価格表

在庫・価格 : 2024年05月04日 13時40分 現在

商品名 商品コード メーカー 包装 価格 在庫 リスト
siRNA Transfection Reagent Kit, GeneSilencer (5×200 reactions)
データシート※最新のデータシートでない場合があります
T505750 GTSジェンランティス
Genlantis
1 kit 本製品は取扱中止になりました 追加

在庫・価格 : 2024年05月04日 13時40分 現在

siRNA Transfection Reagent Kit, GeneSilencer (5×200 reactions)

  • 商品コード:T505750
  • メーカー:GTS
  • 包装:1kit
  • 本製品は取扱中止になりました
使用文献
No. 文献情報 備考 参照
1 de Barry, J., Janoshazi, A., Luc Dupont, J., Procksch, O., Chasserot-Golaz, S., Jeromin, A. and Vitale, N. (2006) Functional Implication of Neuronal Calcium Sensor-1 and Phosphoinositol 4-Kinase-?? Interaction in Regulated Exocytosis of PC12 Cells. J. Bio

Cell Line: PC-12, Cell Type: Pheochromocytoma, Source: Rat PubMed
2 Amaral, M.D. and Pozzo-Miller, L. (2007) TRPC3 Channels Are Necessary for Brain-Derived Neurotrophic Factor to Activate a Nonselective Cationic Current and to Induce Dendritic Spine Formation. J. Neurosci. 27(19): p. 5179-5189.

Cell Line: Primary, Cell Type: Hippocampal Neurons, Source: Rat PubMed
3 Khundmiri, S.J., Dean, W.L., McLeish, K.R. and Lederer, E.D. (2005) Parathyroid Hormone-mediated Regulation of Na+-K+-ATPase Requires ERK-dependent Translocation of Protein Kinase C{alpha}. J. Biol. Chem. 280(10): p. 8705-8713.

Cell Line: OK, Cell Type: Kidney, Source: Opossum PubMed
4 Aleyasin, H., Cregan, S.P., Iyirhiaro, G., OHare, M.J., Callaghan, S.M., Slack, R.S. and Park, D.S. (2004) Nuclear Factor-B Modulates the p53 Response in Neurons Exposed to DNA Damage. J. Neurosci. 24 (12): 2963-2973.

Cell Line: Primary, Cell Type: Cortical Neurons, Source: Mouse PubMed
5 Khundmiri, S.J., Ameen, M., Delamere, N.A. and Lederer, E.D. (2008) PTH-mediated regulation of Na+ -K+ -ATPase requires Src kinase-dependent ERK Phosphorylation. Am J Physiol Renal Physiol. 295(2): F426-F437.

Cell Line: OK, Cell Type: Kidney, Source: Opossum PubMed
6 Aarts, M., Lihara, K., Wei, W-L, Xiong, Z-G, Arundine, M., Cerwinski, W., MacDonald, J.F., Tymianski, M. (2003) A Key Role for TRPM7 Channels in Anoxic Neuronal Death. Cell 115: 863.

Cell Line: Primary, Cell Type: Cortical Neurons, Source: Mouse PubMed
7 Asmis, R., Wang, Y., Xu, L., Kisgati, M., Begley, J.G. and?Mieyal, J.J. (2005) A novel thiol oxidation-based mechanism for adriamycin-induced cell injury in human macrophages. FASEB J. published 13 September 2005, 10.1096/fj.04-2991fje.

Cell Line: Primary, Cell Type: Macrophage, Source: Human PubMed
8 Birukova, A.A., Chatchavalvanich, S., Rios, A., Kawkitinarong, K., Garcia, J.G.N. and Birukov, K.G. (2006) Differential Regulation of Pulmonary Endothelial Monolayer Integrity by Varying Degrees of Cyclic Stretch. Am. J. Pathol. 168: 1749 - 1761.

Cell Line: Primary, Cell Type: Pulmonary Artery Endothelium, Source: Human PubMed
9 Chung, J-S, Sato, K., Dougherty, I.I., Cruz, Jr., P.D. and Ariizumi, K. (2007) DC-HIL is a negative regulator of T lymphocyte activation. Blood. 109(10): p. 4320-4327.

Cell Line: Primary, Cell Type: Dendritic Cells (Bone Marrow), Source: Mouse PubMed
10 Cui, H., Hayashi, A., Sun, H-S, Belmares, M.P., Cobey, C., Phan, T., Schweizer, J., Salter, M.W., Wang, Y.T., Tasker, R.A., Garman, D., Rabinowitz, J., Lu, P.S. and Tymianski, M. (2007) PDZ Protein Interactions Underlying NMDA Receptor-Mediated Excitotoxi

Cell Line: Primary, Cell Type: Cortical Neurons, Source: Mouse PubMed
11 Hayashi, H., Campenot, R.B., Vance, D.E. and Vance, J.E. (2007) Apolipoprotein E-Containing Lipoproteins Protect Neurons from Apoptosis via a Signaling Pathway Involving Low-Density Lipoprotein Receptor-Related Protein-1. J. Neurosci. 27(8): 1933-1941.

Cell Line: Primary, Cell Type: Retinal Ganglion, Source: Rat PubMed
12 Haruhisa Higuchi, Toshihide Yamashita, Hideki Yoshikawa, and Masaya Tohyama (2003) Functional inhibition of the p75 receptor using a small interfering RNA. Biochem. & Biophys. Res. Comm. 301: 804809.

Cell Line: Primary, Cell Type: Dorsal Root Ganglion Neurons, Source: Mouse PubMed
13 Ge, L., Shenoy, S.K., Lefkowitz, R.J. and DeFea, K.A. (2004) Constitutive protease-activated-receptor-2 mediated migration of MDA MB-231 breast cancer cells requires both beta-arrestin-1 and 2. J. Biol. Chem. 279(53): p. 55419-55424.

Cell Line: MDA MB-231, Cell Type: Breast Cancer, Source: Human PubMed
14 Dandapat, A., Hu, C., Sun, L. and Mehta, J.L. (2007) Small Concentrations of oxLDL Induce Capillary Tube Formation From Endothelial Cells via LOX-1 Dependent Redox-Sensitive Pathway. Arterioscler Thromb Vasc Biol.

Cell Line: Primary, Cell Type: Coronary Artery Endothelial, Source: Human HCAEC PubMed
15 de Beer, M.C., Zhao, Z., Webb, N.R., van der Westhuyzen, D.R. and de Villiers, W.J.S. (2003) Lack of a direct role for macrosialin in oxidized LDL metabolism J. Lipid Res. 44: 674 - 685.

Cell Line: Primary, Cell Type: Peritoneal Macrophage, Source: Mouse PubMed
16 Burkhalter, J., Fiumelli, H., Erickson, J.D. and Martin, J-L. (2007) A critical role for system a amino acid transport in the regulation of dendritic development by BDNF. J Biol Chem 282: 5152 - 5159.

Cell Line: Primary, Cell Type: Cortical Neurons, Source: Mouse PubMed
17 Zoudilova, M., Kumar, P., Ge, L., Wang, P., Bokoch, G. M. and DeFea, K. A. (2007) ??-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2. J. Biol. Chem. 282: 20634 - 20646.

Cell Line: MDA-MB-468, Cell Type: Breast Carcinoma, Source: Human PubMed
18 Park, S-Y., Kang, K-B., Thapa, N., Kim, S-Y., Lee, S-J. and Kim, I-S. (2008) Requirement of Adaptor Protein GULP during Stabilin-2-mediated Cell Corpse Engulfment. J. Biol. Chem. 283(16): 10593-10600.

Cell Line: L/Stab-2, Cell Type: Fibroblast, Source: Mouse PubMed
19 Takayama, K., Tsutsumi, S., Suzuki, T., Horie-Inoue, K., Ikeda, K., Kaneshiro, K. Fujimura, T., Kumagai, J., Urano, T., Sakaki, Y., Shirahige, K., Sasano, H., Takahashi, S., Kitamura, T., Ouchi, Y., Aburatani, H. and Inoue, S. (2009) Amyloid precursor pro

Cell Line: LNCaP, Cell Type: Prostate Cancer, Source: Human PubMed
20 Liu, X., Yao, M., Li, N., Wang, C., Zheng, Y. and Cao, X. (2008) CaMKII promotes TLR-triggered proinflammatory cytokine and type I interferon production by directly binding and activating TAK1 and IRF3 in macrophages. Blood. 112(13): 4961-4970.

Cell Line: RAW 264.7, Cell Type: Macrophage, Source: Mouse PubMed
21 Hengst, U. Cox, L.J., Macosko, E.Z. and Jaffrey, S.R. (2006) Functional and Selective RNA Interference in Developing Axons and Growth Cones. J. Neurosci. 26(21): 5727-5732.

Cell Line: Primary, Cell Type: Dorsal Root Ganglion, Source: Rat PubMed
22 Scott, M.G.H., Pierotti, V., Storez, H., Lindberg, E., Thuret, A., Muntaner, O., Labbe-Jullie, C., Pitcher, J.A. and Marullo, S. (2006) Cooperative Regulation of Extracellular Signal-Regulated Kinase Activation and Cell Shape Change by Filamin A and ??-Ar

Cell Line: M2, Cell Type: Melanoma, Source: Human PubMed
23 Pastorino, J.G. and Shulga, N. (2008) Tumor Necrosis Factor-{alpha} Can Provoke Cleavage and Activation of Sterol Regulatory Element-binding Protein in Ethanol-exposed Cells via a Caspase-dependent Pathway That Is Cholesterol Insensitive. J. Biol. Chem. 2

Cell Line: McA-RH 7777, Cell Type: Hepatoma, Source: Rat PubMed
24 Abboud-Jarrous, G., Atzmon, R., Peretz, T., Palermo, C., Gadea, B.B., Joyce, J.A.and Vlodavsky, I. (2008) Cathepsin L Is Responsible for Processing and Activation of Proheparanase through Multiple Cleavages of a Linker Segment. J. Biol. Chem. 283: 18167 -

Cell Line: MDA-MB-435, Cell Type: Melanoma, Source: Human PubMed
25 Nomachi, A., Nishita, M., Inaba, D., Enomoto, M., Hamasaki, M. and Minami, Y. (2008) Receptor Tyrosine Kinase Ror2 Mediates Wnt5a-induced Polarized Cell Migration by Activating c-Jun N-terminal Kinase via Actin-binding Protein Filamin A. J. Biol. Chem. 28

Cell Line: NIH-3T3, Cell Type: Fibroblast, Source: Mouse PubMed
26 Ichikawa, T., Horie-Inoue, K., Ikeda, K., Blumberg, B. and Inoue, S. (2007) Vitamin K2 induces phosphorylation of protein kinase A and expression of novel target genes in osteoblastic cells. J Mol Endocrinol 1 39 (4): 239.

Cell Line: MG63, Cell Type: Osteosarcoma, Source: Human PubMed
27 Nagasako, T., Sugiyama, T., Mizushima, T., Miura, Y., Kato, M. and Asaka, M. (2003) Up-regulated Smad5 Mediates Apoptosis of Gastric Epithelial Cells Induced by Helicobacter pylori Infection. J. Biol. Chem.: 278: 4821 - 4825.

Cell Line: MKN 28, Cell Type: Gastric Epithelium, Source: Human PubMed
28 Yang, X., Liu, L., Sternberg, D., Tang, L., Galinsky, I., DeAngelo, D. and Stone, R. (2005) The FLT3 Internal Tandem Duplication Mutation Prevents Apoptosis in Interleukin-3-Deprived BaF3 Cells Due to Protein Kinase A and Ribosomal S6 Kinase 1-Mediated BA

Cell Line: MV-4-11, Cell Type: Biophenotypic B Myelomonocytic Leukemia, Source: Human PubMed
29 Bertling, E., Hotulainen, P., Mattila, P.K., Matilainen, T., Salminen, M., and Lappalainen, P. (2004) Cyclase-associated-protein 1 (CAP1) promotes cofilin-induced actin dynamics in mammalian nonmuscle cells. Mol. Biol. Cell 15 (5): p. 2324-2334.

Cell Line: Neuro2a, Cell Type: Neuroblastoma, Source: Mouse PubMed
30 Hotulainen, P., Paunola, E., Vartiainen, M.K. and Lappalainen, P. (2005) Actin-depolymerizing Factor and Cofilin-1 Play Overlapping Roles in Promoting Rapid F-Actin Depolymerization in Mammalian Nonmuscle Cells. Mol. Biol. Cell. 16(2): p. 649-664.

Cell Line: NIH-3T3, Cell Type: Fibroblast, Source: Mouse PubMed
31 Ikeda, K., Ogawa, S., Tsukui, T., Horie-Inoue, K., Ouchi, Y., Kato, S., Muramatsu, M. and Inoue, S. (2004) Protein Phosphatase 5 Is a Negative Regulator of Estrogen Receptor-mediated Transcription. Mol. Endocrinol. 18(5): 1131-1143.

Cell Line: MCF-7, Cell Type: Breast Adenocarcinoma, Source: Human PubMed
32 Zheng, X., Chou, P.M., Mirkin, B.L. and Rebbaa, A. (2004) Senescence-initiated Reversal of Drug Resistance: Specific Role of Cathepsin L. Cancer Res. 64: 1773 - 1780.

Cell Line: Saos-2, Cell Type: Osteosarcoma, Source: Human PubMed
33 Xie, J., Chiang, L., Contreras, J., Wu, K., Garner, J.A., Medina-Kauwe, L. and Hamm-Alvarez, S.F. (2006) Novel Fiber-Dependent Entry Mechanism for Adenovirus Serotype 5 in Lacrimal Acini. J. Virol. 80(23): 11833 - 11851.

Cell Line: Primary, Cell Type: Lacrimal Gland Acinar Cells, Source: Rabbit PubMed
34 Yang, R., Cai, Z., Zhang, Y., Yutzy IV, W.H., Roby, K.F. and Roden, R.B.S. (2006) CD80 in Immune Suppression by Mouse Ovarian Carcinoma?Associated Gr-1+CD11b+ Myeloid Cells. Cancer Res 66 (13): 6807 - 6815.

Cell Line: Primary, Cell Type: Bone Marrow, Source: Mouse PubMed
35 Zheng, X., Koropatnick, J., Li, M., Zhang, X., Ling, F., Ren, X., Hao, X., Sun, H., Vladau, C., Franek, J.A., Feng, B., Urquhart, B.L., Zhong, R., Freeman, D.J., Garcia, B. and Min, W-P. (2006) Reinstalling Antitumor Immunity by Inhibiting Tumor-Derived I

Cell Line: Primary, Cell Type: Dendritic Cells, Source: Mouse PubMed
36 Zhuowei Li, Xhevahire Hyseni, Jacqueline D. Carter, Joleen M. Soukup, Lisa A. Dailey, and Yuh-Chin T. Huang (2006) Pollutant particles enhanced H2O2 production from NAD(P)H oxidase and mitochondria in human pulmonary artery endothelial cells. Am J Physiol

Cell Line: Primary, Cell Type: Pulmonary Artery Endothelium, Source: Human PubMed
37 de Beer, M.C., Zhao, Z., Webb, N.R., van der Westhuyzen, D.R. and de Villiers, W.J.S. (2003) Lack of a direct role for macrosialin in oxidized LDL metabolism. J. Lipid Res. 44: 674 - 685.

Cell Line: RAW 264.7, Cell Type: Macrophage, Source: Mouse PubMed
38 Ogushi, T., Takahashi, S., Takeuchi, T., Urano, T., Horie-Inoue, K., Kumagai, J., Kitamura, T., Ouchi, Y., Muramatsu, M. and Inoue, S. (2005) Estrogen Receptor-Binding Fragment-Associated Antigen 9 Is a Tumor-Promoting and Prognostic Factor for Renal Cell

Cell Line: Renca, Cell Type: Renal Cell Carcinoma, Source: Mouse PubMed
39 Rentsendorj, O., Mirzapoiazova, T., Adyshev, D., Servinsky, L.E., Renne, T., Verin, A.D. and Pearse, D.B. (2008) Role of vasodilator-stimulated phosphoprotein in cGMP-mediated protection of human pulmonary artery endothelial barrier function. Am J Physiol

Cell Line: Primary HPAEC, Cell Type: Pulmonary Artery Endothelium, Source: Human PubMed
40 Zheng, X., Chu, F., Chou, P.M., Gallati, C., Dier, U., Mirkin, B.L., Mousa, S.A. and Rebbaa, A. (2009) Cathepsin L inhibition suppresses drug resistance in vitro and in vivo: a putative mechanism. Am J Physiol Cell Physiol. 296(1): C65-C74.

Cell Line: SaOS2, Cell Type: Osteosarcoma, Source: Human PubMed
41 Ueno, T., Linder, S., Na, C-L, Rice, W.R., Johansson, J., and Weaver, T.E. (2004) Processing of Pulmonary Surfactant Protein B by Napsin and Cathepsin H. J. Biol. Chem. 279: 16178-16184.

Cell Line: Primary, Cell Type: Aveolar Type II Cells, Source: Mouse PubMed
42 Takahashi, A., Higashino, F., Aoyagi, M., Yoshida, K., Itoh, M., Kyo, S., Ohno, T., Taira, T., Ariga, H., Nakajima, K., Hatta, M., Kobayashi, M., Sano, H., Kohgo, T. and Shindoh, M., (2003) EWS/ETS Fusions Activate Telomerase in Ewings Tumors. Cancer Res

Cell Line: SCCH196, Cell Type: Sarcoma, Source: Human PubMed
43 Song, S.W., Fuller, G.N., Zheng, H. and Zhang, W. (2005) Inactivation of the Invasion Inhibitory Gene IIp45 by Alternative Splicing in Gliomas. Cancer Res. 65(9): p. 3562-3567.

Cell Line: SNB19, Cell Type: Glioblastoma, Source: Human PubMed
44 Zhu, S., Wang, W., Clarke, D.C. and Liu, X. (2007) Activation of Mps1 Promotes Transforming Growth Factor-??-independent Smad Signaling. J. Biol. Chem. 282(25): 18327-18338.

Cell Line: SW480, Cell Type: Colon Adenocarcinoma, Source: Human PubMed
45 Hotulainen P. and Lappalainen, P. (2006) Stress fibers are generated by two distinct actin assembly mechanisms in motile cells J. Cell Biol. 173(3): 383-394.

Cell Line: U20S, Cell Type: Osteosarcoma, Source: Human PubMed
46 Huang, B., Lei, Z., Zhang, G-M, Li, D., Song, C., Li, B., Liu, Y., Yuan, Y., Unkeless, J., Xiong, H. and Feng, Z-H (2008) SCF-mediated mast cell infiltration and activation exacerbate the inflammation and immunosuppression in tumor microenvironment. Blood

Cell Line: H22, Cell Type: Hepatoma, Source: Mouse PubMed
47 Chu, F.,Chou, P.M., Zheng, X., Mirkin, B.L. and Rebbaa, A.?(2005)?Control of Multidrug Resistance Gene mdr1 and Cancer Resistance to Chemotherapy by the Longevity Gene sirt1. Cancer Res.65 (22): p. 10183-10187.

Cell Line: SaOs2, Cell Type: Osteosarcoma, Source: Human PubMed
48 Ohyama, Y., Nifuji, A., Maeda, Y., Amagasa, T. and Noda, M. (2004) Spaciotemporal Association and Bone Morphogenetic Protein Regulation of Sclerostin and Osterix Expression during Embryonic Osteogenesis. Endocrinology. 145(10): p. 4685-4692.

Cell Line: Primary, Cell Type: Osteoblast, Source: Mouse PubMed
49 Hu, C., Dandapat, A., Sun, L., Khan, J.A., Liu, Y., Hermonat, P.L. and Mehta, J.L. (2008) Regulation of TGFbeta 1-mediated collagen formation by LOX-1: Studies based on forced over-expression of TGFbeta 1 in wild-type and LOX-1 knockout mice cardiac fibro

Cell Line: Primary, Cell Type: Cardiac Fibroblast, Source: Mouse PubMed
50 Juhaszova, M., Zorov, D.B., Kim, S-H, Pepe, S., Fu, O., Fishbein, K.W., Ziman, B.D., Wang, S., Ytrehus, K., Antos, C.L., Olson, E.N. and Sollott, S.J. (2004) Glycogen synthase kinase-3{beta} mediates convergence of protection signaling to inhibit the mito

Cell Line: Primary, Cell Type: Cardiac Myocytes (Neonatal), Source: Rat PubMed
51 Kolosova, I.A., Ma, S-F, Adyshev, D.M., Wang, P., Ohba, M., Natarajan, V., Garcia, J.G.N. and Verin, A.D. (2004) Role of CPI-17 in the regulation of endothelial cytoskeleton AJP: Lung. 287(5): L970.

Cell Line: Primary, Cell Type: Lung Microvascular Endothelial Cells, Source: Human PubMed
52 Lake, A.C. & Castellot, J.J. (2003) CCN5 modulates the antiproliferative effect of heparin and regulates cell motility in vascular smooth muscle cells. Cell Comm. & Signaling 1: 5.

Cell Line: Primary, Cell Type: Aortic Muscle Cells, Source: Rat PubMed
53 Li, M., Qian, H., Ichim, T.E., Ge, W-W, Popov, I.A., Rycerz, K., Neu, J., White, D., Zhong, R., Min, W-P. (2004) Induction of RNA Interference in Dendritic Cells. Immunologic Research 30 (2) 215-230.

Cell Line: Primary, Cell Type: Dendritic Cells, Source: Mouse PubMed
54 Li, M., Zhang, X., Zheng, X., Lian, D., Zhang, Z-X., Ge, W., Yang, J., Vladau, C., Suzuki, M., Chen, D., Zhong, R., Garcia, B., Jevnikar, A.M. and Min, W-P (2007) Immune Modulation and Tolerance Induction by RelB-Silenced Dendritic Cells through RNA Inter

Cell Line: Primary, Cell Type: Dendritic Cells, Source: Mouse PubMed
55 Wu, K.Y., Hengst, U., Cox, L.J., Macosko, E.Z., Jeromin, A., Urquhart, E.R., and Jaffrey, S.R. (2005) Local translation of RhoA regulates growth cone collapse. Nature 436: 1020-1024.

Cell Line: Primary, Cell Type: Dorsal Root Ganglion, Source: Rat PubMed
56 Numakawa, T., Nakayama, H., Suzuki, S., Kubo, T., Nara, F., Numakawa, Y., Yokomaku, D., Araki, T., Ishimoto, T., Ogura, A. and Taguchi, T. (2003) Nerve growth factor-induced glutamate release is via p75 receptor, ceramide and Ca2+ from ryanodine receptor

Cell Line: Primary, Cell Type: Cerebellar Neurons, Source: Rat PubMed
57 Wang, Y., Chen, T., Han, C., He, D., Liu, H., An, H., Cai, Z. and Cao, X. (2007) Lysosome-associated small Rab GTPase Rab7b negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Blood 110: 962 - 971.

Cell Line: Primary, Cell Type: Macrophage, Source: Mouse PubMed
58 Radu Stefanescu, Dustin Bassett, Rozbeh Modarresi, Francisco Santiago, Mohamad Fakruddin, and Jeffrey Laurence (2008) Synergistic interactions between interferon-{gamma} and TRAIL modulate c-FLIP in endothelial cells, mediating their lineage-specific sens

Cell Line: Primary, Cell Type: HMVEC, Source: Human PubMed
59 Ramabadran, R. S., Chancey, A., Vallejo, J.G., Barger, P.M., Sivasubramanian, N. and Mann, D.L. (2008) Targeted Gene Silencing of Tumor Necrosis Factor Attenuates the Negative Inotropic Effects of Lipopolysaccharide in Isolated Contracting Cardiac Myocyte

Cell Line: Primary, Cell Type: Cardiac Myocytes, Source: Feline PubMed
60 Samten, B., Howard, S.T., Weis, S.E., Wu, S., Shams, H., Townsend, J.C., Safi, H. and Barnes, P.F. (2005) Cyclic AMP Response Element-Binding Protein Positively Regulates Production of IFN-{gamma} by T Cells in Response to a Microbial Pathogen. J. Immunol

Cell Line: Primary, Cell Type: T-Cells (CD3+), Source: Human PubMed
61 Sato, S., Xu, J., Okuyama, S., Martinez, LB., Walsh, S.M, Jacobsen, M.T, Swan, R.J., Schlautman, J.D., Ciborowski, P. and Ikezu, T. (2008) Spatial learning impairment, enhanced CDK5/p35 activity, and downregulation of NMDA receptor expression in transgeni

Cell Line: Primary, Cell Type: Cortical Neurons, Source: Mouse PubMed
62 Smith, A.L., Ganesh, L., Leung, K., Jongstra-Bilen, J., Jongstra, J. and Nabel, G.J. (2007) Leukocyte-specific protein 1 interacts with DC-SIGN and mediates transport of HIV to the proteasome in dendritic cells. J. Exp. Med. 204(2): p. 421-430.

Cell Line: Primary, Cell Type: Dendritic Cells, Source: Human PubMed
63 Supnet, C., Grant, J., Kong, H., Westaway, D. and Mayne, M. (2006) Amyloid ??-(1-42) Increases Ryanodine Receptor-3 Expression and Function in TgCRND8 Mice. J. Biol. Chem. 281: 38440 - 38447.

Cell Line: Primary, Cell Type: Cortical Neurons, Source: Mouse PubMed
64 Higuchi, H., Yamashita, T., Yoshikawa, H. and Tohyama, M. (2003) Functional inhibition of the p75 receptor using a small interfering RNA. Biochem. & Biophys. Res. Comm. 301: 804809.

Cell Line: Primary, Cell Type: Schwann Cells, Source: Mouse PubMed
65 Liu, G., Ng, H., Akasaki, Y., Yuan, X., Ehtesham, M., Yin, D., Black , K.L. and Yu, J.S. (2004) Small interference RNA modulation of IL-10 in human monocyte-derived dendritic cells enhances the Th1 response. Eur. J. Immunol. 34: 1680-1687.

Cell Line: Primary, Cell Type: Dendritic Cells, Source: Mouse PubMed
66 Ahn, S., Wei, H., Garrison, T.R. and Lefkowitz, R.J. (2004) Reciprocal Regulation of Angiotensin Receptor-activated Extracellular Signal-regulated Kinases by (beta)-Arrestins 1 and 2. J. Biol. Chem. 279: 7807-7811.

Cell Line: HEK 293, Cell Type: Embryonic Kidney, Source: Human PubMed
67 Ren, J., Shi, M., Liu, R., Yang, Q-H., Johnson, T., Skarnes, W.C. and Du, C. (2005) The Birc6 (Bruce) gene regulates p53 and the mitochondrial pathway of apoptosis and is essential for mouse embryonic development. Proc. Natl. Acad. Sci. USA. 102(3): p. 56

Cell Line: H460, Cell Type: Lung Cancer, Source: Human PubMed
68 Saotome, M., Safiulina, D., Szabadkai, G., Das, S., Fransson, A., Aspenstrom, P., Rizzuto, R. and Hajnoczky, G. (2008) Bidirectional Ca2+-dependent control of mitochondrial dynamics by the Miro GTPase. Proc Natl Acad Sci U S A 105(52): p. 20728.

Cell Line: H9c2, Cell Type: Myoblast, Source: Rat PubMed
69 Huang, W., Eum, S.Y., Andras, I.E., Hennig, B. and Toborek, M. (2009) PPAR{alpha} and PPAR{gamma} attenuate HIV-induced dysregulation of tight junction proteins by modulations of matrix metalloproteinase and proteasome activities. FASEB J 13 Jan 2009.

Cell Line: hCMEC/D3, Cell Type: Brain Microvascular Endothelia, Source: Human PubMed
70 Yao, K., Shida, S., Selvakumaran, M., Zimmerman, R., Simon, E., Schick, J., Haas, N.B., Balke, M., Ross, H., Johnson, S.W. and O"Dwyer, P.J. (2005) Macrophage Migration Inhibitory Factor Is a Determinant of Hypoxia-Induced Apoptosis in Colon Cancer Cell L

Cell Line: HCP40, Cell Type: Colon adenocarcinoma, Source: null PubMed
71 Wang, J., Rajput, A., Kan, J.L.C., Rose, R., Liu, X., Kuropatwinski, K., Hauser, J., Beko, A., Dominquez, I., Sharratt, E.A., Brattain, L., LeVea, C., Sun, F., Keane, D.M., Gibson, N.W. and Michael G. Brattain (2009) Knockdown of Ron kinase inhibits mutan

Cell Line: HCT-116, Cell Type: Colon Carcinoma, Source: Human PubMed
72 Yao, K., Shida, S., Selvakumaran, M., Zimmerman, R., Simon, E., Schick, J., Haas, N.B. Balke, M., Ross, H., Johnson, S.W. and O"Dwyer, P.J. (2005) Macrophage Migration Inhibitory Factor Is a Determinant of Hypoxia-Induced Apoptosis in Colon Cancer Cell Li

Cell Line: HCT-116, Cell Type: Colon Adenocarcinoma, Source: Human PubMed
73 Shikama, Y., Yamada, M., Miyashita, T. (2004) Caspase-8 and caspase-10 activate NF-B through RIP, NIK and IKK kinases. Eur. J. Immun. 33 (7): 1998-2006.

Cell Line: HEK 293, Cell Type: Embryonic Kidney, Source: Human PubMed
74 Ahn, S., Shenoy, S.K., Wei, H. and Lefkowitz, R.J. (2004) Differential Kinetic and Spatial Patterns of {beta}-Arrestin and G Protein-mediated ERK Activation by the Angiotensin II Receptor. J. Biol. Chem. 279 (34): 35518-35525.

Cell Line: HEK 293, Cell Type: Embryonic Kidney, Source: Human PubMed
75 Jing, H., Yen, J-H and Ganea, D. (2004) A novel signaling pathway mediates the inhibition of CCL3/4 expression by PGE2. J. Biol. Chem. 279(53): p. 55176-55186.

Cell Line: DC2.4, Cell Type: Bone Marrow, Source: Mouse PubMed
76 Kim, J., Ahn, S., Ren, X-R., Whalen, E.J., Reiter, E., Wei, H. and Lefkowitz, R.J. (2005) Functional antagonism of different G protein-coupled receptor kinases for {beta}-arrestin-mediated angiotensin II receptor signaling. Proc. Natl. Acad. Sci.?102: 144

Cell Line: HEK 293, Cell Type: Embryonic Kidney, Source: Human PubMed
77 Kohout, T.A., Nicholas, S.L., Perry, S.J., Reinhart, G., Junger, S. and Struthers, R. (2004) Differential Desensitization, Receptor Phosphorylation, {beta}-Arrestin Recruitment, and ERK1/2 Activation by the Two Endogenous Ligands for the CC Chemokine Rece

Cell Line: HEK 293, Cell Type: Embryonic Kidney, Source: Human PubMed
78 Liang, Y., Yu, W., Li, Y., Yan, X., Huang, Q. and Zhu, X. (2004) Nudel functions in membrane traffic mainly through association with Lis1 and cytoplasmic dynein. J. Cell Biol. 164 (4): 557-566.

Cell Line: HEK 293, Cell Type: Embryonic Kidney, Source: Human PubMed
79 Ren, X-R., Reiter, E., Ahn, S., Kim, J., Chen, W. and Lefkowitz, R.J. (2005) Different G protein-coupled receptor kinases govern G protein and {beta}-arrestin-mediated signaling of V2 vasopressin receptor. Proc. Natl. Acad. Sci. 102: 1448 - 1453.

Cell Line: HEK 293, Cell Type: Embryonic Kidney, Source: Human PubMed
80 Zhang, Y-A., Nemunaitis, J., Samuel, S.K., Chen, P., Shen, Y. and Tong, A.W. (2006) Antitumor Activity of an Oncolytic Adenovirus-Delivered Oncogene Small Interfering RNA. Cancer Res. 66(19): 9736-9743.

Cell Line: H441, Cell Type: Lung Adenocarcinoma, Source: Human PubMed
81 Ahn, S., Nelson, C.D., Garrison, T.R., Miller, W.E. and Lefkowitz, R.J. (2003) Desensitization, internalization, and signaling functions of -arrestins demonstrated by RNA interference. Proc. Natl. Acad. Sci. 100: 1740 - 1744.

Cell Line: HEK 293, Cell Type: Embryonic Kidney, Source: Human PubMed
82 Mizuarai, S., Miki, S., Araki, H., Takahashi, K. and Kotani, H.(2005) Identification of Dicarboxylate Carrier Slc25a10 as Malate Transporter in de Novo Fatty Acid Synthesis. J. Biol. Chem.280(37): p. 32434-32441.

Cell Line: 3T3-L1, Cell Type: Embryo, Source: Swiss Mouse PubMed
83 Ito, K., Yamamura, S., Essilfie-Quaye, S., Cosio, B., Ito, M., Barnes, P.J. and Adcock, I.M. (2006) Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF??B suppression. J. Exp. Med. 203(1): 7-13.

Cell Line: A549, Cell Type: Lung Carcinoma, Source: Human PubMed
84 Stepulak, A., Sifringer, M., Rzeski, W., Endesfelder, S., Gratopp, A., Pohl, E.E., Bittigau, P., Hansen, H.H., Stryjecka-Zimmer, M., Turski, L. and Ikonomidou, C. (2005) NMDA antagonist inhibits the extracellular signal-regulated kinase pathway and suppre

Cell Line: A549, Cell Type: Lung Carcinoma, Source: Human PubMed
85 Varro, A., Noble, P-J. M., Pritchard, D.M., Kennedy, S., Hart, C.A., Dimaline, R. and Dockray, G.J. (2004) Helicobacter pylori Induces Plasminogen Activator Inhibitor 2 in Gastric Epithelial Cells through Nuclear Factor-B and RhoA: Implications for Invasi

Cell Line: AGS, Cell Type: Gastric Epithelium, Source: Human PubMed
86 Huang, B., Zhao, J., Shen, S., Li, H., He, K-L, Shen, G-X, Mayer, L., Unkeless, J., Li, D., Yuan, Y., Zhang, G.-M., Xiong, H. and Feng, Z.-H. (2007) Listeria monocytogenes Promotes Tumor Growth via Tumor Cell Toll-Like Receptor 2 Signaling. Cancer Res. 67

Cell Line: H22, Cell Type: Hepatoma, Source: Mouse PubMed
87 Liang, X-J, Finkel, T., Shen, D-W, Yin, J-J, Aszalos, A. and Gottesman, M.M. (2008) SIRT1 Contributes in Part to Cisplatin Resistance in Cancer Cells by Altering Mitochondrial Metabolism. Mol Cancer Res 6(9): 1499-506.

Cell Line: GS-KB-3-1, Cell Type: Epidermoid Adenocarcinoma, Source: Human PubMed
88 Nunes, R.O., Schmidt, M., Dueck, G., Baarsma, H., Halayko, A.J., Kerstjens, H.A.M., Meurs, H. and Gosens, R. (2008) GSK-3/??-catenin signaling axis in airway smooth muscle: role in mitogenic signaling Am J Physiol Lung Cell Mol Physiol. 294: L1110 - L1118

Cell Line: Bronchial, Cell Type: Smooth Muscle, Source: Human PubMed
89 Zhou, X., Stuart, A., Dettin, L.E., Rodriguez, G., Hoel, B. and Gallicano G.I. (2004) Desmoplakin is required for microvascular tube formation in culture. J. Cell Sci. 117: 3129-3140.

Cell Line: C166, Cell Type: Yolk Sack Endothelium, Source: Mouse PubMed
90 Evangelisti, C., Tazzari, P.L., Riccio, M., Fiume, R., Hozumi, Y., Fala, F., Goto, K.., Manzoli, L., Cocco, L. and Martelli, A.M. (2007) Nuclear diacylglycerol kinase-?? is a negative regulator of cell cycle progression in C2C12 mouse myoblasts. FASEB J.

Cell Line: C2C12, Cell Type: Myoblast, Source: Mouse PubMed
91 Saarikangas, J., Hakanen, J., Mattila, P.K., Grumet, M., Salminen, M. and Lappalainen, P. (2008) ABBA regulates plasma-membrane and actin dynamics to promote radial glia extension. J Cell Sci. 121(Pt 9):1444-54.

Cell Line: C6R, Cell Type: Glioma, Source: Rat PubMed
92 Kheifets, V., Bright, R., Inagaki, K., Schechtman, D. and Mochly-Rosen, D. (2006) Protein Kinase C ?? PKC-Annexin V Interaction: a required step in ?? PKC translocation and function. J. Biol. Chem. 281(32): p. 23218-23226.

Cell Line: CHO-K1, Cell Type: Ovary, Source: Chinese Hamster PubMed
93 Wei, H., Ahn, S., Barnes, W.G. and Lefkowitz, R.J., (2004) Stable interaction between beta -arrestin2 and AT 1A receptor is required for beta -arrestin2 mediated activation of extracellular signal-regulated kinase 1 and 2. J. Biol. Chem. 279: 48255-48261.

Cell Line: HEK 293, Cell Type: Embryonic Kidney, Source: Human PubMed
94 Tran, T., Ens-Blackie, K., Rector, E.S., Stelmack, G.L., McNeill, K.D., Tarone, G., Gerthoffer, W.T., Unruh, H. and Halayko, A.J. (2007) Laminin-binding Integrin ??7 is Required for Contractile Phenotype Expression by Human Airway Myocyte. Am. J. Respir.

Cell Line: ASM Transformed, Cell Type: Airway Smooth Muscle Cells, Source: Human PubMed
95 Pastorino, J.G. and Shulga, N. (2008) TNFalpha can provoke cleavage and activation of sterol regulatory element binding protein in ethanol exposed cells via a caspase dependent pathway that is cholesterol-insensitive. J. Biol. Chem. 283: 25638 - 25649.

Cell Line: HepG2, Cell Type: Hepatocellular Carcinoma, Source: Human PubMed
96 Chung, J-S., Sato, K., Dougherty, I.I., Cruz, Jr., P.D. and Ariizumi, K. (2007) DC-HIL is a negative regulator of T lymphocyte activation. Blood. 109(10): p. 4320-4327.

Cell Line: HeLa, Cell Type: Cervical Carcinoma, Source: Human PubMed
97 Kheifets, V., Bright, R., Inagaki, K., Schechtman, D. and Mochly-Rosen, D. (2006) Protein Kinase C ??}PKC)-Annexin V Interaction: a required step in ?? PKC translocation and function. J. Biol. Chem. 281(32): p. 23218-23226.

Cell Line: HeLa, Cell Type: Cervical Carcinoma, Source: Human PubMed
98 Layzer, J.M., McCaffrey, A.P., Tanner, A.K., Huang, Zan, Kay, Mark A. and Sullenger, B.A. (2004) In vivo activity of nuclease-resistant siRNAs. RNA 10 (5): p. 766-771.

Cell Line: HeLa, Cell Type: Cervical Carcinoma, Source: Human PubMed
99 Pomerening, J.R., Ubersax, J.A. and Ferrell, J.E., Jr. (2008) Rapid Cycling and Precocious Termination of G1 Phase in Cells Expressing CDK1AF. Mol. Biol. Cell, 19: 3426 - 3441.

Cell Line: HeLa, Cell Type: Cervical Carcinoma, Source: Human PubMed
100 Shulga, N. and Pastorino, J.G. (2006) Acyl Coenzyme A-binding Protein Augments Bid-induced Mitochondrial Damage and Cell Death by Activating ??-Calpain. J. Biol. Chem. 281(41): 30824-30833.

Cell Line: HeLa, Cell Type: Cervical Carcinoma, Source: Human PubMed
101 Witherow, D.S., Garrison, T.R., Miller, W.E. and Robert J. Lefkowitz (2004) {beta}-Arrestin inhibits NF-{kappa}B activity by means of its interaction with the NF-{kappa}B inhibitor I{kappa}B{alpha}. Proc. Natl. Acad. Sci. USA 101: 8603-8607.

Cell Line: HeLa, Cell Type: Cervical Carcinoma, Source: Human PubMed
102 Shenoy, S.K., Drake, M.T., Nelson, C.D., Houtz, D.A., Xiao, K., Madabushi, S., Reiter, E., Premont, R.T., Lichtarge, O. and Lefkowitz, R.J. (2006) {beta}-Arrestin-dependent, G Protein-independent ERK1/2 Activation by the {beta}2 Adrenergic Receptor. J. Bi

Cell Line: HEK 293, Cell Type: Embryonic Kidney, Source: Human PubMed
103 Zhu, S., Wang, W., Clarke, D.C. and Liu, X. (2007) Activation of Mps1 Promotes Transforming Growth Factor-??-independent Smad Signaling. J. Biol Chem. 282 (25) 18327-18338.

Cell Line: HeLa, Cell Type: Cervical Carcinoma, Source: Human PubMed
104 Violin, J.D., DeWire, S.M., Barnes, W.G. and Lefkowitz, R.J. (2006) G Protein-Coupled Receptor Kinase and ??-arrestin mediated desensitization of the angiotensin II type 1A receptor elucidated by diacylgylcerol dynamics. J. Biol. Chem. 281: 36411 - 36419.

Cell Line: HEK-293, Cell Type: Embryonic Kidney, Source: Human PubMed
105 Smirnova, I.V., Kajstura, M., Sawamura, T. and Goligorsky, M.S. (2004) Asymmetric dimethylarginine upregulates LOX-1 in activated macrophages: role in foam cell formation. AJP: Heart 287(2): p. H782-H790

Cell Line: HL-60, Cell Type: Peripheral Blood Promyelocytic Leukemia, Source: Human PubMed
106 Berdyshev, E.V., Gorshkova, I., Skobeleva, A., Bittman, R., Lu, X., Dudek, S.M., Mirzapoiazova, T., Garcia, J.G.N. and Natarajan, V. (2009) FTY720 inhibits ceramide synthases and upregulates dihydrosphingosine-1-phosphate formation in human lung endotheli

Cell Line: HPAEC, Cell Type: Pulmonary Artery Endothelium, Source: Human PubMed
107 Maneechotesuwan, K., Xin, Y., Ito, K., Jazrawi, E., Lee, K-Y., Usmani, O.S., Barnes, P.J. and Adcock, I.M. (2007) Regulation of Th2 Cytokine Genes by p38 MAPK-Mediated Phosphorylation of GATA-3. J. Immunol. 178(4): 2491-2498.

Cell Line: HUT-78, Cell Type: T Cells, Source: Human PubMed
108 Abboud-Jarrous, G., Atzmon, R., Peretz, T., Palermo, C., Gadea, B.B., Joyce, J.A. and Vlodavsky, I. (2008) Cathepsin L Is Responsible for Processing and Activation of Proheparanase through Multiple Cleavages of a Linker Segment. J. Biol. Chem. 283: 18167

Cell Line: JAR, Cell Type: Choriocarcinoma, Source: Human PubMed
109 Yang, Q-H, Church-Hajduk, R., Ren, J., Newton, M.L. and Du, C. (2003) Omi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosis. Genes & Dev. 17: 1487 - 1496.

Cell Line: HeLa, Cell Type: Cervical Carcinoma, Source: Human PubMed
110 IM Kim, DG Tilley, J Chen, NC Salazar, EJ Whalen, JD Violin, and HA Rockman (2008) Beta-blockers alprenolol and carvedilol stimulate beta-arrestin-mediated EGFR transactivation. Proc Natl Acad Sci 105(38): 14555-60.

Cell Line: HEK-293, Cell Type: Embryonic Kidney, Source: Human PubMed
111 Wei, H., Ahn, S., Shenoy, S.K., Karnik, S.S., Hunyady, L., Luttrell, L.M. and Lefkowitz, R.J. (2003) Independent -arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2. Proc. Natl. Acad.

Cell Line: HEK 293, Cell Type: Embryonic Kidney, Source: Human PubMed
112 Wu, J-H, Goswami, R., Kim, L.K., Miller, W.E., Peppel, K. and Freedman, N.J. (2005) The Platelet-derived Growth Factor Receptor-{beta} Phosphorylates and Activates G Protein-coupled Receptor Kinase-2: a Mechanism for Feedback Inhibition. J. Biol. Chem. 28

Cell Line: HEK 293, Cell Type: Embryonic Kidney, Source: Human PubMed
113 Ahn, S., Kim, J., Hara, M.R., Ren, X. and Lefkowitz, R.J. (2009) ?? -arrestin2 mediates anti-apoptotic signaling through regulation of bad phosphorylation. J Biol Chem 284(13): 8855-65.

Cell Line: HEK-293, Cell Type: Embryonic Kidney, Source: Human PubMed
114 Barthet, G., Framery, B., Gaven, F., Pellissier, L., Reiter, E., Claeysen, S., Bockaert, J. and Dumuis, A. (2007) 5-Hydroxytryptamine 4 Receptor Activation of the Extracellular Signal-regulated Kinase Pathway Depends on Src Activation but Not on G Protein

Cell Line: HEK-293, Cell Type: Embryonic Fibroblast, Source: Human PubMed
115 El-Shewy, H.M., Johnson, K.R., Lee, M-H, Jaffa, A.A., Obeid, L.M. and Luttrell, L.M. (2006) Insulin-like Growth Factors Mediate Heterotrimeric G Protein-dependent ERK1/2 Activation by Transactivating Sphingosine 1-Phosphate Receptors . J. Biol. Chem. 281(

Cell Line: HEk-293, Cell Type: Embryonic Kidney, Source: Human PubMed
116 Cassimeris, L. and Morabito, J. (2004) TOGp, the Human Homolog of XMAP215/Dis1, Is Required for Centrosome Integrity, Spindle Pole Organization, and Bipolar Spindle Assembly. Mol. Biol. Cell 15 (4): 1580-1590.

Cell Line: HeLa, Cell Type: Cervical Carcinoma, Source: Human PubMed
117 Gesty-Palmer, D., Chen, M., Reiter, E., Ahn, S., Nelson, C.D., Wang, S., Eckhardt, A.E., Cowan, C.L., Spurney, R.F., Luttrell, L.M. and Lefkowitz, R.J. (2006) Distinct beta-Arrestin- and G Protein-dependent Pathways for Parathyroid Hormone Receptor-stimul

Cell Line: HEK-293, Cell Type: Embryonic Kidney, Source: Human PubMed
118 Bentley, A.M., Normand, G., Hoyt, J. and King, R.W. (2007) Distinct Sequence Elements of Cyclin B1 Promote Localization to Chromatin, Centrosomes, and Kinetochores during Mitosis. Mol. Biol. Cell, Dec 2007; 18: 4847 - 4858.

Cell Line: HeLa, Cell Type: Cervical Carcinoma, Source: Human PubMed
119 Kani, S., Nakayama, E., Yoda, A., Onishi, N., Sougawa, N., Hazaka, Y., Umeda, T., Takeda, K., Ichijo, H., Hamada, Y. and Minami, Y. (2007) Chk2 kinase is required for methylglyoxal-induced G2/M cell-cycle checkpoint arrest: implication of cell-cycle check

Cell Line: HEK-293, Cell Type: Embryonic Kidney, Source: Human PubMed
120 Kara, E., Crepieux, P., Gauthier, C., Martinat, N., Piketty, V., Guillou, F., and Reiter, E. (2006) A Phosphorylation Cluster of Five Serine and Threonine Residues in the C-Terminus of the Follicle-Stimulating Hormone Receptor Is Important for Desensitiza

Cell Line: HEk-293, Cell Type: Embryonic Kidney, Source: Human PubMed
121 Nelson, C.D., Kovacs, J.J., Nobles, K.N., Whalen, E.J. and Lefkowitz, R.J. (2008) ??-Arrestin Scaffolding of Phosphatidylinositol 4-Phosphate 5-Kinase I?? Promotes Agonist-stimulated Sequestration of the {beta}2-Adrenergic Receptor. J. Biol. Chem. 283(30)

Cell Line: HEK-293, Cell Type: Embryonic Kidney, Source: Human PubMed
122 Noma, T., Lemaire, A., Prasad, S.V.N., Barki-Harrington, L., Tilley, D.G., Chen, J., Le Corvoisier, P., Violin, J.D., Wei, H., Lefkowitz, R.J. and Rockman, H.A. (2007) ??-Arrestin mediated ??1-adrenergic receptor transactivation of the EGFR confers cardio

Cell Line: HEK-293, Cell Type: Embryonic Kidney, Source: Human PubMed
123 Rajagopal, K., Whalen, E.J., Violin, J.D., Stiber, J.A., Rosenberg, P.B., Premont, R.T., Coffman, T.M., Rockman, H.A. and Lefkowitz, R.J. (2006) ??-Arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes. P

Cell Line: HEk-293, Cell Type: Embryonic Kidney, Source: Human PubMed
124 Shenoy, S.K., Xiao, K., Venkataramanan, V., Snyder, P.M., Freedman, N.J. and Weissman, A.M. (2008) NEDD4 mediates agonist-dependent ubiquitination, lysosomal targeting and degradation of the beta 2 adrenergic receptor. J. Biol. Chem. 283: 22166 - 22176.

Cell Line: HEK-293, Cell Type: Embryonic Kidney, Source: Human PubMed
125 Nguyen, J.T. and Wells, J.A. (2003) Direct activation of the apoptosis machinery as a mechanism to target cancer cells. Proc. Natl. Acad. Sci. 100: 7533  7538.

Cell Line: Jurkat, Cell Type: T-Cell Lymphoma, Source: Human PubMed
126 El-Shewy, H.M., Lee, M-H., Obeid, L.M., Jaffa, A.A. and Luttrell, L.M. (2007) The Insulin-like Growth Factor Type 1 and Insulin-like Growth Factor Type 2/Mannose-6-phosphate Receptors Independently Regulate ERK1/2 Activity in HEK293 Cells. J. Biol. Chem.

Cell Line: HEK-293, Cell Type: Embryonic Kidney, Source: Human PubMed
127 Qu H et al. miRNA-558 promotes tumorigenesis and aggressiveness of neuroblastoma cells through activating the transcription of heparanase. Hum. Mol. Genet. 2015 May;24(9):2539-51
Qu H et al
2015/01/01
PubMed
128 Jean-Charles PY et al. Ubiquitin-specific Protease 20 Regulates the Reciprocal Functions of β-Arrestin2 in Toll-like Receptor 4-promoted Nuclear Factor κB (NFκB) Activation. J. Biol. Chem. 2016 Apr;291(14):7450-64
Jean-Charles PY et al
2016/01/01
PubMed
129 Lorin C et al. Dystrophic cardiomyopathy: role of TRPV2 channels in stretch-induced cell damage. Cardiovasc. Res. 2015 Apr;106(1):153-62
Lorin C et al
2015/01/01
PubMed
  • No.: 1
  • 文献情報:
    de Barry, J., Janoshazi, A., Luc Dupont, J., Procksch, O., Chasserot-Golaz, S., Jeromin, A. and Vitale, N. (2006) Functional Implication of Neuronal Calcium Sensor-1 and Phosphoinositol 4-Kinase-?? Interaction in Regulated Exocytosis of PC12 Cells. J. Bio

  • 備考:
    Cell Line: PC-12, Cell Type: Pheochromocytoma, Source: Rat
  • 参照:
    PubMed
  • No.: 2
  • 文献情報:
    Amaral, M.D. and Pozzo-Miller, L. (2007) TRPC3 Channels Are Necessary for Brain-Derived Neurotrophic Factor to Activate a Nonselective Cationic Current and to Induce Dendritic Spine Formation. J. Neurosci. 27(19): p. 5179-5189.

  • 備考:
    Cell Line: Primary, Cell Type: Hippocampal Neurons, Source: Rat
  • 参照:
    PubMed
  • No.: 3
  • 文献情報:
    Khundmiri, S.J., Dean, W.L., McLeish, K.R. and Lederer, E.D. (2005) Parathyroid Hormone-mediated Regulation of Na+-K+-ATPase Requires ERK-dependent Translocation of Protein Kinase C{alpha}. J. Biol. Chem. 280(10): p. 8705-8713.

  • 備考:
    Cell Line: OK, Cell Type: Kidney, Source: Opossum
  • 参照:
    PubMed
  • No.: 4
  • 文献情報:
    Aleyasin, H., Cregan, S.P., Iyirhiaro, G., OHare, M.J., Callaghan, S.M., Slack, R.S. and Park, D.S. (2004) Nuclear Factor-B Modulates the p53 Response in Neurons Exposed to DNA Damage. J. Neurosci. 24 (12): 2963-2973.

  • 備考:
    Cell Line: Primary, Cell Type: Cortical Neurons, Source: Mouse
  • 参照:
    PubMed
  • No.: 5
  • 文献情報:
    Khundmiri, S.J., Ameen, M., Delamere, N.A. and Lederer, E.D. (2008) PTH-mediated regulation of Na+ -K+ -ATPase requires Src kinase-dependent ERK Phosphorylation. Am J Physiol Renal Physiol. 295(2): F426-F437.

  • 備考:
    Cell Line: OK, Cell Type: Kidney, Source: Opossum
  • 参照:
    PubMed
  • No.: 6
  • 文献情報:
    Aarts, M., Lihara, K., Wei, W-L, Xiong, Z-G, Arundine, M., Cerwinski, W., MacDonald, J.F., Tymianski, M. (2003) A Key Role for TRPM7 Channels in Anoxic Neuronal Death. Cell 115: 863.

  • 備考:
    Cell Line: Primary, Cell Type: Cortical Neurons, Source: Mouse
  • 参照:
    PubMed
  • No.: 7
  • 文献情報:
    Asmis, R., Wang, Y., Xu, L., Kisgati, M., Begley, J.G. and?Mieyal, J.J. (2005) A novel thiol oxidation-based mechanism for adriamycin-induced cell injury in human macrophages. FASEB J. published 13 September 2005, 10.1096/fj.04-2991fje.

  • 備考:
    Cell Line: Primary, Cell Type: Macrophage, Source: Human
  • 参照:
    PubMed
  • No.: 8
  • 文献情報:
    Birukova, A.A., Chatchavalvanich, S., Rios, A., Kawkitinarong, K., Garcia, J.G.N. and Birukov, K.G. (2006) Differential Regulation of Pulmonary Endothelial Monolayer Integrity by Varying Degrees of Cyclic Stretch. Am. J. Pathol. 168: 1749 - 1761.

  • 備考:
    Cell Line: Primary, Cell Type: Pulmonary Artery Endothelium, Source: Human
  • 参照:
    PubMed
  • No.: 9
  • 文献情報:
    Chung, J-S, Sato, K., Dougherty, I.I., Cruz, Jr., P.D. and Ariizumi, K. (2007) DC-HIL is a negative regulator of T lymphocyte activation. Blood. 109(10): p. 4320-4327.

  • 備考:
    Cell Line: Primary, Cell Type: Dendritic Cells (Bone Marrow), Source: Mouse
  • 参照:
    PubMed
  • No.: 10
  • 文献情報:
    Cui, H., Hayashi, A., Sun, H-S, Belmares, M.P., Cobey, C., Phan, T., Schweizer, J., Salter, M.W., Wang, Y.T., Tasker, R.A., Garman, D., Rabinowitz, J., Lu, P.S. and Tymianski, M. (2007) PDZ Protein Interactions Underlying NMDA Receptor-Mediated Excitotoxi

  • 備考:
    Cell Line: Primary, Cell Type: Cortical Neurons, Source: Mouse
  • 参照:
    PubMed
  • No.: 11
  • 文献情報:
    Hayashi, H., Campenot, R.B., Vance, D.E. and Vance, J.E. (2007) Apolipoprotein E-Containing Lipoproteins Protect Neurons from Apoptosis via a Signaling Pathway Involving Low-Density Lipoprotein Receptor-Related Protein-1. J. Neurosci. 27(8): 1933-1941.

  • 備考:
    Cell Line: Primary, Cell Type: Retinal Ganglion, Source: Rat
  • 参照:
    PubMed
  • No.: 12
  • 文献情報:
    Haruhisa Higuchi, Toshihide Yamashita, Hideki Yoshikawa, and Masaya Tohyama (2003) Functional inhibition of the p75 receptor using a small interfering RNA. Biochem. & Biophys. Res. Comm. 301: 804809.

  • 備考:
    Cell Line: Primary, Cell Type: Dorsal Root Ganglion Neurons, Source: Mouse
  • 参照:
    PubMed
  • No.: 13
  • 文献情報:
    Ge, L., Shenoy, S.K., Lefkowitz, R.J. and DeFea, K.A. (2004) Constitutive protease-activated-receptor-2 mediated migration of MDA MB-231 breast cancer cells requires both beta-arrestin-1 and 2. J. Biol. Chem. 279(53): p. 55419-55424.

  • 備考:
    Cell Line: MDA MB-231, Cell Type: Breast Cancer, Source: Human
  • 参照:
    PubMed
  • No.: 14
  • 文献情報:
    Dandapat, A., Hu, C., Sun, L. and Mehta, J.L. (2007) Small Concentrations of oxLDL Induce Capillary Tube Formation From Endothelial Cells via LOX-1 Dependent Redox-Sensitive Pathway. Arterioscler Thromb Vasc Biol.

  • 備考:
    Cell Line: Primary, Cell Type: Coronary Artery Endothelial, Source: Human HCAEC
  • 参照:
    PubMed
  • No.: 15
  • 文献情報:
    de Beer, M.C., Zhao, Z., Webb, N.R., van der Westhuyzen, D.R. and de Villiers, W.J.S. (2003) Lack of a direct role for macrosialin in oxidized LDL metabolism J. Lipid Res. 44: 674 - 685.

  • 備考:
    Cell Line: Primary, Cell Type: Peritoneal Macrophage, Source: Mouse
  • 参照:
    PubMed
  • No.: 16
  • 文献情報:
    Burkhalter, J., Fiumelli, H., Erickson, J.D. and Martin, J-L. (2007) A critical role for system a amino acid transport in the regulation of dendritic development by BDNF. J Biol Chem 282: 5152 - 5159.

  • 備考:
    Cell Line: Primary, Cell Type: Cortical Neurons, Source: Mouse
  • 参照:
    PubMed
  • No.: 17
  • 文献情報:
    Zoudilova, M., Kumar, P., Ge, L., Wang, P., Bokoch, G. M. and DeFea, K. A. (2007) ??-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2. J. Biol. Chem. 282: 20634 - 20646.

  • 備考:
    Cell Line: MDA-MB-468, Cell Type: Breast Carcinoma, Source: Human
  • 参照:
    PubMed
  • No.: 18
  • 文献情報:
    Park, S-Y., Kang, K-B., Thapa, N., Kim, S-Y., Lee, S-J. and Kim, I-S. (2008) Requirement of Adaptor Protein GULP during Stabilin-2-mediated Cell Corpse Engulfment. J. Biol. Chem. 283(16): 10593-10600.

  • 備考:
    Cell Line: L/Stab-2, Cell Type: Fibroblast, Source: Mouse
  • 参照:
    PubMed
  • No.: 19
  • 文献情報:
    Takayama, K., Tsutsumi, S., Suzuki, T., Horie-Inoue, K., Ikeda, K., Kaneshiro, K. Fujimura, T., Kumagai, J., Urano, T., Sakaki, Y., Shirahige, K., Sasano, H., Takahashi, S., Kitamura, T., Ouchi, Y., Aburatani, H. and Inoue, S. (2009) Amyloid precursor pro

  • 備考:
    Cell Line: LNCaP, Cell Type: Prostate Cancer, Source: Human
  • 参照:
    PubMed
  • No.: 20
  • 文献情報:
    Liu, X., Yao, M., Li, N., Wang, C., Zheng, Y. and Cao, X. (2008) CaMKII promotes TLR-triggered proinflammatory cytokine and type I interferon production by directly binding and activating TAK1 and IRF3 in macrophages. Blood. 112(13): 4961-4970.

  • 備考:
    Cell Line: RAW 264.7, Cell Type: Macrophage, Source: Mouse
  • 参照:
    PubMed
  • No.: 21
  • 文献情報:
    Hengst, U. Cox, L.J., Macosko, E.Z. and Jaffrey, S.R. (2006) Functional and Selective RNA Interference in Developing Axons and Growth Cones. J. Neurosci. 26(21): 5727-5732.

  • 備考:
    Cell Line: Primary, Cell Type: Dorsal Root Ganglion, Source: Rat
  • 参照:
    PubMed
  • No.: 22
  • 文献情報:
    Scott, M.G.H., Pierotti, V., Storez, H., Lindberg, E., Thuret, A., Muntaner, O., Labbe-Jullie, C., Pitcher, J.A. and Marullo, S. (2006) Cooperative Regulation of Extracellular Signal-Regulated Kinase Activation and Cell Shape Change by Filamin A and ??-Ar

  • 備考:
    Cell Line: M2, Cell Type: Melanoma, Source: Human
  • 参照:
    PubMed
  • No.: 23
  • 文献情報:
    Pastorino, J.G. and Shulga, N. (2008) Tumor Necrosis Factor-{alpha} Can Provoke Cleavage and Activation of Sterol Regulatory Element-binding Protein in Ethanol-exposed Cells via a Caspase-dependent Pathway That Is Cholesterol Insensitive. J. Biol. Chem. 2

  • 備考:
    Cell Line: McA-RH 7777, Cell Type: Hepatoma, Source: Rat
  • 参照:
    PubMed
  • No.: 24
  • 文献情報:
    Abboud-Jarrous, G., Atzmon, R., Peretz, T., Palermo, C., Gadea, B.B., Joyce, J.A.and Vlodavsky, I. (2008) Cathepsin L Is Responsible for Processing and Activation of Proheparanase through Multiple Cleavages of a Linker Segment. J. Biol. Chem. 283: 18167 -

  • 備考:
    Cell Line: MDA-MB-435, Cell Type: Melanoma, Source: Human
  • 参照:
    PubMed
  • No.: 25
  • 文献情報:
    Nomachi, A., Nishita, M., Inaba, D., Enomoto, M., Hamasaki, M. and Minami, Y. (2008) Receptor Tyrosine Kinase Ror2 Mediates Wnt5a-induced Polarized Cell Migration by Activating c-Jun N-terminal Kinase via Actin-binding Protein Filamin A. J. Biol. Chem. 28

  • 備考:
    Cell Line: NIH-3T3, Cell Type: Fibroblast, Source: Mouse
  • 参照:
    PubMed
  • No.: 26
  • 文献情報:
    Ichikawa, T., Horie-Inoue, K., Ikeda, K., Blumberg, B. and Inoue, S. (2007) Vitamin K2 induces phosphorylation of protein kinase A and expression of novel target genes in osteoblastic cells. J Mol Endocrinol 1 39 (4): 239.

  • 備考:
    Cell Line: MG63, Cell Type: Osteosarcoma, Source: Human
  • 参照:
    PubMed
  • No.: 27
  • 文献情報:
    Nagasako, T., Sugiyama, T., Mizushima, T., Miura, Y., Kato, M. and Asaka, M. (2003) Up-regulated Smad5 Mediates Apoptosis of Gastric Epithelial Cells Induced by Helicobacter pylori Infection. J. Biol. Chem.: 278: 4821 - 4825.

  • 備考:
    Cell Line: MKN 28, Cell Type: Gastric Epithelium, Source: Human
  • 参照:
    PubMed
  • No.: 28
  • 文献情報:
    Yang, X., Liu, L., Sternberg, D., Tang, L., Galinsky, I., DeAngelo, D. and Stone, R. (2005) The FLT3 Internal Tandem Duplication Mutation Prevents Apoptosis in Interleukin-3-Deprived BaF3 Cells Due to Protein Kinase A and Ribosomal S6 Kinase 1-Mediated BA

  • 備考:
    Cell Line: MV-4-11, Cell Type: Biophenotypic B Myelomonocytic Leukemia, Source: Human
  • 参照:
    PubMed
  • No.: 29
  • 文献情報:
    Bertling, E., Hotulainen, P., Mattila, P.K., Matilainen, T., Salminen, M., and Lappalainen, P. (2004) Cyclase-associated-protein 1 (CAP1) promotes cofilin-induced actin dynamics in mammalian nonmuscle cells. Mol. Biol. Cell 15 (5): p. 2324-2334.

  • 備考:
    Cell Line: Neuro2a, Cell Type: Neuroblastoma, Source: Mouse
  • 参照:
    PubMed
  • No.: 30
  • 文献情報:
    Hotulainen, P., Paunola, E., Vartiainen, M.K. and Lappalainen, P. (2005) Actin-depolymerizing Factor and Cofilin-1 Play Overlapping Roles in Promoting Rapid F-Actin Depolymerization in Mammalian Nonmuscle Cells. Mol. Biol. Cell. 16(2): p. 649-664.

  • 備考:
    Cell Line: NIH-3T3, Cell Type: Fibroblast, Source: Mouse
  • 参照:
    PubMed
  • No.: 31
  • 文献情報:
    Ikeda, K., Ogawa, S., Tsukui, T., Horie-Inoue, K., Ouchi, Y., Kato, S., Muramatsu, M. and Inoue, S. (2004) Protein Phosphatase 5 Is a Negative Regulator of Estrogen Receptor-mediated Transcription. Mol. Endocrinol. 18(5): 1131-1143.

  • 備考:
    Cell Line: MCF-7, Cell Type: Breast Adenocarcinoma, Source: Human
  • 参照:
    PubMed
  • No.: 32
  • 文献情報:
    Zheng, X., Chou, P.M., Mirkin, B.L. and Rebbaa, A. (2004) Senescence-initiated Reversal of Drug Resistance: Specific Role of Cathepsin L. Cancer Res. 64: 1773 - 1780.

  • 備考:
    Cell Line: Saos-2, Cell Type: Osteosarcoma, Source: Human
  • 参照:
    PubMed
  • No.: 33
  • 文献情報:
    Xie, J., Chiang, L., Contreras, J., Wu, K., Garner, J.A., Medina-Kauwe, L. and Hamm-Alvarez, S.F. (2006) Novel Fiber-Dependent Entry Mechanism for Adenovirus Serotype 5 in Lacrimal Acini. J. Virol. 80(23): 11833 - 11851.

  • 備考:
    Cell Line: Primary, Cell Type: Lacrimal Gland Acinar Cells, Source: Rabbit
  • 参照:
    PubMed
  • No.: 34
  • 文献情報:
    Yang, R., Cai, Z., Zhang, Y., Yutzy IV, W.H., Roby, K.F. and Roden, R.B.S. (2006) CD80 in Immune Suppression by Mouse Ovarian Carcinoma?Associated Gr-1+CD11b+ Myeloid Cells. Cancer Res 66 (13): 6807 - 6815.

  • 備考:
    Cell Line: Primary, Cell Type: Bone Marrow, Source: Mouse
  • 参照:
    PubMed
  • No.: 35
  • 文献情報:
    Zheng, X., Koropatnick, J., Li, M., Zhang, X., Ling, F., Ren, X., Hao, X., Sun, H., Vladau, C., Franek, J.A., Feng, B., Urquhart, B.L., Zhong, R., Freeman, D.J., Garcia, B. and Min, W-P. (2006) Reinstalling Antitumor Immunity by Inhibiting Tumor-Derived I

  • 備考:
    Cell Line: Primary, Cell Type: Dendritic Cells, Source: Mouse
  • 参照:
    PubMed
  • No.: 36
  • 文献情報:
    Zhuowei Li, Xhevahire Hyseni, Jacqueline D. Carter, Joleen M. Soukup, Lisa A. Dailey, and Yuh-Chin T. Huang (2006) Pollutant particles enhanced H2O2 production from NAD(P)H oxidase and mitochondria in human pulmonary artery endothelial cells. Am J Physiol

  • 備考:
    Cell Line: Primary, Cell Type: Pulmonary Artery Endothelium, Source: Human
  • 参照:
    PubMed
  • No.: 37
  • 文献情報:
    de Beer, M.C., Zhao, Z., Webb, N.R., van der Westhuyzen, D.R. and de Villiers, W.J.S. (2003) Lack of a direct role for macrosialin in oxidized LDL metabolism. J. Lipid Res. 44: 674 - 685.

  • 備考:
    Cell Line: RAW 264.7, Cell Type: Macrophage, Source: Mouse
  • 参照:
    PubMed
  • No.: 38
  • 文献情報:
    Ogushi, T., Takahashi, S., Takeuchi, T., Urano, T., Horie-Inoue, K., Kumagai, J., Kitamura, T., Ouchi, Y., Muramatsu, M. and Inoue, S. (2005) Estrogen Receptor-Binding Fragment-Associated Antigen 9 Is a Tumor-Promoting and Prognostic Factor for Renal Cell

  • 備考:
    Cell Line: Renca, Cell Type: Renal Cell Carcinoma, Source: Mouse
  • 参照:
    PubMed
  • No.: 39
  • 文献情報:
    Rentsendorj, O., Mirzapoiazova, T., Adyshev, D., Servinsky, L.E., Renne, T., Verin, A.D. and Pearse, D.B. (2008) Role of vasodilator-stimulated phosphoprotein in cGMP-mediated protection of human pulmonary artery endothelial barrier function. Am J Physiol

  • 備考:
    Cell Line: Primary HPAEC, Cell Type: Pulmonary Artery Endothelium, Source: Human
  • 参照:
    PubMed
  • No.: 40
  • 文献情報:
    Zheng, X., Chu, F., Chou, P.M., Gallati, C., Dier, U., Mirkin, B.L., Mousa, S.A. and Rebbaa, A. (2009) Cathepsin L inhibition suppresses drug resistance in vitro and in vivo: a putative mechanism. Am J Physiol Cell Physiol. 296(1): C65-C74.

  • 備考:
    Cell Line: SaOS2, Cell Type: Osteosarcoma, Source: Human
  • 参照:
    PubMed
  • No.: 41
  • 文献情報:
    Ueno, T., Linder, S., Na, C-L, Rice, W.R., Johansson, J., and Weaver, T.E. (2004) Processing of Pulmonary Surfactant Protein B by Napsin and Cathepsin H. J. Biol. Chem. 279: 16178-16184.

  • 備考:
    Cell Line: Primary, Cell Type: Aveolar Type II Cells, Source: Mouse
  • 参照:
    PubMed
  • No.: 42
  • 文献情報:
    Takahashi, A., Higashino, F., Aoyagi, M., Yoshida, K., Itoh, M., Kyo, S., Ohno, T., Taira, T., Ariga, H., Nakajima, K., Hatta, M., Kobayashi, M., Sano, H., Kohgo, T. and Shindoh, M., (2003) EWS/ETS Fusions Activate Telomerase in Ewings Tumors. Cancer Res

  • 備考:
    Cell Line: SCCH196, Cell Type: Sarcoma, Source: Human
  • 参照:
    PubMed
  • No.: 43
  • 文献情報:
    Song, S.W., Fuller, G.N., Zheng, H. and Zhang, W. (2005) Inactivation of the Invasion Inhibitory Gene IIp45 by Alternative Splicing in Gliomas. Cancer Res. 65(9): p. 3562-3567.

  • 備考:
    Cell Line: SNB19, Cell Type: Glioblastoma, Source: Human
  • 参照:
    PubMed
  • No.: 44
  • 文献情報:
    Zhu, S., Wang, W., Clarke, D.C. and Liu, X. (2007) Activation of Mps1 Promotes Transforming Growth Factor-??-independent Smad Signaling. J. Biol. Chem. 282(25): 18327-18338.

  • 備考:
    Cell Line: SW480, Cell Type: Colon Adenocarcinoma, Source: Human
  • 参照:
    PubMed
  • No.: 45
  • 文献情報:
    Hotulainen P. and Lappalainen, P. (2006) Stress fibers are generated by two distinct actin assembly mechanisms in motile cells J. Cell Biol. 173(3): 383-394.

  • 備考:
    Cell Line: U20S, Cell Type: Osteosarcoma, Source: Human
  • 参照:
    PubMed
  • No.: 46
  • 文献情報:
    Huang, B., Lei, Z., Zhang, G-M, Li, D., Song, C., Li, B., Liu, Y., Yuan, Y., Unkeless, J., Xiong, H. and Feng, Z-H (2008) SCF-mediated mast cell infiltration and activation exacerbate the inflammation and immunosuppression in tumor microenvironment. Blood

  • 備考:
    Cell Line: H22, Cell Type: Hepatoma, Source: Mouse
  • 参照:
    PubMed
  • No.: 47
  • 文献情報:
    Chu, F.,Chou, P.M., Zheng, X., Mirkin, B.L. and Rebbaa, A.?(2005)?Control of Multidrug Resistance Gene mdr1 and Cancer Resistance to Chemotherapy by the Longevity Gene sirt1. Cancer Res.65 (22): p. 10183-10187.

  • 備考:
    Cell Line: SaOs2, Cell Type: Osteosarcoma, Source: Human
  • 参照:
    PubMed
  • No.: 48
  • 文献情報:
    Ohyama, Y., Nifuji, A., Maeda, Y., Amagasa, T. and Noda, M. (2004) Spaciotemporal Association and Bone Morphogenetic Protein Regulation of Sclerostin and Osterix Expression during Embryonic Osteogenesis. Endocrinology. 145(10): p. 4685-4692.

  • 備考:
    Cell Line: Primary, Cell Type: Osteoblast, Source: Mouse
  • 参照:
    PubMed
  • No.: 49
  • 文献情報:
    Hu, C., Dandapat, A., Sun, L., Khan, J.A., Liu, Y., Hermonat, P.L. and Mehta, J.L. (2008) Regulation of TGFbeta 1-mediated collagen formation by LOX-1: Studies based on forced over-expression of TGFbeta 1 in wild-type and LOX-1 knockout mice cardiac fibro

  • 備考:
    Cell Line: Primary, Cell Type: Cardiac Fibroblast, Source: Mouse
  • 参照:
    PubMed
  • No.: 50
  • 文献情報:
    Juhaszova, M., Zorov, D.B., Kim, S-H, Pepe, S., Fu, O., Fishbein, K.W., Ziman, B.D., Wang, S., Ytrehus, K., Antos, C.L., Olson, E.N. and Sollott, S.J. (2004) Glycogen synthase kinase-3{beta} mediates convergence of protection signaling to inhibit the mito

  • 備考:
    Cell Line: Primary, Cell Type: Cardiac Myocytes (Neonatal), Source: Rat
  • 参照:
    PubMed
  • No.: 51
  • 文献情報:
    Kolosova, I.A., Ma, S-F, Adyshev, D.M., Wang, P., Ohba, M., Natarajan, V., Garcia, J.G.N. and Verin, A.D. (2004) Role of CPI-17 in the regulation of endothelial cytoskeleton AJP: Lung. 287(5): L970.

  • 備考:
    Cell Line: Primary, Cell Type: Lung Microvascular Endothelial Cells, Source: Human
  • 参照:
    PubMed
  • No.: 52
  • 文献情報:
    Lake, A.C. & Castellot, J.J. (2003) CCN5 modulates the antiproliferative effect of heparin and regulates cell motility in vascular smooth muscle cells. Cell Comm. & Signaling 1: 5.

  • 備考:
    Cell Line: Primary, Cell Type: Aortic Muscle Cells, Source: Rat
  • 参照:
    PubMed
  • No.: 53
  • 文献情報:
    Li, M., Qian, H., Ichim, T.E., Ge, W-W, Popov, I.A., Rycerz, K., Neu, J., White, D., Zhong, R., Min, W-P. (2004) Induction of RNA Interference in Dendritic Cells. Immunologic Research 30 (2) 215-230.

  • 備考:
    Cell Line: Primary, Cell Type: Dendritic Cells, Source: Mouse
  • 参照:
    PubMed
  • No.: 54
  • 文献情報:
    Li, M., Zhang, X., Zheng, X., Lian, D., Zhang, Z-X., Ge, W., Yang, J., Vladau, C., Suzuki, M., Chen, D., Zhong, R., Garcia, B., Jevnikar, A.M. and Min, W-P (2007) Immune Modulation and Tolerance Induction by RelB-Silenced Dendritic Cells through RNA Inter

  • 備考:
    Cell Line: Primary, Cell Type: Dendritic Cells, Source: Mouse
  • 参照:
    PubMed
  • No.: 55
  • 文献情報:
    Wu, K.Y., Hengst, U., Cox, L.J., Macosko, E.Z., Jeromin, A., Urquhart, E.R., and Jaffrey, S.R. (2005) Local translation of RhoA regulates growth cone collapse. Nature 436: 1020-1024.

  • 備考:
    Cell Line: Primary, Cell Type: Dorsal Root Ganglion, Source: Rat
  • 参照:
    PubMed
  • No.: 56
  • 文献情報:
    Numakawa, T., Nakayama, H., Suzuki, S., Kubo, T., Nara, F., Numakawa, Y., Yokomaku, D., Araki, T., Ishimoto, T., Ogura, A. and Taguchi, T. (2003) Nerve growth factor-induced glutamate release is via p75 receptor, ceramide and Ca2+ from ryanodine receptor

  • 備考:
    Cell Line: Primary, Cell Type: Cerebellar Neurons, Source: Rat
  • 参照:
    PubMed
  • No.: 57
  • 文献情報:
    Wang, Y., Chen, T., Han, C., He, D., Liu, H., An, H., Cai, Z. and Cao, X. (2007) Lysosome-associated small Rab GTPase Rab7b negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Blood 110: 962 - 971.

  • 備考:
    Cell Line: Primary, Cell Type: Macrophage, Source: Mouse
  • 参照:
    PubMed
  • No.: 58
  • 文献情報:
    Radu Stefanescu, Dustin Bassett, Rozbeh Modarresi, Francisco Santiago, Mohamad Fakruddin, and Jeffrey Laurence (2008) Synergistic interactions between interferon-{gamma} and TRAIL modulate c-FLIP in endothelial cells, mediating their lineage-specific sens

  • 備考:
    Cell Line: Primary, Cell Type: HMVEC, Source: Human
  • 参照:
    PubMed
  • No.: 59
  • 文献情報:
    Ramabadran, R. S., Chancey, A., Vallejo, J.G., Barger, P.M., Sivasubramanian, N. and Mann, D.L. (2008) Targeted Gene Silencing of Tumor Necrosis Factor Attenuates the Negative Inotropic Effects of Lipopolysaccharide in Isolated Contracting Cardiac Myocyte

  • 備考:
    Cell Line: Primary, Cell Type: Cardiac Myocytes, Source: Feline
  • 参照:
    PubMed
  • No.: 60
  • 文献情報:
    Samten, B., Howard, S.T., Weis, S.E., Wu, S., Shams, H., Townsend, J.C., Safi, H. and Barnes, P.F. (2005) Cyclic AMP Response Element-Binding Protein Positively Regulates Production of IFN-{gamma} by T Cells in Response to a Microbial Pathogen. J. Immunol

  • 備考:
    Cell Line: Primary, Cell Type: T-Cells (CD3+), Source: Human
  • 参照:
    PubMed
  • No.: 61
  • 文献情報:
    Sato, S., Xu, J., Okuyama, S., Martinez, LB., Walsh, S.M, Jacobsen, M.T, Swan, R.J., Schlautman, J.D., Ciborowski, P. and Ikezu, T. (2008) Spatial learning impairment, enhanced CDK5/p35 activity, and downregulation of NMDA receptor expression in transgeni

  • 備考:
    Cell Line: Primary, Cell Type: Cortical Neurons, Source: Mouse
  • 参照:
    PubMed
  • No.: 62
  • 文献情報:
    Smith, A.L., Ganesh, L., Leung, K., Jongstra-Bilen, J., Jongstra, J. and Nabel, G.J. (2007) Leukocyte-specific protein 1 interacts with DC-SIGN and mediates transport of HIV to the proteasome in dendritic cells. J. Exp. Med. 204(2): p. 421-430.

  • 備考:
    Cell Line: Primary, Cell Type: Dendritic Cells, Source: Human
  • 参照:
    PubMed
  • No.: 63
  • 文献情報:
    Supnet, C., Grant, J., Kong, H., Westaway, D. and Mayne, M. (2006) Amyloid ??-(1-42) Increases Ryanodine Receptor-3 Expression and Function in TgCRND8 Mice. J. Biol. Chem. 281: 38440 - 38447.

  • 備考:
    Cell Line: Primary, Cell Type: Cortical Neurons, Source: Mouse
  • 参照:
    PubMed
  • No.: 64
  • 文献情報:
    Higuchi, H., Yamashita, T., Yoshikawa, H. and Tohyama, M. (2003) Functional inhibition of the p75 receptor using a small interfering RNA. Biochem. & Biophys. Res. Comm. 301: 804809.

  • 備考:
    Cell Line: Primary, Cell Type: Schwann Cells, Source: Mouse
  • 参照:
    PubMed
  • No.: 65
  • 文献情報:
    Liu, G., Ng, H., Akasaki, Y., Yuan, X., Ehtesham, M., Yin, D., Black , K.L. and Yu, J.S. (2004) Small interference RNA modulation of IL-10 in human monocyte-derived dendritic cells enhances the Th1 response. Eur. J. Immunol. 34: 1680-1687.

  • 備考:
    Cell Line: Primary, Cell Type: Dendritic Cells, Source: Mouse
  • 参照:
    PubMed
  • No.: 66
  • 文献情報:
    Ahn, S., Wei, H., Garrison, T.R. and Lefkowitz, R.J. (2004) Reciprocal Regulation of Angiotensin Receptor-activated Extracellular Signal-regulated Kinases by (beta)-Arrestins 1 and 2. J. Biol. Chem. 279: 7807-7811.

  • 備考:
    Cell Line: HEK 293, Cell Type: Embryonic Kidney, Source: Human
  • 参照:
    PubMed
  • No.: 67
  • 文献情報:
    Ren, J., Shi, M., Liu, R., Yang, Q-H., Johnson, T., Skarnes, W.C. and Du, C. (2005) The Birc6 (Bruce) gene regulates p53 and the mitochondrial pathway of apoptosis and is essential for mouse embryonic development. Proc. Natl. Acad. Sci. USA. 102(3): p. 56

  • 備考:
    Cell Line: H460, Cell Type: Lung Cancer, Source: Human
  • 参照:
    PubMed
  • No.: 68
  • 文献情報:
    Saotome, M., Safiulina, D., Szabadkai, G., Das, S., Fransson, A., Aspenstrom, P., Rizzuto, R. and Hajnoczky, G. (2008) Bidirectional Ca2+-dependent control of mitochondrial dynamics by the Miro GTPase. Proc Natl Acad Sci U S A 105(52): p. 20728.

  • 備考:
    Cell Line: H9c2, Cell Type: Myoblast, Source: Rat
  • 参照:
    PubMed
  • No.: 69
  • 文献情報:
    Huang, W., Eum, S.Y., Andras, I.E., Hennig, B. and Toborek, M. (2009) PPAR{alpha} and PPAR{gamma} attenuate HIV-induced dysregulation of tight junction proteins by modulations of matrix metalloproteinase and proteasome activities. FASEB J 13 Jan 2009.

  • 備考:
    Cell Line: hCMEC/D3, Cell Type: Brain Microvascular Endothelia, Source: Human
  • 参照:
    PubMed
  • No.: 70
  • 文献情報:
    Yao, K., Shida, S., Selvakumaran, M., Zimmerman, R., Simon, E., Schick, J., Haas, N.B., Balke, M., Ross, H., Johnson, S.W. and O"Dwyer, P.J. (2005) Macrophage Migration Inhibitory Factor Is a Determinant of Hypoxia-Induced Apoptosis in Colon Cancer Cell L

  • 備考:
    Cell Line: HCP40, Cell Type: Colon adenocarcinoma, Source: null
  • 参照:
    PubMed
  • No.: 71
  • 文献情報:
    Wang, J., Rajput, A., Kan, J.L.C., Rose, R., Liu, X., Kuropatwinski, K., Hauser, J., Beko, A., Dominquez, I., Sharratt, E.A., Brattain, L., LeVea, C., Sun, F., Keane, D.M., Gibson, N.W. and Michael G. Brattain (2009) Knockdown of Ron kinase inhibits mutan

  • 備考:
    Cell Line: HCT-116, Cell Type: Colon Carcinoma, Source: Human
  • 参照:
    PubMed
  • No.: 72
  • 文献情報:
    Yao, K., Shida, S., Selvakumaran, M., Zimmerman, R., Simon, E., Schick, J., Haas, N.B. Balke, M., Ross, H., Johnson, S.W. and O"Dwyer, P.J. (2005) Macrophage Migration Inhibitory Factor Is a Determinant of Hypoxia-Induced Apoptosis in Colon Cancer Cell Li

  • 備考:
    Cell Line: HCT-116, Cell Type: Colon Adenocarcinoma, Source: Human
  • 参照:
    PubMed
  • No.: 73
  • 文献情報:
    Shikama, Y., Yamada, M., Miyashita, T. (2004) Caspase-8 and caspase-10 activate NF-B through RIP, NIK and IKK kinases. Eur. J. Immun. 33 (7): 1998-2006.

  • 備考:
    Cell Line: HEK 293, Cell Type: Embryonic Kidney, Source: Human
  • 参照:
    PubMed
  • No.: 74
  • 文献情報:
    Ahn, S., Shenoy, S.K., Wei, H. and Lefkowitz, R.J. (2004) Differential Kinetic and Spatial Patterns of {beta}-Arrestin and G Protein-mediated ERK Activation by the Angiotensin II Receptor. J. Biol. Chem. 279 (34): 35518-35525.

  • 備考:
    Cell Line: HEK 293, Cell Type: Embryonic Kidney, Source: Human
  • 参照:
    PubMed
  • No.: 75
  • 文献情報:
    Jing, H., Yen, J-H and Ganea, D. (2004) A novel signaling pathway mediates the inhibition of CCL3/4 expression by PGE2. J. Biol. Chem. 279(53): p. 55176-55186.

  • 備考:
    Cell Line: DC2.4, Cell Type: Bone Marrow, Source: Mouse
  • 参照:
    PubMed
  • No.: 76
  • 文献情報:
    Kim, J., Ahn, S., Ren, X-R., Whalen, E.J., Reiter, E., Wei, H. and Lefkowitz, R.J. (2005) Functional antagonism of different G protein-coupled receptor kinases for {beta}-arrestin-mediated angiotensin II receptor signaling. Proc. Natl. Acad. Sci.?102: 144

  • 備考:
    Cell Line: HEK 293, Cell Type: Embryonic Kidney, Source: Human
  • 参照:
    PubMed
  • No.: 77
  • 文献情報:
    Kohout, T.A., Nicholas, S.L., Perry, S.J., Reinhart, G., Junger, S. and Struthers, R. (2004) Differential Desensitization, Receptor Phosphorylation, {beta}-Arrestin Recruitment, and ERK1/2 Activation by the Two Endogenous Ligands for the CC Chemokine Rece

  • 備考:
    Cell Line: HEK 293, Cell Type: Embryonic Kidney, Source: Human
  • 参照:
    PubMed
  • No.: 78
  • 文献情報:
    Liang, Y., Yu, W., Li, Y., Yan, X., Huang, Q. and Zhu, X. (2004) Nudel functions in membrane traffic mainly through association with Lis1 and cytoplasmic dynein. J. Cell Biol. 164 (4): 557-566.

  • 備考:
    Cell Line: HEK 293, Cell Type: Embryonic Kidney, Source: Human
  • 参照:
    PubMed
  • No.: 79
  • 文献情報:
    Ren, X-R., Reiter, E., Ahn, S., Kim, J., Chen, W. and Lefkowitz, R.J. (2005) Different G protein-coupled receptor kinases govern G protein and {beta}-arrestin-mediated signaling of V2 vasopressin receptor. Proc. Natl. Acad. Sci. 102: 1448 - 1453.

  • 備考:
    Cell Line: HEK 293, Cell Type: Embryonic Kidney, Source: Human
  • 参照:
    PubMed
  • No.: 80
  • 文献情報:
    Zhang, Y-A., Nemunaitis, J., Samuel, S.K., Chen, P., Shen, Y. and Tong, A.W. (2006) Antitumor Activity of an Oncolytic Adenovirus-Delivered Oncogene Small Interfering RNA. Cancer Res. 66(19): 9736-9743.

  • 備考:
    Cell Line: H441, Cell Type: Lung Adenocarcinoma, Source: Human
  • 参照:
    PubMed
  • No.: 81
  • 文献情報:
    Ahn, S., Nelson, C.D., Garrison, T.R., Miller, W.E. and Lefkowitz, R.J. (2003) Desensitization, internalization, and signaling functions of -arrestins demonstrated by RNA interference. Proc. Natl. Acad. Sci. 100: 1740 - 1744.

  • 備考:
    Cell Line: HEK 293, Cell Type: Embryonic Kidney, Source: Human
  • 参照:
    PubMed
  • No.: 82
  • 文献情報:
    Mizuarai, S., Miki, S., Araki, H., Takahashi, K. and Kotani, H.(2005) Identification of Dicarboxylate Carrier Slc25a10 as Malate Transporter in de Novo Fatty Acid Synthesis. J. Biol. Chem.280(37): p. 32434-32441.

  • 備考:
    Cell Line: 3T3-L1, Cell Type: Embryo, Source: Swiss Mouse
  • 参照:
    PubMed
  • No.: 83
  • 文献情報:
    Ito, K., Yamamura, S., Essilfie-Quaye, S., Cosio, B., Ito, M., Barnes, P.J. and Adcock, I.M. (2006) Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF??B suppression. J. Exp. Med. 203(1): 7-13.

  • 備考:
    Cell Line: A549, Cell Type: Lung Carcinoma, Source: Human
  • 参照:
    PubMed
  • No.: 84
  • 文献情報:
    Stepulak, A., Sifringer, M., Rzeski, W., Endesfelder, S., Gratopp, A., Pohl, E.E., Bittigau, P., Hansen, H.H., Stryjecka-Zimmer, M., Turski, L. and Ikonomidou, C. (2005) NMDA antagonist inhibits the extracellular signal-regulated kinase pathway and suppre

  • 備考:
    Cell Line: A549, Cell Type: Lung Carcinoma, Source: Human
  • 参照:
    PubMed
  • No.: 85
  • 文献情報:
    Varro, A., Noble, P-J. M., Pritchard, D.M., Kennedy, S., Hart, C.A., Dimaline, R. and Dockray, G.J. (2004) Helicobacter pylori Induces Plasminogen Activator Inhibitor 2 in Gastric Epithelial Cells through Nuclear Factor-B and RhoA: Implications for Invasi

  • 備考:
    Cell Line: AGS, Cell Type: Gastric Epithelium, Source: Human
  • 参照:
    PubMed
  • No.: 86
  • 文献情報:
    Huang, B., Zhao, J., Shen, S., Li, H., He, K-L, Shen, G-X, Mayer, L., Unkeless, J., Li, D., Yuan, Y., Zhang, G.-M., Xiong, H. and Feng, Z.-H. (2007) Listeria monocytogenes Promotes Tumor Growth via Tumor Cell Toll-Like Receptor 2 Signaling. Cancer Res. 67

  • 備考:
    Cell Line: H22, Cell Type: Hepatoma, Source: Mouse
  • 参照:
    PubMed
  • No.: 87
  • 文献情報:
    Liang, X-J, Finkel, T., Shen, D-W, Yin, J-J, Aszalos, A. and Gottesman, M.M. (2008) SIRT1 Contributes in Part to Cisplatin Resistance in Cancer Cells by Altering Mitochondrial Metabolism. Mol Cancer Res 6(9): 1499-506.

  • 備考:
    Cell Line: GS-KB-3-1, Cell Type: Epidermoid Adenocarcinoma, Source: Human
  • 参照:
    PubMed
  • No.: 88
  • 文献情報:
    Nunes, R.O., Schmidt, M., Dueck, G., Baarsma, H., Halayko, A.J., Kerstjens, H.A.M., Meurs, H. and Gosens, R. (2008) GSK-3/??-catenin signaling axis in airway smooth muscle: role in mitogenic signaling Am J Physiol Lung Cell Mol Physiol. 294: L1110 - L1118

  • 備考:
    Cell Line: Bronchial, Cell Type: Smooth Muscle, Source: Human
  • 参照:
    PubMed
  • No.: 89
  • 文献情報:
    Zhou, X., Stuart, A., Dettin, L.E., Rodriguez, G., Hoel, B. and Gallicano G.I. (2004) Desmoplakin is required for microvascular tube formation in culture. J. Cell Sci. 117: 3129-3140.

  • 備考:
    Cell Line: C166, Cell Type: Yolk Sack Endothelium, Source: Mouse
  • 参照:
    PubMed
  • No.: 90
  • 文献情報:
    Evangelisti, C., Tazzari, P.L., Riccio, M., Fiume, R., Hozumi, Y., Fala, F., Goto, K.., Manzoli, L., Cocco, L. and Martelli, A.M. (2007) Nuclear diacylglycerol kinase-?? is a negative regulator of cell cycle progression in C2C12 mouse myoblasts. FASEB J.

  • 備考:
    Cell Line: C2C12, Cell Type: Myoblast, Source: Mouse
  • 参照:
    PubMed
  • No.: 91
  • 文献情報:
    Saarikangas, J., Hakanen, J., Mattila, P.K., Grumet, M., Salminen, M. and Lappalainen, P. (2008) ABBA regulates plasma-membrane and actin dynamics to promote radial glia extension. J Cell Sci. 121(Pt 9):1444-54.

  • 備考:
    Cell Line: C6R, Cell Type: Glioma, Source: Rat
  • 参照:
    PubMed
  • No.: 92
  • 文献情報:
    Kheifets, V., Bright, R., Inagaki, K., Schechtman, D. and Mochly-Rosen, D. (2006) Protein Kinase C ?? PKC-Annexin V Interaction: a required step in ?? PKC translocation and function. J. Biol. Chem. 281(32): p. 23218-23226.

  • 備考:
    Cell Line: CHO-K1, Cell Type: Ovary, Source: Chinese Hamster
  • 参照:
    PubMed
  • No.: 93
  • 文献情報:
    Wei, H., Ahn, S., Barnes, W.G. and Lefkowitz, R.J., (2004) Stable interaction between beta -arrestin2 and AT 1A receptor is required for beta -arrestin2 mediated activation of extracellular signal-regulated kinase 1 and 2. J. Biol. Chem. 279: 48255-48261.

  • 備考:
    Cell Line: HEK 293, Cell Type: Embryonic Kidney, Source: Human
  • 参照:
    PubMed
  • No.: 94
  • 文献情報:
    Tran, T., Ens-Blackie, K., Rector, E.S., Stelmack, G.L., McNeill, K.D., Tarone, G., Gerthoffer, W.T., Unruh, H. and Halayko, A.J. (2007) Laminin-binding Integrin ??7 is Required for Contractile Phenotype Expression by Human Airway Myocyte. Am. J. Respir.

  • 備考:
    Cell Line: ASM Transformed, Cell Type: Airway Smooth Muscle Cells, Source: Human
  • 参照:
    PubMed
  • No.: 95
  • 文献情報:
    Pastorino, J.G. and Shulga, N. (2008) TNFalpha can provoke cleavage and activation of sterol regulatory element binding protein in ethanol exposed cells via a caspase dependent pathway that is cholesterol-insensitive. J. Biol. Chem. 283: 25638 - 25649.

  • 備考:
    Cell Line: HepG2, Cell Type: Hepatocellular Carcinoma, Source: Human
  • 参照:
    PubMed
  • No.: 96
  • 文献情報:
    Chung, J-S., Sato, K., Dougherty, I.I., Cruz, Jr., P.D. and Ariizumi, K. (2007) DC-HIL is a negative regulator of T lymphocyte activation. Blood. 109(10): p. 4320-4327.

  • 備考:
    Cell Line: HeLa, Cell Type: Cervical Carcinoma, Source: Human
  • 参照:
    PubMed
  • No.: 97
  • 文献情報:
    Kheifets, V., Bright, R., Inagaki, K., Schechtman, D. and Mochly-Rosen, D. (2006) Protein Kinase C ??}PKC)-Annexin V Interaction: a required step in ?? PKC translocation and function. J. Biol. Chem. 281(32): p. 23218-23226.

  • 備考:
    Cell Line: HeLa, Cell Type: Cervical Carcinoma, Source: Human
  • 参照:
    PubMed
  • No.: 98
  • 文献情報:
    Layzer, J.M., McCaffrey, A.P., Tanner, A.K., Huang, Zan, Kay, Mark A. and Sullenger, B.A. (2004) In vivo activity of nuclease-resistant siRNAs. RNA 10 (5): p. 766-771.

  • 備考:
    Cell Line: HeLa, Cell Type: Cervical Carcinoma, Source: Human
  • 参照:
    PubMed
  • No.: 99
  • 文献情報:
    Pomerening, J.R., Ubersax, J.A. and Ferrell, J.E., Jr. (2008) Rapid Cycling and Precocious Termination of G1 Phase in Cells Expressing CDK1AF. Mol. Biol. Cell, 19: 3426 - 3441.

  • 備考:
    Cell Line: HeLa, Cell Type: Cervical Carcinoma, Source: Human
  • 参照:
    PubMed
  • No.: 100
  • 文献情報:
    Shulga, N. and Pastorino, J.G. (2006) Acyl Coenzyme A-binding Protein Augments Bid-induced Mitochondrial Damage and Cell Death by Activating ??-Calpain. J. Biol. Chem. 281(41): 30824-30833.

  • 備考:
    Cell Line: HeLa, Cell Type: Cervical Carcinoma, Source: Human
  • 参照:
    PubMed
  • No.: 101
  • 文献情報:
    Witherow, D.S., Garrison, T.R., Miller, W.E. and Robert J. Lefkowitz (2004) {beta}-Arrestin inhibits NF-{kappa}B activity by means of its interaction with the NF-{kappa}B inhibitor I{kappa}B{alpha}. Proc. Natl. Acad. Sci. USA 101: 8603-8607.

  • 備考:
    Cell Line: HeLa, Cell Type: Cervical Carcinoma, Source: Human
  • 参照:
    PubMed
  • No.: 102
  • 文献情報:
    Shenoy, S.K., Drake, M.T., Nelson, C.D., Houtz, D.A., Xiao, K., Madabushi, S., Reiter, E., Premont, R.T., Lichtarge, O. and Lefkowitz, R.J. (2006) {beta}-Arrestin-dependent, G Protein-independent ERK1/2 Activation by the {beta}2 Adrenergic Receptor. J. Bi

  • 備考:
    Cell Line: HEK 293, Cell Type: Embryonic Kidney, Source: Human
  • 参照:
    PubMed
  • No.: 103
  • 文献情報:
    Zhu, S., Wang, W., Clarke, D.C. and Liu, X. (2007) Activation of Mps1 Promotes Transforming Growth Factor-??-independent Smad Signaling. J. Biol Chem. 282 (25) 18327-18338.

  • 備考:
    Cell Line: HeLa, Cell Type: Cervical Carcinoma, Source: Human
  • 参照:
    PubMed
  • No.: 104
  • 文献情報:
    Violin, J.D., DeWire, S.M., Barnes, W.G. and Lefkowitz, R.J. (2006) G Protein-Coupled Receptor Kinase and ??-arrestin mediated desensitization of the angiotensin II type 1A receptor elucidated by diacylgylcerol dynamics. J. Biol. Chem. 281: 36411 - 36419.

  • 備考:
    Cell Line: HEK-293, Cell Type: Embryonic Kidney, Source: Human
  • 参照:
    PubMed
  • No.: 105
  • 文献情報:
    Smirnova, I.V., Kajstura, M., Sawamura, T. and Goligorsky, M.S. (2004) Asymmetric dimethylarginine upregulates LOX-1 in activated macrophages: role in foam cell formation. AJP: Heart 287(2): p. H782-H790

  • 備考:
    Cell Line: HL-60, Cell Type: Peripheral Blood Promyelocytic Leukemia, Source: Human
  • 参照:
    PubMed
  • No.: 106
  • 文献情報:
    Berdyshev, E.V., Gorshkova, I., Skobeleva, A., Bittman, R., Lu, X., Dudek, S.M., Mirzapoiazova, T., Garcia, J.G.N. and Natarajan, V. (2009) FTY720 inhibits ceramide synthases and upregulates dihydrosphingosine-1-phosphate formation in human lung endotheli

  • 備考:
    Cell Line: HPAEC, Cell Type: Pulmonary Artery Endothelium, Source: Human
  • 参照:
    PubMed
  • No.: 107
  • 文献情報:
    Maneechotesuwan, K., Xin, Y., Ito, K., Jazrawi, E., Lee, K-Y., Usmani, O.S., Barnes, P.J. and Adcock, I.M. (2007) Regulation of Th2 Cytokine Genes by p38 MAPK-Mediated Phosphorylation of GATA-3. J. Immunol. 178(4): 2491-2498.

  • 備考:
    Cell Line: HUT-78, Cell Type: T Cells, Source: Human
  • 参照:
    PubMed
  • No.: 108
  • 文献情報:
    Abboud-Jarrous, G., Atzmon, R., Peretz, T., Palermo, C., Gadea, B.B., Joyce, J.A. and Vlodavsky, I. (2008) Cathepsin L Is Responsible for Processing and Activation of Proheparanase through Multiple Cleavages of a Linker Segment. J. Biol. Chem. 283: 18167

  • 備考:
    Cell Line: JAR, Cell Type: Choriocarcinoma, Source: Human
  • 参照:
    PubMed
  • No.: 109
  • 文献情報:
    Yang, Q-H, Church-Hajduk, R., Ren, J., Newton, M.L. and Du, C. (2003) Omi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosis. Genes & Dev. 17: 1487 - 1496.

  • 備考:
    Cell Line: HeLa, Cell Type: Cervical Carcinoma, Source: Human
  • 参照:
    PubMed
  • No.: 110
  • 文献情報:
    IM Kim, DG Tilley, J Chen, NC Salazar, EJ Whalen, JD Violin, and HA Rockman (2008) Beta-blockers alprenolol and carvedilol stimulate beta-arrestin-mediated EGFR transactivation. Proc Natl Acad Sci 105(38): 14555-60.

  • 備考:
    Cell Line: HEK-293, Cell Type: Embryonic Kidney, Source: Human
  • 参照:
    PubMed
  • No.: 111
  • 文献情報:
    Wei, H., Ahn, S., Shenoy, S.K., Karnik, S.S., Hunyady, L., Luttrell, L.M. and Lefkowitz, R.J. (2003) Independent -arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2. Proc. Natl. Acad.

  • 備考:
    Cell Line: HEK 293, Cell Type: Embryonic Kidney, Source: Human
  • 参照:
    PubMed
  • No.: 112
  • 文献情報:
    Wu, J-H, Goswami, R., Kim, L.K., Miller, W.E., Peppel, K. and Freedman, N.J. (2005) The Platelet-derived Growth Factor Receptor-{beta} Phosphorylates and Activates G Protein-coupled Receptor Kinase-2: a Mechanism for Feedback Inhibition. J. Biol. Chem. 28

  • 備考:
    Cell Line: HEK 293, Cell Type: Embryonic Kidney, Source: Human
  • 参照:
    PubMed
  • No.: 113
  • 文献情報:
    Ahn, S., Kim, J., Hara, M.R., Ren, X. and Lefkowitz, R.J. (2009) ?? -arrestin2 mediates anti-apoptotic signaling through regulation of bad phosphorylation. J Biol Chem 284(13): 8855-65.

  • 備考:
    Cell Line: HEK-293, Cell Type: Embryonic Kidney, Source: Human
  • 参照:
    PubMed
  • No.: 114
  • 文献情報:
    Barthet, G., Framery, B., Gaven, F., Pellissier, L., Reiter, E., Claeysen, S., Bockaert, J. and Dumuis, A. (2007) 5-Hydroxytryptamine 4 Receptor Activation of the Extracellular Signal-regulated Kinase Pathway Depends on Src Activation but Not on G Protein

  • 備考:
    Cell Line: HEK-293, Cell Type: Embryonic Fibroblast, Source: Human
  • 参照:
    PubMed
  • No.: 115
  • 文献情報:
    El-Shewy, H.M., Johnson, K.R., Lee, M-H, Jaffa, A.A., Obeid, L.M. and Luttrell, L.M. (2006) Insulin-like Growth Factors Mediate Heterotrimeric G Protein-dependent ERK1/2 Activation by Transactivating Sphingosine 1-Phosphate Receptors . J. Biol. Chem. 281(

  • 備考:
    Cell Line: HEk-293, Cell Type: Embryonic Kidney, Source: Human
  • 参照:
    PubMed
  • No.: 116
  • 文献情報:
    Cassimeris, L. and Morabito, J. (2004) TOGp, the Human Homolog of XMAP215/Dis1, Is Required for Centrosome Integrity, Spindle Pole Organization, and Bipolar Spindle Assembly. Mol. Biol. Cell 15 (4): 1580-1590.

  • 備考:
    Cell Line: HeLa, Cell Type: Cervical Carcinoma, Source: Human
  • 参照:
    PubMed
  • No.: 117
  • 文献情報:
    Gesty-Palmer, D., Chen, M., Reiter, E., Ahn, S., Nelson, C.D., Wang, S., Eckhardt, A.E., Cowan, C.L., Spurney, R.F., Luttrell, L.M. and Lefkowitz, R.J. (2006) Distinct beta-Arrestin- and G Protein-dependent Pathways for Parathyroid Hormone Receptor-stimul

  • 備考:
    Cell Line: HEK-293, Cell Type: Embryonic Kidney, Source: Human
  • 参照:
    PubMed
  • No.: 118
  • 文献情報:
    Bentley, A.M., Normand, G., Hoyt, J. and King, R.W. (2007) Distinct Sequence Elements of Cyclin B1 Promote Localization to Chromatin, Centrosomes, and Kinetochores during Mitosis. Mol. Biol. Cell, Dec 2007; 18: 4847 - 4858.

  • 備考:
    Cell Line: HeLa, Cell Type: Cervical Carcinoma, Source: Human
  • 参照:
    PubMed
  • No.: 119
  • 文献情報:
    Kani, S., Nakayama, E., Yoda, A., Onishi, N., Sougawa, N., Hazaka, Y., Umeda, T., Takeda, K., Ichijo, H., Hamada, Y. and Minami, Y. (2007) Chk2 kinase is required for methylglyoxal-induced G2/M cell-cycle checkpoint arrest: implication of cell-cycle check

  • 備考:
    Cell Line: HEK-293, Cell Type: Embryonic Kidney, Source: Human
  • 参照:
    PubMed
  • No.: 120
  • 文献情報:
    Kara, E., Crepieux, P., Gauthier, C., Martinat, N., Piketty, V., Guillou, F., and Reiter, E. (2006) A Phosphorylation Cluster of Five Serine and Threonine Residues in the C-Terminus of the Follicle-Stimulating Hormone Receptor Is Important for Desensitiza

  • 備考:
    Cell Line: HEk-293, Cell Type: Embryonic Kidney, Source: Human
  • 参照:
    PubMed
  • No.: 121
  • 文献情報:
    Nelson, C.D., Kovacs, J.J., Nobles, K.N., Whalen, E.J. and Lefkowitz, R.J. (2008) ??-Arrestin Scaffolding of Phosphatidylinositol 4-Phosphate 5-Kinase I?? Promotes Agonist-stimulated Sequestration of the {beta}2-Adrenergic Receptor. J. Biol. Chem. 283(30)

  • 備考:
    Cell Line: HEK-293, Cell Type: Embryonic Kidney, Source: Human
  • 参照:
    PubMed
  • No.: 122
  • 文献情報:
    Noma, T., Lemaire, A., Prasad, S.V.N., Barki-Harrington, L., Tilley, D.G., Chen, J., Le Corvoisier, P., Violin, J.D., Wei, H., Lefkowitz, R.J. and Rockman, H.A. (2007) ??-Arrestin mediated ??1-adrenergic receptor transactivation of the EGFR confers cardio

  • 備考:
    Cell Line: HEK-293, Cell Type: Embryonic Kidney, Source: Human
  • 参照:
    PubMed
  • No.: 123
  • 文献情報:
    Rajagopal, K., Whalen, E.J., Violin, J.D., Stiber, J.A., Rosenberg, P.B., Premont, R.T., Coffman, T.M., Rockman, H.A. and Lefkowitz, R.J. (2006) ??-Arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes. P

  • 備考:
    Cell Line: HEk-293, Cell Type: Embryonic Kidney, Source: Human
  • 参照:
    PubMed
  • No.: 124
  • 文献情報:
    Shenoy, S.K., Xiao, K., Venkataramanan, V., Snyder, P.M., Freedman, N.J. and Weissman, A.M. (2008) NEDD4 mediates agonist-dependent ubiquitination, lysosomal targeting and degradation of the beta 2 adrenergic receptor. J. Biol. Chem. 283: 22166 - 22176.

  • 備考:
    Cell Line: HEK-293, Cell Type: Embryonic Kidney, Source: Human
  • 参照:
    PubMed
  • No.: 125
  • 文献情報:
    Nguyen, J.T. and Wells, J.A. (2003) Direct activation of the apoptosis machinery as a mechanism to target cancer cells. Proc. Natl. Acad. Sci. 100: 7533  7538.

  • 備考:
    Cell Line: Jurkat, Cell Type: T-Cell Lymphoma, Source: Human
  • 参照:
    PubMed
  • No.: 126
  • 文献情報:
    El-Shewy, H.M., Lee, M-H., Obeid, L.M., Jaffa, A.A. and Luttrell, L.M. (2007) The Insulin-like Growth Factor Type 1 and Insulin-like Growth Factor Type 2/Mannose-6-phosphate Receptors Independently Regulate ERK1/2 Activity in HEK293 Cells. J. Biol. Chem.

  • 備考:
    Cell Line: HEK-293, Cell Type: Embryonic Kidney, Source: Human
  • 参照:
    PubMed
  • No.: 127
  • 文献情報:
    Qu H et al. miRNA-558 promotes tumorigenesis and aggressiveness of neuroblastoma cells through activating the transcription of heparanase. Hum. Mol. Genet. 2015 May;24(9):2539-51
    Qu H et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 128
  • 文献情報:
    Jean-Charles PY et al. Ubiquitin-specific Protease 20 Regulates the Reciprocal Functions of β-Arrestin2 in Toll-like Receptor 4-promoted Nuclear Factor κB (NFκB) Activation. J. Biol. Chem. 2016 Apr;291(14):7450-64
    Jean-Charles PY et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 129
  • 文献情報:
    Lorin C et al. Dystrophic cardiomyopathy: role of TRPV2 channels in stretch-induced cell damage. Cardiovasc. Res. 2015 Apr;106(1):153-62
    Lorin C et al
    2015/01/01
  • 備考:
  • 参照:
    PubMed