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在庫・価格 : 2024年03月29日 10時11分 現在

商品名 商品コード メーカー 包装 価格 在庫 リスト
m6A RNA Methylation Quantification Kit, Colorimetric, EpiQuik(48 reactions)
データシート
P-9005-48 EPGエピジェンテックグループ
Epigentek Group Inc.
1 kit ¥85,000
(未発注)
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在庫・価格 : 2024年03月29日 10時11分 現在

m6A RNA Methylation Quantification Kit, Colorimetric, EpiQuik(48 reactions)

  • 商品コード:P-9005-48
  • メーカー:EPG
  • 包装:1kit
  • 価格: ¥85,000
  • 在庫:無(未発注)
使用文献
No. 文献情報 備考 参照
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2 Zhang C et al. Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m6A-demethylation of NANOG mRNA. Proc. Natl. Acad. Sci. U.S.A. 2016 Apr;113(14):E2047-56
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3 Zhang C et al. Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells. Oncotarget 2016 Aug;
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4 Yin H et al. Electrochemical immunosensor for N6-methyladenosine detection in human cell lines based on biotin-streptavidin system and silver-SiO2 signal amplification. Biosens Bioelectron 2017 Apr;90:494-500
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5 Lewinska A et al. Downregulation of methyltransferase Dnmt2 results in condition-dependent telomere shortening and senescence or apoptosis in mouse fibroblasts. J. Cell. Physiol. 2017 Dec;232(12):3714-3726
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6 Walters BJ et al. The Role of The RNA Demethylase FTO (Fat Mass and Obesity-Associated) and mRNA Methylation in Hippocampal Memory Formation. Neuropsychopharmacology 2017 Jun;42(7):1502-1510
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7 Slobodin B et al. Transcription Impacts the Efficiency of mRNA Translation via Co-transcriptional N6-adenosine Methylation. Cell 2017 Apr;169(2):326-337.e12
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8 Elkashef SM et al. IDH Mutation, Competitive Inhibition of FTO, and RNA Methylation. Cancer Cell 2017 05;31(5):619-620
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9 Lewinska A et al. Reduced levels of methyltransferase DNMT2 sensitize human fibroblasts to oxidative stress and DNA damage that is accompanied by changes in proliferation-related miRNA expression. Redox Biol 2017 Aug;14:20-34
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10 Lewinska A et al. Sulforaphane-Induced Cell Cycle Arrest and Senescence are accompanied by DNA Hypomethylation and Changes in microRNA Profile in Breast Cancer Cells. Theranostics 2017;7(14):3461-3477
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11 Zhou S et al. FTO regulates the chemo-radiotherapy resistance of cervical squamous cell carcinoma (CSCC) by targeting β-catenin through mRNA demethylation. Mol. Carcinog. 2018 05;57(5):590-597
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12 Ding C et al. Increased N6-methyladenosine causes infertility is associated with FTO expression. J. Cell. Physiol. 2018 Sep;233(9):7055-7066
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13 Lu N et al. Curcumin Attenuates Lipopolysaccharide-Induced Hepatic Lipid Metabolism Disorder by Modification of m<sup>6</sup> A RNA Methylation in Piglets. Lipids 2018 01;53(1):53-63
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14 Feng Z et al. METTL3 regulates alternative splicing of MyD88 upon the lipopolysaccharide-induced inflammatory response in human dental pulp cells. J. Cell. Mol. Med. 2018 May;22(5):2558-2568
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15 Gu S et al. N<sup>6</sup>-methyladenosine mediates the cellular proliferation and apoptosis via microRNAs in arsenite-transformed cells. Toxicol. Lett. 2018 Aug;292:1-11
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16 Dai T et al. Analogous modified DNA probe and immune competition method-based electrochemical biosensor for RNA modification. Biosens Bioelectron 2018 Aug;114:72-77
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17 Faulds KJ et al. Glycogen synthase kinase-3 (GSK-3) activity regulates mRNA methylation in mouse embryonic stem cells. J. Biol. Chem. 2018 07;293(27):10731-10743
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18 Du J et al. The regulation of skeletal muscle fiber-type composition by betaine is associated with NFATc1/MyoD. J. Mol. Med. 2018 Jul;96(7):685-700
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19 Guo J et al. Deregulation of UBE2C-mediated autophagy repression aggravates NSCLC progression. Oncogenesis 2018 Jun;7(6):49
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20 Panneerdoss S et al. Cross-talk among writers, readers, and erasers of m<sup>6</sup>A regulates cancer growth and progression. Sci Adv 2018 10;4(10):eaar8263
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21 Chen H et al. Changes of RNA N<sup>6</sup>-methyladenosine in the hormesis effect induced by arsenite on human keratinocyte cells. Toxicol In Vitro 2019 Apr;56:84-92
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22 Rong B et al. Reduced delivery of epididymal adipocyte-derived exosomal resistin is essential for melatonin ameliorating hepatic steatosis in mice. J. Pineal Res. 2019 May;66(4):e12561
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23 Song H et al. METTL3 and ALKBH5 oppositely regulate m<sup>6</sup>A modification of <i>TFEB</i> mRNA, which dictates the fate of hypoxia/reoxygenation-treated cardiomyocytes. Autophagy 2019 Aug;15(8):1419-1437
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24 Wang Y et al. Genome-wide screening of altered m6A-tagged transcript profiles in the hippocampus after traumatic brain injury in mice. Epigenomics 2019 May;11(7):805-819
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25 Nettersheim D et al. N6-Methyladenosine detected in RNA of testicular germ cell tumors is controlled by METTL3, ALKBH5, YTHDC1/F1/F2, and HNRNPC as writers, erasers, and readers. Andrology 2019 Jul;7(4):498-506
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26 Wu L et al. Changes of N6-methyladenosine modulators promote breast cancer progression. BMC Cancer 2019 Apr;19(1):326
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27 Fukumoto T et al. N<sup>6</sup>-Methylation of Adenosine of <i>FZD10</i> mRNA Contributes to PARP Inhibitor Resistance. Cancer Res. 2019 Jun;79(11):2812-2820
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28 Niu Y et al. RNA N6-methyladenosine demethylase FTO promotes breast tumor progression through inhibiting BNIP3. Mol. Cancer 2019 03;18(1):46
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29 Zhao T et al. Oxidative stress: One potential factor for arsenite-induced increase of N<sup>6</sup>-methyladenosine in human keratinocytes. Environ. Toxicol. Pharmacol. 2019 Jul;69:95-103
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30 Zhu H et al. ALKBH5 inhibited autophagy of epithelial ovarian cancer through miR-7 and BCL-2. J. Exp. Clin. Cancer Res. 2019 Apr;38(1):163
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31 Heng J et al. Maternal heat stress regulates the early fat deposition partly through modification of m<sup>6</sup>A RNA methylation in neonatal piglets. Cell Stress Chaperones 2019 May;24(3):635-645
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32 Liu Q et al. METTL3 promotes experimental osteoarthritis development by regulating inflammatory response and apoptosis in chondrocyte. Biochem. Biophys. Res. Commun. 2019 Aug;516(1):22-27
Liu Q et al
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PubMed
33 Kwon J et al. Functional roles of hnRNPA2/B1 regulated by METTL3 in mammalian embryonic development. Sci Rep 2019 Jun;9(1):8640
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PubMed
34 Liu T et al. Dysregulated N6-methyladenosine&#xA0;methylation writer METTL3 contributes to the proliferation and migration of gastric cancer. J. Cell. Physiol. 2019 Jun;
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PubMed
35 Xu Y et al. The N6-methyladenosine mRNA methylase METTL14 promotes renal ischemic reperfusion injury via suppressing YAP1. J. Cell. Biochem. 2019 Jul;
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PubMed
36 Zhang S et al. m<sup>6</sup>A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program. Cancer Cell 2017 04;31(4):591-606.e6
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37 Ishihara Y et al. Hsa-miR-520d-5p promotes survival in human dermal fibroblasts exposed to a lethal dose of UV irradiation. NPJ Aging Mech Dis 2016;2:16029
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38 Wang H et al. A sensitive photoelectrochemical immunoassay of N<sup>6</sup>-methyladenosine based on dual-signal amplification strategy: Ru doped in SiO<sub>2</sub> nanosphere and carboxylated g-C<sub>3</sub>N<sub>4</sub>. Biosens Bioelectron 2018 Jan;99:
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39 Schroeder M et al. Sex dependent impact of gestational stress on predisposition to eating disorders and metabolic disease. Mol Metab 2018 11;17:1-16
Schroeder M et al
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PubMed
40 Cayir A et al. Exposure to environmental toxicants reduces global N6-methyladenosine RNA methylation and alters expression of RNA methylation modulator genes. Environ Res 2019 08;175:228-234
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41 Li XC et al. The m6A demethylase ALKBH5 controls trophoblast invasion at the maternal-fetal interface by regulating the stability of <i>CYR61</i> mRNA. Theranostics 2019;9(13):3853-3865
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42 Zheng ZQ et al. Long Noncoding RNA FAM225A Promotes Nasopharyngeal Carcinoma Tumorigenesis and Metastasis by Acting as ceRNA to Sponge miR-590-3p/miR-1275 and Upregulate ITGB3. Cancer Res 2019 09;79(18):4612-4626
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43 Miao Z et al. Evolution of the RNA <i>N</i><sup>6</sup>-Methyladenosine Methylome Mediated by Genomic Duplication. Plant Physiol 2020 01;182(1):345-360
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44 Chen Y et al. WTAP facilitates progression of hepatocellular carcinoma via m6A-HuR-dependent epigenetic silencing of ETS1. Mol Cancer 2019 08;18(1):127
Chen Y et al
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PubMed
45 Wang H et al. N6-methyladenosine METTL3 promotes the breast cancer progression via targeting Bcl-2. Gene 2020 Jan;722:144076
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46 Pil転ys T et al. ALKBH overexpression in head and neck cancer: potential target for novel anticancer therapy. Sci Rep 2019 09;9(1):13249
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47 Li F et al. N<sup>6</sup>-Methyladenosine Modulates Nonsense-Mediated mRNA Decay in Human Glioblastoma. Cancer Res 2019 11;79(22):5785-5798
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PubMed
48 Xia T et al. The RNA m6A methyltransferase METTL3 promotes pancreatic cancer cell proliferation and invasion. Pathol Res Pract 2019 Nov;215(11):152666
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49 Li J et al. m6A demethylase FTO promotes hepatocellular carcinoma tumorigenesis via mediating PKM2 demethylation. Am J Transl Res 2019;11(9):6084-6092
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50 Murik O et al. Topologies of N<sup>6</sup> -adenosine methylation (m<sup>6</sup> A) in land plant mitochondria and their putative effects on organellar gene expression. Plant J 2020 03;101(6):1269-1286
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51 Ou X et al. Electrochemical competitive immunodetection of messenger&#xA0;RNA modified with N6-methyladenosine by using DNA-modified mesoporous PtCo nanospheres. Mikrochim Acta 2019 12;187(1):31
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52 Roy S et al. Phloroglucinol Treatment Induces Transgenerational Epigenetic Inherited Resistance Against <i>Vibrio</i> Infections and Thermal Stress in a Brine Shrimp (<i>Artemia franciscana</i>) Model. Front Immunol 2019;10:2745
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53 Lan T et al. KIAA1429 contributes to liver cancer progression through N6-methyladenosine-dependent post-transcriptional modification of GATA3. Mol Cancer 2019 12;18(1):186
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54 Park MH et al. Mono-(2-Ethylhexyl)phthalate Regulates Cholesterol Efflux via MicroRNAs Regulated m<sup>6</sup>A RNA Methylation. Chem Res Toxicol 2020 02;33(2):461-469
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55 Zhao TX et al. Increased m6A RNA modification is related to the inhibition of the Nrf2-mediated antioxidant response in di-(2-ethylhexyl) phthalate-induced prepubertal testicular injury. Environ Pollut 2020 Apr;259:113911
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56 Zhao T et al. N<sup>6</sup>-methyladenosine mediates arsenite-induced human keratinocyte transformation by suppressing p53 activation. Environ Pollut 2020 Apr;259:113908
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57 Su H et al. Transcriptome-wide map of m<sup>6</sup>A circRNAs identified in a rat model of hypoxia mediated pulmonary hypertension. BMC Genomics 2020 Jan;21(1):39
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58 Luo G et al. RNA m<sup>6</sup> A methylation regulates uveal melanoma cell proliferation, migration, and invasion by targeting c-Met. J Cell Physiol 2020 10;235(10):7107-7119
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59 Li G et al. Bone-derived mesenchymal stem cells alleviate compression-induced apoptosis of nucleus pulposus cells by N6 methyladenosine of autophagy. Cell Death Dis 2020 02;11(2):103
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PubMed
60 He Y et al. Increased m6A methylation level is associated with the progression of human abdominal aortic aneurysm. Ann Transl Med 2019 Dec;7(24):797
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61 Hu Y et al. Oocyte competence is maintained by m<sup>6</sup>A methyltransferase KIAA1429-mediated RNA metabolism during mouse follicular development. Cell Death Differ 2020 08;27(8):2468-2483
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62 Qiu Z et al. MYC Regulation of D2HGDH and L2HGDH Influences the Epigenome and Epitranscriptome. Cell Chem Biol 2020 05;27(5):538-550.e7
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63 Jin D et al. m<sup>6</sup>A demethylase ALKBH5 inhibits tumor growth and metastasis by reducing YTHDFs-mediated YAP expression and inhibiting miR-107/LATS2-mediated YAP activity in NSCLC. Mol. Cancer 2020 02;19(1):40
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64 Li D et al. METTL3 Modulates Osteoclast Differentiation and Function by Controlling RNA Stability and Nuclear Export. Int J Mol Sci 2020 Feb;21(5)
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65 Liu X et al. SIRT1 Regulates N<sup>6</sup> -Methyladenosine RNA Modification in Hepatocarcinogenesis by Inducing RANBP2-Dependent FTO SUMOylation. Hepatology 2020 Dec;72(6):2029-2050
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66 Diao MY et al. Hypothermia protects neurons against ischemia/reperfusion-induced pyroptosis via m6A-mediated activation of PTEN and the PI3K/Akt/GSK-3&#x3B2; signaling pathway. Brain Res Bull 2020 06;159:25-31
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67 Shen C et al. m<sup>6</sup>A-dependent glycolysis enhances colorectal cancer progression. Mol Cancer 2020 04;19(1):72
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68 Wu J et al. Resveratrol Attenuates Aflatoxin B<sub>1</sub>-Induced ROS Formation and Increase of m<sup>6</sup>A RNA Methylation. Animals (Basel) 2020 Apr;10(4)
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69 Zhang R et al. TRIM11 facilitates chemoresistance in nasopharyngeal carcinoma by activating the &#x3B2;-catenin/ABCC9 axis via p62-selective autophagic degradation of Daple. Oncogenesis 2020 May;9(5):45
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70 Wang J et al. Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis. Cell Stem Cell 2020 07;27(1):81-97.e8
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71 Wang Y et al. m<sup>6</sup>A mRNA Methylation Controls Functional Maturation in Neonatal Murine &#x3B2;-Cells. Diabetes 2020 08;69(8):1708-1722
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72 Zhang H et al. Dynamic landscape and evolution of m6A methylation in human. Nucleic Acids Res 2020 06;48(11):6251-6264
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73 Liu B et al. LncRNA SOX2OT promotes temozolomide resistance by elevating SOX2 expression via ALKBH5-mediated epigenetic regulation in glioblastoma. Cell Death Dis 2020 05;11(5):384
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74 Wu H et al. Dendritic cells with METTL3 gene knockdown exhibit immature properties and prolong allograft survival. Genes Immun 2020 05;21(3):193-202
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75 Gao Y et al. m<sup>6</sup>A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development. Immunity 2020 06;52(6):1007-1021.e8
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76 Xiang S et al. N6-methyladenosine methyltransferase METTL3 promotes colorectal cancer cell proliferation through enhancing MYC expression. Am J Transl Res 2020;12(5):1789-1806
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77 Li X et al. Alteration of N<sup>6</sup>-methyladenosine epitranscriptome profile in unilateral ureteral obstructive nephropathy. Epigenomics 2020 07;12(14):1157-1173
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78 Wilson C et al. Programmable m<sup>6</sup>A modification of cellular RNAs with a Cas13-directed methyltransferase. Nat Biotechnol 2020 12;38(12):1431-1440
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79 Huang H et al. FTO-Dependent <i>N</i><sup>6</sup>-Methyladenosine Modifications Inhibit Ovarian Cancer Stem Cell Self-Renewal by Blocking cAMP Signaling. Cancer Res 2020 08;80(16):3200-3214
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80 Zhu S et al. Dexmedetomidine Suppressed the Biological Behavior of HK-2 Cells Treated with LPS by Down-Regulating ALKBH5. Inflammation 2020 Dec;43(6):2256-2263
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81 Gao Q et al. The m<sup>6</sup>A Methylation-Regulated AFF4 Promotes Self-Renewal of Bladder Cancer Stem Cells. Stem Cells Int 2020;2020:8849218
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82 Zhang S et al. Pregnancy exposure to carbon black nanoparticles induced neurobehavioral deficits that are associated with altered m<sup>6</sup>A modification in offspring. Neurotoxicology 2020 12;81:40-50
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83 Jian D et al. METTL14 aggravates endothelial inflammation and atherosclerosis by increasing FOXO1 N6-methyladeosine modifications. Theranostics 2020;10(20):8939-8956
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84 Xu Y et al. The FTO/miR-181b-3p/ARL5B signaling pathway regulates cell migration and invasion in breast cancer. Cancer Commun (Lond) 2020 10;40(10):484-500
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85 Chen S et al. WTAP promotes osteosarcoma tumorigenesis by repressing HMBOX1 expression in an m<sup>6</sup>A-dependent manner. Cell Death Dis 2020 08;11(8):659
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86 Wei J et al. METTL3 potentiates resistance to cisplatin through m<sup>6</sup> A modification of TFAP2C in seminoma. J Cell Mol Med 2020 10;24(19):11366-11380
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87 Zhang S et al. Altered m<sup>6</sup> A modification is involved in up-regulated expression of FOXO3 in luteinized granulosa cells of non-obese polycystic ovary syndrome patients. J Cell Mol Med 2020 Oct;24(20):11874-11882
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88 Xue L et al. m<sup>6</sup> A transferase METTL3-induced lncRNA ABHD11-AS1 promotes the Warburg effect of non-small-cell lung cancer. J Cell Physiol 2021 Apr;236(4):2649-2658
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89 Guo T et al. ALKBH5 promotes colon cancer progression by decreasing methylation of the lncRNA NEAT1. Am J Transl Res 2020;12(8):4542-4549
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90 Povedano E et al. Magnetic microbeads-based amperometric immunoplatform for the rapid and sensitive detection of N6-methyladenosine to assist in metastatic cancer cells discrimination. Biosens Bioelectron 2021 Jan;171:112708
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91 Gu Y et al. Upregulation of METTL3 expression and m6A RNA methylation in placental trophoblasts in preeclampsia. Placenta 2021 Jan;103:43-49
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92 Sun D et al. Fat mass and obesity-associated protein regulates lipogenesis via m<sup>6</sup> A modification in fatty acid synthase mRNA. Cell Biol Int 2021 Feb;45(2):334-344
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93 Xiao L et al. METTL3 promotes IL-1&#x3B2;-induced degeneration of endplate chondrocytes by driving m6A-dependent maturation of miR-126-5p. J Cell Mol Med 2020 Dec;24(23):14013-14025
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94 Chang G et al. YTHDF3 Induces the Translation of m<sup>6</sup>A-Enriched Gene Transcripts to Promote Breast Cancer Brain Metastasis. Cancer Cell 2020 Dec;38(6):857-871.e7
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95 Xiao H et al. Upregulated N6-methyladenosine RNA in Peripheral Blood: Potential Diagnostic Biomarker for Breast Cancer. Cancer Res Treat 2020 Oct;
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96 Yu JT et al. DNA methylation of FTO promotes renal inflammation by enhancing m<sup>6</sup>A of PPAR-&#x3B1; in alcohol-induced kidney injury. Pharmacol Res 2021 Jan;163:105286
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97 Zhang Y et al. Long non-coding RNA IGF2-AS represses breast cancer tumorigenesis by epigenetically regulating IGF2. Exp Biol Med (Maywood) 2021 Feb;246(4):371-379
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98 Liu S et al. The mechanism of m<sup>6</sup>A methyltransferase METTL3-mediated autophagy in reversing gefitinib resistance in NSCLC cells by &#x3B2;-elemene. Cell Death Dis 2020 11;11(11):969
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99 Su Y et al. N6-methyladenosine methyltransferase plays a role in hypoxic preconditioning partially through the interaction with lncRNA H19. Acta Biochim Biophys Sin (Shanghai) 2020 Dec;52(12):1306-1315
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100 Ye J et al. YTHDF1-enhanced iron metabolism depends on TFRC m<sup>6</sup>A methylation. Theranostics 2020;10(26):12072-12089
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101 Sun HL et al. Stabilization of ERK-Phosphorylated METTL3 by USP5 Increases m<sup>6</sup>A Methylation. Mol Cell 2020 11;80(4):633-647.e7
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102 Sun X et al. Decreased expression of m<sup>6</sup>A demethylase FTO in ovarian aging. Arch Gynecol Obstet 2020 Nov;
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103 Nakagawa N et al. Novel Prognostic Implications of Methylated RNA and Demethylases in Resected HCC and Background Liver Tissue. Anticancer Res 2020 Dec;40(12):6665-6676
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104 Wu H et al. miR-338-5p inhibits cell growth and migration via inhibition of the METTL3/m6A/c-Myc pathway in lung cancer. Acta Biochim Biophys Sin (Shanghai) 2021 Mar;53(3):304-316
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105 Wu K et al. Transcriptomics and flow cytometry reveals the cytotoxicity of aflatoxin B<sub>1</sub> and aflatoxin M<sub>1</sub> in bovine mammary epithelial cells. Ecotoxicol Environ Saf 2021 Feb;209:111823
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106 Yu H et al. N<sup>6</sup>-methyladenosine (m<sup>6</sup>A) methyltransferase WTAP accelerates the Warburg effect of gastric cancer through regulating HK2 stability. Biomed Pharmacother 2021 Jan;133:111075
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107 Xu Z et al. METTL14-regulated PI3K/Akt signaling pathway via PTEN affects HDAC5-mediated epithelial-mesenchymal transition of renal tubular cells in diabetic kidney disease. Cell Death Dis 2021 Jan;12(1):32
Xu Z et al
2021/01/01
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108 He J et al. METTL3 restrains papillary thyroid cancer progression via m<sup>6</sup>A/c-Rel/IL-8-mediated neutrophil infiltration. Mol Ther 2021 Jan;
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109 Sun L et al. Triclosan-induced abnormal expression of miR-30b regulates fto-mediated m<sup>6</sup>A methylation level to cause lipid metabolism disorder in zebrafish. Sci Total Environ 2021 May;770:145285
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110 Izquierdo V et al. Resveratrol Supplementation Attenuates Cognitive and Molecular Alterations under Maternal High-Fat Diet Intake: Epigenetic Inheritance over Generations. Int J Mol Sci 2021 Feb;22(3)
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111 Shen W et al. FTO overexpression inhibits apoptosis of hypoxia/reoxygenation-treated myocardial cells by regulating m6A modification of Mhrt. Mol Cell Biochem 2021 Feb;
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112 Xu S. et. al.The Role of RNA m6A Methylation in the Regulation of Postnatal Hypoxia-induced Pulmonary Hypertension., Respiratory Research BMC.,

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