価格表

在庫・価格 : 2025年04月28日 17時18分 現在

商品名 商品コード メーカー 包装 価格 在庫 リスト
Anti-MTH1, Rabbit-Poly
データシート
NB100-109 NOVノバス バイオロジカルス
Novus biologicals, LLC
200 μl ¥108,000
(未発注)
追加

在庫・価格 : 2025年04月28日 17時18分 現在

Anti-MTH1, Rabbit-Poly

  • 商品コード:NB100-109
  • メーカー:NOV
  • 包装:200μl
  • 価格: ¥108,000
  • 在庫:無(未発注)
使用文献
No. 文献情報 備考 参照
1 Takeshita F et al. Mechanistic approach of contrasting modifying effects of caffeine on carcinogenesis in the rat colon and mammary gland induced with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. Cancer Lett. 2003 May;194(1):25-35
Takeshita F et al
2003/01/01
western, immunohistochemistry-paraffin, rat PubMed
2 Kennedy CH et al. Expression of human MutT homologue (hMTH1) protein in primary non-small-cell lung carcinomas and histologically normal surrounding tissue. Free Radic. Biol. Med. 2003 Jun;34(11):1447-57
Kennedy CH et al
2003/01/01
western and Immunohistochemistry-frozen, human PubMed
3 Rai P et al. Enhanced elimination of oxidized guanine nucleotides inhibits oncogenic RAS-induced DNA damage and premature senescence. Oncogene 2011 Mar;30(12):1489-96
Rai P et al
2011/01/01
PubMed
4 Rai P et al. Continuous elimination of oxidized nucleotides is necessary to prevent rapid onset of cellular senescence. Proc. Natl. Acad. Sci. U.S.A. 2009 Jan;106(1):169-74
Rai P et al
2009/01/01
PubMed
5 Chang IY et al. Acute responses of DNA repair proteins and StarD6 in rat hippocampus after domoic acid-induced excitotoxicity. Acta Histochem. 2012 Aug;
Chang IY et al
2012/01/01
Species: Mouse, Applications: WB PubMed
6 Sheng Z et al. 8-Oxoguanine causes neurodegeneration during MUTYH-mediated DNA base excision repair. J. Clin. Invest. 2012 Dec;122(12):4344-61
Sheng Z et al
2012/01/01
Species: Mouse, Applications: IHC, ICC/IF PubMed
7 Patel A et al. MutT Homolog 1 (MTH1) maintains multiple KRAS-driven pro-malignant pathways. Oncogene 2014 Jul;
Patel A et al
2014/01/01
Species: Human, Applications: WB PubMed
8 Huber KV et al. Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy. Nature 2014 Apr;508(7495):222-7
Huber KV et al
2014/01/01
Species: Human, Applications: WB PubMed
9 Carter M et al. Crystal structure, biochemical and cellular activities demonstrate separate functions of MTH1 and MTH2. Nat Commun 2015;6:7871
Carter M et al
2015/01/01
Species: Human, Applications: WB PubMed
10 Bruel L et al. α-Galactosidase/sucrose kinase (AgaSK), a novel bifunctional enzyme from the human microbiome coupling galactosidase and kinase activities. J. Biol. Chem. 2011 Nov;286(47):40814-23
Bruel L et al
2011/01/01
PubMed
11 Giribaldi MG et al. MTH1 expression is required for effective transformation by oncogenic HRAS. Oncotarget 2015 May;6(13):11519-29
Giribaldi MG et al
2015/01/01
PubMed
12 Huber KV et al. Proteome-wide drug and metabolite interaction mapping by thermal-stability profiling. Nat. Methods 2015 Nov;12(11):1055-7
Huber KV et al
2015/01/01
PubMed
13 Hashiguchi K et al. The roles of human MTH1, MTH2 and MTH3 proteins in maintaining genome stability under oxidative stress. Mutat. Res. 2018 Mar;808:10-19
Hashiguchi K et al
2018/01/01
Species: Human, Applications: WB PubMed
14 Eshtad S et al. hMYH and hMTH1 cooperate for survival in mismatch repair defective T-cell acute lymphoblastic leukemia. Oncogenesis 2016 Dec;5(12):e275
Eshtad S et al
2016/01/01
Species: Human, Applications: WB PubMed
15 Bonora M et al. Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition. Oncogene 2015 Mar;34(12):1608
Bonora M et al
2015/01/01
PubMed
16 Fan J et al. Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway. J. Lipid Res. 2018 May;59(5):830-842
Fan J et al
2018/01/01
WB PubMed
17 Zhou H et al. Human MutT homologue 1 mRNA overexpression correlates to poor response of multiple myeloma. Int. J. Hematol. 2017 Mar;105(3):318-325
Zhou H et al
2017/01/01
Species: Human, Applications: PubMed
18 Page BDG et al. Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells. Nat Commun 2018 01;9(1):250
Page BDG et al
2018/01/01
Species: Human, Applications: WB PubMed
19 Zou X et al. Validating the concept of mutational signatures with isogenic cell models. Nat Commun 2018 May;9(1):1744
Zou X et al
2018/01/01
WB PubMed
20 Bialkowski K et al. A profile of 8-oxo-dGTPase activities in the NCI-60 human cancer panel: Meta-analytic insight into the regulation and role of MTH1 (NUDT1) gene expression in carcinogenesis. Free Radic Biol Med 2020 02;148:1-21
Bialkowski K et al
2020/01/01
PubMed
21 Godoy PRDV et al. Targeting NRF2, Regulator of Antioxidant System, to Sensitize Glioblastoma Neurosphere Cells to Radiation-Induced Oxidative Stress. Oxid Med Cell Longev 2020;2020:2534643
Godoy PRDV et al
2020/01/01
PubMed
22 Wang J et al. The Epstein-Barr virus nuclear antigen-1 upregulates the cellular antioxidant defense to enable B-cell growth transformation and immortalization. Oncogene 2020 01;39(3):603-616
Wang J et al
2020/01/01
PubMed
23 McPherson LA et al. Increased MTH1-specific 8-oxodGTPase activity is a hallmark of cancer in colon, lung and pancreatic tissue. DNA Repair (Amst) 2019 11;83:102644
McPherson LA et al
2019/01/01
PubMed
24 Arczewska KD et al. hMTH1 and GPX1 expression in human thyroid tissue is interrelated to prevent oxidative DNA damage. DNA Repair (Amst) 2020 11;95:102954
Arczewska KD et al
2020/01/01
PubMed
25 Moukengue B et al. TH1579, MTH1 inhibitor, delays tumour growth and inhibits metastases development in osteosarcoma model. EBioMedicine 2020 Mar;53:102704
Moukengue B et al
2020/01/01
PubMed
26 Rudd SG et al. MTH1 Inhibitor TH588 Disturbs Mitotic Progression and Induces Mitosis-Dependent Accumulation of Genomic 8-oxodG. Cancer Res 2020 09;80(17):3530-3541
Rudd SG et al
2020/01/01
PubMed
27 Zhang L et al. OGG1 co-inhibition antagonizes the tumor-inhibitory effects of targeting MTH1. Redox Biol 2021 04;40:101848
Zhang L et al
2021/01/01
PubMed
28 Karsten S et al. MTH1 as a target to alleviate T cell driven diseases by selective suppression of activated T cells. Cell Death Differ 2021 Aug;
Karsten S et al
2021/01/01
Species: Human, Applications: WB PubMed
  • No.: 1
  • 文献情報:
    Takeshita F et al. Mechanistic approach of contrasting modifying effects of caffeine on carcinogenesis in the rat colon and mammary gland induced with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. Cancer Lett. 2003 May;194(1):25-35
    Takeshita F et al
    2003/01/01
  • 備考:
    western, immunohistochemistry-paraffin, rat
  • 参照:
    PubMed
  • No.: 2
  • 文献情報:
    Kennedy CH et al. Expression of human MutT homologue (hMTH1) protein in primary non-small-cell lung carcinomas and histologically normal surrounding tissue. Free Radic. Biol. Med. 2003 Jun;34(11):1447-57
    Kennedy CH et al
    2003/01/01
  • 備考:
    western and Immunohistochemistry-frozen, human
  • 参照:
    PubMed
  • No.: 3
  • 文献情報:
    Rai P et al. Enhanced elimination of oxidized guanine nucleotides inhibits oncogenic RAS-induced DNA damage and premature senescence. Oncogene 2011 Mar;30(12):1489-96
    Rai P et al
    2011/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 4
  • 文献情報:
    Rai P et al. Continuous elimination of oxidized nucleotides is necessary to prevent rapid onset of cellular senescence. Proc. Natl. Acad. Sci. U.S.A. 2009 Jan;106(1):169-74
    Rai P et al
    2009/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 5
  • 文献情報:
    Chang IY et al. Acute responses of DNA repair proteins and StarD6 in rat hippocampus after domoic acid-induced excitotoxicity. Acta Histochem. 2012 Aug;
    Chang IY et al
    2012/01/01
  • 備考:
    Species: Mouse, Applications: WB
  • 参照:
    PubMed
  • No.: 6
  • 文献情報:
    Sheng Z et al. 8-Oxoguanine causes neurodegeneration during MUTYH-mediated DNA base excision repair. J. Clin. Invest. 2012 Dec;122(12):4344-61
    Sheng Z et al
    2012/01/01
  • 備考:
    Species: Mouse, Applications: IHC, ICC/IF
  • 参照:
    PubMed
  • No.: 7
  • 文献情報:
    Patel A et al. MutT Homolog 1 (MTH1) maintains multiple KRAS-driven pro-malignant pathways. Oncogene 2014 Jul;
    Patel A et al
    2014/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 8
  • 文献情報:
    Huber KV et al. Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy. Nature 2014 Apr;508(7495):222-7
    Huber KV et al
    2014/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 9
  • 文献情報:
    Carter M et al. Crystal structure, biochemical and cellular activities demonstrate separate functions of MTH1 and MTH2. Nat Commun 2015;6:7871
    Carter M et al
    2015/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 10
  • 文献情報:
    Bruel L et al. α-Galactosidase/sucrose kinase (AgaSK), a novel bifunctional enzyme from the human microbiome coupling galactosidase and kinase activities. J. Biol. Chem. 2011 Nov;286(47):40814-23
    Bruel L et al
    2011/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 11
  • 文献情報:
    Giribaldi MG et al. MTH1 expression is required for effective transformation by oncogenic HRAS. Oncotarget 2015 May;6(13):11519-29
    Giribaldi MG et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 12
  • 文献情報:
    Huber KV et al. Proteome-wide drug and metabolite interaction mapping by thermal-stability profiling. Nat. Methods 2015 Nov;12(11):1055-7
    Huber KV et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 13
  • 文献情報:
    Hashiguchi K et al. The roles of human MTH1, MTH2 and MTH3 proteins in maintaining genome stability under oxidative stress. Mutat. Res. 2018 Mar;808:10-19
    Hashiguchi K et al
    2018/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 14
  • 文献情報:
    Eshtad S et al. hMYH and hMTH1 cooperate for survival in mismatch repair defective T-cell acute lymphoblastic leukemia. Oncogenesis 2016 Dec;5(12):e275
    Eshtad S et al
    2016/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 15
  • 文献情報:
    Bonora M et al. Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition. Oncogene 2015 Mar;34(12):1608
    Bonora M et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 16
  • 文献情報:
    Fan J et al. Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway. J. Lipid Res. 2018 May;59(5):830-842
    Fan J et al
    2018/01/01
  • 備考:
    WB
  • 参照:
    PubMed
  • No.: 17
  • 文献情報:
    Zhou H et al. Human MutT homologue 1 mRNA overexpression correlates to poor response of multiple myeloma. Int. J. Hematol. 2017 Mar;105(3):318-325
    Zhou H et al
    2017/01/01
  • 備考:
    Species: Human, Applications:
  • 参照:
    PubMed
  • No.: 18
  • 文献情報:
    Page BDG et al. Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells. Nat Commun 2018 01;9(1):250
    Page BDG et al
    2018/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed
  • No.: 19
  • 文献情報:
    Zou X et al. Validating the concept of mutational signatures with isogenic cell models. Nat Commun 2018 May;9(1):1744
    Zou X et al
    2018/01/01
  • 備考:
    WB
  • 参照:
    PubMed
  • No.: 20
  • 文献情報:
    Bialkowski K et al. A profile of 8-oxo-dGTPase activities in the NCI-60 human cancer panel: Meta-analytic insight into the regulation and role of MTH1 (NUDT1) gene expression in carcinogenesis. Free Radic Biol Med 2020 02;148:1-21
    Bialkowski K et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 21
  • 文献情報:
    Godoy PRDV et al. Targeting NRF2, Regulator of Antioxidant System, to Sensitize Glioblastoma Neurosphere Cells to Radiation-Induced Oxidative Stress. Oxid Med Cell Longev 2020;2020:2534643
    Godoy PRDV et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 22
  • 文献情報:
    Wang J et al. The Epstein-Barr virus nuclear antigen-1 upregulates the cellular antioxidant defense to enable B-cell growth transformation and immortalization. Oncogene 2020 01;39(3):603-616
    Wang J et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 23
  • 文献情報:
    McPherson LA et al. Increased MTH1-specific 8-oxodGTPase activity is a hallmark of cancer in colon, lung and pancreatic tissue. DNA Repair (Amst) 2019 11;83:102644
    McPherson LA et al
    2019/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 24
  • 文献情報:
    Arczewska KD et al. hMTH1 and GPX1 expression in human thyroid tissue is interrelated to prevent oxidative DNA damage. DNA Repair (Amst) 2020 11;95:102954
    Arczewska KD et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 25
  • 文献情報:
    Moukengue B et al. TH1579, MTH1 inhibitor, delays tumour growth and inhibits metastases development in osteosarcoma model. EBioMedicine 2020 Mar;53:102704
    Moukengue B et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 26
  • 文献情報:
    Rudd SG et al. MTH1 Inhibitor TH588 Disturbs Mitotic Progression and Induces Mitosis-Dependent Accumulation of Genomic 8-oxodG. Cancer Res 2020 09;80(17):3530-3541
    Rudd SG et al
    2020/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 27
  • 文献情報:
    Zhang L et al. OGG1 co-inhibition antagonizes the tumor-inhibitory effects of targeting MTH1. Redox Biol 2021 04;40:101848
    Zhang L et al
    2021/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 28
  • 文献情報:
    Karsten S et al. MTH1 as a target to alleviate T cell driven diseases by selective suppression of activated T cells. Cell Death Differ 2021 Aug;
    Karsten S et al
    2021/01/01
  • 備考:
    Species: Human, Applications: WB
  • 参照:
    PubMed