IGF-I 組換え体(リコンビナント)タンパク質 | Recombinant Mouse IGF-I
掲載日情報：2015/01/26 現在Webページ番号：113201
R&D Systems社製の高品質なIGF-Iの組換え体タンパク質(Recombinant Mouse IGF-I)です。
※本製品は研究用です。研究用以外には使用できません。
[在庫・価格 ：2025年07月20日 00時00分現在]
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[在庫・価格 ：2025年07月20日 00時00分現在]
IGF-I/IGF-1, Mouse, Recombinant, Carrier-free
文献数： 43
- 商品コード：791-MG-050
- メーカー：RSD
- 包装：50μg
- 価格：¥36,000
- 在庫：1個
- 納期：10日程度 ※※ 表示されている納期は弊社に在庫がなく、取り寄せた場合の目安納期となります。
- 法規制等：
| 説明文 | 産生：E. coli，純度：>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by CoomassieR Blue Staining.，由来動物：Mouse，M.W.：7.6 kDa，Genbank：3479，エンドトキシンレベル：<0.10 EU per 1 μg of the protein by the LAL method. 別名：IBP1 Genbank No： 3479 Protein Accession No： Q8CAR0 |
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| 保存条件 | -20℃ | 法規備考 | |
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バルク注文に関して
※バルク包装品も承ります。お気軽にお問合せ下さい。
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CF(Carrier-Free)とは？
R&D Systems社組換え体タンパク質製品では通常ウシ血清アルブミン(BSA)をキャリアタンパク質として加えています。キャリアタンパク質を加えることで組換え体タンパク質の安定性が高まり、使用期限が長くなります。また、より濃度の低い溶液での保管も可能となります。CF製品はBSAが含まれない製品となります。一般的に細胞培養や、ELISAのスタンダードにはBSA含有製品を推奨しています。CF製品はBSAが影響してしまうアプリケーションに推奨されます。
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Product Details
- Source
- E. coli-derived, Gly33-Ala102
- Accession
- Q8CAR0
- Purity
- >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
- Predicted Molecular Mass
- 7.6 kDa
- Activity
- Measured in a serum-free cell proliferation assay using MCF‑7 human breast cancer cells. Karey, K.P. et al. (1988) Cancer Research 48
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Additional Information
- Molecule Information
- IGF-I
- Aliases
- IGF1; IGF-1; Somatomedin A; Somatomedin C
- Entrez Gene IDs
- 3479 (Human); 16000 (Mouse); 24482 (Rat)
- Background
- IGF Ligands
- Insulin-like growth factor (IGF)-I (also known as somatomedin C and somatomedin A) and IGF-II (multiplication stimulating activity or MSA) belong to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGF-I and IGF-II share approximately 70% sequence identity. Both IGF-I and IGF-II are expressed in many tissues and cell types and may have autocrine, paracrine and endocrine functions. Mature IGF-I and IGF-II are highly conservedbetween the human, bovine and porcine proteins (100% identity), and exhibit cross-species activity.The IGFL (insulin-like growth factor-like) family includes four small (~11 kDa), probably secreted family members in humans and one in mouse. This family shares A and B chain cysteine motifs with the IGF superfamily, and has an additional cysteine motif within an uncleaved region corresponding to the C peptide of the IGF family.
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Citations
Citations of cell biology reagents in peer reviewed literature can be used as a direct measure of product quality. They can also provide crucial insightinto their use under specialized or unique experimental conditions. Because of the importance published citations have to researchers, R&D Systems personnelmanually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but alsoprovides information about sample types, species, and experimental conditions.
Myostatin stimulates, not inihibits, C2C12 myoblast proliferation.
Hoversten K, Jackson M, Rodgers B, Thompson T, Walker R, Wiedeback B
Endocrinology 2014 155:670-5
Species: Mouse
Protein Application: Bioassay
The restorative effects of adipose-derived mesenchymal stem cells on damaged ovarian function.
Aida , Takuya, Aono , Fumihito, Aoyama , Naoki, Ezoe , Kenji, Kato , Keiich, Kato , Osamu, Kuroda , Tomoko, Murata , Nana, Nakama , Ken, Sano , Chiaki, Takehara , Yuji, Yabuuchi , Akiko, Yamadera , Rie
Lab Invest 2013 93:181-93
Species: Mouse
Protein Application: Bioassay
Recombinant insulin-like growth factor-1 activates satellite cells in the mouse urethral rhabdosphincter.
Howard P, Macarak E, Wei W
BMC Urol 2013 13:62
Species: Mouse
Protein Application: In Vivo
Exercise induces hippocampal BDNF through a PGC-1alpha/FNDC5 pathway.
Greenberg M, Laznik-Bogoslavski D, Lin J, Ma D, Salogiannnis J, Spiegelman B, White J, Wrann C, Wu J
Cell Metab 2013 18:649-59
Species: Mouse
Protein Application: Cell Culture Substrate
Age-Dependent Neuroimmune Modulation of IGF-1R in the Traumatic Mice.
Cao X, Wu G, Zhao H, Zhao X
Immun Ageing 2012 9:12
Species: Mouse
Protein Application: Bioassay
A critical role for IGF-II in memory consolidation and enhancement.
Alberini CM, Bambah-Mukku D, Blitzer RD, Chen DY, Garcia-Osta A, Pollonini G, Saunier-Rebori B, Stern SA
Nature 2011 469:491-7
Species: Rat
Protein Application: In Vivo
Insulin-like Growth Factor 1-mediated Hyperthermia Involves Anterior Hypothalamic Insulin Receptors.
Osborn O, Sanchez-Alavez M, Tabarean IV
J. Biol. Chem. 2011 286:14983-90
Species: Mouse
Protein Application: In Vivo
IGFBP-3 is a metastasis suppression gene in prostate cancer.
Galet C, Gao Q, Mehta HH
Cancer Res. 2011 71:5154-63
Species: N/A
Protein Application: ELISA Standard
Evidence of a role for insulin-like growth factor binding protein (IGFBP)-3 in metabolic regulation.
Hwang D, Mehta HH, Yamada PM
Endocrinology 2010 151:5741-50
Species: N/A
Protein Application: ELISA Standard
The chaperone activity of GRP94 toward insulin-like growth factor II is necessary for the stress response to serum deprivation.
Ahmed NT, Argon Y, Ostrovsky O
Mol. Biol. Cell 2009 20:1855-64
Species: Mouse
Protein Application: Bioassay
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