Anti-APE1, Rabbit-Poly <Anti-Apurinic/Apyrimidinic Endonuclease, Rabbit-Poly>

データシート

• 商品コード：NB100-101
• メーカー：NOV
• 包装：100μl
• 価格： ¥96,000
• 在庫：無(未発注)

マイリストに追加 マイリストに追加済

• No.： 1
• 文献情報：
  Morita-Fujimura Y et al. Early decrease in apurinic/apyrimidinic endonuclease is followed by DNA fragmentation after cold injury-induced brain trauma in mice. Neuroscience 1999;93(4):1465-73
  Morita-Fujimura Y et al
  1999/01/01
  
• 備考：
  Western Blot, Immunohistochemsitry, Mouse
• 参照：
  

• No.： 2
• 文献情報：
  Fujimura M et al. Copper-zinc superoxide dismutase prevents the early decrease of apurinic/apyrimidinic endonuclease and subsequent DNA fragmentation after transient focal cerebral ischemia in mice. Stroke 1999 Nov;30(11):2408-15
  Fujimura M et al
  1999/01/01
  
• 備考：
  Western Blot, Immunohistochemsitry, Mouse
• 参照：
  

• No.： 3
• 文献情報：
  Chang YY et al. Neuroprotective effects of an antioxidant in cortical cerebral ischemia: prevention of early reduction of the apurinic/apyrimidinic endonuclease DNA repair enzyme. Neurosci. Lett. 1999 Dec;277(1):61-4
  Chang YY et al
  1999/01/01
  
• 備考：
  Immunohistochemistry, Mouse
• 参照：
  

• No.： 4
• 文献情報：
  Tell G et al. Mitochondrial localization of APE/Ref-1 in thyroid cells. Mutat. Res. 2001 Mar;485(2):143-52
  Tell G et al
  2001/01/01
  
• 備考：
  Western Blot, Immunohistochemistry, Human
• 参照：
  

• No.： 5
• 文献情報：
  Cappelli E et al. Rates of base excision repair are not solely dependent on levels of initiating enzymes. Carcinogenesis 2001 Mar;22(3):387-93
  Cappelli E et al
  2001/01/01
  
• 備考：
  Western Blot, Human
• 参照：
  

• No.： 6
• 文献情報：
  Bobola MS et al. Apurinic/apyrimidinic endonuclease activity is elevated in human adult gliomas. Clin. Cancer Res. 2001 Nov;7(11):3510-8
  Bobola MS et al
  2001/01/01
  
• 備考：
  Western Blot, Human
• 参照：
  

• No.： 7
• 文献情報：
  Silber JR et al. The apurinic/apyrimidinic endonuclease activity of Ape1/Ref-1 contributes to human glioma cell resistance to alkylating agents and is elevated by oxidative stress. Clin. Cancer Res. 2002 Sep;8(9):3008-18
  Silber JR et al
  2002/01/01
  
• 備考：
  Western Blot, Human
• 参照：
  

• No.： 8
• 文献情報：
  Freitas S et al. Studies of apurinic/apyrimidinic endonuclease/ref-1 expression in epithelial ovarian cancer: correlations with tumor progression and platinum resistance. Clin. Cancer Res. 2003 Oct;9(13):4689-94
  Freitas S et al
  2003/01/01
  
• 備考：
  Western Blot, Human
• 参照：
  

• No.： 9
• 文献情報：
  Takahashi G et al. MCI-186 reduces oxidative cellular damage and increases DNA repair function in the rabbit spinal cord after transient ischemia. Ann. Thorac. Surg. 2004 Aug;78(2):602-7
  Takahashi G et al
  2004/01/01
  
• 備考：
  
• 参照：
  

• No.： 10
• 文献情報：
  Akbari M et al. Repair of U/G and U/A in DNA by UNG2-associated repair complexes takes place predominantly by short-patch repair both in proliferating and growth-arrested cells. Nucleic Acids Res. 2004;32(18):5486-98
  Akbari M et al
  2004/01/01
  
• 備考：
  Western Blot, Bovine
• 参照：
  

• No.： 11
• 文献情報：
  Lam W et al. Apurinic/apyrimidinic endonuclease-1 protein level is associated with the cytotoxicity of L-configuration deoxycytidine analogs (troxacitabine and beta-L-2&#39;,3&#39;-dideoxy-2&#39;,3&#39;-didehydro-5-fluorocytidine) but not D-configuration deoxycytidine an
  Lam W et al
  2006/01/01
  
• 備考：
  
• 参照：
  

• No.： 12
• 文献情報：
  Cabelof DC et al. Age-related loss of the DNA repair response following exposure to oxidative stress. J. Gerontol. A Biol. Sci. Med. Sci. 2006 May;61(5):427-34
  Cabelof DC et al
  2006/01/01
  
• 備考：
  
• 参照：
  

• No.： 13
• 文献情報：
  Zou GM et al. Ape1 regulates hematopoietic differentiation of embryonic stem cells through its redox functional domain. Blood 2007 Mar;109(5):1917-22
  Zou GM et al
  2007/01/01
  
• 備考：
  
• 参照：
  

• No.： 14
• 文献情報：
  O&#39;Hara AM et al. Interleukin-8 induction by Helicobacter pylori in gastric epithelial cells is dependent on apurinic/apyrimidinic endonuclease-1/redox factor-1. J. Immunol. 2006 Dec;177(11):7990-9
  O&#39;Hara AM et al
  2006/01/01
  
• 備考：
  
• 参照：
  

• No.： 15
• 文献情報：
  Briegert M et al. Human monocytes, but not dendritic cells derived from them, are defective in base excision repair and hypersensitive to methylating agents. Cancer Res. 2007 Jan;67(1):26-31
  Briegert M et al
  2007/01/01
  
• 備考：
  
• 参照：
  

• No.： 16
• 文献情報：
  Yang B et al. Virion-associated uracil DNA glycosylase-2 and apurinic/apyrimidinic endonuclease are involved in the degradation of APOBEC3G-edited nascent HIV-1 DNA. J. Biol. Chem. 2007 Apr;282(16):11667-75
  Yang B et al
  2007/01/01
  
• 備考：
  
• 参照：
  

• No.： 17
• 文献情報：
  Raffoul JJ et al. Down-regulation of apurinic/apyrimidinic endonuclease 1/redox factor-1 expression by soy isoflavones enhances prostate cancer radiotherapy in vitro and in vivo. Cancer Res. 2007 Mar;67(5):2141-9
  Raffoul JJ et al
  2007/01/01
  
• 備考：
  
• 参照：
  

• No.： 18
• 文献情報：
  Kawase M et al. Reduction of apurinic/apyrimidinic endonuclease expression after transient global cerebral ischemia in rats: implication of the failure of DNA repair in neuronal apoptosis. Stroke 1999 Feb;30(2):441-8; discussion 449
  Kawase M et al
  1999/01/01
  
• 備考：
  Western Blot, Immunohistochemsitry, Human
• 参照：
  

• No.： 19
• 文献情報：
  Juliana FM et al. Apurinic/apyrimidinic endonuclease1/redox factor-1 (Ape1/Ref-1) is essential for IL-21-induced signal transduction through ERK1/2 pathway. Biochem. Biophys. Res. Commun. 2012 Apr;420(3):628-34
  Juliana FM et al
  2012/01/01
  
• 備考：
  
• 参照：
  

• No.： 20
• 文献情報：
  Yang Z et al. Nitric oxide initiates progression of human melanoma via a feedback loop mediated by apurinic/apyrimidinic endonuclease-1/redox factor-1, which is inhibited by resveratrol. Mol. Cancer Ther. 2008 Dec;7(12):3751-60
  Yang Z et al
  2008/01/01
  
• 備考：
  
• 参照：
  

• No.： 21
• 文献情報：
  Lam W et al. Effect of hypoxia on the expression of phosphoglycerate kinase and antitumor activity of troxacitabine and gemcitabine in non-small cell lung carcinoma. Mol. Cancer Ther. 2009 Feb;8(2):415-23
  Lam W et al
  2009/01/01
  
• 備考：
  
• 参照：
  

• No.： 22
• 文献情報：
  Yan T et al. Differential cellular responses to prolonged LDR-IR in MLH1-proficient and MLH1-deficient colorectal cancer HCT116 cells. Clin. Cancer Res. 2009 Nov;15(22):6912-20
  Yan T et al
  2009/01/01
  
• 備考：
  
• 参照：
  

• No.： 23
• 文献情報：
  O&#39;reilly MA et al. p21(Cip1/WAF1/Sdi1) does not affect expression of base excision DNA repair enzymes during chronic oxidative stress. Antioxid. Redox Signal. ;7(5-6):719-25
  O&#39;reilly MA et al
  
• 備考：
  
• 参照：
  

• No.： 24
• 文献情報：
  Vasko MR et al. The repair function of the multifunctional DNA repair/redox protein APE1 is neuroprotective after ionizing radiation. DNA Repair (Amst.) 2011 Sep;10(9):942-52
  Vasko MR et al
  2011/01/01
  
• 備考：
  
• 参照：
  

• No.： 25
• 文献情報：
  Mohammed MZ et al. Development and evaluation of human AP endonuclease inhibitors in melanoma and glioma cell lines. Br. J. Cancer 2011 Feb;104(4):653-63
  Mohammed MZ et al
  2011/01/01
  
• 備考：
  
• 参照：
  

• No.： 26
• 文献情報：
  Wang S et al. Cellular NAD replenishment confers marked neuroprotection against ischemic cell death: role of enhanced DNA repair. Stroke 2008 Sep;39(9):2587-95
  Wang S et al
  2008/01/01
  
• 備考：
  
• 参照：
  

• No.： 27
• 文献情報：
  La Maestra S et al. Cigarette smoke induces DNA damage and alters base-excision repair and tau levels in the brain of neonatal mice. Toxicol. Sci. 2011 Oct;123(2):471-9
  La Maestra S et al
  2011/01/01
  
• 備考：
  
• 参照：
  

• No.： 28
• 文献情報：
  Kim YJ et al. S-glutathionylation of cysteine 99 in the APE1 protein impairs abasic endonuclease activity. J. Mol. Biol. 2011 Dec;414(3):313-26
  Kim YJ et al
  2011/01/01
  
• 備考：
  
• 参照：
  

• No.： 29
• 文献情報：
  Lee HM et al. Apurinic/apyrimidinic endonuclease 1 is a key modulator of keratinocyte inflammatory responses. J. Immunol. 2009 Nov;183(10):6839-48
  Lee HM et al
  2009/01/01
  
• 備考：
  
• 参照：
  

• No.： 30
• 文献情報：
  Taverna P et al. Methoxyamine potentiates DNA single strand breaks and double strand breaks induced by temozolomide in colon cancer cells. Mutat. Res. 2001 May;485(4):269-81
  Taverna P et al
  2001/01/01
  
• 備考：
  
• 参照：
  

• No.： 31
• 文献情報：
  Szczesny B et al. Long patch base excision repair in mammalian mitochondrial genomes. J. Biol. Chem. 2008 Sep;283(39):26349-56
  Szczesny B et al
  2008/01/01
  
• 備考：
  
• 参照：
  

• No.： 32
• 文献情報：
  Kelley MR et al. Redox regulation of the DNA repair function of the human AP endonuclease Ape1/ref-1. Antioxid. Redox Signal. 2001 Aug;3(4):671-83
  Kelley MR et al
  2001/01/01
  
• 備考：
  
• 参照：
  

• No.： 33
• 文献情報：
  Fishel ML et al. Impact of APE1/Ref-1 redox inhibition on pancreatic tumor growth. Mol. Cancer Ther. 2011 Sep;10(9):1698-708
  Fishel ML et al
  2011/01/01
  
• 備考：
  Applications: WB, Species: Human
• 参照：
  

• No.： 34
• 文献情報：
  Lee JW et al. Expression Pattern of Apurinic/Apyrimidinic Endonuclease in Sinonasal Squamous Cell Carcinoma. Otolaryngol Head Neck Surg 2012 May;
  Lee JW et al
  2012/01/01
  
• 備考：
  Applications: IHC, Species: Human
• 参照：
  

• No.： 35
• 文献情報：
  Shaked H et al. Chronic epithelial NF-&#x3BA;B activation accelerates APC loss and intestinal tumor initiation through iNOS up-regulation. Proc. Natl. Acad. Sci. U.S.A. 2012 Aug;109(35):14007-12
  Shaked H et al
  2012/01/01
  
• 備考：
  Species: Mouse, Applications: IHC
• 参照：
  

• No.： 36
• 文献情報：
  Kadekaro AL et al. Alpha-melanocyte-stimulating hormone suppresses oxidative stress through a p53-mediated signaling pathway in human melanocytes. Mol. Cancer Res. 2012 Jun;10(6):778-86
  Kadekaro AL et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 37
• 文献情報：
  McManus F et al. APEX1 regulation of aldosterone synthase gene transcription is disrupted by a common polymorphism in humans. Circ. Res. 2012 Jul;111(2):212-9
  McManus F et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: ChIP
• 参照：
  

• No.： 38
• 文献情報：
  Sultana R et al. Synthetic lethal targeting of DNA double-strand break repair deficient cells by human apurinic/apyrimidinic endonuclease inhibitors. Int. J. Cancer 2012 Nov;131(10):2433-44
  Sultana R et al
  2012/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 39
• 文献情報：
  Cardoso AA et al. APE1/Ref-1 Regulates STAT3 Transcriptional Activity and APE1/Ref-1-STAT3 Dual-Targeting Effectively Inhibits Pancreatic Cancer Cell Survival. PLoS ONE 2012;7(10):e47462
  Cardoso AA et al
  2012/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 40
• 文献情報：
  Kim HL et al. A Novel Role for Gadd45&#x3B1; in Base Excision Repair: Modulation of APE1 Activity by the Direct Interaction of Gadd45&#x3B1; with PCNA. Biochem. Biophys. Res. Commun. 2013 Feb;
  Kim HL et al
  2013/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 41
• 文献情報：
  Chu TH et al. Down-regulation of apurinic/apyrimidinic endonuclease 1 (APE1) in spinal motor neurons under oxidative stress. Neuropathol. Appl. Neurobiol. 2013 Jul;
  Chu TH et al
  2013/01/01
  
• 備考：
  Species: Rat, Mouse, Applications: WB, IHC
• 参照：
  

• No.： 42
• 文献情報：
  Abdel-Fatah TM et al. Clinicopathological significance of human apurinic/apyrimidinic endonuclease 1 (APE1) expression in oestrogen-receptor-positive breast cancer. Breast Cancer Res. Treat. 2014 Feb;143(3):411-21
  Abdel-Fatah TM et al
  2014/01/01
  
• 備考：
  
• 参照：
  

• No.： 43
• 文献情報：
  Alagoz M et al. TDP1 deficiency sensitizes human cells to base damage via distinct topoisomerase I and PARP mechanisms with potential applications for cancer therapy. Nucleic Acids Res. 2014 Mar;42(5):3089-103
  Alagoz M et al
  2014/01/01
  
• 備考：
  
• 参照：
  

• No.： 44
• 文献情報：
  Das D et al. 1,3-Bis(2-chloroethyl)-1-nitrosourea enhances the inhibitory effect of Resveratrol on 5-fluorouracil sensitive/resistant colon cancer cells. World J. Gastroenterol. 2013 Nov;19(42):7374-88
  Das D et al
  2013/01/01
  
• 備考：
  
• 参照：
  

• No.： 45
• 文献情報：
  Abdel-Fatah TM et al. Is there a role for base excision repair in estrogen/estrogen receptor-driven breast cancers? Antioxid. Redox Signal. 2014 Dec;21(16):2262-8
  Abdel-Fatah TM et al
  2014/01/01
  
• 備考：
  Species: Human, Applications: IHC-P
• 参照：
  

• No.： 46
• 文献情報：
  Das D et al. 5-Fluorouracil mediated anti-cancer activity in colon cancer cells is through the induction of Adenomatous Polyposis Coli: Implication of the long-patch base excision repair pathway. DNA Repair (Amst.) 2014 Nov;24C:15-25
  Das D et al
  2014/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 47
• 文献情報：
  Liu GD et al. Genistein alleviates radiation-induced pneumonitis by depressing Ape1/Ref-1 expression to down-regulate inflammatory cytokines. Cell Biochem. Biophys. 2014 Jul;69(3):725-33
  Liu GD et al
  2014/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 48
• 文献情報：
  Iglesias-Ara A et al. E2F1 and E2F2 prevent replicative stress and subsequent p53-dependent organ involution. Cell Death Differ. 2015 Feb;
  Iglesias-Ara A et al
  2015/01/01
  
• 備考：
  Species: Mouse, Applications: WB
• 参照：
  

• No.： 49
• 文献情報：
  Akbari M et al. Different organization of base excision repair of uracil in DNA in nuclei and mitochondria and selective upregulation of mitochondrial uracil-DNA glycosylase after oxidative stress. Neuroscience 2007 Apr;145(4):1201-12
  Akbari M et al
  2007/01/01
  
• 備考：
  
• 参照：
  

• No.： 50
• 文献情報：
  Vrouwe MG et al. UV-induced photolesions elicit ATR-kinase-dependent signaling in non-cycling cells through nucleotide excision repair-dependent and -independent pathways. J. Cell. Sci. 2011 Feb;124(Pt 3):435-46
  Vrouwe MG et al
  2011/01/01
  
• 備考：
  Species: Human
• 参照：
  

• No.： 51
• 文献情報：
  Al-Attar A et al. Human apurinic/apyrimidinic endonuclease (APE1) is a prognostic factor in ovarian, gastro-oesophageal and pancreatico-biliary cancers. Br. J. Cancer 2010 Feb;102(4):704-9
  Al-Attar A et al
  2010/01/01
  
• 備考：
  Species: Human
• 参照：
  

• No.： 52
• 文献情報：
  Qui単ones JL et al. Enzyme mechanism-based, oxidative DNA-protein cross-links formed with DNA polymerase &#x3B2; in vivo. Proc. Natl. Acad. Sci. U.S.A. 2015 Jul;112(28):8602-7
  Qui単ones JL et al
  2015/01/01
  
• 備考：
  
• 参照：
  

• No.： 53
• 文献情報：
  Nassour H et al. Peroxiredoxin 1 interacts with and blocks the redox factor APE1 from activating interleukin-8 expression. Sci Rep 2016;6:29389
  Nassour H et al
  2016/01/01
  
• 備考：
  
• 参照：
  

• No.： 54
• 文献情報：
  Poletto M et al. p53 coordinates base excision repair to prevent genomic instability. Nucleic Acids Res. 2016 Apr;44(7):3165-75
  Poletto M et al
  2016/01/01
  
• 備考：
  
• 参照：
  

• No.： 55
• 文献情報：
  Fehrenbacher JC et al. DNA damage mediates changes in neuronal sensitivity induced by the inflammatory mediators, MCP-1 and LPS, and can be reversed by enhancing the DNA repair function of APE1. Neuroscience 2017 Dec;366:23-35
  Fehrenbacher JC et al
  2017/01/01
  
• 備考：
  Applications: WB
• 参照：
  

• No.： 56
• 文献情報：
  Sandomenico A et al. Monoclonal antibodies against pools of mono- and polyacetylated peptides selectively recognize acetylated lysines within the context of the original antigen. MAbs ;8(8):1575-1589
  Sandomenico A et al
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 57
• 文献情報：
  Logsdon DP et al. Regulation of HIF1&#x3B1; under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual Targeting in Patient-Derived 3D Pancreatic Cancer Models. Mol. Cancer Ther. 2016 Nov;15(11):2722-2732
  Logsdon DP et al
  2016/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 58
• 文献情報：
  Logsdon DP et al. Blocking HIF signaling via novel inhibitors of CA9 and APE1/Ref-1 dramatically affects pancreatic cancer cell survival. Sci Rep 2018 Sep;8(1):13759
  Logsdon DP et al
  2018/01/01
  
• 備考：
  Species: Human, Applications: WB
• 参照：
  

• No.： 59
• 文献情報：
  Sanchez JR et al. Increased human AP endonuclease 1 level confers protection against the paternal age effect in mice. Mutat. Res. 2015 Sep;779:124-33
  Sanchez JR et al
  2015/01/01
  
• 備考：
  
• 参照：
  

• No.： 60
• 文献情報：
  Qui単ones JL et al. Oxidative DNA-protein crosslinks formed in mammalian cells by abasic site lyases involved in DNA repair. DNA Repair (Amst) 2020 03;87:102773
  Qui単ones JL et al
  2020/01/01
  
• 備考：
  
• 参照：