抗VEGF抗体 | Anti-VEGF antibody

• 特長
• 価格
• DATA IMAGES
• 製品情報
• APPLICATION
• PROPERTIES
• TARGET

特長

• 高品質の抗体です。
• 幅広い研究分野に関連する抗体を取り揃えています。
• 使用されたアプリケーションや動物種などの情報が充実しています。
• 多数の論文で使用実績がある信頼性の高い抗体です。

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価格

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DATA IMAGES

	IHC-P analysis of human breast invasive ductal carcinoma using VEGF antibody. An HRP-labeled polymer detection system was used with a DAB chromogen. This antibody was also tested in an HRP-biotin labeling detection system. Heat induced antigen retrieval with a pH 6.0 Sodium Citrate buffer is recommended.
	IHC-P analysis of human breast invasive ductal carcinoma using VEGF antibody. An HRP-labeled polymer detection system was used with a DAB chromogen. This antibody was also tested in an HRP-biotin labeling detection system. Heat induced antigen retrieval with a pH 6.0 Sodium Citrate buffer is recommended.

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製品情報

Host	Goat
Clonality	Polyclonal
Application	WB, IHC-P, ELISA, Neutralizing/Blocking
Reactivity	Human

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APPLICATION

Application Note

We recommend the following starting dilutions: For IHC-P: Use at a concentration of 5.0 μg/ml-15.0 μg/ml. Heat induced antigen retrieval with a pH 6.0 sodium citrate buffer is recommended. For WB: Use at a concentration of 0.1 - 0.2 μg/ml. For ELISA: Use at a concentration of 0.5 - 2.0 μg/ml. For Neutralization: one-half maximal inhibition [ND50] of the biological activity of hVEGF (10 ng/ml), a concentration of 0.05 - 0.1 μg/ml of this antibody is required. Optimal dilutions should be determined experimentally by the end user.

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PROPERTIES

Form	Liquid
Buffer	PBS, pH 7.2
Storage	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration	Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species	Human
Immunogen	The immunogen corresponding to a region within amino acids 27 and 191 of human VEGF165.
Purification	Affinity Purified
Conjugation	Unconjugated
Note	For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

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TARGET

Synonyms

VPF Antibody , VEGFA Antibody , MVCD1 Antibody , vascular endothelial growth factor A Antibody

Background

This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms. [provided by RefSeq, Jul 2008]

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