed
103 L坦pez-Avil辿s S et al. Activation of Srk1 by the mitogen-activated protein kinase Sty1/Spc1 precedes its dissociation from the kinase and signals its degradation. Mol. Biol. Cell 2008 Apr;19(4):1670-9
L坦pez-Avil辿s S et al
2008/01/01
Applications: ELISA PubMed
104 Caron A et al. Kidney ischemia-reperfusion regulates expression and distribution of tubulin subunits, beta-actin and rho GTPases in proximal tubules. Arch. Biochem. Biophys. 2004 Nov;431(1):31-46
Caron A et al
2004/01/01
Species: Rat PubMed
105 Virmani S et al. Comparison of hypoxia-inducible factor-1alpha expression before and after transcatheter arterial embolization in rabbit VX2 liver tumors. J Vasc Interv Radiol 2008 Oct;19(10):1483-9
Virmani S et al
2008/01/01
Applications: IHC PubMed
106 Seagroves TN et al. HIF1alpha is a critical regulator of secretory differentiation and activation, but not vascular expansion, in the mouse mammary gland. Development 2003 Apr;130(8):1713-24
Seagroves TN et al
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107 Isaacs JT et al. Identification of ABR-215050 as lead second generation quinoline-3-carboxamide anti-angiogenic agent for the treatment of prostate cancer. Prostate 2006 Dec;66(16):1768-78
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108 Monsef N et al. HIF1alpha isoforms in benign and malignant prostate tissue and their correlation to neuroendocrine differentiation. BMC Cancer 2010;10:385
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109 Kaira K et al. Depolarized MUC1 expression is closely associated with hypoxic markers and poor outcome in resected non-small cell lung cancer. Int. J. Surg. Pathol. 2012 Jun;20(3):223-32
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110 Li YM et al. A hypoxia-independent hypoxia-inducible factor-1 activation pathway induced by phosphatidylinositol-3 kinase/Akt in HER2 overexpressing cells. Cancer Res. 2005 Apr;65(8):3257-63
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111 Murphy BJ et al. The metal-responsive transcription factor-1 contributes to HIF-1 activation during hypoxic stress. Biochem. Biophys. Res. Commun. 2005 Nov;337(3):860-7
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112 Albina JE et al. HIF-1 expression in healing wounds: HIF-1alpha induction in primary inflammatory cells by TNF-alpha. Am. J. Physiol., Cell Physiol. 2001 Dec;281(6):C1971-7
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113 Monzon FA et al. Chromosome 14q loss defines a molecular subtype of clear-cell renal cell carcinoma associated with poor prognosis. Mod. Pathol. 2011 Nov;24(11):1470-9
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114 Gagnon PM et al. Temporal and genetic influences on protection against noise-induced hearing loss by hypoxic preconditioning in mice. Hear. Res. 2007 Apr;226(1-2):79-91
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115 Luyendyk JP et al. Role of hepatic fibrin in idiosyncrasy-like liver injury from lipopolysaccharide-ranitidine coexposure in rats. Hepatology 2004 Dec;40(6):1342-51
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116 Ioannou M et al. Validated analysis of HIF-1alpha expression in cancer cells using a controlled and comparative immunoassay. Oncol. Rep. 2010 Jul;24(1):161-9
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117 Kim JI et al. Correlation of volumetric perfusion CT parameters with hypoxia inducible factor-1 alpha expression in a rabbit VX2 tumor model. Acta Radiol 2016 Jun;57(6):708-15
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118 Kim CM et al. Expression of hypoxia inducible factor-1alpha and 2alpha in genetically distinct early renal cortical tumors. J. Urol. 2006 May;175(5):1908-14
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119 Kaira K et al. LAT1 expression is closely associated with hypoxic markers and mTOR in resected non-small cell lung cancer. Am J Transl Res 2011;3(5):468-78
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120 Choudhury KR et al. A robust automated measure of average antibody staining in immunohistochemistry images. J. Histochem. Cytochem. 2010 Feb;58(2):95-107
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121 Tandon R et al. Identification of human endogenous retrovirus-specific T cell responses in vertically HIV-1-infected subjects. J. Virol. 2011 Nov;85(21):11526-31
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122 Gross J et al. Apoptosis, necrosis and hypoxia inducible factor-1 in human head and neck squamous cell carcinoma cultures. Int. J. Oncol. 2005 Sep;27(3):807-14
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123 Kaira K et al. L-type amino acid transporter 1 (LAT1) expression in malignant pleural mesothelioma. Anticancer Res. 2011 Dec;31(12):4075-82
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124 Mayer A et al. Differential expression of HIF-1 in glioblastoma multiforme and anaplastic astrocytoma. Int. J. Oncol. 2012 Oct;41(4):1260-70
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125 Michelsen J et al. Tissue expression and plasma levels of adrenomedullin in renal cancer patients. Clin. Sci. 2006 Jul;111(1):61-70
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126 Cangul H. Hypoxia upregulates the expression of the NDRG1 gene leading to its overexpression in various human cancers. BMC Genet. 2004 Sep;5:27
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127 Tirziu D et al. Endothelial nuclear factor-&#x3BA;B-dependent regulation of arteriogenesis and branching. Circulation 2012 Nov;126(22):2589-600
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128 Kaira K et al. Expression of 4F2hc (CD98) in pulmonary neuroendocrine tumors. Oncol. Rep. 2011 Oct;26(4):931-7
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129 Reichner JS et al. Determination of the role of hypoxia-inducible factor 1 in wound healing. Meth. Enzymol. 2004;381:527-38
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130 Bernaudin M et al. Methods to detect hypoxia-induced ischemic tolerance in the brain. Meth. Enzymol. 2004;381:399-416
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131 Wang L et al. Effects of 17&#x3B2;-estradiol and 2-methoxyestradiol on the oxidative stress-hypoxia inducible factor-1 pathway in hypoxic pulmonary hypertensive rats. Exp Ther Med 2017 May;13(5):2537-2543
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132 Megele R et al. Intra-tumoral treatment with oxygen-ozone in glioblastoma: A systematic literature search and results of a case series. Oncol Lett 2018 Nov;16(5):5813-5822
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133 Chen CW et al. Increased risk of brain cancer incidence in stroke patients: a clinical case series, population-based and longitudinal follow-up study. Oncotarget 2017 Dec;8(65):108989-108999
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134 Tickoo SK et al. Hypoxia-inducible factor and mammalian target of rapamycin pathway markers in urothelial carcinoma of the bladder: possible therapeutic implications. BJU Int. 2011 Mar;107(5):844-849
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135 Puchert M et al. Astrocytic expression of the CXCL12 receptor, CXCR7/ACKR3 is a hallmark of the diseased, but not developing CNS. Mol. Cell. Neurosci. 2017 12;85:105-118
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136 Jablonska B et al. Sirt1 regulates glial progenitor proliferation and regeneration in white matter after neonatal brain injury. Nat Commun 2016 12;7:13866
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137 Timpano S et al. Human Cells Cultured under Physiological Oxygen Utilize Two Cap-binding Proteins to recruit Distinct mRNAs for Translation. J. Biol. Chem. 2016 May;291(20):10772-82
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138 Fujimoto Y et al. Low Cardiac Output Leads Hepatic Fibrosis in Right Heart Failure Model Rats. PLoS ONE 2016;11(2):e0148666
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139 Yang C et al. B cells promote tumor progression via STAT3 regulated-angiogenesis. PLoS ONE 2013;8(5):e64159
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140 Tong D et al. The HIF/PHF8/AR axis promotes prostate cancer progression. Oncogenesis 2016 Dec;5(12):e283
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141 Cai T et al. Sodium-glucose cotransporter 2 inhibition suppresses HIF-1&#x3B1;-mediated metabolic switch from lipid oxidation to glycolysis in kidney tubule cells of diabetic mice. Cell Death Dis 2020 05;11(5):390
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142 Gaba RC et al. Conventional versus drug-eluting embolic transarterial chemoembolization with doxorubicin: comparative drug delivery, pharmacokinetics, and treatment response in a rabbit VX2 tumor model. Drug Deliv Transl Res 2021 Apr;
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143 Favier FB et al. Endurance training prevents negative effects of the hypoxia mimetic dimethyloxalylglycine on cardiac and skeletal muscle function. J Appl Physiol (1985) 2016 Feb;120(4):455-63
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144 Wang N et al. Hypoxia-inducible factor-1 mediates pancreatic &#x3B2;-cell dysfunction by intermittent hypoxia. Am J Physiol Cell Physiol 2020 11;319(5):C922-C932
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    Weroha SJ et al. Phase II trial of lapatinib and topotecan (LapTop) in patients with platinum-refractory/resistant ovarian and primary peritoneal carcinoma. Gynecol. Oncol. 2011 Jul;122(1):116-20
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    PubMed
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    Park HJ et al. Hypoxia inducible factor-1&#x3B1; directly induces the expression of receptor activator of nuclear factor-&#x3BA;B ligand in periodontal ligament fibroblasts. Mol. Cells 2011 Jun;31(6):573-8
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    Kaira K et al. Thymidylate synthase expression is closely associated with outcome in patients with pulmonary adenocarcinoma. Med. Oncol. 2011 Sep;
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    Kaira K et al. MUC1 expression in pulmonary metastatic tumors: a comparison of primary lung cancer. Pathol. Oncol. Res. 2012 Apr;18(2):439-47
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    Chu W et al. Mild hypoxia induced cardiomyocyte hypertrophy via up-regulation of HIF-1&#x3B1;-mediated TRPC signaling. J. Cell. Mol. Med. 2011 Nov;
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    Jeong CW et al. The Role of Hypoxia-Inducible Factor-1&#x3B1; and -2&#x3B1; in Androgen Insensitive Prostate Cancer Cells. Urol Oncol 2012 Apr;
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    Weber DC et al. The prognostic value of expression of HIF1&#x3B1;, EGFR and VEGF-A, in localized prostate cancer for intermediate- and high-risk patients treated with radiation therapy with or without androgen deprivation therapy. Radiat Oncol 2012;7:66
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    Mhawech-Fauceglia P et al. The role of hypoxic-inducible factor (HIF1&#x3B1;) and aldolaseC protein in endometrial carcinogenesis: a retrospective study of 279 patients. BMJ Open 2012;2(4)
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    PubMed
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    Pang X, Wang Z, Yin D, Zhang Z. Overexpression of hypoxia-inducible factor prolyl- hydoxylase attenuated by HCG-induced vascular endothelial growth factor expression in luteal cells. African Journal of Biotechnology 10(42):8227-8235.

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    Jiang W et al. Identification of a molecular signature underlying inhibition of mammary carcinoma growth by dietary N-3 fatty acids. Cancer Res. 2012 Aug;72(15):3795-806
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    Kishimoto K et al. Hypoxia-induced up-regulation of angiogenin, besides VEGF, is related to progression of oral cancer. Oral Oncol 2012 Jun;
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    Species: Human, Applications: WB, IHC
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    PubMed
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    Kaira K, Oriuchi N, Takahashi T, et al. LAT1 expression is closely associated with hypoxic markers and mTOR in resected non-small cell lung cancer. Am J Translational Res;3(5):468-478. 2010.

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    Chiavarina B et al. Metabolic reprogramming and two-compartment tumor metabolism: opposing role(s) of HIF1&#x3B1; and HIF2&#x3B1; in tumor-associated fibroblasts and human breast cancer cells. Cell Cycle 2012 Sep;11(17):3280-9
    Chiavarina B et al
    2012/01/01
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    Applications: WB, ICC/IF
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    PubMed
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    Ding A et al. Chronic treatment with tempol does not significantly ameliorate renal tissue hypoxia or disease progression in a rodent model of polycystic kidney disease. Clin. Exp. Pharmacol. Physiol. 2012 Nov;39(11):917-29
    Ding A et al
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    Applications: IHC, ICC/IF
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    PubMed
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    Galzio R et al. Hypoxia modulation of peroxisome proliferator-activated receptors (PPARs) in human glioblastoma stem cells. Implications for therapy. J. Cell. Biochem. 2012 Nov;113(11):3342-52
    Galzio R et al
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    Applications: FLOW, ICC/IF
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    PubMed
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    Clarke DN et al. Perlecan Domain V Induces VEGf Secretion in Brain Endothelial Cells through Integrin &#x3B1;(5)&#x3B2;(1) and ERK-Dependent Signaling Pathways. PLoS ONE 2012;7(9):e45257
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    2012/01/01
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    Applications: WB
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    PubMed
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    Zhao Y et al. Targeting Cullin-RING ligases by MLN4924 induces autophagy via modulating the HIF1-REDD1-TSC1-mTORC1-DEPTOR axis. Cell Death Dis 2012;3:e386
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    Applications: WB
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    PubMed
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    Ioannou M et al. Upregulation of VEGF expression is associated with accumulation of HIF-1&#x3B1; in the skin of na&#xEF;ve scleroderma patients. Mod Rheumatol 2012 Oct;
    Ioannou M et al
    2012/01/01
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    Species: Human, Applications: IHC
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    PubMed
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    Shinmei S et al. MicroRNA-155 is a predictive marker for survival in patients with clear cell renal cell carcinoma. Int. J. Urol. 2012 Oct;
    Shinmei S et al
    2012/01/01
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    Species: Human, Applications: IHC
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    PubMed
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    Kaira K et al. Biologic correlates of &#xB9;&#x2078;F-FDG uptake on PET in pulmonary pleomorphic carcinoma. Lung Cancer 2011 Feb;71(2):144-50
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    Species: Human, Applications: IHC
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    PubMed
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    Brenner RM et al. Molecular and functional aspects of menstruation in the macaque. Rev Endocr Metab Disord 2012 Oct;
    Brenner RM et al
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    Species: Avian, Applications: IHC
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    PubMed
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  • 文献情報:
    Lundgrin EL et al. Fasting 2-Deoxy-2-[18F]fluoro-D-glucose Positron Emission Tomography to Detect Metabolic Changes in Pulmonary Arterial Hypertension Hearts over 1 Year. Ann Am Thorac Soc 2013 Feb;10(1):1-9
    Lundgrin EL et al
    2013/01/01
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    Species: Human, Applications: IHC-P
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    PubMed
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    Chaux A et al. Immunoexpression status and prognostic value of mammalian target of rapamycin and hypoxia-induced pathway members in papillary cell renal cell carcinomas. Hum. Pathol. 2012 Dec;43(12):2129-37
    Chaux A et al
    2012/01/01
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    Species: Human, Applications: IHC
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    PubMed
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    Kaira K et al. Biologic correlation of 2-[18F]-fluoro-2-deoxy-D-glucose uptake on positron emission tomography in thymic epithelial tumors. J. Clin. Oncol. 2010 Aug;28(23):3746-53
    Kaira K et al
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    Species: Human, Applications: IHC
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    PubMed
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  • 文献情報:
    Gu HF et al. Impact of the hypoxia-inducible factor-1 &#x3B1; (HIF1A) Pro582Ser polymorphism on diabetes nephropathy. Diabetes Care 2013 Feb;36(2):415-21
    Gu HF et al
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    Species: Mouse, Applications: IHC-P
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    PubMed
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    Reddy VD et al. Alcohol-induced oxidative/nitrosative stress alters brain mitochondrial membrane properties. Mol. Cell. Biochem. 2013 Mar;375(1-2):39-47
    Reddy VD et al
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    Species: Rat, Applications: WB
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    PubMed
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  • 文献情報:
    Aziz SA et al. Expression of drug targets in primary and matched metastatic renal cell carcinoma tumors. BMC Clin Pathol 2013;13(1):3
    Aziz SA et al
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    Species: Human, Applications: IHC
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    PubMed
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  • 文献情報:
    G旦ssl M et al. Low vasa vasorum densities correlate with inflammation and subintimal thickening: potential role in location--determination of atherogenesis. Atherosclerosis 2009 Oct;206(2):362-8
    G旦ssl M et al
    2009/01/01
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    Species: Porcine, Applications: IHC
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    PubMed
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    Toba H et al. 18F-fluorodeoxyglucose positron emission tomography/computed tomography and the relationship between fluorodeoxyglucose uptake and the expression of hypoxia-inducible factor-1&#x3B1;, glucose transporter-1 and vascular endothelial growth fac
    Toba H et al
    2013/01/01
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    Species: Human, Applications: IHC-P
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    PubMed
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    Flynn JR et al. Hypoxia-regulated protein expression, patient characteristics, and preoperative imaging as predictors of survival in adults with glioblastoma multiforme. Cancer 2008 Sep;113(5):1032-42
    Flynn JR et al
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    Species: Human, Applications: IHC-P
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    PubMed
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    Kar AN et al. Intra-axonal synthesis of eukaryotic translation initiation factors regulates local protein synthesis and axon growth in rat sympathetic neurons. J. Neurosci. 2013 Apr;33(17):7165-74
    Kar AN et al
    2013/01/01
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    Species: Rat, Applications: WB
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    PubMed
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    Evenou F et al. Gas-permeable membranes and co-culture with fibroblasts enable high-density hepatocyte culture as multilayered liver tissues. Biotechnol. Prog. 2011 Jul;27(4):1146-53
    Evenou F et al
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    Species: Mouse, Applications: IHC-P, ICC/IF
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    PubMed
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    Kaira K, Oriuchi N, Takahashi T et al. LAT1 expression is closely associated with hypoxic markers and mTOR in resected non-small cell lung cancer. Am J Translational Res;3(5):468-478. 2010

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    PubMed
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    Tanaka T et al. Indoxyl sulfate signals for rapid mRNA stabilization of Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2 (CITED2) and suppresses the expression of hypoxia-inducible genes in experimental CKD and uremia. FASEB
    Tanaka T et al
    2013/01/01
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    Species: Human, Applications: WB, ChIP
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    PubMed
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  • 文献情報:
    Sceneay J et al. The antioxidant N-acetylcysteine prevents HIF-1 stabilization under hypoxia in vitro but does not affect tumorigenesis in multiple breast cancer models in vivo. PLoS ONE 2013;8(6):e66388
    Sceneay J et al
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    Species: Mouse, Applications: WB, ICC/IF
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    PubMed
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    Salem AF et al. Downregulation of stromal BRCA1 drives breast cancer tumor growth via upregulation of HIF-1&#x3B1;, autophagy and ketone body production. Cell Cycle 2012 Nov;11(22):4167-73
    Salem AF et al
    2012/01/01
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    Species: Human, Applications: WB
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    PubMed
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  • 文献情報:
    Namas RA et al. Hypoxia-induced overexpression of BNIP3 is not dependent on hypoxia-inducible factor 1&#x3B1; in mouse hepatocytes. Shock 2011 Aug;36(2):196-202
    Namas RA et al
    2011/01/01
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    Species: Mouse, Applications: WB
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    PubMed
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    Li J et al. Alpha-calcitonin gene-related peptide is protective against pressure overload-induced heart failure. Regul. Pept. 2013 Jun;185C:20-28
    Li J et al
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    Species: Mouse, Applications: WB
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    PubMed
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  • 文献情報:
    Li C et al. The mechanisms of chansu in inducing efficient apoptosis in colon cancer cells. Evid Based Complement Alternat Med 2013;2013:849054
    Li C et al
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    Species: Human, Applications: ICC/IF
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    PubMed
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    Diensthuber M et al. Expression of bcl-2 is associated with microvessel density in olfactory neuroblastoma. J. Neurooncol. 2008 Sep;89(2):131-9
    Diensthuber M et al
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    Applications: IHC-P
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    PubMed
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  • 文献情報:
    Tezel G et al. Hypoxia-inducible factor 1alpha in the glaucomatous retina and optic nerve head. Arch. Ophthalmol. 2004 Sep;122(9):1348-56
    Tezel G et al
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    Species: Human, Applications: IHC-P
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    Anderson KM et al. The proliferative response of hela cells to 2-deoxy-D-glucose under hypoxic or anoxic conditions: an analogue for studying some properties of in vivo solid cancers. Anticancer Res. ;26(6B):4155-62
    Anderson KM et al
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    Species: Human, Applications: IHC, WB
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    Zheng X et al. Cell-type-specific regulation of degradation of hypoxia-inducible factor 1 alpha: role of subcellular compartmentalization. Mol. Cell. Biol. 2006 Jun;26(12):4628-41
    Zheng X et al
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    Species: Rabbit, Applications: IP, WB
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    PubMed
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    Chaux A et al. Dysregulation of the mammalian target of rapamycin pathway in chromophobe renal cell carcinomas. Hum. Pathol. 2013 Oct;44(10):2323-30
    Chaux A et al
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    Species: Human, Applications: IHC-P
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    PubMed
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    Kaira K et al. Biological correlation of &#xB9;&#x2078;F-FDG uptake on PET in pulmonary neuroendocrine tumors. Anticancer Res. 2013 Oct;33(10):4219-28
    Kaira K et al
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    PubMed
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    Motzer RJ et al. Investigation of novel circulating proteins, germ line single-nucleotide polymorphisms, and molecular tumor markers as potential efficacy biomarkers of first-line sunitinib therapy for advanced renal cell carcinoma. Cancer Chemother. Phar
    Motzer RJ et al
    2014/01/01
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    Species: Human, Applications: IHC-P
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    PubMed
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  • 文献情報:
    Su EJ et al. Impaired Fetoplacental Angiogenesis in Growth-Restricted Fetuses With Abnormal Umbilical Artery Doppler Velocimetry Is Mediated by Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT). J. Clin. Endocrinol. Metab. 2015 Jan;100(1):E30-40
    Su EJ et al
    2015/01/01
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    Species: Human, Applications: IP
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    PubMed
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    Xiao W et al. The importance of physiological oxygen concentrations in the sandwich cultures of rat hepatocytes on gas-permeable membranes. Biotechnol. Prog. 2014 Nov;30(6):1401-10
    Xiao W et al
    2014/01/01
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  • 参照:
    PubMed
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    Bruns DR et al. Mitochondrial integrity in a neonatal bovine model of right ventricular dysfunction. Am. J. Physiol. Lung Cell Mol. Physiol. 2015 Jan;308(2):L158-67
    Bruns DR et al
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    PubMed
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    Niemi H et al. HIF-1&#x3B1; and HIF-2&#x3B1; induce angiogenesis and improve muscle energy recovery. Eur. J. Clin. Invest. 2014 Oct;44(10):989-99
    Niemi H et al
    2014/01/01
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    PubMed
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    H辿nique C et al. Increasing mitochondrial muscle fatty acid oxidation induces skeletal muscle remodeling toward an oxidative phenotype. FASEB J. 2015 Feb;
    H辿nique C et al
    2015/01/01
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    Species: Mouse, Applications: WB
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    PubMed
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  • 文献情報:
    Ohmoto T et al. CD44-expressing undifferentiated carcinoma with rhabdoid features of the pancreas: molecular analysis of aggressive invasion and metastasis. Pathol. Int. 2015 May;65(5):264-70
    Ohmoto T et al
    2015/01/01
  • 備考:
    Species: Human, Applications: IHC-P
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    PubMed
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  • 文献情報:
    Sun W et al. Interleukin-1&#x3B2; promotes hypoxia-induced apoptosis of glioblastoma cells by inhibiting hypoxia-inducible factor-1 mediated adrenomedullin production. Cell Death Dis 2014;5:e1020
    Sun W et al
    2014/01/01
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    Species: Human, Applications: WB
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    PubMed
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  • 文献情報:
    Ramamoorthy P et al. Ischemia induces different levels of hypoxia inducible factor-1&#x3B1; protein expression in interneurons and pyramidal neurons. Acta Neuropathol Commun 2014;2:51
    Ramamoorthy P et al
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    Species: Rat, Applications: ICC/IF
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    PubMed
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  • 文献情報:
    Obama T et al. Vascular induction of a disintegrin and metalloprotease 17 by angiotensin II through hypoxia inducible factor 1&#x3B1;. Am. J. Hypertens. 2015 Jan;28(1):10-4
    Obama T et al
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    PubMed
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    Brown NS et al. Cooperative stimulation of vascular endothelial growth factor expression by hypoxia and reactive oxygen species: the effect of targeting vascular endothelial growth factor and oxidative stress in an orthotopic xenograft model of bladder ca
    Brown NS et al
    2005/01/01
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    Species: Rat, Applications: WB
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    PubMed
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  • 文献情報:
    Chiavarina B et al. HIF1-alpha functions as a tumor promoter in cancer associated fibroblasts, and as a tumor suppressor in breast cancer cells: Autophagy drives compartment-specific oncogenesis. Cell Cycle 2010 Sep;9(17):3534-51
    Chiavarina B et al
    2010/01/01
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    Applications: ICC/IF
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    PubMed
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  • 文献情報:
    Uchida T et al. Prolonged hypoxia differentially regulates hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression in lung epithelial cells: implication of natural antisense HIF-1alpha. J. Biol. Chem. 2004 Apr;279(15):14871-8
    Uchida T et al
    2004/01/01
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    Species: Human, Applications: ICC/IF
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    PubMed
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  • 文献情報:
    Cabuk D et al. Vascular endothelial growth factor, hypoxia-inducible factor 1 alpha and CD34 expressions in early-stage gastric tumors: relationship with pathological factors and prognostic impact on survival. Oncology 2007;72(1-2):111-7
    Cabuk D et al
    2007/01/01
  • 備考:
    Species: Human
  • 参照:
    PubMed
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  • 文献情報:
    Martinez-Outschoorn UE et al. Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NF&#x3BA;B activation in the tumor stromal microenvironment. Cell Cycle 2010 Sep;9(17):3515-33
    Martinez-Outschoorn UE et al
    2010/01/01
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    Applications: ICC/IF
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    PubMed
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  • 文献情報:
    Evenou F et al. Spontaneous formation of highly functional three-dimensional multilayer from human hepatoma Hep G2 cells cultured on an oxygen-permeable polydimethylsiloxane membrane. Tissue Eng Part C Methods 2010 Apr;16(2):311-8
    Evenou F et al
    2010/01/01
  • 備考:
    Species: Human, Applications: IHC
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    PubMed
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  • 文献情報:
    Schultz L et al. Immunoexpression status and prognostic value of mTOR and hypoxia-induced pathway members in primary and metastatic clear cell renal cell carcinomas. Am. J. Surg. Pathol. 2011 Oct;35(10):1549-56
    Schultz L et al
    2011/01/01
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    Species: Human
  • 参照:
    PubMed
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  • 文献情報:
    Nordal RA et al. Hypoxia and hypoxia-inducible factor-1 target genes in central nervous system radiation injury: a role for vascular endothelial growth factor. Clin. Cancer Res. 2004 May;10(10):3342-53
    Nordal RA et al
    2004/01/01
  • 備考:
    Applications: ELISA
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    PubMed
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  • 文献情報:
    Monsef N et al. Localization of immunoreactive HIF-1alpha and HIF-2alpha in neuroendocrine cells of both benign and malignant prostate glands. Prostate 2007 Aug;67(11):1219-29
    Monsef N et al
    2007/01/01
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    Species: Human, Applications: ICC/IF
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    PubMed
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  • 文献情報:
    Isaacs JS et al. HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability. Cancer Cell 2005 Aug;8(2):143-53
    Isaacs JS et al
    2005/01/01
  • 備考:
    Species: Human, Applications: ELISA
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    PubMed
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  • 文献情報:
    L坦pez-Avil辿s S et al. Activation of Srk1 by the mitogen-activated protein kinase Sty1/Spc1 precedes its dissociation from the kinase and signals its degradation. Mol. Biol. Cell 2008 Apr;19(4):1670-9
    L坦pez-Avil辿s S et al
    2008/01/01
  • 備考:
    Applications: ELISA
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    PubMed
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  • 文献情報:
    Caron A et al. Kidney ischemia-reperfusion regulates expression and distribution of tubulin subunits, beta-actin and rho GTPases in proximal tubules. Arch. Biochem. Biophys. 2004 Nov;431(1):31-46
    Caron A et al
    2004/01/01
  • 備考:
    Species: Rat
  • 参照:
    PubMed
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  • 文献情報:
    Virmani S et al. Comparison of hypoxia-inducible factor-1alpha expression before and after transcatheter arterial embolization in rabbit VX2 liver tumors. J Vasc Interv Radiol 2008 Oct;19(10):1483-9
    Virmani S et al
    2008/01/01
  • 備考:
    Applications: IHC
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    PubMed
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  • 文献情報:
    Seagroves TN et al. HIF1alpha is a critical regulator of secretory differentiation and activation, but not vascular expansion, in the mouse mammary gland. Development 2003 Apr;130(8):1713-24
    Seagroves TN et al
    2003/01/01
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    Applications: WB
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    PubMed
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  • 文献情報:
    Isaacs JT et al. Identification of ABR-215050 as lead second generation quinoline-3-carboxamide anti-angiogenic agent for the treatment of prostate cancer. Prostate 2006 Dec;66(16):1768-78
    Isaacs JT et al
    2006/01/01
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    Applications: ICC/IF
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    PubMed
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  • 文献情報:
    Monsef N et al. HIF1alpha isoforms in benign and malignant prostate tissue and their correlation to neuroendocrine differentiation. BMC Cancer 2010;10:385
    Monsef N et al
    2010/01/01
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    Species: Human, Applications: IHC
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    PubMed
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    Kaira K et al. Depolarized MUC1 expression is closely associated with hypoxic markers and poor outcome in resected non-small cell lung cancer. Int. J. Surg. Pathol. 2012 Jun;20(3):223-32
    Kaira K et al
    2012/01/01
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    Species: Human
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    PubMed
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  • 文献情報:
    Li YM et al. A hypoxia-independent hypoxia-inducible factor-1 activation pathway induced by phosphatidylinositol-3 kinase/Akt in HER2 overexpressing cells. Cancer Res. 2005 Apr;65(8):3257-63
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    Murphy BJ et al. The metal-responsive transcription factor-1 contributes to HIF-1 activation during hypoxic stress. Biochem. Biophys. Res. Commun. 2005 Nov;337(3):860-7
    Murphy BJ et al
    2005/01/01
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    Species: Mouse, Applications: WB
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    PubMed
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  • 文献情報:
    Albina JE et al. HIF-1 expression in healing wounds: HIF-1alpha induction in primary inflammatory cells by TNF-alpha. Am. J. Physiol., Cell Physiol. 2001 Dec;281(6):C1971-7
    Albina JE et al
    2001/01/01
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    Species: Rat
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    PubMed
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    Monzon FA et al. Chromosome 14q loss defines a molecular subtype of clear-cell renal cell carcinoma associated with poor prognosis. Mod. Pathol. 2011 Nov;24(11):1470-9
    Monzon FA et al
    2011/01/01
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    Species: Human, Applications: IHC
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    PubMed
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    Gagnon PM et al. Temporal and genetic influences on protection against noise-induced hearing loss by hypoxic preconditioning in mice. Hear. Res. 2007 Apr;226(1-2):79-91
    Gagnon PM et al
    2007/01/01
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    Species: Mouse, Applications: WB
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    PubMed
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    Luyendyk JP et al. Role of hepatic fibrin in idiosyncrasy-like liver injury from lipopolysaccharide-ranitidine coexposure in rats. Hepatology 2004 Dec;40(6):1342-51
    Luyendyk JP et al
    2004/01/01
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    Species: Rat, Applications: IHC
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    PubMed
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    Ioannou M et al. Validated analysis of HIF-1alpha expression in cancer cells using a controlled and comparative immunoassay. Oncol. Rep. 2010 Jul;24(1):161-9
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    Species: Human, Applications: WB
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    PubMed
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