DPNI-caged-GABA (1-(4-Aminobutanoyl)-4-[1,3-bis(dihydroxyphosphoryloxy)propan-2-yloxy]-7-nitroindoline) | 927866-58-8

name

dpni-caged-gaba

chemical name

1-(4-aminobutanoyl)-4-[1,3-bis(dihydroxyphosphoryloxy)propan-2-yloxy]-7-nitroindoline

activity

nitroindoline-caged gaba (cat.no. 0344) with similar photochemical properties to mni-glutamate (cat. no. 1490); for example, the same quantum yield (0.085). highly water soluble; exhibits fast photorelease that is efficient at near-uv and 405 nm wavelengths.

MW

499.3

Formula:

c15h23n3o12p2

Solubility:

soluble to 10 mm in water with gentle warming

Purity:

>98 %

Storage:

store at -20°c

CAS No:

927866-58-8

Wieboldt et al (1994) Synthesis and photochemistry of photolabile derivatives of gamma-aminobutyric acid for chemical kinetic investigations of the gamma-aminobutyric acid receptor in the millisecond time region. Biochemistry 33 1526. PMID: 8312272.

Trigo et al (2009) Laser photolysis of DPNI-GABA, a tool for investigating the properties and distribution of GABA receptors and for silencing neurons in situ. J.Neurosci.Meths. 181 159.

Trigo (2010) Presynaptic miniature GABAergic currents in developing interneurons. Neuron 66 235. PMID: 20435000.