IL-2 組換え体(リコンビナント)タンパク質 | Recombinant Human IL-2

R&D Systems社製の高品質なIL-2の組換え体タンパク質(Recombinant Human IL-2)です。
※本製品は研究用です。研究用以外には使用できません。

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R&D Systems社組換え体タンパク質製品では通常ウシ血清アルブミン(BSA)をキャリアタンパク質として加えています。キャリアタンパク質を加えることで組換え体タンパク質の安定性が高まり、使用期限が長くなります。また、より濃度の低い溶液での保管も可能となります。CF製品はBSAが含まれない製品となります。一般的に細胞培養や、ELISAのスタンダードにはBSA含有製品を推奨しています。CF製品はBSAが影響してしまうアプリケーションに推奨されます。

Citations of cell biology reagents in peer reviewed literature can be used as a direct measure of product quality. They can also provide crucial insightinto their use under specialized or unique experimental conditions. Because of the importance published citations have to researchers, R&D Systems personnelmanually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but alsoprovides information about sample types, species, and experimental conditions.

Retagging identifies dendritic cell-specific intercellular adhesion molecule-3 (ICAM3)-grabbing non-integrin (DC-SIGN) protein as a novel receptor for a major allergen from house dust mite.
Emara M, Mahdavi J, Royer PJ
J. Biol. Chem. 2012 287:5756-63
Species: Human
Protein Application: Bioassay


Identification of myeloid derived suppressor cells in dogs with naturally occurring cancer.
Goulart MR, Ohlfest JR, Pluhar GE
PLoS ONE 2012 7:e33274
Species: Canine
Protein Application: Bioassay


Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'.
Bates DL, Bowman GR, Boyman O, Fathman CG, Garcia KC, Krieg C, Levin AM, Lin JT, Moraga I, Novick P, Pande VS, Raeber ME, Ring AM, Su L
Nature 2012 484:529-33
Species: Mouse
Protein Application: In Vivo


Antigen-independent induction of Tim-3 expression on human T cells by the common gamma-chain cytokines IL-2, IL-7, IL-15, and IL-21 is associated with proliferation and is dependent on the phosphoinositide 3-kinase pathway.
Aidarus N, Benko E, Clayton K, Jones RB, Kovacs C, Lo C, Mujib S, Ostrowski MA, Sakhdari A
J. Immunol. 2012 188:3745-56
Species: Human
Protein Application: Bioassay


Role of Smad proteins in resistance to BMP-induced growth inhibition in B-cell lymphoma.
Alizadeh A, Bakkebo M, Bredahl M, Forfang L, Hilden V, Huse K, Liestol K, Myklebust J, Oksvold M, Smeland E, Walchli S
PLoS ONE 2012 7:e46117
Species: Human
Protein Application: Bioassay


Tumor Microenvironment Macrophage Inhibitory Factor Directs the Accumulation of Interleukin-17-producing Tumor-infiltrating Lymphocytes and Predicts Favorable Survival in Nasopharyngeal Carcinoma Patients.
Chen Q, Du Z, He J, Huang Z, Li J, Liu Z, Mo H, Qian C, Xiong G, Zeng Y, Zhang L, Zheng L
J Biol Chem 2012 287:35484-95

Indoleamine 2,3-dioxygenase 1 (IDO1) activity correlates with immune system abnormalities in multiple myeloma.
Bonanno G, Ciciarello M, De Cristofaro R, De Rosa L, Folgiero V, Gambella M, Locatelli F, Majolino I, Mariotti A, Natale D, Novarese L, Palumbo A, Procoli A, Rocci A, Rutella S, Scambia G
J Transl Med 2012 10:247
Species: Human
Protein Application: Bioassay


The IL23R R381Q Gene Variant Protects against Immune-Mediated Diseases by Impairing IL-23-Induced Th17 Effector Response in Humans.
Di Cesare A, Di Meglio P, Laggner U
PLoS ONE 2011 6:e17160
Species: Human
Protein Application: Bioassay


Th17 cells expressing KIR3DL2+ and responsive to HLA-B27 homodimers are increased in ankylosing spondylitis.
Bowness P, Ridley A, Shaw J
J. Immunol. 2011 186:2672
Species: Human
Protein Application: Bioassay


HDAC11 plays an essential role in regulating OX40 ligand expression in Hodgkin lymphoma.
Buglio D, Khaskhely NM, Liu YJ, Martinez-Valdez H, Voo KS, Younes A
Blood 2011 117:2910-7
Species: Human
Protein Application: Bioassay