Anti-Adipophilin, N-terminal, Guinea Pig-Poly <Anti-ADRP>

データシート

• 商品コード：GP40
• メーカー：POG
• 包装：100μl
• 価格： ¥89,000
• 在庫：無(未発注)

マイリストに追加 マイリストに追加済

• No.： 1
• 文献情報：
  Kaushik S et al. Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis. Nat. Cell Biol. 2015 Jun;17(6):759-70
  Kaushik S et al
  2015/01/01
  
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• No.： 2
• 文献情報：
  Kozusko K et al. Clinical and molecular characterization of a novel PLIN1 frameshift mutation identified in patients with familial partial lipodystrophy. Diabetes 2015 Jan;64(1):299-310
  Kozusko K et al
  2015/01/01
  
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• No.： 3
• 文献情報：
  Camus G et al. The hepatitis C virus core protein inhibits adipose triglyceride lipase (ATGL)-mediated lipid mobilization and enhances the ATGL interaction with comparative gene identification 58 (CGI-58) and lipid droplets. J. Biol. Chem. 2014 Dec;289(52
  Camus G et al
  2014/01/01
  
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• No.： 4
• 文献情報：
  Kuramoto K et al. Deficiency of a lipid droplet protein, perilipin 5, suppresses myocardial lipid accumulation, thereby preventing type 1 diabetes-induced heart malfunction. Mol. Cell. Biol. 2014 Jul;34(14):2721-31
  Kuramoto K et al
  2014/01/01
  
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• No.： 5
• 文献情報：
  Valapala M et al. Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/&#x3B2;A3/A1-crystallin via V-ATPase-MTORC1 signaling. Autophagy 2014 Mar;10(3):480-96
  Valapala M et al
  2014/01/01
  
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• No.： 6
• 文献情報：
  Dahlhoff M et al. PLIN2, the major perilipin regulated during sebocyte differentiation, controls sebaceous lipid accumulation in vitro and sebaceous gland size in vivo. Biochim. Biophys. Acta 2013 Oct;1830(10):4642-9
  Dahlhoff M et al
  2013/01/01
  
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• No.： 7
• 文献情報：
  Pauloin A et al. Prolactin and epidermal growth factor stimulate adipophilin synthesis in HC11 mouse mammary epithelial cells via the PI3-kinase/Akt/mTOR pathway. Biochim. Biophys. Acta 2012 May;1823(5):987-96
  Pauloin A et al
  2012/01/01
  
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• No.： 8
• 文献情報：
  Bosma M et al. The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria. Histochem. Cell Biol. 2012 Feb;137(2):205-16
  Bosma M et al
  2012/01/01
  
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  Application: WB
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• No.： 9
• 文献情報：
  MacPherson RE et al. Subcellular localization of skeletal muscle lipid droplets and PLIN family proteins OXPAT and ADRP at rest and following contraction in rat soleus muscle. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2012 Jan;302(1):R29-36
  MacPherson RE et al
  2012/01/01
  
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• No.： 10
• 文献情報：
  Lenz LS et al. Adipocyte-specific inactivation of Acyl-CoA synthetase fatty acid transport protein 4 (Fatp4) in mice causes adipose hypertrophy and alterations in metabolism of complex lipids under high fat diet. J. Biol. Chem. 2011 Oct;286(41):35578-87
  Lenz LS et al
  2011/01/01
  
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• No.： 11
• 文献情報：
  Timmers S et al. Paradoxical increase in TAG and DAG content parallel the insulin sensitizing effect of unilateral DGAT1 overexpression in rat skeletal muscle. PLoS ONE 2011;6(1):e14503
  Timmers S et al
  2011/01/01
  
• 備考：
  Application: WB
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• No.： 12
• 文献情報：
  Chang BH et al. Absence of adipose differentiation related protein upregulates hepatic VLDL secretion, relieves hepatosteatosis, and improves whole body insulin resistance in leptin-deficient mice. J. Lipid Res. 2010 Aug;51(8):2132-42
  Chang BH et al
  2010/01/01
  
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• No.： 13
• 文献情報：
  Akhtar N et al. Molecular dissection of integrin signalling proteins in the control of mammary epithelial development and differentiation. Development 2009 Mar;136(6):1019-27
  Akhtar N et al
  2009/01/01
  
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• No.： 14
• 文献情報：
  Kaushik S et al. AMPK-dependent phosphorylation of lipid droplet protein PLIN2 triggers its degradation by CMA. Autophagy 2016;12(2):432-8
  Kaushik S et al
  2016/01/01
  
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• No.： 15
• 文献情報：
  Gallardo-Montejano VI et al. Nuclear Perilipin 5 integrates lipid droplet lipolysis with PGC-1&#x3B1;/SIRT1-dependent transcriptional regulation of mitochondrial function. Nat Commun 2016 Aug;7:12723
  Gallardo-Montejano VI et al
  2016/01/01
  
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• No.： 16
• 文献情報：
  Fern叩ndez-Rojo MA et al. Caveolin-1 is necessary for hepatic oxidative lipid metabolism: evidence for crosstalk between caveolin-1 and bile acid signaling. Cell Rep 2013 Jul;4(2):238-47
  Fern叩ndez-Rojo MA et al
  2013/01/01
  
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• No.： 17
• 文献情報：
  Straub BK et al. Differential pattern of lipid droplet-associated proteins and de novo perilipin expression in hepatocyte steatogenesis. Hepatology 2008 Jun;47(6):1936-46
  Straub BK et al
  2008/01/01
  
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• No.： 18
• 文献情報：
  Ohsaki Y et al. Fixation and permeabilization protocol is critical for the immunolabeling of lipid droplet proteins. Histochem. Cell Biol. 2005 Nov;124(5):445-52
  Ohsaki Y et al
  2005/01/01
  
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• No.： 19
• 文献情報：
  Fukumoto S et al. Deformation of lipid droplets in fixed samples. Histochem. Cell Biol. 2002 Nov;118(5):423-8
  Fukumoto S et al
  2002/01/01
  
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• No.： 20
• 文献情報：
  Heid HW et al. Adipophilin is a specific marker of lipid accumulation in diverse cell types and diseases. Cell Tissue Res. 1998 Nov;294(2):309-21
  Heid HW et al
  1998/01/01
  
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• No.： 21
• 文献情報：
  Heid HW et al. Adipocyte differentiation-related protein is secreted into milk as a constituent of milk lipid globule membrane. Biochem. J. 1996 Dec;320 ( Pt 3):1025-30
  Heid HW et al
  1996/01/01
  
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• No.： 22
• 文献情報：
  Yamaguchi T et al. Analysis of interaction partners for perilipin and ADRP on lipid droplets. Mol. Cell. Biochem. 2006 Mar;284(1-2):167-73
  Yamaguchi T et al
  2006/01/01
  
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• No.： 23
• 文献情報：
  Furukawa S et al. Databases for technical aspects of immunohistochemistry. J Toxicol Pathol 2017 Jan;30(1):79-107
  Furukawa S et al
  2017/01/01
  
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• No.： 24
• 文献情報：
  Straub BK et al. Adipophilin/perilipin-2 as a lipid droplet-specific marker for metabolically active cells and diseases associated with metabolic dysregulation. Histopathology 2013 Mar;62(4):617-31
  Straub BK et al
  2013/01/01
  
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• No.： 25
• 文献情報：
  Losier, T. et al. AMPK Promotes Xenophagy through Priming of Autophagic Kinases upon Detection of Bacterial Outer Membrane Vesicles. Cell.Rep. 26, 2150-2165.e5 (2019)
  
  
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• No.： 26
• 文献情報：
  Daemen, S. et al. Distinct lipid droplet characteristics and distribution unmask the apparent contradiction of the athlete&quot;s paradox. Mol.Metab. 17, 71-81 (2018).
  
  
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• No.： 27
• 文献情報：
  Lenz, L.-S. et al. Adipocyte-specific Inactivation of Acyl-CoA Synthetase Fatty Acid Transport Protein 4 (Fatp4) in Mice Causes Adipose Hypertrophy and Alterations in Metabolism of Complex Lipids under High Fat Diet. J. Biol. Chem. 286, 35578-35587 (2011
  
  
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• 参照：
  

• No.： 28
• 文献情報：
  Kaushik, S. & Cuervo, A. M. AMPK-dependent phosphorylation of lipid droplet protein PLIN2 triggers its degradation by CMA. Autophagy 12, 432-438 (2016).
  
  
• 備考：
  
• 参照：
  

• No.： 29
• 文献情報：
  Gemmink, A. et al. Lipid droplet dynamics and insulin sensitivity upon a 5-day high-fat diet in Caucasians and South Asians. Sci. Rep. 7, 1–9 (2017).
  
  
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• No.： 30
• 文献情報：
  Yang, Y. et al. Angiotensin II induces cholesterol accumulation and injury in podocytes. Sci.Rep. 7, 10672 (2017).
  
  
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• 参照：
  

• No.： 31
• 文献情報：
  Ohsaki, Y., Maeda, T. & Fujimoto, T. Fixation and permeabilization protocol is critical for the immunolabeling of lipid droplet proteins. Histochem. Cell Biol. 124, 445-452 (2005).
  
  
• 備考：
  
• 参照：
  

• No.： 32
• 文献情報：
  Macpherson, R. E. K. et al. Subcellular localization of skeletal muscle lipid droplets and PLIN family proteins OXPAT and ADRP at rest and following contraction in rat soleus muscle. Am. J. Physiol. - Regul. Integr. Comp. Physiol. -(2011).
  
  
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• 参照：
  

• No.： 33
• 文献情報：
  Straub, B. K., Stoeffel, P., Heid, H., Zimbelmann, R. & Schirmacher, P. Differential pattern of lipid droplet-associated proteins and de novo perilipin expression in hepatocyte steatogenesis. Hepatology 47, 1936-1946 (2008).
  
  
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• 参照：
  

• No.： 34
• 文献情報：
  Maya-Monteiro CM et al. Lipid Droplets Accumulate in the Hypothalamus of Mice and Humans with and without Metabolic Diseases. Neuroendocrinology 2021;111(3):263-272
  Maya-Monteiro CM et al
  2021/01/01
  
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• No.： 35
• 文献情報：
  Maier, A. et al. Hypoxia-inducible protein 2 Hig2/Hilpda mediates neutral lipid accumulation in macrophages and contributes to atherosclerosis in apolipoprotein E-deficient mice. FASEB.J. 31, 4971-4984 (2017)
  
  
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• No.： 36
• 文献情報：
  Fernandez-Rojo, M. A. et al. Caveolin-1 Is Necessary for Hepatic Oxidative Lipid Metabolism: Evidence for Crosstalk between Caveolin-1 and Bile Acid Signaling. Cell Rep. 4, 238-247 (2013).
  
  
• 備考：
  
• 参照：
  

• No.： 37
• 文献情報：
  Chang, B. H.-J., Li, L., Saha, P. & Chan, L. Absence of adipose differentiation related protein upregulates hepatic VLDL secretion, relieves hepatosteatosis, and improves whole body insulin resistance in leptin-deficient mice. J. Lipid Res. 51, 2132-42 (
  
  
• 備考：
  
• 参照：
  

• No.： 38
• 文献情報：
  Akhtar, N. et al. Molecular dissection of integrin signalling proteins in the control of mammary epithelial development and differentiation. Development 136, 1019-27 (2009).
  
  
• 備考：
  
• 参照：
  

• No.： 39
• 文献情報：
  Heid, H. W., Lzer, M. S. & Keenan, T. W. Adipocyte differentiation-related protein is secreted into milk as a constituent of milk lipid globule membrane. Biochem. J. 320, 1025-1030 (1996).
  
  
• 備考：
  
• 参照：
  

• No.： 40
• 文献情報：
  Pauloin, A. & Chanat, E. Prolactin and epidermal growth factor stimulate adipophilin synthesis in HC11 mouse mammary epithelial cells via the PI3-kinase/Akt/mTOR pathway. Biochim. Biophys. Acta 1823, 987-996 (2012).
  
  
• 備考：
  
• 参照：
  

• No.： 41
• 文献情報：
  Sundberg, J. et al. Sebaceous gland abnormalities in fatty acyl CoA reductase 2 (Far2) null mice result in primary cicatricial alopecia. PLoS.One. 13, e0205775 (2018).
  
  
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• No.： 42
• 文献情報：
  Timmers, S. et al. Paradoxical Increase in TAG and DAG Content Parallel the Insulin Sensitizing Effect of Unilateral DGAT1 Overexpression in Rat Skeletal Muscle. PLoS One 6, (2011).
  
  
• 備考：
  
• 参照：
  

• No.： 43
• 文献情報：
  Kozusko, K. et al. Clinical and molecular characterization of a novel PLIN1 frameshift mutation identified in patients with familial partial lipodystrophy Europe PMC Funders Group. Diabetes 64, 299-310 (2015).
  
  
• 備考：
  
• 参照：
  

• No.： 44
• 文献情報：
  Zhao, L. et al. TDP-43 facilitates milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh. Nat.Commun. 11, 341 (2020)
  
  
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• No.： 45
• 文献情報：
  Minami, S. et al. Lipophagy maintains energy homeostasis in the kidney proximal tubule during prolonged starvation. Autophagy. 13, 1629-1647 (2017)
  
  
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• 参照：
  

• No.： 46
• 文献情報：
  Kuramoto, K. et al. Deficiency of a Lipid Droplet Protein, Perilipin 5, Suppresses Myocardial Lipid Accumulation, Thereby Preventing Type 1 Diabetes- Induced Heart Malfunction. Mol. Cell. Biol. -34, 2721-2731 (2014).
  
  
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• No.： 47
• 文献情報：
  Gallardo-Montejano, V. I. et al. Nuclear Perilipin 5 integrates lipid droplet lipolysis with PGC-1a/SIRT1-dependent transcriptional regulation of mitochondrial function. Nat. Commun. 7, (2016).
  
  
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• 参照：
  

• No.： 48
• 文献情報：
  Heid, H. W., Moll, R., Schwetlick, I., Rackwitz, H. R. & Keenan, T. W. Adipophilin is a specific marker of lipid accumulation in diverse cell types and diseases. Cell Tissue Res. 294, 309-21 (1998).
  
  
• 備考：
  
• 参照：
  

• No.： 49
• 文献情報：
  Kaushik, S. & Cuervo, A. M. Degradation of lipid droplet-associated proteins by chaperone- mediated autophagy facilitates lipolysis. Nat. Cell Biol. 17, 759-770 (2015).
  
  
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• 参照：
  

• No.： 50
• 文献情報：
  Yamaguchi, T., Omatsu, N., Omukae, A. & Osumi, T. Analysis of interaction partners for perilipin and ADRP on lipid droplets*. Mol. Cell. Biochem. 284, 167-173 (2006).
  
  
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• 参照：
  

• No.： 51
• 文献情報：
  Wagner, C. et al. Lysosomal acid lipase is the major acid retinyl ester hydrolase in cultured human hepatic stellate cells but not essential for retinyl ester degradation. Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids. 1865, 158730 (2020)
  
  
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• No.： 52
• 文献情報：
  San辿, A. et al. SAR1B GTPase is necessary to protect intestinal cells from disorders of lipid homeostasis, oxidative stress, and inflammation. J.Lipid.Res. 60, 1755-1764 (2019)
  
  
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• No.： 53
• 文献情報：
  Whytock, K. et al. Hormone-sensitive lipase preferentially redistributes to lipid droplets associated with perilipin-5 in human skeletal muscle during moderate-intensity exercise. J.Physiol. 596, 2077-2090 (2018)
  
  
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• No.： 54
• 文献情報：
  Krahmer, N. et al. Organellar Proteomics and Phospho-Proteomics Reveal Subcellular Reorganization in Diet-Induced Hepatic Steatosis. Dev.Cell. 47, 205-221.e7 (2018)
  
  
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• No.： 55
• 文献情報：
  Scantlebery, A. et al. The dysregulation of metabolic pathways and induction of the pentose phosphate pathway in renal ischaemia-reperfusion injury. J Pathol. 253, 404-414(2021).
  
  
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• No.： 56
• 文献情報：
  Heier, C. et al. The phospholipase PNPLA7 functions as a lysophosphatidylcholine hydrolase and interacts with lipid droplets through its catalytic domain. J.Biol.Chem. 292, 19087-19098 (2017).
  
  
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• No.： 57
• 文献情報：
  Gouna, G. et al. TREM2-dependent lipid droplet biogenesis in phagocytes is required for remyelination. J. Exp. Med. 218, (2021).
  
  
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• No.： 58
• 文献情報：
  Tadepalle, N. et al. Microtubule-dependent and independent roles of spastin in lipid droplet dispersion and biogenesis. Life.Sci.Alliance. 3, (2020)
  
  
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• No.： 59
• 文献情報：
  Fukumoto, S. & Fujimoto, T. Deformation of lipid droplets in fixed samples. Histochem. Cell Biol. 118, 423-428 (2002).
  
  
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• 参照：
  

• No.： 60
• 文献情報：
  Lund奪sen, T. et al. The PPAR pan-agonist tetradecylthioacetic acid promotes redistribution of plasma cholesterol towards large HDL. PLoS.One. 15, e0229322 (2020)
  
  
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• No.： 61
• 文献情報：
  Homma, T. et al. Double Knockout of Peroxiredoxin 4 (Prdx4) and Superoxide Dismutase 1 (Sod1) in Mice Results in Severe Liver Failure. Oxid.Med.Cell.Longev. 2018, 2812904 (2018).
  
  
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• No.： 62
• 文献情報：
  Kuramoto K et al. The autophagy protein Becn1 improves insulin sensitivity by promoting adiponectin secretion via exocyst binding. Cell Rep 2021 May;35(8):109184
  Kuramoto K et al
  2021/01/01
  
• 備考：
  
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