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在庫・価格 : 2024年05月30日 16時04分 現在

商品名 商品コード メーカー 包装 価格 在庫 リスト
Z-Tyr-Val-Ala-Asp(OMe)-FMK <Z-YVAD-FMK> <Caspase-4 Inhibitor>
データシート※最新のデータシートでない場合があります
FMK005 RSDアールアンドディー システムス
R&D Systems, Inc.
1 mg ¥56,000
(未発注)
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在庫・価格 : 2024年05月30日 16時04分 現在

Z-Tyr-Val-Ala-Asp(OMe)-FMK <Z-YVAD-FMK> <Caspase-4 Inhibitor>

  • 商品コード:FMK005
  • メーカー:RSD
  • 包装:1mg
  • 価格: ¥56,000
  • 在庫:無(未発注)
使用文献
No. 文献情報 備考 参照
1 Edgeworth JD et al. Cytotoxicity and interleukin-1beta processing following Shigella flexneri infection of human monocyte-derived dendritic cells. Eur. J. Immunol. 2002 May;32(5):1464-71
Edgeworth JD et al
2002/01/01
Sample Type: Whole Cells PubMed
2 Vergote D et al. (-)-Epigallocatechin (EGC) of green tea induces apoptosis of human breast cancer cells but not of their normal counterparts. Breast Cancer Res. Treat. 2002 Dec;76(3):195-201
Vergote D et al
2002/01/01
Sample Type: Whole Cells PubMed
3 Attali G et al. Increased sensitivity of early apoptotic cells to complement-mediated lysis. Eur. J. Immunol. 2004 Nov;34(11):3236-45
Attali G et al
2004/01/01
Sample Type: Whole Cells PubMed
4 Wu MF et al. CLEC5A is critical for dengue virus-induced inflammasome activation in human macrophages. Blood 2013 Jan;121(1):95-106
Wu MF et al
2013/01/01
Application: Inhibitor, Sample Type: whole cells PubMed
5 McCloy RA et al. Role of endoplasmic reticulum stress induction by the plant toxin, persin, in overcoming resistance to the apoptotic effects of tamoxifen in human breast cancer cells. Br. J. Cancer 2013 Dec;109(12):3034-41
McCloy RA et al
2013/01/01
Application: cell culture, Sample Type: whole cells PubMed
6 Teigler JE et al. Late endosomal trafficking of alternative serotype adenovirus vaccine vectors augments antiviral innate immunity. J. Virol. 2014 Sep;88(18):10354-63
Teigler JE et al
2014/01/01
Sample Type: Whole Cells PubMed
7 Li Q et al. The cleavage pattern of TDP-43 determines its rate of clearance and cytotoxicity. Nat Commun 2015;6:6183
Li Q et al
2015/01/01
Sample Type: Whole Cells PubMed
8 Yakut E et al. Extracorporeal photopheresis promotes IL-1&#x3B2; production. J. Immunol. 2015 Mar;194(6):2569-77
Yakut E et al
2015/01/01
Sample Type: Whole Cells PubMed
9 Zwack EE et al. Inflammasome activation in response to the Yersinia type III secretion system requires hyperinjection of translocon proteins YopB and YopD. MBio 2015;6(1):e02095-14
Zwack EE et al
2015/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
10 Whidbey C et al. A streptococcal lipid toxin induces membrane permeabilization and pyroptosis leading to fetal injury. EMBO Mol Med 2015 Apr;7(4):488-505
Whidbey C et al
2015/01/01
Sample Type: Cell culture PubMed
11 Roulstone V et al. BRAF- and MEK-Targeted Small Molecule Inhibitors Exert Enhanced Antimelanoma Effects in Combination With Oncolytic Reovirus Through ER Stress. Mol. Ther. 2015 May;23(5):931-42
Roulstone V et al
2015/01/01
Sample Type: Whole Cells PubMed
12 Callaway JB et al. Spleen Tyrosine Kinase (Syk) Mediates IL-1&#x3B2; Induction by Primary Human Monocytes during Antibody-enhanced Dengue Virus Infection. J. Biol. Chem. 2015 Jul;290(28):17306-20
Callaway JB et al
2015/01/01
Sample Type: Whole Cells PubMed
13 Callaway JB et al. Source and Purity of Dengue-Viral Preparations Impact Requirement for Enhancing Antibody to Induce Elevated IL-1&#x3B2; Secretion: A Primary Human Monocyte Model. PLoS ONE 2015;10(8):e0136708
Callaway JB et al
2015/01/01
Sample Type: Whole Cells PubMed
14 Gonz叩lez-Juarbe N et al. Pore-Forming Toxins Induce Macrophage Necroptosis during Acute Bacterial Pneumonia. PLoS Pathog. 2015 Dec;11(12):e1005337
Gonz叩lez-Juarbe N et al
2015/01/01
Sample Type: Whole Cells PubMed
15 Thurston TL et al. Growth inhibition of cytosolic Salmonella by caspase-1 and caspase-11 precedes host cell death. Nat Commun 2016 Nov;7:13292
Thurston TL et al
2016/01/01
Application: Bioassay PubMed
16 Naschberger E et al. Processing and secretion of guanylate binding protein-1 depend on inflammatory caspase activity. J. Cell. Mol. Med. 2017 Sep;21(9):1954-1966
Naschberger E et al
2017/01/01
Application: Bioassay, Sample Type: Whole Cells PubMed
17 Nishijima N et al. Human Scavenger Receptor A1-Mediated Inflammatory Response to Silica Particle Exposure Is Size Specific. Front Immunol 2017;8:379
Nishijima N et al
2017/01/01
Species: Human, Applications: Bioassay PubMed
18 Baek JH et al. PLOD3 suppression exerts an anti-tumor effect on human lung cancer cells by modulating the PKC-delta signaling pathway. Cell Death Dis 2019 Feb;10(3):156
Baek JH et al
2019/01/01
PubMed
19 Tang AC et al. Combination therapy with proteasome inhibitors and TLR agonists enhances tumour cell death and IL-1&#x3B2; production. Cell Death Dis 2018 Feb;9(2):162
Tang AC et al
2018/01/01
PubMed
20 LaRock CN et al. IL-1&#x3B2; is an innate immune sensor of microbial proteolysis. Sci Immunol 2016 Aug;1(2)
LaRock CN et al
2016/01/01
PubMed
21 Scott LM et al. Production and regulation of interleukin-1 family cytokines at the materno-fetal interface. Cytokine 2017 Nov;99:194-202
Scott LM et al
2017/01/01
PubMed
22 Freeman L et al. NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes. J. Exp. Med. 2017 05;214(5):1351-1370
Freeman L et al
2017/01/01
PubMed
23 Liu J et al. Corticosterone Preexposure Increases NF-&#x3BA;B Translocation and Sensitizes IL-1&#x3B2; Responses in BV2 Microglia-Like Cells. Front Immunol 2018;9:3
Liu J et al
2018/01/01
PubMed
24 Sun J et al. The Pseudomonas aeruginosa protease LasB directly activates IL-1&#x3B2;. EBioMedicine 2020 Oct;60:102984
Sun J et al
2020/01/01
Species: Mouse, Applications: Bioassay PubMed
  • No.: 1
  • 文献情報:
    Edgeworth JD et al. Cytotoxicity and interleukin-1beta processing following Shigella flexneri infection of human monocyte-derived dendritic cells. Eur. J. Immunol. 2002 May;32(5):1464-71
    Edgeworth JD et al
    2002/01/01
  • 備考:
    Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 2
  • 文献情報:
    Vergote D et al. (-)-Epigallocatechin (EGC) of green tea induces apoptosis of human breast cancer cells but not of their normal counterparts. Breast Cancer Res. Treat. 2002 Dec;76(3):195-201
    Vergote D et al
    2002/01/01
  • 備考:
    Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 3
  • 文献情報:
    Attali G et al. Increased sensitivity of early apoptotic cells to complement-mediated lysis. Eur. J. Immunol. 2004 Nov;34(11):3236-45
    Attali G et al
    2004/01/01
  • 備考:
    Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 4
  • 文献情報:
    Wu MF et al. CLEC5A is critical for dengue virus-induced inflammasome activation in human macrophages. Blood 2013 Jan;121(1):95-106
    Wu MF et al
    2013/01/01
  • 備考:
    Application: Inhibitor, Sample Type: whole cells
  • 参照:
    PubMed
  • No.: 5
  • 文献情報:
    McCloy RA et al. Role of endoplasmic reticulum stress induction by the plant toxin, persin, in overcoming resistance to the apoptotic effects of tamoxifen in human breast cancer cells. Br. J. Cancer 2013 Dec;109(12):3034-41
    McCloy RA et al
    2013/01/01
  • 備考:
    Application: cell culture, Sample Type: whole cells
  • 参照:
    PubMed
  • No.: 6
  • 文献情報:
    Teigler JE et al. Late endosomal trafficking of alternative serotype adenovirus vaccine vectors augments antiviral innate immunity. J. Virol. 2014 Sep;88(18):10354-63
    Teigler JE et al
    2014/01/01
  • 備考:
    Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 7
  • 文献情報:
    Li Q et al. The cleavage pattern of TDP-43 determines its rate of clearance and cytotoxicity. Nat Commun 2015;6:6183
    Li Q et al
    2015/01/01
  • 備考:
    Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 8
  • 文献情報:
    Yakut E et al. Extracorporeal photopheresis promotes IL-1&#x3B2; production. J. Immunol. 2015 Mar;194(6):2569-77
    Yakut E et al
    2015/01/01
  • 備考:
    Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 9
  • 文献情報:
    Zwack EE et al. Inflammasome activation in response to the Yersinia type III secretion system requires hyperinjection of translocon proteins YopB and YopD. MBio 2015;6(1):e02095-14
    Zwack EE et al
    2015/01/01
  • 備考:
    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 10
  • 文献情報:
    Whidbey C et al. A streptococcal lipid toxin induces membrane permeabilization and pyroptosis leading to fetal injury. EMBO Mol Med 2015 Apr;7(4):488-505
    Whidbey C et al
    2015/01/01
  • 備考:
    Sample Type: Cell culture
  • 参照:
    PubMed
  • No.: 11
  • 文献情報:
    Roulstone V et al. BRAF- and MEK-Targeted Small Molecule Inhibitors Exert Enhanced Antimelanoma Effects in Combination With Oncolytic Reovirus Through ER Stress. Mol. Ther. 2015 May;23(5):931-42
    Roulstone V et al
    2015/01/01
  • 備考:
    Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 12
  • 文献情報:
    Callaway JB et al. Spleen Tyrosine Kinase (Syk) Mediates IL-1&#x3B2; Induction by Primary Human Monocytes during Antibody-enhanced Dengue Virus Infection. J. Biol. Chem. 2015 Jul;290(28):17306-20
    Callaway JB et al
    2015/01/01
  • 備考:
    Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 13
  • 文献情報:
    Callaway JB et al. Source and Purity of Dengue-Viral Preparations Impact Requirement for Enhancing Antibody to Induce Elevated IL-1&#x3B2; Secretion: A Primary Human Monocyte Model. PLoS ONE 2015;10(8):e0136708
    Callaway JB et al
    2015/01/01
  • 備考:
    Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 14
  • 文献情報:
    Gonz叩lez-Juarbe N et al. Pore-Forming Toxins Induce Macrophage Necroptosis during Acute Bacterial Pneumonia. PLoS Pathog. 2015 Dec;11(12):e1005337
    Gonz叩lez-Juarbe N et al
    2015/01/01
  • 備考:
    Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 15
  • 文献情報:
    Thurston TL et al. Growth inhibition of cytosolic Salmonella by caspase-1 and caspase-11 precedes host cell death. Nat Commun 2016 Nov;7:13292
    Thurston TL et al
    2016/01/01
  • 備考:
    Application: Bioassay
  • 参照:
    PubMed
  • No.: 16
  • 文献情報:
    Naschberger E et al. Processing and secretion of guanylate binding protein-1 depend on inflammatory caspase activity. J. Cell. Mol. Med. 2017 Sep;21(9):1954-1966
    Naschberger E et al
    2017/01/01
  • 備考:
    Application: Bioassay, Sample Type: Whole Cells
  • 参照:
    PubMed
  • No.: 17
  • 文献情報:
    Nishijima N et al. Human Scavenger Receptor A1-Mediated Inflammatory Response to Silica Particle Exposure Is Size Specific. Front Immunol 2017;8:379
    Nishijima N et al
    2017/01/01
  • 備考:
    Species: Human, Applications: Bioassay
  • 参照:
    PubMed
  • No.: 18
  • 文献情報:
    Baek JH et al. PLOD3 suppression exerts an anti-tumor effect on human lung cancer cells by modulating the PKC-delta signaling pathway. Cell Death Dis 2019 Feb;10(3):156
    Baek JH et al
    2019/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 19
  • 文献情報:
    Tang AC et al. Combination therapy with proteasome inhibitors and TLR agonists enhances tumour cell death and IL-1&#x3B2; production. Cell Death Dis 2018 Feb;9(2):162
    Tang AC et al
    2018/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 20
  • 文献情報:
    LaRock CN et al. IL-1&#x3B2; is an innate immune sensor of microbial proteolysis. Sci Immunol 2016 Aug;1(2)
    LaRock CN et al
    2016/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 21
  • 文献情報:
    Scott LM et al. Production and regulation of interleukin-1 family cytokines at the materno-fetal interface. Cytokine 2017 Nov;99:194-202
    Scott LM et al
    2017/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 22
  • 文献情報:
    Freeman L et al. NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes. J. Exp. Med. 2017 05;214(5):1351-1370
    Freeman L et al
    2017/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 23
  • 文献情報:
    Liu J et al. Corticosterone Preexposure Increases NF-&#x3BA;B Translocation and Sensitizes IL-1&#x3B2; Responses in BV2 Microglia-Like Cells. Front Immunol 2018;9:3
    Liu J et al
    2018/01/01
  • 備考:
  • 参照:
    PubMed
  • No.: 24
  • 文献情報:
    Sun J et al. The Pseudomonas aeruginosa protease LasB directly activates IL-1&#x3B2;. EBioMedicine 2020 Oct;60:102984
    Sun J et al
    2020/01/01
  • 備考:
    Species: Mouse, Applications: Bioassay
  • 参照:
    PubMed